Strain Name:
C57BL/6J-MtgxR0940Btlr/Mmmh
Stock Number:
039079-MU
Citation ID:
RRID:MMRRC_039079-MU
Other Names:
R0940 (G1), C57BL/6J-MtgxR0940Btlr
Major Collection:

Gene Information

Inpp5a
Name: inositol polyphosphate-5-phosphatase A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212111
HGNC: HGNC:6076
Homologene: 4045
Rtel1
Name: regulator of telomere elongation helicase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269400
Homologene: 13168
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Gmps
Name: guanine monophosphate synthetase
Synonyms: Gm9479
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229363
HGNC: HGNC:4378
Homologene: 68367
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103554
Homologene: 113742
Smc3
Name: structural maintenance of chromosomes 3
Synonyms: Cspg6, Bamacan, SmcD, Mmip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13006
HGNC: HGNC:2468
Homologene: 3974
Cul3
Name: cullin 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26554
HGNC: HGNC:2553
Homologene: 2661
Pkm
Name: pyruvate kinase, muscle
Synonyms: Pk-2, Pkm2, Pk3, Pk-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18746
VEGA: 9
HGNC: HGNC:9021
Homologene: 37650
2610021A01Rik
Name: RIKEN cDNA 2610021A01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 668572
Nomo1
Name: nodal modulator 1
Synonyms: PM5, D7Ertd156e, Nomo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 211548
Homologene: 13810
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Brca1
Name: breast cancer 1, early onset
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12189
HGNC: HGNC:1100
Homologene: 5276
Prpf3
Name: pre-mRNA processing factor 3
Synonyms: 3632413F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70767
Homologene: 3447
Slc8a2
Name: solute carrier family 8 (sodium/calcium exchanger), member 2
Synonyms: Ncx2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 110891
Homologene: 27358
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, 6530403D07Rik, D2Ertd145e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Zkscan1
Name: zinc finger with KRAB and SCAN domains 1
Synonyms: KOX18, 9230118B16Rik, 9130423L19Rik, 5930429A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74570
Homologene: 34523
Bcl7c
Name: B cell CLL/lymphoma 7C
Synonyms: C230096E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12055
HGNC: HGNC:1006
Homologene: 3498
C6
Name: complement component 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12274
HGNC: HGNC:1339
Homologene: 47
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: 9330188B09Rik, 4921513O20Rik, cI-46, LOC381026, D630001M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66725
Homologene: 18982
Hnrnpm
Name: heterogeneous nuclear ribonucleoprotein M
Synonyms: Hnrpm, 2610023M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76936
HGNC: HGNC:5046
Homologene: 4354
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101471
Homologene: 16377
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: P1-Loop, Hst6.7b, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Adgre5
Name: adhesion G protein-coupled receptor E5
Synonyms: EGF-TM7 receptor, Cd97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 26364
HGNC: HGNC:1711
Homologene: 8050
Trub1
Name: TruB pseudouridine (psi) synthase family member 1
Synonyms: 9030425C13Rik, 2610009I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72133
VEGA: 19
Homologene: 34714
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, PlexA2, 2810428A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Ackr4
Name: atypical chemokine receptor 4
Synonyms: Ccrl1, VSHK1, A630091E18Rik, PPR1, CCX-CKR, CCBP2, CCR11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 252837
HGNC: HGNC:1611
Homologene: 49474
Tgm3
Name: transglutaminase 3, E polypeptide
Synonyms: TG E, we
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21818
Homologene: 20690
Fam160a1
Name: family with sequence similarity 160, member A1
Synonyms: 9930021J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229488
Homologene: 85149
Ppp2cb
Name: protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
Synonyms: PP2Ac, D8Ertd766e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19053
HGNC: HGNC:9300
Homologene: 37889
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: Ugcgl2, 3110001A05Rik, A230065J02Rik, 1810064L21Rik, 3110027P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66435
Homologene: 56875
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Nfatc1
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Synonyms: NF-ATc, NFAT2, 2210017P03Rik, NFATc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 18018
VEGA: 18
HGNC: HGNC:7775
Homologene: 32336
Ugt2a3
Name: UDP glucuronosyltransferase 2 family, polypeptide A3
Synonyms: 2010321J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72094
Homologene: 55988
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 9430041O17Rik, 2010203O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234214
Homologene: 83295
1810064F22Rik
Name: RIKEN cDNA 1810064F22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69862
Sel1l3
Name: sel-1 suppressor of lin-12-like 3 (C. elegans)
Synonyms: 2310045A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231238
Homologene: 9054
Myh4
Name: myosin, heavy polypeptide 4, skeletal muscle
Synonyms: Minmus, MM, Myhsf, MHC2B, MyHC-IIb, Minimsc, MYH-2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17884
HGNC: HGNC:7574
Homologene: 123880
Adrb2
Name: adrenergic receptor, beta 2
Synonyms: Adrb-2, beta 2-adrenoceptor, beta 2-AR, Badm, Gpcr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11555
VEGA: 18
HGNC: HGNC:286
Homologene: 30948
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Prickle2
Name: prickle planar cell polarity protein 2
Synonyms: 6230400G14Rik, mpk2, 6720451F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243548
Homologene: 17889
Olfr1221
Name: olfactory receptor 1221
Synonyms: GA_x6K02T2Q125-50591144-50590209, MOR233-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258904
Homologene: 73987
Fggy
Name: FGGY carbohydrate kinase domain containing
Synonyms: 2310009E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75578
Homologene: 49535
Olfr392
Name: olfactory receptor 392
Synonyms: GA_x6K02T2P1NL-3966976-3966038, MOR135-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259008
Homologene: 133580
Zfp616
Name: zinc finger protein 616
Synonyms: Gm12330
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327963
Homologene: 88945
Myorg
Name: myogenesis regulating glycosidase (putative)
Synonyms: NET37, AI464131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329828
Homologene: 19853
Nipal4
Name: NIPA-like domain containing 4
Synonyms: 9530066K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 214112
Homologene: 133769
Olfr525
Name: olfactory receptor 525
Synonyms: GA_x6K02T2PBJ9-42472898-42473827, MOR251-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258958
Homologene: 138321
Dsc2
Name: desmocollin 2
Synonyms: Dsc2a, Dsc2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13506
HGNC: HGNC:3036
Homologene: 8397
E330013P04Rik
Name: RIKEN cDNA E330013P04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107376
Olfr490
Name: olfactory receptor 490
Synonyms: MOR204-17, GA_x6K02T2PBJ9-10617173-10616229
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258491
Homologene: 73955
Olfr128
Name: olfactory receptor 128
Synonyms: GA_x6K02T2PSCP-2374126-2375048, MOR218-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 383243
Homologene: 134080
Pde6b
Name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Synonyms: Pdeb, rd1, rd, rd10, r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18587
HGNC: HGNC:8786
Homologene: 237
Gnmt
Name: glycine N-methyltransferase
Synonyms: glycine N methyl transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14711
HGNC: HGNC:4415
Homologene: 7741
Vav3
Name: vav 3 oncogene
Synonyms: A530094I06Rik, Idd18.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 57257
Homologene: 38143
Fmo6
Name: flavin containing monooxygenase 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226565
Homologene: 68130
Olfr1408
Name: olfactory receptor 1408
Synonyms: MOR267-4, GA_x6K02T2R7CC-715776-716708
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258759
Homologene: 128062
Gadd45a
Name: growth arrest and DNA-damage-inducible 45 alpha
Synonyms: Ddit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13197
HGNC: HGNC:4095
Homologene: 1449
Lmcd1
Name: LIM and cysteine-rich domains 1
Synonyms: dyxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30937
HGNC: HGNC:6633
Homologene: 22823
Relb
Name: avian reticuloendotheliosis viral (v-rel) oncogene related B
Synonyms: shep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19698
HGNC: HGNC:9956
Homologene: 4747
Pabpn1l
Name: poly(A)binding protein nuclear 1-like
Synonyms: LOC382035, ePABP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382035
Homologene: 19736
Akr1c6
Name: aldo-keto reductase family 1, member C6
Synonyms: Akr1c1, Hsd17b5, estradiol 17-beta-dehydrogenase (A-specific), 3alpha-HSD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 83702
HGNC: HGNC:387
Homologene: 84695
Tpbpa
Name: trophoblast specific protein alpha
Synonyms: Tb1, 4311, Tpbp, clone 4311, Tb-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21984
VEGA: 13
Homologene: 49203
Dynlt1b
Name: dynein light chain Tctex-type 1B
Synonyms: Tctex1, Dynlt1, Tctex-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21648
VEGA: 17
Homologene: 4754
Kank3
Name: KN motif and ankyrin repeat domains 3
Synonyms: Ankrd47, D17Ertd288e, 0610013D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 80880
Homologene: 12749
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 80,322,847 bp
  • A to T, chromosome 1 at 162,926,226 bp
  • A to G, chromosome 1 at 173,130,453 bp
  • G to A, chromosome 1 at 194,800,555 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • T to A, chromosome 2 at 89,112,075 bp
  • A to G, chromosome 2 at 130,012,406 bp
  • T to C, chromosome 2 at 181,322,803 bp
  • A to G, chromosome 3 at 63,976,322 bp
  • A to G, chromosome 3 at 85,665,490 bp
  • A to G, chromosome 3 at 95,844,223 bp
  • T to A, chromosome 3 at 109,562,835 bp
  • A to G, chromosome 4 at 41,497,996 bp
  • A to G, chromosome 4 at 95,697,001 bp
  • C to T, chromosome 5 at 53,144,037 bp
  • A to G, chromosome 5 at 87,327,206 bp
  • T to A, chromosome 5 at 108,420,337 bp
  • T to C, chromosome 5 at 138,093,170 bp
  • A to G, chromosome 6 at 67,036,829 bp
  • A to G, chromosome 6 at 92,411,003 bp
  • A to G, chromosome 6 at 112,328,697 bp
  • A to G, chromosome 7 at 16,144,962 bp
  • A to T, chromosome 7 at 19,611,842 bp
  • T to G, chromosome 7 at 41,626,434 bp
  • T to C, chromosome 7 at 44,506,887 bp
  • A to G, chromosome 7 at 46,033,905 bp
  • T to C, chromosome 7 at 108,287,057 bp
  • T to A, chromosome 7 at 127,707,331 bp
  • T to C, chromosome 7 at 139,525,738 bp
  • T to C, chromosome 7 at 140,323,152 bp
  • T to C, chromosome 7 at 141,254,855 bp
  • T to C, chromosome 8 at 33,615,661 bp
  • T to C, chromosome 8 at 45,796,502 bp
  • C to T, chromosome 8 at 83,733,497 bp
  • A to G, chromosome 8 at 122,622,444 bp
  • C to T, chromosome 9 at 22,208,071 bp
  • C to T, chromosome 9 at 59,668,535 bp
  • A to G, chromosome 9 at 104,099,632 bp
  • G to A, chromosome 11 at 30,815,264 bp
  • A to G, chromosome 11 at 46,150,312 bp
  • A to T, chromosome 11 at 67,242,863 bp
  • T to C, chromosome 11 at 73,814,224 bp
  • A to T, chromosome 11 at 74,085,024 bp
  • A to T, chromosome 11 at 101,532,143 bp
  • A to G, chromosome 11 at 119,416,563 bp
  • T to A, chromosome 12 at 40,631,627 bp
  • G to A, chromosome 13 at 4,436,373 bp
  • T to C, chromosome 13 at 60,940,053 bp
  • A to T, chromosome 14 at 103,262,693 bp
  • A to G, chromosome 14 at 119,091,192 bp
  • A to T, chromosome 15 at 4,735,235 bp
  • A to T, chromosome 15 at 91,729,081 bp
  • T to C, chromosome 17 at 6,430,250 bp
  • T to A, chromosome 17 at 30,803,243 bp
  • G to A, chromosome 17 at 33,650,002 bp
  • C to T, chromosome 17 at 33,817,476 bp
  • A to G, chromosome 17 at 37,923,700 bp
  • A to G, chromosome 17 at 46,726,345 bp
  • T to G, chromosome 18 at 20,050,059 bp
  • T to C, chromosome 18 at 62,179,691 bp
  • C to T, chromosome 18 at 80,635,895 bp
  • T to A, chromosome 19 at 53,640,909 bp
  • A to G, chromosome 19 at 57,485,063 bp
  • A to G, chromosome 19 at 60,161,922 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0940 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039079-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.