Strain Name:
C57BL/6J-MtgxR0849Btlr/Mmmh
Stock Number:
039028-MU
Citation ID:
RRID:MMRRC_039028-MU
Other Names:
R0849 (G1), C57BL/6J-MtgxR0849Btlr
Major Collection:

Gene Information

Fezf2
Name: Fez family zinc finger 2
Synonyms: Zfp312, Fezl, Fez, forebrain embryonic zinc finger
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 54713
VEGA: 14
Homologene: 9957
Slc1a3
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Synonyms: B430115D02Rik, Gmt1, MGluT1, GLAST, Eaat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20512
Homologene: 20882
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 104245
Homologene: 37901
Vcan
Name: versican
Synonyms: DPEAAE, heart defect, 5430420N07Rik, hdf, PG-M, Cspg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Grin3a
Name: glutamate receptor ionotropic, NMDA3A
Synonyms: A830097C19Rik, NMDAR-L, NR3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242443
Homologene: 128613
Kpna4
Name: karyopherin (importin) alpha 4
Synonyms: IPOA3, 1110058D08Rik, importin alpha 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16649
HGNC: HGNC:6397
Homologene: 20521
Tbcel
Name: tubulin folding cofactor E-like
Synonyms: Lrrc35, E130107N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 272589
Homologene: 16120
Armc9
Name: armadillo repeat containing 9
Synonyms: 3830422A13Rik, 5730415N24Rik, 4831423D23Rik, 4930438O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 78795
Homologene: 11847
Dstn
Name: destrin
Synonyms: 2610043P17Rik, corn1, ADF, sid23p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56431
Homologene: 21362
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, jdf2, D7H15F37S1, rjs, D15F32S1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Atxn2
Name: ataxin 2
Synonyms: 9630045M23Rik, Sca2, ATX2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20239
Homologene: 2234
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, D4Abb1e, 4833432B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100019
Homologene: 39689
Cnot10
Name: CCR4-NOT transcription complex, subunit 10
Synonyms: 2600001P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 78893
VEGA: 9
Homologene: 41040
Rarb
Name: retinoic acid receptor, beta
Synonyms: RARbeta2, Hap, RAR beta 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218772
VEGA: 14
HGNC: HGNC:9865
Homologene: 68100
Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Synonyms: 125kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18971
HGNC: HGNC:9175
Homologene: 2014
Cntn2
Name: contactin 2
Synonyms: TAG1, axonin, Tax, D130012K04Rik, TAG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: Zfp650, 1110059H15Rik, 4833421P10Rik, A130030D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68795
Homologene: 52092
Gm2381
Name: predicted gene 2381
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100039706
Mansc1
Name: MANSC domain containing 1
Synonyms: 9130403P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67729
Homologene: 49522
Cand2
Name: cullin-associated and neddylation-dissociated 2 (putative)
Synonyms: Tp120b, 2210404G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67088
Homologene: 41657
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233810
Homologene: 132942
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: skrr, Ryr, calcium release channel isoform 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20190
Homologene: 68069
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1537Clo, b2b1565Clo, b2b3491Clo, b2b1154Clo, Mdnah5, Dnahc5, b2b1134Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Stard9
Name: START domain containing 9
Synonyms: E230025N21Rik, 4831403C07Rik, Kif16a, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668880
Homologene: 130712
Des
Name: desmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13346
HGNC: HGNC:2770
Homologene: 56469
Eln
Name: elastin
Synonyms: E030024M20Rik, tropoelastin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13717
HGNC: HGNC:3327
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: Gm3812, Liprin-alpha4, 1110008G13Rik, LOC100042382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190-B, p190B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
Arhgef11
Name: Rho guanine nucleotide exchange factor (GEF) 11
Synonyms: PDZ-RhoGEF, Prg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213498
Homologene: 11409
Irf2bp1
Name: interferon regulatory factor 2 binding protein 1
Synonyms: 6330414O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 272359
Homologene: 32276
Cntn4
Name: contactin 4
Synonyms: Axcam, BIG-2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 269784
HGNC: HGNC:2174
Homologene: 14257
Nrxn1
Name: neurexin I
Synonyms: neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I alpha, A230068P09Rik, 1700062G21Rik, neurexin I alpha, neurexin I beta, alpha-latrotoxin receptor (calcium-dependent), 9330127H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Myo5c
Name: myosin VC
Synonyms: 9130003O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208943
VEGA: 9
HGNC: HGNC:7604
Homologene: 135711
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Olfr1380
Name: olfactory receptor 1380
Synonyms: GA_x6K02T2QP88-5871967-5871032, MOR256-66_i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 404336
Homologene: 72463
1300017J02Rik
Name: RIKEN cDNA 1300017J02 gene
Synonyms: mICA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71775
Homologene: 826
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240776
Homologene: 16121
Olfr1131
Name: olfactory receptor 1131
Synonyms: MOR177-4, GA_x6K02T2Q125-49133664-49134593
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258652
Homologene: 133019
Tmem38b
Name: transmembrane protein 38B
Synonyms: TRIC-B, 1600017F22Rik, D4Ertd89e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 52076
Homologene: 10010
Vmn2r22
Name: vomeronasal 2, receptor 22
Synonyms: EG546913
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 546913
Homologene: 84037
Scnn1b
Name: sodium channel, nonvoltage-gated 1 beta
Synonyms: ENaC beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20277
Homologene: 133555
Nek4
Name: NIMA (never in mitosis gene a)-related expressed kinase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 23955
VEGA: 14
Homologene: 2376
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Fafl2, Dffry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 107868
Homologene: 68408
Tmtc4
Name: transmembrane and tetratricopeptide repeat containing 4
Synonyms: 5730419O14Rik, 4930403J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 70551
Homologene: 32796
Sv2c
Name: synaptic vesicle glycoprotein 2c
Synonyms: 4930527L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75209
Homologene: 57152
Ssx2ip
Name: synovial sarcoma, X 2 interacting protein
Synonyms: Adip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99167
Homologene: 8522
Hs3st2
Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 2
Synonyms: 6430516N12Rik, A830061E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 195646
HGNC: HGNC:5195
Homologene: 21220
Olfr1120
Name: olfactory receptor 1120
Synonyms: MOR264-2, GA_x6K02T2Q125-48849180-48850100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 259031
Homologene: 72054
B3gnt6
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
Synonyms: Core-3, Core3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 272411
Homologene: 16339
Mrgprb4
Name: MAS-related GPR, member B4
Synonyms: MrgB4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233230
Homologene: 115575
Vmn2r126
Name: vomeronasal 2, receptor 126
Synonyms: Gm9268
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 668612
Homologene: 104832
Tas2r109
Name: taste receptor, type 2, member 109
Synonyms: mt2r62, T2R09, Tas2r9, mGR09
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387343
Homologene: 87292
Tmem35b
Name: transmembrane protein 35B
Synonyms: Zmym6nb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100039968
Homologene: 106612
Msmo1
Name: methylsterol monoxygenase 1
Synonyms: 1500001G16Rik, C78600, DESP4, ERG25, Sc4mol
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66234
Homologene: 133932
Gm14183
Name: predicted gene 14183
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 75,360,628 bp
  • G to A, chromosome 1 at 86,257,270 bp
  • A to T, chromosome 1 at 132,522,386 bp
  • A to T, chromosome 1 at 134,319,372 bp
  • T to C, chromosome 1 at 140,507,762 bp
  • G to T, chromosome 2 at 69,971,053 bp
  • G to T, chromosome 2 at 87,358,265 bp
  • C to A, chromosome 2 at 87,629,282 bp
  • C to A, chromosome 2 at 120,673,636 bp
  • G to A, chromosome 2 at 143,938,535 bp
  • A to T, chromosome 3 at 69,087,600 bp
  • G to T, chromosome 3 at 87,735,896 bp
  • A to G, chromosome 3 at 96,652,530 bp
  • T to C, chromosome 3 at 146,418,459 bp
  • T to A, chromosome 4 at 32,741,835 bp
  • G to A, chromosome 4 at 49,665,501 bp
  • T to C, chromosome 4 at 53,840,765 bp
  • A to G, chromosome 4 at 127,126,197 bp
  • T to A, chromosome 5 at 121,747,421 bp
  • T to A, chromosome 5 at 134,707,981 bp
  • A to T, chromosome 6 at 106,667,457 bp
  • A to G, chromosome 6 at 115,792,391 bp
  • T to C, chromosome 6 at 123,637,404 bp
  • T to C, chromosome 6 at 132,980,893 bp
  • T to C, chromosome 6 at 134,610,707 bp
  • T to C, chromosome 7 at 19,004,734 bp
  • A to G, chromosome 7 at 29,040,679 bp
  • G to A, chromosome 7 at 42,819,948 bp
  • A to G, chromosome 7 at 43,024,718 bp
  • A to G, chromosome 7 at 44,541,025 bp
  • G to A, chromosome 7 at 48,199,120 bp
  • C to A, chromosome 7 at 49,938,408 bp
  • T to A, chromosome 7 at 56,206,578 bp
  • C to A, chromosome 7 at 98,194,743 bp
  • T to C, chromosome 7 at 120,465,670 bp
  • A to G, chromosome 7 at 121,501,032 bp
  • A to G, chromosome 7 at 121,912,475 bp
  • A to G, chromosome 8 at 64,720,504 bp
  • G to A, chromosome 8 at 110,598,984 bp
  • A to C, chromosome 9 at 42,437,157 bp
  • C to A, chromosome 9 at 75,284,216 bp
  • A to C, chromosome 9 at 103,263,057 bp
  • T to C, chromosome 9 at 114,601,327 bp
  • G to A, chromosome 11 at 49,564,302 bp
  • A to T, chromosome 11 at 99,705,024 bp
  • T to C, chromosome 12 at 52,519,623 bp
  • A to T, chromosome 13 at 89,704,953 bp
  • C to T, chromosome 13 at 95,989,811 bp
  • T to A, chromosome 14 at 12,342,607 bp
  • A to G, chromosome 14 at 16,434,293 bp
  • A to G, chromosome 14 at 30,957,296 bp
  • A to G, chromosome 14 at 122,945,554 bp
  • T to C, chromosome 15 at 8,639,049 bp
  • C to A, chromosome 15 at 28,263,599 bp
  • A to T, chromosome 17 at 90,565,292 bp
  • C to A, chromosome Y at 1,394,002 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0849 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039028-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.