Strain Name:
C57BL/6J-MtgxR1037Btlr/Mmmh
Stock Number:
039136-MU
Citation ID:
RRID:MMRRC_039136-MU
Other Names:
R1037 (G1), C57BL/6J-MtgxR1037Btlr
Major Collection:

Gene Information

Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11287
Homologene: 104112
Slc17a6
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
Synonyms: 2900073D12Rik, VGLUT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 140919
Homologene: 121617
Swt1
Name: SWT1 RNA endoribonuclease homolog (S. cerevisiae)
Synonyms: 1200016B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66875
Homologene: 32355
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 4930432B04Rik, 3110043H24Rik, D730027C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75786
Homologene: 8844
Trim36
Name: tripartite motif-containing 36
Synonyms: D18Wsu100e, Haprin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 28105
VEGA: 18
Homologene: 10275
Sbno1
Name: strawberry notch 1
Synonyms: 9330180L10Rik, sno
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243272
Homologene: 10055
Clasp2
Name: CLIP associating protein 2
Synonyms: 8030404L10Rik, CLASP2, CLASP2gamma, CLASP2alpha, CLASP2beta, 1500004F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Cep57
Name: centrosomal protein 57
Synonyms: 4921510P06Rik, 4931428M20Rik, Tsp57, 3110002L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74360
Homologene: 8790
Dbnl
Name: drebrin-like
Synonyms: mAbp1, ABP1, SH3P7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13169
HGNC: HGNC:2696
Homologene: 8468
Fasn
Name: fatty acid synthase
Synonyms: A630082H08Rik, FAS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Cacnb1
Name: calcium channel, voltage-dependent, beta 1 subunit
Synonyms: Cchlb1, Cchb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12295
HGNC: HGNC:1401
Homologene: 20186
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: Zzank1, 2210008I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76580
Homologene: 16062
Thbs1
Name: thrombospondin 1
Synonyms: TSP1, TSP-1, Thbs-1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21825
Homologene: 31142
Ttc1
Name: tetratricopeptide repeat domain 1
Synonyms: TPR1, 4833412C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66827
Homologene: 2485
Exosc8
Name: exosome component 8
Synonyms: 2310032N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69639
Homologene: 12323
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: l7Rn3, Ten-m4, ELM2, Doc4, Odz4, l(7)-3Rn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23966
Homologene: 8034
Fam72a
Name: family with sequence similarity 72, member A
Synonyms: 2700049P18Rik, P17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108900
Homologene: 82352
Nup160
Name: nucleoporin 160
Synonyms: 2810011M03Rik, Gtl1-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59015
Homologene: 32509
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99003
Homologene: 11710
Lrrc4c
Name: leucine rich repeat containing 4C
Synonyms: netrin g1 ligand, 6430556C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241568
Homologene: 18696
Grn
Name: granulin
Synonyms: progranulin, acrogranulin, PC cell-derived growth factor, Pgrn, epithelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14824
HGNC: HGNC:4601
Homologene: 1577
Septin5
Name: septin 5
Synonyms: Sept5, Pnutl1, Cdcrel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 18951
VEGA: 16
HGNC: HGNC:9164
Homologene: 74446
Uckl1
Name: uridine-cytidine kinase 1-like 1
Synonyms: 1110007H10Rik, Urkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68556
Homologene: 101414
Gsap
Name: gamma-secretase activating protein
Synonyms: Pion, A530088I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 212167
Homologene: 45504
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Olfr201
Name: olfactory receptor 201
Synonyms: MOR182-2, GA_x54KRFPKG5P-55483936-55483010
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258996
Homologene: 37011
Abcb1b
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Synonyms: Pgy1, Mdr1, Abcb1, mdr, Pgy-1, Mdr1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18669
Homologene: 69084
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: bl, E130113P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231470
Homologene: 23516
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 1110004P15Rik, 2310047C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
4933405L10Rik
Name: RIKEN cDNA 4933405L10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71046
Homologene: 19274
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74362
Homologene: 52601
Col11a1
Name: collagen, type XI, alpha 1
Synonyms: C530001D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12814
HGNC: HGNC:2186
Homologene: 56389
Abca2
Name: ATP-binding cassette, sub-family A (ABC1), member 2
Synonyms: D2H0S1474E, Abc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Olfr177
Name: olfactory receptor 177
Synonyms: MOR184-7, GA_x54KRFPKG5P-55091371-55090442
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258998
Homologene: 121500
Tor1aip2
Name: torsin A interacting protein 2
Synonyms: 1110020D10Rik, Ifrg15, LULL1, 15kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240832
Homologene: 17028
Prl2c5
Name: prolactin family 2, subfamily c, member 5
Synonyms: MRP-4, PLF-4, Mrpplf4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 107849
Homologene: 40763
Palm3
Name: paralemmin 3
Synonyms: 4432412L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74337
Homologene: 53493
Olfr1197
Name: olfactory receptor 1197
Synonyms: MOR225-10P, MOR225-14, GA_x6K02T2Q125-50202854-50201910
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 433449
Homologene: 123770
Cyp24a1
Name: cytochrome P450, family 24, subfamily a, polypeptide 1
Synonyms: Cyp24, 24-OHase, CP24, 25-hydroxyvitamin D-24-hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13081
HGNC: HGNC:2602
Homologene: 68094
Itgb6
Name: integrin beta 6
Synonyms: 4831415H04Rik, 2210409C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16420
HGNC: HGNC:6161
Homologene: 685
Opcml
Name: opioid binding protein/cell adhesion molecule-like
Synonyms: B930023M13Rik, LOC235104, 2900075O15Rik, Obcam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330908
HGNC: HGNC:8143
Homologene: 55663
Tmprss11g
Name: transmembrane protease, serine 11g
Synonyms: Desc4, 9930032O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320454
Homologene: 82239
Hook3
Name: hook microtubule tethering protein 3
Synonyms: E330005F07Rik, 5830454D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320191
Homologene: 13022
Olfr516
Name: olfactory receptor 516
Synonyms: GA_x6K02T2PBJ9-11176324-11175380, MOR268-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258720
HGNC: HGNC:8162
Homologene: 138316
Kmo
Name: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98256
HGNC: HGNC:6381
Homologene: 2729
Mmp21
Name: matrix metallopeptidase 21
Synonyms: b2b873Clo, b2b2458Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 214766
Homologene: 17519
Mlc1
Name: megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Synonyms: Kiaa0027-hp, WKL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170790
Homologene: 15775
Eepd1
Name: endonuclease/exonuclease/phosphatase family domain containing 1
Synonyms: 2310005P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67484
Homologene: 12144
CAAA01083517.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Olfr1166
Name: olfactory receptor 1166
Synonyms: MOR174-6, GA_x6K02T2Q125-49616865-49615915
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258644
Homologene: 138307
Cyp4a14
Name: cytochrome P450, family 4, subfamily a, polypeptide 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13119
Homologene: 134697
H2bc15
Name: H2B clustered histone 15
Synonyms: Hist1h2bn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319187
HGNC: HGNC:4750
Homologene: 136772
Tmem191c
Name: transmembrane protein 191C
Synonyms: D16Bwg1494e, 4933405M22Rik, MNCb-4137
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224019
Homologene: 131221
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 131,533,819 bp
  • A to T, chromosome 1 at 151,370,569 bp
  • A to G, chromosome 1 at 156,065,336 bp
  • C to T, chromosome 1 at 175,651,618 bp
  • T to C, chromosome 1 at 183,357,354 bp
  • T to A, chromosome 2 at 25,438,228 bp
  • T to C, chromosome 2 at 60,650,068 bp
  • A to G, chromosome 2 at 88,124,229 bp
  • T to A, chromosome 2 at 88,729,032 bp
  • C to T, chromosome 2 at 90,693,902 bp
  • T to C, chromosome 2 at 91,550,629 bp
  • A to G, chromosome 2 at 97,629,985 bp
  • T to C, chromosome 2 at 104,760,555 bp
  • A to G, chromosome 2 at 112,869,108 bp
  • A to T, chromosome 2 at 118,123,051 bp
  • G to A, chromosome 2 at 170,491,617 bp
  • C to T, chromosome 2 at 181,572,485 bp
  • G to T, chromosome 3 at 54,732,738 bp
  • A to T, chromosome 3 at 100,103,117 bp
  • A to C, chromosome 3 at 114,194,152 bp
  • A to C, chromosome 4 at 115,489,996 bp
  • C to T, chromosome 4 at 155,659,460 bp
  • A to T, chromosome 5 at 8,825,657 bp
  • A to G, chromosome 5 at 21,251,165 bp
  • A to T, chromosome 5 at 86,490,747 bp
  • C to T, chromosome 5 at 96,714,463 bp
  • A to G, chromosome 5 at 124,393,912 bp
  • T to C, chromosome 6 at 128,519,426 bp
  • A to G, chromosome 7 at 51,649,248 bp
  • T to C, chromosome 7 at 96,797,481 bp
  • T to A, chromosome 7 at 108,845,984 bp
  • T to C, chromosome 7 at 133,674,453 bp
  • T to C, chromosome 8 at 26,072,350 bp
  • C to A, chromosome 8 at 84,029,272 bp
  • A to G, chromosome 8 at 105,709,512 bp
  • T to C, chromosome 9 at 13,818,979 bp
  • T to C, chromosome 9 at 25,586,783 bp
  • T to A, chromosome 9 at 28,903,299 bp
  • T to C, chromosome 9 at 113,896,634 bp
  • T to C, chromosome 11 at 5,796,807 bp
  • A to G, chromosome 11 at 43,730,499 bp
  • T to C, chromosome 11 at 98,005,017 bp
  • C to A, chromosome 11 at 102,433,070 bp
  • C to T, chromosome 11 at 120,809,451 bp
  • T to A, chromosome 13 at 13,185,907 bp
  • T to A, chromosome 13 at 21,754,247 bp
  • C to A, chromosome 14 at 79,086,654 bp
  • A to G, chromosome 15 at 88,965,461 bp
  • A to G, chromosome 16 at 17,276,483 bp
  • G to A, chromosome 16 at 18,623,094 bp
  • T to C, chromosome 16 at 58,872,970 bp
  • C to T, chromosome 16 at 59,268,944 bp
  • A to G, chromosome 18 at 46,196,318 bp
  • T to C, chromosome 19 at 9,007,618 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1037 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039136-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.