Strain Name:
C57BL/6J-MtgxR0842Btlr/Mmmh
Stock Number:
039021-MU
Citation ID:
RRID:MMRRC_039021-MU
Other Names:
R0842 (G1), C57BL/6J-MtgxR0842Btlr
Major Collection:

Gene Information

D630045J12Rik
Name: RIKEN cDNA D630045J12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330286
Homologene: 19782
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Thop1
Name: thimet oligopeptidase 1
Synonyms: EP24.15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 50492
Homologene: 55726
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22390
Homologene: 31152
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, 1110051N18Rik, Zcwcc3, D16Jhu32e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 338467
Homologene: 32257
Nfyc
Name: nuclear transcription factor-Y gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18046
HGNC: HGNC:7806
Homologene: 7440
R3hdm1
Name: R3H domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226412
HGNC: HGNC:9757
Homologene: 9108
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, jdf2, D7H15F37S1, rjs, D15F32S1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: B130055D15Rik, 4632407J06Rik, 2810487N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 78658
VEGA: 9
Homologene: 41021
Myo9a
Name: myosin IXa
Synonyms: C130068I12Rik, 4732465J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Fcho1
Name: FCH domain only 1
Synonyms: 3322402E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74015
Homologene: 22869
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, Dnahc7a, LOC381341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 627872
Homologene: 41287
Angptl8
Name: angiopoietin-like 8
Synonyms: Rifl, Lipasin, Gm6484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 624219
VEGA: 9
Homologene: 83285
Mtr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Synonyms: MS, D830038K18Rik, methionine synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238505
VEGA: 13
HGNC: HGNC:7468
Homologene: 37280
Map4k3
Name: mitogen-activated protein kinase kinase kinase kinase 3
Synonyms: 9530052P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 225028
VEGA: 17
HGNC: HGNC:6865
Homologene: 2683
Ric3
Name: RIC3 acetylcholine receptor chaperone
Synonyms: E130307J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320360
Homologene: 49772
Plagl1
Name: pleiomorphic adenoma gene-like 1
Synonyms: Zac1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22634
HGNC: HGNC:9046
Homologene: 31401
Pmpcb
Name: peptidase (mitochondrial processing) beta
Synonyms: MPP11, MPPP52, 3110004O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 73078
HGNC: HGNC:9119
Homologene: 3160
Tnik
Name: TRAF2 and NCK interacting kinase
Synonyms: 4831440I19Rik, 1500031A17Rik, C530008O15Rik, C630040K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 665113
Homologene: 77943
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 104271
Homologene: 12837
Tbc1d20
Name: TBC1 domain family, member 20
Synonyms: 1110028I04Rik, bs, 2810442O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67231
Homologene: 32574
Nlrp14
Name: NLR family, pyrin domain containing 14
Synonyms: Nalp14, 4921520L01Rik, GC-LRR, Nalp-iota
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76858
Homologene: 18531
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: Myhsf1, Myhs-f1, MyHC-IIa, MHC2A, Myhs-f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Ggt6
Name: gamma-glutamyltransferase 6
Synonyms: 9030405D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71522
Homologene: 51918
L3mbtl4
Name: L3MBTL4 histone methyl-lysine binding protein
Synonyms: A730037L19Rik, D930040M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320858
Homologene: 114383
Filip1
Name: filamin A interacting protein 1
Synonyms: FILIP, 5730485H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70598
Homologene: 6700
Gm281
Name: predicted gene 281
Synonyms: LOC238939
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 238939
HGNC: null
Homologene: 141164
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Pacsin2
Name: protein kinase C and casein kinase substrate in neurons 2
Synonyms: Syndapin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 23970
VEGA: 15
HGNC: HGNC:8571
Homologene: 21414
Eme1
Name: essential meiotic structure-specific endonuclease 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268465
Homologene: 16123
F11
Name: coagulation factor XI
Synonyms: plasma thromboplastin antecedent, Cf11, 1600027G01Rik, FXI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109821
HGNC: HGNC:3529
Homologene: 86654
Fap
Name: fibroblast activation protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14089
HGNC: HGNC:3590
Homologene: 48282
Nat3
Name: N-acetyltransferase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17962
Homologene: 69026
Socs4
Name: suppressor of cytokine signaling 4
Synonyms: Socs7, 3110032M18Rik, A730004F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 67296
Homologene: 15442
Zscan29
Name: zinc finger SCAN domains 29
Synonyms: Zfp690
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99334
Homologene: 17586
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 636808
Homologene: 43974
Cilp2
Name: cartilage intermediate layer protein 2
Synonyms: 1110031K21Rik, CLIP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 68709
Homologene: 17713
Thoc2l
Name: THO complex subunit 2-like
Synonyms: BC005561, Gm3179
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100042165
HGNC: null
Homologene: null
Pou2f2
Name: POU domain, class 2, transcription factor 2
Synonyms: Oct2d, Otf-2, Oct-2, Oct2a, Oct2b, Oct2c, Otf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18987
HGNC: HGNC:9213
Homologene: 55674
Apbb1ip
Name: amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Synonyms: 9930118P07Rik, Prp48, proline-rich protein 48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 54519
Homologene: 32434
AC110527.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Samhd1
Name: SAM domain and HD domain, 1
Synonyms: E330031J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56045
Homologene: 9160
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224576
HGNC: null
Homologene: 135824
Klrb1
Name: killer cell lectin-like receptor subfamily B member 1
Synonyms: Ly55, 4930431A04Rik, Nkrp1g, Ly-55, Gm4696
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 100043861
HGNC: null
Homologene: 135763
Hhat
Name: hedgehog acyltransferase
Synonyms: Skn, 2810432O22Rik, AP-2CRE, Tg(TFAP2A-cre)1Will
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226861
Homologene: 41232
Ldha
Name: lactate dehydrogenase A
Synonyms: Ldh-1, LDH-A, lactate dehydrogenase-A, l7R2, Ldh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16828
HGNC: HGNC:6535
Homologene: 56495
Catsperb
Name: cation channel sperm associated auxiliary subunit beta
Synonyms: 4932415G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 271036
VEGA: 12
Homologene: 81904
Rab1b
Name: RAB1B, member RAS oncogene family
Synonyms: 1110011F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 76308
VEGA: 19
Homologene: 128838
Fam155a
Name: family with sequence similarity 155, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270028
Homologene: 83472
Colca2
Name: COLCA2 homolog
Synonyms: Gm684, LOC270157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100502940
VEGA: 9
Homologene: 19023
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 53,501,674 bp
  • G to A, chromosome 1 at 116,442,223 bp
  • T to C, chromosome 1 at 128,178,879 bp
  • C to T, chromosome 1 at 141,257,142 bp
  • T to C, chromosome 1 at 192,726,331 bp
  • G to A, chromosome 2 at 22,867,666 bp
  • A to T, chromosome 2 at 62,537,001 bp
  • T to A, chromosome 2 at 121,161,479 bp
  • AGGACGG to AGGACGGACGG, chromosome 2 at 152,294,047 bp
  • A to G, chromosome 2 at 157,123,331 bp
  • A to G, chromosome 3 at 28,594,086 bp
  • C to A, chromosome 4 at 120,759,377 bp
  • T to C, chromosome 5 at 21,748,774 bp
  • T to A, chromosome 5 at 104,519,200 bp
  • A to T, chromosome 6 at 38,148,465 bp
  • A to G, chromosome 6 at 128,710,045 bp
  • A to T, chromosome 7 at 25,096,930 bp
  • A to T, chromosome 7 at 46,852,005 bp
  • A to C, chromosome 7 at 56,121,705 bp
  • A to G, chromosome 7 at 107,183,135 bp
  • T to C, chromosome 7 at 109,038,880 bp
  • T to C, chromosome 7 at 110,126,174 bp
  • T to A, chromosome 8 at 9,770,114 bp
  • T to A, chromosome 8 at 33,571,547 bp
  • T to C, chromosome 8 at 45,252,159 bp
  • T to C, chromosome 8 at 67,547,997 bp
  • T to C, chromosome 8 at 69,883,118 bp
  • C to T, chromosome 8 at 71,712,560 bp
  • C to A, chromosome 9 at 21,835,676 bp
  • C to T, chromosome 9 at 27,037,084 bp
  • T to C, chromosome 9 at 51,272,368 bp
  • C to A, chromosome 9 at 59,871,067 bp
  • C to T, chromosome 9 at 79,860,071 bp
  • G to T, chromosome 10 at 13,128,554 bp
  • C to A, chromosome 10 at 81,075,577 bp
  • C to T, chromosome 11 at 67,179,524 bp
  • T to A, chromosome 11 at 72,437,262 bp
  • C to T, chromosome 11 at 94,650,874 bp
  • A to T, chromosome 12 at 101,463,048 bp
  • A to C, chromosome 13 at 12,200,247 bp
  • C to A, chromosome 13 at 13,678,241 bp
  • G to A, chromosome 14 at 13,856,686 bp
  • T to A, chromosome 14 at 47,289,969 bp
  • T to C, chromosome 15 at 83,379,181 bp
  • T to C, chromosome 16 at 93,873,396 bp
  • T to A, chromosome 17 at 20,268,203 bp
  • T to A, chromosome 17 at 68,486,962 bp
  • T to C, chromosome 17 at 80,605,983 bp
  • A to T, chromosome 19 at 5,104,669 bp
  • T to C, chromosome 19 at 56,345,454 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0842 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039021-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.