Strain Name:
C57BL/6J-MtgxR0964Btlr/Mmmh
Stock Number:
039093-MU
Citation ID:
RRID:MMRRC_039093-MU
Other Names:
R0964 (G1), C57BL/6J-MtgxR0964Btlr
Major Collection:

Gene Information

Sema3c
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Synonyms: 1110036B02Rik, Semae
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20348
Homologene: 36201
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: alpha13.2, Cav3.2, T-type Cav3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Ccn1
Name: cellular communication network factor 1
Synonyms: Cyr61, CCN1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16007
HGNC: HGNC:2654
Homologene: 1194
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 208440
Homologene: 40996
Plekhm1
Name: pleckstrin homology domain containing, family M (with RUN domain) member 1
Synonyms: D330036J23Rik, AP162, B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 353047
Homologene: 8871
Srsf3
Name: serine/arginine-rich splicing factor 3
Synonyms: X16, Sfrs3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20383
Homologene: 55708
Sbno2
Name: strawberry notch 2
Synonyms: Stno
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216161
VEGA: 10
Homologene: 8981
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, 1810014J18Rik, AD013, A330063D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109151
Homologene: 11844
Nckap1
Name: NCK-associated protein 1
Synonyms: Hem-2, Nap1, H19, Hem2, mh19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50884
HGNC: HGNC:7666
Homologene: 8384
Uhrf1bp1
Name: UHRF1 (ICBP90) binding protein 1
Synonyms: F830021D11Rik, 1110020K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224648
Homologene: 9816
Rps15a
Name: ribosomal protein S15A
Synonyms: A630031B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 267019
Homologene: 128982
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE-1, A330049M09Rik, enaptin165, C130039F11Rik, nesprin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 64009
VEGA: 10
Homologene: 52329
Gpbp1l1
Name: GC-rich promoter binding protein 1-like 1
Synonyms: 5330440M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77110
Homologene: 84840
Ccser2
Name: coiled-coil serine rich 2
Synonyms: Gcap14, 1700012P13Rik, 2900054P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 72972
Homologene: 10367
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: 2900070I05Rik, Lphn1, lectomedin-2, Lec2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 330814
Homologene: 8951
Uba6
Name: ubiquitin-like modifier activating enzyme 6
Synonyms: 5730469D23Rik, Ube1l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231380
Homologene: 10080
Lmo7
Name: LIM domain only 7
Synonyms: FBXO20, LOC380928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Trmt1
Name: tRNA methyltransferase 1
Synonyms: D8Ertd812e, 6720406L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 212528
Homologene: 5632
Ddx24
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
Synonyms: 1700055J08Rik, 2510027P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 27225
VEGA: 12
Homologene: 10702
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Bbs4
Name: Bardet-Biedl syndrome 4 (human)
Synonyms: D9Ertd464e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102774
VEGA: 9
HGNC: HGNC:969
Homologene: 13197
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: Mlr, aldosterone receptor, mineralocorticoid receptor, MR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: MyHC-eo, extraocular myosin, EO Myosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
9230112E08Rik
Name: RIKEN cDNA 9230112E08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Zbtb41
Name: zinc finger and BTB domain containing 41
Synonyms: 8430415N23Rik, 9830132G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226470
Homologene: 27795
Gckr
Name: glucokinase regulatory protein
Synonyms: GKRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231103
HGNC: HGNC:4196
Homologene: 1139
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 4632412F08Rik, 5330435L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237979
Homologene: 10406
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Spaca6
Name: sperm acrosome associated 6
Synonyms: Ncrna00085, B230206P06Rik, 4930546H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75202
Homologene: 53443
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 211223
Homologene: 129606
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: myosin heavy chain 2X, IId, IId/x, Myhsf2, Myhs-f, Myhs-f2, MyHC-IId/x, A530084A17Rik, MYHC-IIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Nxpe5
Name: neurexophilin and PC-esterase domain family, member 5
Synonyms: Fam55 related, BC055004
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381680
Homologene: 134143
Slc36a1
Name: solute carrier family 36 (proton/amino acid symporter), member 1
Synonyms: 5830411H19Rik, Pat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215335
Homologene: 121860
Acpp
Name: acid phosphatase, prostate
Synonyms: PAP, A030005E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56318
HGNC: HGNC:125
Homologene: 55552
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329421
Homologene: 51393
Pitpnm3
Name: PITPNM family member 3
Synonyms: Ackr6, A330068P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 327958
Homologene: 66271
Alppl2
Name: alkaline phosphatase, placental-like 2
Synonyms: D1Ertd816e, Akp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11650
Homologene: 129600
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC380729, Gm1564, LOC268491
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268491
Homologene: 19559
Atp8b4
Name: ATPase, class I, type 8B, member 4
Synonyms: Im
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241633
Homologene: 133162
Zfp938
Name: zinc finger protein 938
Synonyms: B230315N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237411
Homologene: 135924
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224576
Homologene: 135824
Olfr67
Name: olfactory receptor 67
Synonyms: MOR31-1, GA_x6K02T2PBJ9-6515150-6514170, 3'[b]1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18368
Homologene: 85930
Olfr1008
Name: olfactory receptor 1008
Synonyms: MOR187-3, GA_x6K02T2Q125-47170431-47171372
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258866
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243944
Homologene: 77912
Prdm11
Name: PR domain containing 11
Synonyms: 8030443D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 100042784
Homologene: 82511
Zbtb39
Name: zinc finger and BTB domain containing 39
Synonyms: 7030401O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 320080
VEGA: 10
Homologene: 8890
Apol8
Name: apolipoprotein L 8
Synonyms: 9830006J20Rik, Apol2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239552
VEGA: 15
HGNC: HGNC:619
Homologene: 12785
Prodh2
Name: proline dehydrogenase (oxidase) 2
Synonyms: POX1, MmPOX1, 2510038B11Rik, 2510028N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56189
Homologene: 36381
Creg2
Name: cellular repressor of E1A-stimulated genes 2
Synonyms: A830098L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 263764
Homologene: 17827
Olfr460
Name: olfactory receptor 460
Synonyms: MOR120-2, GA_x6K02T2P3E9-6947292-6946348
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 258381
Homologene: 64866
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 39,624,976 bp
  • C to T, chromosome 1 at 87,087,724 bp
  • T to G, chromosome 1 at 139,439,031 bp
  • A to G, chromosome 2 at 31,391,511 bp
  • A to C, chromosome 2 at 70,426,849 bp
  • A to G, chromosome 2 at 80,547,899 bp
  • A to G, chromosome 2 at 85,690,365 bp
  • C to A, chromosome 2 at 92,989,222 bp
  • A to T, chromosome 2 at 126,337,493 bp
  • T to A, chromosome 2 at 180,984,485 bp
  • A to G, chromosome 3 at 144,915,576 bp
  • C to A, chromosome 3 at 145,647,748 bp
  • A to G, chromosome 4 at 116,581,239 bp
  • T to C, chromosome 5 at 17,721,909 bp
  • T to C, chromosome 5 at 31,326,915 bp
  • T to C, chromosome 5 at 86,119,401 bp
  • T to C, chromosome 5 at 109,297,535 bp
  • A to T, chromosome 5 at 114,229,752 bp
  • T to C, chromosome 5 at 138,239,924 bp
  • T to C, chromosome 6 at 40,572,205 bp
  • C to A, chromosome 7 at 30,506,281 bp
  • A to T, chromosome 7 at 40,993,056 bp
  • C to T, chromosome 7 at 103,787,397 bp
  • T to C, chromosome 7 at 118,114,837 bp
  • T to C, chromosome 7 at 119,952,739 bp
  • A to G, chromosome 8 at 76,908,668 bp
  • T to C, chromosome 8 at 83,934,412 bp
  • T to A, chromosome 8 at 84,696,852 bp
  • A to G, chromosome 8 at 91,015,204 bp
  • A to G, chromosome 9 at 59,322,976 bp
  • A to G, chromosome 9 at 104,326,975 bp
  • T to C, chromosome 10 at 5,043,652 bp
  • G to T, chromosome 10 at 80,084,259 bp
  • T to A, chromosome 10 at 82,225,419 bp
  • C to G, chromosome 10 at 127,742,306 bp
  • A to G, chromosome 11 at 55,225,954 bp
  • A to G, chromosome 11 at 67,205,925 bp
  • A to G, chromosome 11 at 67,221,604 bp
  • A to G, chromosome 11 at 67,345,002 bp
  • G to A, chromosome 11 at 72,058,470 bp
  • G to A, chromosome 11 at 102,680,031 bp
  • C to A, chromosome 11 at 103,395,082 bp
  • A to G, chromosome 11 at 113,806,417 bp
  • C to T, chromosome 12 at 103,423,907 bp
  • G to A, chromosome 13 at 9,568,663 bp
  • C to T, chromosome 14 at 36,909,008 bp
  • T to C, chromosome 14 at 101,920,567 bp
  • C to T, chromosome 15 at 77,749,611 bp
  • A to T, chromosome 17 at 17,838,391 bp
  • G to A, chromosome 17 at 20,267,597 bp
  • A to T, chromosome 17 at 25,378,775 bp
  • A to T, chromosome 17 at 27,887,178 bp
  • C to A, chromosome 17 at 29,036,438 bp
  • T to A, chromosome 17 at 29,036,439 bp
  • G to A, chromosome 17 at 30,673,920 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0964 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039093-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.