Strain Name:
C57BL/6J-MtgxR0892Btlr/Mmmh
Stock Number:
039055-MU
Citation ID:
RRID:MMRRC_039055-MU
Other Names:
R0892 (G1), C57BL/6J-MtgxR0892Btlr
Major Collection:

Gene Information

Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: Spnb-2, 9930031C03Rik, elf3, elf1, brain spectrin, Spnb2, beta fodrin, non-erythrocytic, spectrin G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20742
Homologene: 2354
Gpr37
Name: G protein-coupled receptor 37
Synonyms: parkin-associated endothelin B-like receptor, Pael-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14763
HGNC: HGNC:4494
Homologene: 3875
Gpa33
Name: glycoprotein A33 (transmembrane)
Synonyms: A33 antigen, 2210401D16Rik, 2010310L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 59290
HGNC: HGNC:4445
Homologene: 4245
Trappc8
Name: trafficking protein particle complex 8
Synonyms: Trs85, D030074E01Rik, 5033403J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75964
VEGA: 18
Homologene: 40993
Lamc1
Name: laminin, gamma 1
Synonyms: laminin B2, Lamb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226519
HGNC: HGNC:6492
Homologene: 1724
Epg5
Name: ectopic P-granules autophagy protein 5 homolog (C. elegans)
Synonyms: 5430411K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 100502841
VEGA: 18
Homologene: 14575
Dmkn
Name: dermokine
Synonyms: dermokine, Dmkn, sk89, sk30, cI-36, 1110014F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73712
Homologene: 136295
Bcr
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, breakpoint cluster region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110279
VEGA: 10
HGNC: HGNC:1014
Homologene: 3192
St14
Name: suppression of tumorigenicity 14 (colon carcinoma)
Synonyms: matriptase, MT-SP1, Tmprss14, Epithin, Prss14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19143
Homologene: 7906
Sbsn
Name: suprabasin
Synonyms: 1110005D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 282619
Homologene: 17900
Ell2
Name: elongation factor for RNA polymerase II 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 192657
VEGA: 13
Homologene: 8094
Tatdn3
Name: TatD DNase domain containing 3
Synonyms: 1500010M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68972
Homologene: 45949
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Myh6
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha
Synonyms: alpha myosin, A830009F23Rik, Myhca, Myhc-a, alphaMHC, alpha-MHC, cardiomyopathy, hypertrophic 1, alpha cardiac MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 17888
HGNC: HGNC:7576
Homologene: 124414
Mapre2
Name: microtubule-associated protein, RP/EB family, member 2
Synonyms: D18Abb1e, RP1, EB2, C820009F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 212307
HGNC: HGNC:6891
Homologene: 134539
Olfr1484
Name: olfactory receptor 1484
Synonyms: MOR202-37, GA_x6K02T2RE5P-3917859-3918806
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258288
Homologene: 110492
Sec22c
Name: SEC22 homolog C, vesicle trafficking protein
Synonyms: 5930407I15Rik, Sec22l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215474
Homologene: 41948
Prorp
Name: protein only RNase P catalytic subunit
Synonyms: 1110008L16Rik, Mrpp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66132
Homologene: 45935
Hpse2
Name: heparanase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 545291
VEGA: 19
Homologene: 19680
Plag1
Name: pleiomorphic adenoma gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56711
HGNC: HGNC:9045
Homologene: 1993
Bace2
Name: beta-site APP-cleaving enzyme 2
Synonyms: ASP21, CDA13, ALP56, BAE2, ARP1, CEAP1, 1110059C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56175
VEGA: 16
HGNC: HGNC:934
Homologene: 22696
Cd46
Name: CD46 antigen, complement regulatory protein
Synonyms: Mcp, CD46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17221
HGNC: HGNC:6953
Homologene: 7832
Itgax
Name: integrin alpha X
Synonyms: CD11C (p150) alpha polypeptide, Cd11c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16411
HGNC: HGNC:6152
Homologene: 55493
Pom121l2
Name: POM121 membrane glycoprotein-like 2 (rat)
Synonyms: LOC195236
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 195236
Homologene: 123536
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: developmental endothelial locus-1, Del-1, Del1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Ankub1
Name: ankyrin repeat and ubiquitin domain containing 1
Synonyms: LOC242037, Gm410
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242037
Homologene: 54680
Oog2
Name: oogenesin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381570
Homologene: 77858
Gm10242
Name: predicted gene 10242
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100040589
Msmo1
Name: methylsterol monoxygenase 1
Synonyms: Sc4mol, C78600, ERG25, DESP4, 1500001G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66234
Homologene: 133932
Gm15737
Name: predicted gene 15737
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Slc25a42
Name: solute carrier family 25, member 42
Synonyms: 2900084M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73095
Homologene: 74852
Bin1
Name: bridging integrator 1
Synonyms: Amphl, Amphiphysin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 30948
VEGA: 18
HGNC: HGNC:1052
Homologene: 113707
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 153,332,254 bp
  • A to G, chromosome 1 at 166,157,642 bp
  • T to C, chromosome 1 at 191,062,805 bp
  • T to C, chromosome 1 at 195,082,612 bp
  • T to C, chromosome 3 at 57,690,379 bp
  • G to A, chromosome 4 at 3,904,532 bp
  • A to T, chromosome 4 at 144,196,499 bp
  • A to T, chromosome 6 at 25,688,207 bp
  • A to T, chromosome 6 at 48,939,935 bp
  • C to T, chromosome 6 at 92,879,740 bp
  • A to T, chromosome 7 at 30,754,819 bp
  • C to T, chromosome 7 at 30,767,404 bp
  • T to C, chromosome 7 at 128,148,129 bp
  • T to A, chromosome 8 at 64,722,553 bp
  • A to G, chromosome 8 at 70,191,947 bp
  • A to T, chromosome 9 at 31,100,428 bp
  • C to T, chromosome 9 at 121,695,529 bp
  • C to T, chromosome 10 at 75,125,063 bp
  • T to A, chromosome 11 at 9,298,305 bp
  • C to A, chromosome 11 at 30,142,201 bp
  • A to G, chromosome 12 at 55,382,248 bp
  • A to G, chromosome 13 at 21,982,474 bp
  • A to T, chromosome 13 at 75,763,639 bp
  • T to C, chromosome 13 at 89,131,669 bp
  • T to C, chromosome 14 at 54,947,054 bp
  • T to C, chromosome 16 at 97,408,504 bp
  • A to G, chromosome 18 at 20,831,608 bp
  • A to G, chromosome 18 at 23,858,143 bp
  • G to A, chromosome 18 at 32,432,440 bp
  • T to A, chromosome 18 at 77,968,628 bp
  • T to A, chromosome 19 at 13,585,517 bp
  • T to C, chromosome 19 at 43,388,146 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0892 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039055-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.