Strain Name:
C57BL/6J-MtgxR0927Btlr/Mmmh
Stock Number:
039074-MU
Citation ID:
RRID:MMRRC_039074-MU
Other Names:
R0927 (G1), C57BL/6J-MtgxR0927Btlr
Major Collection:

Strain Information

Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: beta fodrin, Spnb-2, spectrin G, brain spectrin, elf3, elf1, 9930031C03Rik, non-erythrocytic, Spnb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20742
Homologene: 2354
Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77569
Homologene: 18953
Herc3
Name: hect domain and RLD 3
Synonyms: 5730409F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73998
HGNC: HGNC:4876
Homologene: 57095
Kcns2
Name: K+ voltage-gated channel, subfamily S, 2
Synonyms: Kv9.2, E130006J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16539
VEGA: 15
HGNC: HGNC:6301
Homologene: 22465
Chtf8
Name: CTF8, chromosome transmission fidelity factor 8
Synonyms: 5830457O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 214987
Homologene: 84588
Ubtd1
Name: ubiquitin domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226122
VEGA: 19
Homologene: 11799
Arpp19
Name: cAMP-regulated phosphoprotein 19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 59046
Homologene: 21318
Kcnj8
Name: potassium inwardly-rectifying channel, subfamily J, member 8
Synonyms: Kir6.1, sltr, slmbr, gnite
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16523
HGNC: HGNC:6269
Homologene: 3654
Clcn6
Name: chloride channel, voltage-sensitive 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26372
HGNC: HGNC:2024
Homologene: 985
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: Lba, D3Ertd775e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Arfgap2
Name: ADP-ribosylation factor GTPase activating protein 2
Synonyms: 2310032E02Rik, Zfp289
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77038
Homologene: 8735
Tcf7l2
Name: transcription factor 7 like 2, T cell specific, HMG box
Synonyms: TCF4E, TCF4B, mTcf-4E, mTcf-4B, Tcf-4, Tcf4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 21416
Homologene: 7564
Rnf20
Name: ring finger protein 20
Synonyms: 4833430L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109331
Homologene: 5571
Abcb8
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Synonyms: 4833412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74610
HGNC: HGNC:49
Homologene: 5203
Cdc27
Name: cell division cycle 27
Synonyms: APC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217232
HGNC: HGNC:1728
Homologene: 960
Pmf1
Name: polyamine-modulated factor 1
Synonyms: 2600009M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67037
Homologene: 5224
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: C530005A01Rik, 6030465E24Rik, spastic paraplegia 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214585
Homologene: 41614
Thap1
Name: THAP domain containing, apoptosis associated protein 1
Synonyms: 4833431A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73754
Homologene: 10005
Dzip3
Name: DAZ interacting protein 3, zinc finger
Synonyms: 6430549P11Rik, 2310047C04Rik, 2A-HUB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224170
Homologene: 8771
Or4m1
Name: olfactory receptor family 4 subfamily M member 1
Synonyms: GA_x6K02T2PMLR-6013665-6012724, MOR242-1, Olfr734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258658
Homologene: 51759
Adam12
Name: a disintegrin and metallopeptidase domain 12 (meltrin alpha)
Synonyms: Mltna, ADAM12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11489
HGNC: HGNC:190
Homologene: 74862
Lrrtm1
Name: leucine rich repeat transmembrane neuronal 1
Synonyms: 4632401D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74342
Homologene: 41763
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Gtl5, Wcrf180, Acf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Scmh1
Name: sex comb on midleg homolog 1
Synonyms: Scml3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 29871
Homologene: 32146
Reck
Name: reversion-inducing-cysteine-rich protein with kazal motifs
Synonyms: St15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53614
Homologene: 9622
Pomgnt1
Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase
Synonyms: 0610016I07Rik, 4930467B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68273
Homologene: 9806
Cmtr1
Name: cap methyltransferase 1
Synonyms: 1300018I05Rik, Ftsjd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74157
Homologene: 9003
Enam
Name: enamelin
Synonyms: abte
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13801
HGNC: HGNC:3344
Homologene: 9698
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 620292
VEGA: 17
Homologene: 128806
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668940
Homologene: 66117
Ifit2
Name: interferon-induced protein with tetratricopeptide repeats 2
Synonyms: Ifi54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 15958
HGNC: HGNC:5409
Homologene: 1187
Pus3
Name: pseudouridine synthase 3
Synonyms: 2610020J05Rik, 5730412F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67049
Homologene: 11339
Slc36a2
Name: solute carrier family 36 (proton/amino acid symporter), member 2
Synonyms: PAT2, A530067G19Rik, Tramd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246049
Homologene: 72100
Wdr64
Name: WD repeat domain 64
Synonyms: 4930415O10Rik, 4930511H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75820
Homologene: 51634
Adcy5
Name: adenylate cyclase 5
Synonyms: AC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224129
VEGA: 16
HGNC: HGNC:236
Homologene: 11213
Adam34l
Name: a disintegrin and metallopeptidase domain 34 like
Synonyms: Gm5346
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 384813
Homologene: 78104
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 252866
Homologene: 78104
Or10w1
Name: olfactory receptor family 10 subfamily W member 1
Synonyms: GA_x6K02T2RE5P-3987000-3987950, MOR266-6P, Olfr1490
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258098
Homologene: 79418
Fbxw10
Name: F-box and WD-40 domain protein 10
Synonyms: SM2SH2, SM25H2, Fbw10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 213980
Homologene: 32757
Edar
Name: ectodysplasin-A receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13608
HGNC: HGNC:2895
Homologene: 7699
Nrxn1
Name: neurexin I
Synonyms: alpha-latrotoxin receptor (calcium-dependent), neurexin I beta, neurexin I alpha, neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I alpha, 1700062G21Rik, A230068P09Rik, 9330127H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Or11g2
Name: olfactory receptor family 11 subfamily G member 2
Synonyms: GA_x6K02T2PMLR-6326342-6327313, MOR106-13P, Olfr744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 257884
Homologene: 128063
Zbtb26
Name: zinc finger and BTB domain containing 26
Synonyms: A630026F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320633
Homologene: 10853
Adam7
Name: a disintegrin and metallopeptidase domain 7
Synonyms: EAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11500
HGNC: HGNC:214
Homologene: 2830
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277360
Homologene: 10821
Sidt1
Name: SID1 transmembrane family, member 1
Synonyms: B830021E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320007
Homologene: 41189
Or7e166
Name: olfactory receptor family 7 subfamily E member 166
Synonyms: GA_x6K02T2PVTD-13452606-13453535, MOR146-8P, Olfr857
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 257963
Homologene: 134093
Slc47a1
Name: solute carrier family 47, member 1
Synonyms: 1300013J15Rik, MATE1, mMATE1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67473
Homologene: 34364
Kif12
Name: kinesin family member 12
Synonyms: N-9 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16552
Homologene: 7796
Zbtb24
Name: zinc finger and BTB domain containing 24
Synonyms: ZNF450
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 268294
VEGA: 10
Homologene: 8870
Grin3b
Name: glutamate receptor, ionotropic, NMDA3B
Synonyms: NR3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 170483
Homologene: 15606
Ubash3b
Name: ubiquitin associated and SH3 domain containing, B
Synonyms: 2810457I06Rik, TULA-2, Sts-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72828
Homologene: 13152
Glra3
Name: glycine receptor, alpha 3 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 110304
HGNC: HGNC:4328
Homologene: 142
Pfkfb3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms: E330010H22Rik, uPFK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 170768
HGNC: HGNC:8874
Homologene: 88708
Nudt6
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229228
HGNC: HGNC:8053
Homologene: 31425
Sirt6
Name: sirtuin 6
Synonyms: 2810449N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 50721
Homologene: 6924
Tedc1
Name: tubulin epsilon and delta complex 1
Synonyms: 4930427A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104732
Homologene: 77129
Zcchc24
Name: zinc finger, CCHC domain containing 24
Synonyms: 2310047A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71918
Homologene: 66746
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 175,793,081 bp
  • T to A, chromosome 2 at 11,488,722 bp
  • T to C, chromosome 2 at 37,436,325 bp
  • T to C, chromosome 2 at 91,273,805 bp
  • T to A, chromosome 2 at 122,094,487 bp
  • A to G, chromosome 2 at 155,620,120 bp
  • C to T, chromosome 2 at 166,586,537 bp
  • C to T, chromosome 3 at 37,405,353 bp
  • T to C, chromosome 3 at 86,780,233 bp
  • A to T, chromosome 3 at 88,396,062 bp
  • A to T, chromosome 4 at 43,895,837 bp
  • T to C, chromosome 4 at 49,642,176 bp
  • T to C, chromosome 4 at 63,168,773 bp
  • T to A, chromosome 4 at 116,151,851 bp
  • T to C, chromosome 4 at 120,468,475 bp
  • T to A, chromosome 4 at 143,654,220 bp
  • A to T, chromosome 4 at 143,812,808 bp
  • T to C, chromosome 4 at 148,029,392 bp
  • T to C, chromosome 5 at 24,402,319 bp
  • A to G, chromosome 5 at 66,997,233 bp
  • T to A, chromosome 5 at 88,494,060 bp
  • T to A, chromosome 6 at 58,868,763 bp
  • G to T, chromosome 6 at 77,244,860 bp
  • T to G, chromosome 6 at 142,565,901 bp
  • T to A, chromosome 7 at 133,998,230 bp
  • T to C, chromosome 8 at 26,162,705 bp
  • A to T, chromosome 8 at 43,625,123 bp
  • A to T, chromosome 8 at 43,651,584 bp
  • A to G, chromosome 8 at 56,125,204 bp
  • G to A, chromosome 8 at 106,885,518 bp
  • C to T, chromosome 9 at 19,713,649 bp
  • A to G, chromosome 9 at 35,565,031 bp
  • G to A, chromosome 9 at 41,023,557 bp
  • G to A, chromosome 9 at 75,037,685 bp
  • C to T, chromosome 10 at 41,451,436 bp
  • G to T, chromosome 10 at 58,629,491 bp
  • G to A, chromosome 10 at 79,971,228 bp
  • A to T, chromosome 10 at 81,622,641 bp
  • C to A, chromosome 11 at 30,121,591 bp
  • A to T, chromosome 11 at 55,181,585 bp
  • A to G, chromosome 11 at 61,373,422 bp
  • A to G, chromosome 11 at 62,876,944 bp
  • G to T, chromosome 11 at 104,505,641 bp
  • T to A, chromosome 11 at 119,414,570 bp
  • T to C, chromosome 12 at 54,894,988 bp
  • C to A, chromosome 12 at 113,158,179 bp
  • A to T, chromosome 14 at 25,757,161 bp
  • A to T, chromosome 14 at 50,320,729 bp
  • A to C, chromosome 14 at 50,618,587 bp
  • A to G, chromosome 14 at 68,516,684 bp
  • A to T, chromosome 15 at 34,839,096 bp
  • T to A, chromosome 16 at 35,156,243 bp
  • T to C, chromosome 16 at 44,243,532 bp
  • T to C, chromosome 16 at 48,975,477 bp
  • T to C, chromosome 17 at 29,687,027 bp
  • A to T, chromosome 17 at 58,042,558 bp
  • A to T, chromosome 17 at 90,037,330 bp
  • T to A, chromosome 19 at 13,654,452 bp
  • A to T, chromosome 19 at 34,573,584 bp
  • G to A, chromosome 19 at 42,032,021 bp
  • A to G, chromosome 19 at 55,918,955 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0927 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039074-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.