Strain Name:
C57BL/6J-MtgxR1079Btlr/Mmmh
Stock Number:
039165-MU
Citation ID:
RRID:MMRRC_039165-MU
Other Names:
R1079 (G1), C57BL/6J-MtgxR1079Btlr
Major Collection:

Gene Information

Kif3a
Name: kinesin family member 3A
Synonyms: Kif3, Kns3, kinesin-II subunit, N-4 kinesin, Kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16568
HGNC: HGNC:6319
Homologene: 38266
Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20349
Homologene: 8247
Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Gtf2i
Name: general transcription factor II I
Synonyms: 6030441I21Rik, TFII-I, BAP-135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Cnot6
Name: CCR4-NOT transcription complex, subunit 6
Synonyms: A230103N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 104625
Homologene: 69187
Agrn
Name: agrin
Synonyms: Agrin, NMF380, nmf380
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Zfp729a
Name: zinc finger protein 729a
Synonyms: A530054K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 212281
Homologene: 133713
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: 1200014O24Rik, Usp52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103135
VEGA: 10
Homologene: 5918
Vps35
Name: VPS35 retromer complex component
Synonyms: Mem3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 65114
Homologene: 6221
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: sys, F730017H24Rik, 1700094E19Rik, Fndc3, D14Ertd453e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 319448
Homologene: 8952
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20624
Homologene: 3133
N6amt1
Name: N-6 adenine-specific DNA methyltransferase 1 (putative)
Synonyms: Pred28, 5830445C04Rik, Hemk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67768
Homologene: 5637
Crot
Name: carnitine O-octanoyltransferase
Synonyms: 1200003H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74114
HGNC: HGNC:2366
Homologene: 10899
Rad17
Name: RAD17 checkpoint clamp loader component
Synonyms: 9430035O09Rik, MmRad24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19356
VEGA: 13
HGNC: HGNC:9807
Homologene: 32117
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: 2400004E04Rik, NMHC II-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71960
Homologene: 23480
Mphosph8
Name: M-phase phosphoprotein 8
Synonyms: 1500035L22Rik, 4930548G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 75339
Homologene: 11380
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329252
Homologene: 49680
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Gtl5, Wcrf180, Acf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Cryba2
Name: crystallin, beta A2
Synonyms: E130107M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12958
HGNC: HGNC:2395
Homologene: 10991
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: Sn, Siglec-1, CD169
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20612
Homologene: 124458
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 4632412F08Rik, 5330435L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237979
Homologene: 10406
Slc15a3
Name: solute carrier family 15, member 3
Synonyms: cI-1, Ci1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 65221
Homologene: 69222
Ifit1bl2
Name: interferon induced protein with tetratricopeptide repeats 1B like 2
Synonyms: 2010002M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 112419
Homologene: 78213
Amigo3
Name: adhesion molecule with Ig like domain 3
Synonyms: E430002N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320844
Homologene: 45570
Lzts2
Name: leucine zipper, putative tumor suppressor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226154
VEGA: 19
Homologene: 15690
Adam25
Name: a disintegrin and metallopeptidase domain 25 (testase 2)
Synonyms: testase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 23793
HGNC: HGNC:199
Homologene: 128364
Npr2
Name: natriuretic peptide receptor 2
Synonyms: guanylyl cyclase-B, cn, pwe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Arsa
Name: arylsulfatase A
Synonyms: As2, ASA, AS-A, As-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11883
HGNC: HGNC:713
Homologene: 20138
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241116
Homologene: 28093
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Folh1
Name: folate hydrolase 1
Synonyms: prostate-specific membrane antigen, mopsm, glutamate carboxypeptidase II, GCP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 53320
HGNC: HGNC:3788
Homologene: 55826
Dennd4b
Name: DENN/MADD domain containing 4B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229541
Homologene: 28281
Nudt12
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 12
Synonyms: 0610016O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67993
Homologene: 44188
Olfr1151
Name: olfactory receptor 1151
Synonyms: GA_x6K02T2Q125-49358694-49359620, MOR177-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258631
Homologene: 36999
Hipk3
Name: homeodomain interacting protein kinase 3
Synonyms: FIST3, DYRK6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15259
HGNC: HGNC:4915
Homologene: 55923
Gm4922
Name: predicted gene 4922
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237300
VEGA: 10
Homologene: 50497
Olfr430
Name: olfactory receptor 430
Synonyms: GA_x6K02T2P20D-21108443-21107490, MOR105-5P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258713
Homologene: 17362
Ssh3
Name: slingshot protein phosphatase 3
Synonyms: SSH-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 245857
VEGA: 19
Homologene: 32372
Sp110
Name: Sp110 nuclear body protein
Synonyms: Ifi75, Ipr1, 5031415C07Rik, 5830484A20Rik, 52kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Olfr1054
Name: olfactory receptor 1054
Synonyms: MOR188-2, GA_x6K02T2Q125-47811880-47810942
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 259021
Homologene: 133882
Spatc1l
Name: spermatogenesis and centriole associated 1 like
Synonyms: 1700022B01Rik, 1700027D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 76573
HGNC: HGNC:1298
Homologene: 75292
Ikzf2
Name: IKAROS family zinc finger 2
Synonyms: A730095J18Rik, Zfpn1a2, Helios
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22779
Homologene: 22659
Gm13938
Name: predicted gene 13938
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
2200002J24Rik
Name: RIKEN cDNA 2200002J24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69147
Homologene: 87038
Fam183b
Name: family with sequence similarity 183, member B
Synonyms: 3100002J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75429
Homologene: 28543
Sall2
Name: spalt like transcription factor 2
Synonyms: Msal-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 50524
Homologene: 9269
Olfr287
Name: olfactory receptor 287
Synonyms: GA_x6K02T2NBG7-5548201-5549154, MOR286-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 634104
Homologene: 128379
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 34,186,863 bp
  • T to C, chromosome 1 at 69,539,105 bp
  • A to T, chromosome 1 at 74,890,558 bp
  • G to A, chromosome 1 at 74,902,447 bp
  • A to G, chromosome 1 at 74,905,713 bp
  • G to A, chromosome 1 at 85,589,104 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • A to T, chromosome 1 at 174,069,466 bp
  • C to T, chromosome 2 at 76,756,996 bp
  • T to A, chromosome 2 at 86,332,841 bp
  • A to G, chromosome 2 at 87,857,355 bp
  • A to G, chromosome 2 at 104,471,698 bp
  • G to A, chromosome 2 at 131,079,377 bp
  • G to A, chromosome 3 at 90,271,178 bp
  • A to C, chromosome 4 at 43,643,654 bp
  • C to T, chromosome 4 at 156,177,225 bp
  • A to T, chromosome 5 at 8,993,504 bp
  • A to T, chromosome 5 at 14,225,655 bp
  • T to G, chromosome 5 at 134,242,894 bp
  • T to C, chromosome 7 at 30,699,784 bp
  • T to C, chromosome 7 at 44,630,002 bp
  • G to T, chromosome 7 at 86,771,881 bp
  • T to C, chromosome 8 at 40,755,476 bp
  • A to G, chromosome 8 at 85,279,054 bp
  • T to C, chromosome 9 at 108,053,852 bp
  • T to A, chromosome 10 at 18,784,338 bp
  • T to C, chromosome 10 at 76,563,907 bp
  • A to G, chromosome 10 at 128,318,238 bp
  • G to T, chromosome 11 at 49,685,103 bp
  • G to C, chromosome 11 at 53,570,581 bp
  • A to G, chromosome 11 at 58,801,794 bp
  • G to T, chromosome 11 at 102,840,044 bp
  • C to T, chromosome 11 at 113,838,646 bp
  • G to T, chromosome 11 at 116,230,068 bp
  • T to A, chromosome 12 at 54,895,000 bp
  • T to C, chromosome 13 at 67,619,675 bp
  • G to T, chromosome 13 at 100,633,899 bp
  • T to A, chromosome 14 at 52,313,203 bp
  • T to A, chromosome 14 at 56,674,259 bp
  • A to T, chromosome 14 at 72,589,807 bp
  • G to A, chromosome 15 at 89,474,225 bp
  • A to C, chromosome 15 at 98,208,342 bp
  • T to C, chromosome 16 at 87,356,198 bp
  • G to A, chromosome 17 at 59,011,037 bp
  • A to C, chromosome 19 at 4,266,549 bp
  • T to C, chromosome 19 at 10,855,980 bp
  • T to A, chromosome 19 at 34,619,485 bp
  • T to A, chromosome 19 at 45,023,544 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1079 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039165-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.