Strain Name:
C57BL/6J-MtgxR0919Btlr/Mmmh
Stock Number:
039069-MU
Citation ID:
RRID:MMRRC_039069-MU
Other Names:
R0919 (G1), C57BL/6J-MtgxR0919Btlr
Major Collection:

Gene Information

Sash1
Name: SAM and SH3 domain containing 1
Synonyms: A330076K04Rik, 1100001C18Rik, 2500002E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70097
Homologene: 69182
U2af2
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22185
Homologene: 110853
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: slip, DNA-PK, DNAPDcs, dxnph, DOXNPH, DNA-PKcs, XRCC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: D5Bwg1524e, 2410098H20Rik, Rutbc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 52850
Homologene: 64485
Kpna4
Name: karyopherin (importin) alpha 4
Synonyms: IPOA3, 1110058D08Rik, importin alpha 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16649
HGNC: HGNC:6397
Homologene: 20521
Txn2
Name: thioredoxin 2
Synonyms: Trx2, 2510006J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 56551
Homologene: 40849
Washc2
Name: WASH complex subunit 2`
Synonyms: Fam21, C530005J20Rik, D6Wsu116e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28006
Homologene: 41686
Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Synonyms: LTRPC7, 5033407O22Rik, CHAK1, CHAK, 2310022G15Rik, Ltpr7, TRP-PLIK, 4833414K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58800
Homologene: 9774
Btaf1
Name: B-TFIID TATA-box binding protein associated factor 1
Synonyms: E430027O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107182
Homologene: 31978
Sfmbt2
Name: Scm-like with four mbt domains 2
Synonyms: D2Wsu23e, D330030P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 353282
Homologene: 82485
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, Mcpr, Apc1, 2610021O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17222
Homologene: 7414
Scaf8
Name: SR-related CTD-associated factor 8
Synonyms: Rbm16, A930036P18Rik, A630086M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106583
VEGA: 17
Homologene: 8928
Ubn1
Name: ubinuclein 1
Synonyms: 1110029L11Rik, 2610108L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 170644
VEGA: 16
Homologene: 9656
Ubtf
Name: upstream binding transcription factor, RNA polymerase I
Synonyms: UBF, UBF1, A930005G04Rik, Tcfubf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 21429
Homologene: 7970
Htr1a
Name: 5-hydroxytryptamine (serotonin) receptor 1A
Synonyms: 5-HT1A receptor, Gpcr18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 15550
VEGA: 13
HGNC: HGNC:5286
Homologene: 20148
Prkrip1
Name: Prkr interacting protein 1 (IL11 inducible)
Synonyms: C114, 8430424D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66801
Homologene: 6323
Osbpl7
Name: oxysterol binding protein-like 7
Synonyms: 4933437E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71240
Homologene: 79672
Timm21
Name: translocase of inner mitochondrial membrane 21
Synonyms: 2700002I20Rik, 1700034H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 67105
VEGA: 18
Homologene: 32211
Anapc4
Name: anaphase promoting complex subunit 4
Synonyms: D5Ertd249e, APC4, 2610306D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 52206
Homologene: 40873
Trpc7
Name: transient receptor potential cation channel, subfamily C, member 7
Synonyms: TRP7, Trrp8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 26946
Homologene: 22689
Cfap70
Name: cilia and flagella associated protein 70
Synonyms: 5330402L21Rik, Ttc18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 76670
Homologene: 17048
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Zscan10
Name: zinc finger and SCAN domain containing 10
Synonyms: Zfp206, Zscan10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 332221
Homologene: 13122
Col11a2
Name: collagen, type XI, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12815
HGNC: HGNC:2187
Homologene: 22547
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Slc44a5
Name: solute carrier family 44, member 5
Synonyms: LOC242259
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242259
Homologene: 72094
Synm
Name: synemin, intermediate filament protein
Synonyms: Synemin, 4930412K21Rik, Dmn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233335
Homologene: 9081
Insr
Name: insulin receptor
Synonyms: IR, IR-B, D630014A15Rik, 4932439J01Rik, CD220, IR-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16337
HGNC: HGNC:6091
Homologene: 20090
Prkce
Name: protein kinase C, epsilon
Synonyms: PKCepsilon, PKC[e], 5830406C15Rik, Pkce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18754
HGNC: HGNC:9401
Homologene: 48343
Clcf1
Name: cardiotrophin-like cytokine factor 1
Synonyms: Bsf3, CLC, NNT-1/BSF-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56708
Homologene: 8299
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, D10Bwg1379e, BIG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215821
VEGA: 10
Homologene: 41366
Alpk2
Name: alpha-kinase 2
Synonyms: Hak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225638
Homologene: 50475
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74362
Homologene: 52601
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Olfr1032
Name: olfactory receptor 1032
Synonyms: GA_x6K02T2Q125-47485813-47486745, MOR199-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258572
Homologene: 17299
Dhx34
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 34
Synonyms: 1810012L18Rik, 1200013B07Rik, Ddx34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71723
Homologene: 69171
Cyp2c38
Name: cytochrome P450, family 2, subfamily c, polypeptide 38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13097
HGNC: HGNC:2622
Homologene: 117948
Slc38a3
Name: solute carrier family 38, member 3
Synonyms: Snat3, 0610012J02Rik, D9Ucla2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 76257
Homologene: 4983
Usp49
Name: ubiquitin specific peptidase 49
Synonyms: C330046L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224836
Homologene: 10235
Tbc1d12
Name: TBC1D12: TBC1 domain family, member 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 209478
VEGA: 19
Homologene: 50835
Olfr607
Name: olfactory receptor 607
Synonyms: MOR33-3P, EG546989, GA_x6K02T2PBJ9-6182881-6181898, Gm15121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546989
Homologene: 78211
2610301B20Rik
Name: RIKEN cDNA 2610301B20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67157
Homologene: 18641
Olfr671
Name: olfactory receptor 671
Synonyms: MOR32-12, GA_x6K02T2PBJ9-7604826-7603885
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 257910
Homologene: 133595
Dbpht2
Name: DNA binding protein with his-thr domain
Synonyms: Spot2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 386753
VEGA: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 2 at 10,577,571 bp
  • T to A, chromosome 2 at 76,946,742 bp
  • T to A, chromosome 2 at 82,985,484 bp
  • A to G, chromosome 2 at 86,008,640 bp
  • G to A, chromosome 2 at 126,831,238 bp
  • T to C, chromosome 2 at 128,617,731 bp
  • A to T, chromosome 3 at 69,085,828 bp
  • C to T, chromosome 3 at 96,651,738 bp
  • A to T, chromosome 3 at 100,071,943 bp
  • A to G, chromosome 3 at 154,243,586 bp
  • A to G, chromosome 4 at 10,882,462 bp
  • T to C, chromosome 5 at 52,855,637 bp
  • C to T, chromosome 5 at 113,258,842 bp
  • T to C, chromosome 5 at 136,197,831 bp
  • C to T, chromosome 6 at 116,208,264 bp
  • C to T, chromosome 7 at 5,069,434 bp
  • A to C, chromosome 7 at 16,201,958 bp
  • T to C, chromosome 7 at 67,735,347 bp
  • A to G, chromosome 7 at 103,460,812 bp
  • A to T, chromosome 7 at 104,975,312 bp
  • A to G, chromosome 8 at 3,158,769 bp
  • A to T, chromosome 9 at 107,655,959 bp
  • A to G, chromosome 10 at 8,730,079 bp
  • A to G, chromosome 10 at 18,589,735 bp
  • G to A, chromosome 11 at 97,056,101 bp
  • A to G, chromosome 11 at 102,309,777 bp
  • A to G, chromosome 12 at 74,299,000 bp
  • C to T, chromosome 13 at 56,822,649 bp
  • T to C, chromosome 13 at 105,444,836 bp
  • G to A, chromosome 14 at 20,404,164 bp
  • T to C, chromosome 15 at 77,927,749 bp
  • T to C, chromosome 16 at 5,064,391 bp
  • T to C, chromosome 16 at 15,667,575 bp
  • T to C, chromosome 17 at 3,197,120 bp
  • T to C, chromosome 17 at 23,610,007 bp
  • T to A, chromosome 17 at 34,059,150 bp
  • T to A, chromosome 17 at 47,672,451 bp
  • G to A, chromosome 17 at 86,630,160 bp
  • C to A, chromosome 18 at 65,307,473 bp
  • G to C, chromosome 18 at 84,949,262 bp
  • T to A, chromosome 19 at 4,222,198 bp
  • T to A, chromosome 19 at 36,990,743 bp
  • C to T, chromosome 19 at 38,914,049 bp
  • T to G, chromosome 19 at 39,404,669 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0919 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039069-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.