Strain Name:
C57BL/6J-MtgxR1037Btlr/Mmmh
Stock Number:
039136-MU
Citation ID:
RRID:MMRRC_039136-MU
Other Names:
R1037 (G1), C57BL/6J-MtgxR1037Btlr
Major Collection:

Strain Information

Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11287
Homologene: 104112
Slc17a6
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
Synonyms: VGLUT2, 2900073D12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 140919
Homologene: 121617
Swt1
Name: SWT1 RNA endoribonuclease homolog (S. cerevisiae)
Synonyms: 1200016B10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66875
Homologene: 32355
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 3110043H24Rik, D730027C18Rik, 4930432B04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75786
Homologene: 8844
Trim36
Name: tripartite motif-containing 36
Synonyms: Haprin, D18Wsu100e
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 28105
VEGA: 18
Homologene: 10275
Sbno1
Name: strawberry notch 1
Synonyms: sno, 9330180L10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243272
Homologene: 10055
Clasp2
Name: CLIP associating protein 2
Synonyms: 8030404L10Rik, CLASP2gamma, CLASP2beta, CLASP2, 1500004F14Rik, CLASP2alpha
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Cep57
Name: centrosomal protein 57
Synonyms: 4931428M20Rik, 4921510P06Rik, 3110002L15Rik, Tsp57
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74360
Homologene: 8790
Dbnl
Name: drebrin-like
Synonyms: mAbp1, SH3P7, ABP1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13169
HGNC: HGNC:2696
Homologene: 8468
Fasn
Name: fatty acid synthase
Synonyms: A630082H08Rik, FAS
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Cacnb1
Name: calcium channel, voltage-dependent, beta 1 subunit
Synonyms: Cchb1, Cchlb1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12295
HGNC: HGNC:1401
Homologene: 20186
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: Zzank1, 2210008I11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76580
Homologene: 16062
Thbs1
Name: thrombospondin 1
Synonyms: TSP1, tbsp1, TSP-1, Thbs-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21825
Homologene: 31142
Ttc1
Name: tetratricopeptide repeat domain 1
Synonyms: 4833412C19Rik, TPR1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66827
Homologene: 2485
Exosc8
Name: exosome component 8
Synonyms: 2310032N20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69639
Homologene: 12323
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: Ten-m4, l7Rn3, Odz4, l(7)-3Rn, ELM2, Doc4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23966
Homologene: 8034
Fam72a
Name: family with sequence similarity 72, member A
Synonyms: 2700049P18Rik, P17
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108900
Homologene: 82352
Nup160
Name: nucleoporin 160
Synonyms: 2810011M03Rik, Gtl1-13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 59015
Homologene: 32509
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99003
Homologene: 11710
Lrrc4c
Name: leucine rich repeat containing 4C
Synonyms: 6430556C10Rik, netrin g1 ligand, NGL-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241568
Homologene: 18696
Grn
Name: granulin
Synonyms: epithelin, acrogranulin, PC cell-derived growth factor, Pgrn, progranulin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14824
HGNC: HGNC:4601
Homologene: 1577
Septin5
Name: septin 5
Synonyms: Sept5, Pnutl1, Cdcrel1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 18951
VEGA: 16
HGNC: HGNC:9164
Homologene: 74446
Uckl1
Name: uridine-cytidine kinase 1-like 1
Synonyms: Urkl1, 1110007H10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68556
Homologene: 101414
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212167
Homologene: 45504
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
Or5ac19
Name: olfactory receptor family 5 subfamily AC member 19
Synonyms: GA_x54KRFPKG5P-55483936-55483010, MOR182-2, Olfr201
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258996
Homologene: 37011
Abcb1b
Name: ATP-binding cassette, sub-family B member 1B
Synonyms: mdr, Mdr1b, Mdr1, Pgy-1, Abcb1, Pgy1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18669
HGNC: HGNC:40
Homologene: 69084
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231470
Homologene: 23516
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 1300010F03Rik, 4932416F07Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 1110004P15Rik, 2310047C17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
4933405L10Rik
Name: RIKEN cDNA 4933405L10 gene
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71046
Homologene: 19274
Spag17
Name: sperm associated antigen 17
Synonyms: PF6, 4931427F14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74362
Homologene: 52601
Col11a1
Name: collagen, type XI, alpha 1
Synonyms: C530001D20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12814
HGNC: HGNC:2186
Homologene: 56389
Abca2
Name: ATP-binding cassette, sub-family A member 2
Synonyms: Abc2, D2H0S1474E
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Or5k14
Name: olfactory receptor family 5 subfamily K member 14
Synonyms: GA_x54KRFPKG5P-55043245-55042289, MOR184-8, MOR184-7, GA_x54KRFPKG5P-55091371-55090442, Olfr176, Olfr177
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258998
Homologene: 121500
Tor1aip2
Name: torsin A interacting protein 2
Synonyms: LULL1, 15kDa, 1110020D10Rik, Ifrg15
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240832
Homologene: 17028
Prl2c5
Name: prolactin family 2, subfamily c, member 5
Synonyms: MRP-4, Mrpplf4, PLF-4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107849
Homologene: 40763
Palm3
Name: paralemmin 3
Synonyms: 4432412L15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74337
Homologene: 53493
Or4a27
Name: olfactory receptor family 4 subfamily A member 27
Synonyms: Olfr1197, MOR225-14, MOR225-10P, GA_x6K02T2Q125-50202854-50201910
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 433449
Homologene: 123770
Cyp24a1
Name: cytochrome P450, family 24, subfamily a, polypeptide 1
Synonyms: 24-OHase, Cyp24, CP24, 25-hydroxyvitamin D-24-hydroxylase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13081
HGNC: HGNC:2602
Homologene: 68094
Itgb6
Name: integrin beta 6
Synonyms: 4831415H04Rik, 2210409C20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16420
HGNC: HGNC:6161
Homologene: 685
Opcml
Name: opioid binding protein/cell adhesion molecule-like
Synonyms: 2900075O15Rik, Obcam, LOC235104, B930023M13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330908
HGNC: HGNC:8143
Homologene: 55663
Tmprss11g
Name: transmembrane protease, serine 11g
Synonyms: Desc4, 9930032O22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320454
Homologene: 82239
Hook3
Name: hook microtubule tethering protein 3
Synonyms: 5830454D03Rik, E330005F07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320191
Homologene: 13022
Or10a3b
Name: olfactory receptor family 10 subfamily A member 3B
Synonyms: GA_x6K02T2PBJ9-11176324-11175380, Olfr516, MOR268-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258720
Homologene: 138316
Kmo
Name: kynurenine 3-monooxygenase
Synonyms: kynurenine 3-hydroxylase
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98256
HGNC: HGNC:6381
Homologene: 2729
Mmp21
Name: matrix metallopeptidase 21
Synonyms: b2b2458Clo, b2b873Clo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 214766
Homologene: 17519
Mlc1
Name: megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Synonyms: WKL1, Kiaa0027-hp
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170790
Homologene: 15775
Eepd1
Name: endonuclease/exonuclease/phosphatase family domain containing 1
Synonyms: 2310005P05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67484
Homologene: 12144
CAAA01083517.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Or5d38
Name: olfactory receptor family 5 subfamily D member 38
Synonyms: GA_x6K02T2Q125-49616865-49615915, Olfr1166, MOR174-6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258644
Homologene: 138307
Cyp4a14
Name: cytochrome P450, family 4, subfamily a, polypeptide 14
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13119
Homologene: 134697
H2bc15
Name: H2B clustered histone 15
Synonyms: Hist1h2bn
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319187
Homologene: 136772
Tmem191
Name: transmembrane protein 191
Synonyms: 4933405M22Rik, D16Bwg1494e, Tmem191c, MNCb-4137
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224019
Homologene: 131221
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 131,533,819 bp
  • A to T, chromosome 1 at 151,370,569 bp
  • A to G, chromosome 1 at 156,065,336 bp
  • C to T, chromosome 1 at 175,651,618 bp
  • T to C, chromosome 1 at 183,357,354 bp
  • T to A, chromosome 2 at 25,438,228 bp
  • T to C, chromosome 2 at 60,650,068 bp
  • A to G, chromosome 2 at 88,124,229 bp
  • T to A, chromosome 2 at 88,729,032 bp
  • C to T, chromosome 2 at 90,693,902 bp
  • T to C, chromosome 2 at 91,550,629 bp
  • A to G, chromosome 2 at 97,629,985 bp
  • T to C, chromosome 2 at 104,760,555 bp
  • A to G, chromosome 2 at 112,869,108 bp
  • A to T, chromosome 2 at 118,123,051 bp
  • G to A, chromosome 2 at 170,491,617 bp
  • C to T, chromosome 2 at 181,572,485 bp
  • G to T, chromosome 3 at 54,732,738 bp
  • A to T, chromosome 3 at 100,103,117 bp
  • A to C, chromosome 3 at 114,194,152 bp
  • A to C, chromosome 4 at 115,489,996 bp
  • C to T, chromosome 4 at 155,659,460 bp
  • A to T, chromosome 5 at 8,825,657 bp
  • A to G, chromosome 5 at 21,251,165 bp
  • A to T, chromosome 5 at 86,490,747 bp
  • C to T, chromosome 5 at 96,714,463 bp
  • A to G, chromosome 5 at 124,393,912 bp
  • T to C, chromosome 6 at 128,519,426 bp
  • A to G, chromosome 7 at 51,649,248 bp
  • T to C, chromosome 7 at 96,797,481 bp
  • T to A, chromosome 7 at 108,845,984 bp
  • T to C, chromosome 7 at 133,674,453 bp
  • T to C, chromosome 8 at 26,072,350 bp
  • C to A, chromosome 8 at 84,029,272 bp
  • A to G, chromosome 8 at 105,709,512 bp
  • T to C, chromosome 9 at 13,818,979 bp
  • T to C, chromosome 9 at 25,586,783 bp
  • T to A, chromosome 9 at 28,903,299 bp
  • T to C, chromosome 9 at 113,896,634 bp
  • T to C, chromosome 11 at 5,796,807 bp
  • A to G, chromosome 11 at 43,730,499 bp
  • T to C, chromosome 11 at 98,005,017 bp
  • C to A, chromosome 11 at 102,433,070 bp
  • C to T, chromosome 11 at 120,809,451 bp
  • T to A, chromosome 13 at 13,185,907 bp
  • T to A, chromosome 13 at 21,754,247 bp
  • C to A, chromosome 14 at 79,086,654 bp
  • A to G, chromosome 15 at 88,965,461 bp
  • A to G, chromosome 16 at 17,276,483 bp
  • G to A, chromosome 16 at 18,623,094 bp
  • T to C, chromosome 16 at 58,872,970 bp
  • C to T, chromosome 16 at 59,268,944 bp
  • A to G, chromosome 18 at 46,196,318 bp
  • T to C, chromosome 19 at 9,007,618 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1037 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039136-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.