Strain Name:
C57BL/6J-MtgxR1015Btlr/Mmmh
Stock Number:
039119-MU
Citation ID:
RRID:MMRRC_039119-MU
Other Names:
R1015 (G1), C57BL/6J-MtgxR1015Btlr
Major Collection:

Gene Information

Pdzd2
Name: PDZ domain containing 2
Synonyms: A930022H17Rik, Pdzk3, Gm21706, 4930537L06Rik, LOC223364
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68070
Homologene: 23393
Mapkapk5
Name: MAP kinase-activated protein kinase 5
Synonyms: MK5, PRAK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17165
HGNC: HGNC:6889
Homologene: 69077
Mib1
Name: mindbomb E3 ubiquitin protein ligase 1
Synonyms: Mib, mind bomb-1, E430019M12Rik, skeletrophin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225164
Homologene: 10810
Vasp
Name: vasodilator-stimulated phosphoprotein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22323
Homologene: 7592
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382038
Homologene: 8859
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, 1810014J18Rik, AD013, A330063D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109151
Homologene: 11844
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57752
Homologene: 5087
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: Murr2, A530081C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17847
Homologene: 40978
Usp53
Name: ubiquitin specific peptidase 53
Synonyms: mbo, Phxr3, Sp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99526
Homologene: 34521
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330627
Homologene: 28044
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: mBLVR1, Bolvr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Atp6v1d
Name: ATPase, H+ transporting, lysosomal V1 subunit D
Synonyms: Vma8, lysosomal 34kDa, VATD, Atp6m, 1110004P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 73834
VEGA: 12
Homologene: 5783
Cep135
Name: centrosomal protein 135
Synonyms: Cep4, LOC381644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381644
Homologene: 45709
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Cpt1a
Name: carnitine palmitoyltransferase 1a, liver
Synonyms: L-CPT I, Cpt1, CPTI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12894
VEGA: 19
HGNC: HGNC:2328
Homologene: 1413
Cep120
Name: centrosomal protein 120
Synonyms: Ccdc100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225523
VEGA: 18
Homologene: 27415
Map3k14
Name: mitogen-activated protein kinase kinase kinase 14
Synonyms: Nik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 53859
HGNC: HGNC:6853
Homologene: 2940
Nfix
Name: nuclear factor I/X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18032
HGNC: HGNC:7788
Homologene: 1872
Slc3a2
Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Synonyms: Mdu1, Mgp-2hc, Cd98, 4F2HC, Ly-m10, Ly-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 17254
Homologene: 1795
Snx9
Name: sorting nexin 9
Synonyms: SDP1, SH3PX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66616
VEGA: 17
Homologene: 49454
Ola1
Name: Obg-like ATPase 1
Synonyms: 2810409H07Rik, 2510025G09Rik, 2810405J23Rik, Gtpbp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67059
Homologene: 5361
Lmbrd1
Name: LMBR1 domain containing 1
Synonyms: 0910001K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68421
Homologene: 10156
Patl1
Name: protein associated with topoisomerase II homolog 1 (yeast)
Synonyms: Pat1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225929
VEGA: 19
Homologene: 82269
Taf4b
Name: TATA-box binding protein associated factor 4b
Synonyms: 105kDa, 2610524B04Rik, TAFII105, Taf2c2, 4932409F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 72504
VEGA: 18
Homologene: 28266
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217351
Homologene: 23137
C8b
Name: complement component 8, beta polypeptide
Synonyms: 4930439B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 110382
HGNC: HGNC:1353
Homologene: 48
Myo16
Name: myosin XVI
Synonyms: BM140241, C230040D10Rik, Nyap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244281
Homologene: 34710
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75050
VEGA: 13
Homologene: 69235
Galnt2
Name: polypeptide N-acetylgalactosaminyltransferase 2
Synonyms: ppGaNTase-T2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 108148
HGNC: HGNC:4124
Homologene: 3297
Kdm5d
Name: lysine (K)-specific demethylase 5D
Synonyms: Jarid1d, Smcy, HY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 20592
Homologene: 55838
Fbxw18
Name: F-box and WD-40 domain protein 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 546161
Homologene: 110776
Mcc
Name: mutated in colorectal cancers
Synonyms: D18Ertd451e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 328949
HGNC: HGNC:6935
Homologene: 20539
Snapc4
Name: small nuclear RNA activating complex, polypeptide 4
Synonyms: 5730436L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227644
Homologene: 2321
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268933
Homologene: 6870
Eps8l1
Name: EPS8-like 1
Synonyms: 4632407K17Rik, EPS8R1, 2310051G19Rik, DRC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67425
Homologene: 15767
Kif5c
Name: kinesin family member 5C
Synonyms: Khc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16574
HGNC: HGNC:6325
Homologene: 56234
Slc44a5
Name: solute carrier family 44, member 5
Synonyms: LOC242259
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242259
Homologene: 72094
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380730
Homologene: 134511
Auh
Name: AU RNA binding protein/enoyl-coenzyme A hydratase
Synonyms: W91705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 11992
HGNC: HGNC:890
Homologene: 1284
Rspo1
Name: R-spondin 1
Synonyms: R-spondin, Rspondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 192199
Homologene: 52148
Krt18
Name: keratin 18
Synonyms: Krt1-18, K18, CK18, Endo B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16668
VEGA: 15
HGNC: HGNC:6430
Homologene: 55448
Ndst2
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
Synonyms: [Heparan sulfate]-glucosamine N-sulfotransferase, Mndns, glucosaminyl N-deacetylase/N-sulphotransferase-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 17423
VEGA: 14
HGNC: HGNC:7681
Homologene: 20803
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: flamingo, Fmi1, Adgrc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: B830017A01Rik, 3110047P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319807
Homologene: 14974
Ces1e
Name: carboxylesterase 1E
Synonyms: egasyn, Es-22, Eg, Es22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13897
HGNC: HGNC:1863
Homologene: 115660
Gm5499
Name: predicted pseudogene 5499
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 433144
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244418
Homologene: 18256
Gm8765
Name: predicted gene 8765
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 667693
Homologene: 134512
Ccdc85a
Name: coiled-coil domain containing 85A
Synonyms: E030025D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216613
Homologene: 65605
Olfr1034
Name: olfactory receptor 1034
Synonyms: MOR227-8P, Olfr1533-ps1, GA_x6K02T2Q125-47521463-47522395, MOR227-8P, MOR245-14P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258216
Homologene: 51741
Cage1
Name: cancer antigen 1
Synonyms: 4933427I01Rik, Ctag3, CAGE1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 71213
Homologene: 18484
Ces2f
Name: carboxylesterase 2F
Synonyms: 2310038E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71903
HGNC: HGNC:1864
Homologene: 135673
B3gnt6
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
Synonyms: Core-3, Core3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 272411
Homologene: 16339
Gm8214
Name: predicted gene 8214
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Olfr74
Name: olfactory receptor 74
Synonyms: GA_x6K02T2Q125-49458388-49457432, mOR-EV, MOR174-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 117005
Homologene: 74078
Pla2g2f
Name: phospholipase A2, group IIF
Synonyms: mGIIFsPLA2s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 26971
Homologene: 8084
AU022751
Name: expressed sequence AU022751
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 102991
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 24,731,878 bp
  • A to T, chromosome 1 at 153,166,199 bp
  • A to T, chromosome 1 at 183,682,160 bp
  • A to T, chromosome 2 at 26,378,077 bp
  • T to A, chromosome 2 at 49,744,365 bp
  • A to G, chromosome 2 at 73,203,312 bp
  • T to C, chromosome 2 at 86,047,082 bp
  • T to C, chromosome 2 at 87,974,087 bp
  • A to G, chromosome 3 at 122,933,759 bp
  • T to A, chromosome 3 at 154,256,600 bp
  • A to G, chromosome 4 at 104,786,960 bp
  • C to A, chromosome 4 at 124,991,434 bp
  • C to T, chromosome 4 at 138,754,268 bp
  • T to C, chromosome 5 at 63,806,811 bp
  • T to C, chromosome 5 at 76,640,997 bp
  • T to C, chromosome 5 at 121,533,362 bp
  • A to T, chromosome 7 at 4,469,933 bp
  • A to T, chromosome 7 at 19,259,223 bp
  • C to A, chromosome 7 at 98,194,595 bp
  • C to T, chromosome 7 at 109,455,233 bp
  • A to G, chromosome 7 at 130,624,065 bp
  • A to G, chromosome 8 at 10,390,183 bp
  • T to C, chromosome 8 at 36,146,543 bp
  • G to A, chromosome 8 at 84,726,526 bp
  • T to A, chromosome 8 at 90,932,578 bp
  • A to G, chromosome 8 at 93,229,364 bp
  • A to G, chromosome 8 at 104,952,628 bp
  • T to C, chromosome 8 at 124,029,434 bp
  • C to T, chromosome 8 at 124,336,617 bp
  • G to A, chromosome 9 at 54,367,765 bp
  • T to C, chromosome 9 at 108,833,176 bp
  • T to C, chromosome 9 at 109,702,545 bp
  • A to G, chromosome 10 at 80,716,489 bp
  • T to C, chromosome 11 at 23,468,790 bp
  • T to C, chromosome 11 at 28,399,365 bp
  • T to A, chromosome 11 at 103,225,300 bp
  • T to C, chromosome 11 at 103,545,796 bp
  • C to T, chromosome 11 at 117,721,922 bp
  • A to G, chromosome 12 at 78,849,769 bp
  • T to A, chromosome 13 at 38,016,475 bp
  • T to G, chromosome 13 at 50,701,628 bp
  • C to A, chromosome 13 at 52,909,330 bp
  • T to A, chromosome 13 at 58,320,215 bp
  • T to C, chromosome 14 at 20,730,064 bp
  • T to C, chromosome 15 at 12,374,508 bp
  • T to C, chromosome 15 at 102,031,300 bp
  • A to G, chromosome 17 at 5,920,127 bp
  • A to G, chromosome 17 at 25,828,238 bp
  • A to G, chromosome 17 at 87,078,695 bp
  • T to A, chromosome 18 at 10,726,409 bp
  • T to A, chromosome 18 at 14,813,098 bp
  • C to A, chromosome 18 at 44,724,669 bp
  • C to T, chromosome 18 at 53,703,121 bp
  • T to A, chromosome 19 at 3,369,058 bp
  • C to T, chromosome 19 at 8,707,955 bp
  • T to C, chromosome 19 at 11,920,373 bp
  • GTCATCATCATCATC to GTCATCATCATCATCATC, chromosome X at 6,082,591 bp
  • T to C, chromosome Y at 941,687 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1015 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039119-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.