Strain Name:
C57BL/6J-MtgxR1081Btlr/Mmmh
Stock Number:
039167-MU
Citation ID:
RRID:MMRRC_039167-MU
Other Names:
R1081 (G1), C57BL/6J-MtgxR1081Btlr
Major Collection:

Gene Information

Ntsr1
Name: neurotensin receptor 1
Synonyms: NT-1R, Ntsr1, NTR-1, NTR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18216
HGNC: HGNC:8039
Homologene: 68261
Rpap1
Name: RNA polymerase II associated protein 1
Synonyms: 1190005L06Rik, A730023M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68925
Homologene: 32269
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57752
Homologene: 5087
Atxn2l
Name: ataxin 2-like
Synonyms: A2RP, A2LG, A2D, A2lp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233871
Homologene: 16513
Atxn3
Name: ataxin 3
Synonyms: Sca3, MJD1, 2210008M02Rik, ataxin-3, Mjd, Atx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110616
HGNC: HGNC:7106
Homologene: 3658
Wwc2
Name: WW, C2 and coiled-coil domain containing 2
Synonyms: D8Ertd594e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 52357
Homologene: 32618
Mepce
Name: methylphosphate capping enzyme
Synonyms: D5Wsu46e, Bcdin3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231803
Homologene: 32447
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: BC016423, Fam208b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Mob1b
Name: MOB kinase activator 1B
Synonyms: 1110003E08Rik, Mobkl1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68473
Homologene: 61676
Epg5
Name: ectopic P-granules autophagy protein 5 homolog (C. elegans)
Synonyms: 5430411K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 100502841
VEGA: 18
Homologene: 14575
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, Dnchc2, b2b414Clo, m407Asp, m152Asp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Farsa
Name: phenylalanyl-tRNA synthetase, alpha subunit
Synonyms: 0610012A19Rik, Farsla
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66590
HGNC: HGNC:3592
Homologene: 3280
Tcf25
Name: transcription factor 25 (basic helix-loop-helix)
Synonyms: 1810041K11Rik, Nulp1, 1100001J13Rik, D8Ertd325e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66855
Homologene: 5701
Trpc1
Name: transient receptor potential cation channel, subfamily C, member 1
Synonyms: Trrp1, Trp1, Mtrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22063
Homologene: 2478
Stat5a
Name: signal transducer and activator of transcription 5A
Synonyms: STAT5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20850
Homologene: 20680
P2rx4
Name: purinergic receptor P2X, ligand-gated ion channel 4
Synonyms: P2X4, D5Ertd444e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18438
HGNC: HGNC:8535
Homologene: 1923
Myof
Name: myoferlin
Synonyms: 2310051D19Rik, E030042N20Rik, Fer1l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Shtn1
Name: shootin 1
Synonyms: shootin1, 4930506M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71653
VEGA: 19
Homologene: 41249
Msh4
Name: mutS homolog 4
Synonyms: mMsh4, 4930485C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55993
HGNC: HGNC:7327
Homologene: 1830
Uckl1
Name: uridine-cytidine kinase 1-like 1
Synonyms: 1110007H10Rik, Urkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68556
Homologene: 101414
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, D430038H04Rik, 9430076A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 620292
VEGA: 17
Homologene: 128806
Vmn2r57
Name: vomeronasal 2, receptor 57
Synonyms: EG269902
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269902
Homologene: 104832
Sntg1
Name: syntrophin, gamma 1
Synonyms: G1SYN, SYN4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71096
Homologene: 56834
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Mink1
Name: misshapen-like kinase 1 (zebrafish)
Synonyms: Misshapen/NIKs-related kinase, MINK, Ysk2, Map4k6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50932
Homologene: 56762
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Zfp770
Name: zinc finger protein 770
Synonyms: 6430601A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228491
Homologene: 82354
Mndal
Name: myeloid nuclear differentiation antigen like
Synonyms: Ifi212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040462
HGNC: HGNC:5395
Homologene: 115929
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Zfp628
Name: zinc finger protein 628
Synonyms: Zec
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232816
Homologene: 72200
Trim7
Name: tripartite motif-containing 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94089
Homologene: 14113
1700003E16Rik
Name: RIKEN cDNA 1700003E16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71837
Homologene: 52846
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-a, Slp2, Slp2-d, Slp2-c, Slp2-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83671
Homologene: 131343
Olfr730
Name: olfactory receptor 730
Synonyms: GA_x6K02T2PMLR-5881670-5880717, MOR247-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258486
Homologene: 17269
Dsc2
Name: desmocollin 2
Synonyms: Dsc2b, Dsc2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13506
HGNC: HGNC:3036
Homologene: 8397
Cdh15
Name: cadherin 15
Synonyms: Cdh14, Mcad, M cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Gimap3
Name: GTPase, IMAP family member 3
Synonyms: 2010110D23Rik, Ian4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 83408
Homologene: 41257
Vmn2r24
Name: vomeronasal 2, receptor 24
Synonyms: EG243628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243628
Homologene: 135915
Zfp28
Name: zinc finger protein 28
Synonyms: mkr-5, Zfp-28, 2810438M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22690
Homologene: 69047
Lypd10
Name: Ly6/PLAUR domain containing 10
Synonyms: BC049730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232972
Olfr319
Name: olfactory receptor 319
Synonyms: GA_x6K02T2NKPP-708319-707399, MOR285-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258493
Klra6
Name: killer cell lectin-like receptor, subfamily A, member 6
Synonyms: Ly49F, Ly49f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16637
Homologene: 110821
Olfr598
Name: olfactory receptor 598
Synonyms: GA_x6K02T2PBJ9-6037823-6038782, MOR23-4P, MOR23-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257975
Homologene: 132401
Rpusd4
Name: RNA pseudouridylate synthase domain containing 4
Synonyms: 2410001E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71989
Homologene: 32794
Olfr66
Name: olfactory receptor 66
Synonyms: 5'[b]1, MOR1-3, GA_x6K02T2PBJ9-6620959-6620024
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18367
Homologene: 88376
1700034J04Rik
Name: RIKEN cDNA 1700034J04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
AC155270.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Kcnrg
Name: potassium channel regulator
Synonyms: LOC328424, E030012H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328424
VEGA: 14
Homologene: 35259
Ids
Name: iduronate 2-sulfatase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 15931
HGNC: HGNC:5389
Homologene: 169
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 8,445,119 bp
  • T to A, chromosome 1 at 173,860,222 bp
  • A to G, chromosome 2 at 114,197,127 bp
  • G to A, chromosome 2 at 119,771,269 bp
  • G to A, chromosome 2 at 180,538,756 bp
  • G to C, chromosome 2 at 181,570,490 bp
  • T to C, chromosome 3 at 153,872,358 bp
  • G to A, chromosome 5 at 88,753,162 bp
  • A to G, chromosome 5 at 122,727,233 bp
  • A to G, chromosome 5 at 137,784,696 bp
  • A to T, chromosome 6 at 48,765,152 bp
  • A to G, chromosome 6 at 83,162,020 bp
  • C to A, chromosome 6 at 123,815,379 bp
  • A to G, chromosome 6 at 130,022,625 bp
  • A to G, chromosome 7 at 4,920,183 bp
  • A to G, chromosome 7 at 6,389,780 bp
  • T to C, chromosome 7 at 24,713,542 bp
  • A to G, chromosome 7 at 41,428,211 bp
  • T to C, chromosome 7 at 90,403,020 bp
  • A to G, chromosome 7 at 103,329,038 bp
  • T to A, chromosome 7 at 103,882,177 bp
  • T to C, chromosome 7 at 126,494,212 bp
  • A to G, chromosome 7 at 130,728,574 bp
  • G to A, chromosome 8 at 47,828,764 bp
  • A to G, chromosome 8 at 82,069,024 bp
  • T to C, chromosome 8 at 84,861,301 bp
  • G to C, chromosome 8 at 122,857,495 bp
  • T to C, chromosome 8 at 123,381,473 bp
  • A to T, chromosome 9 at 7,005,488 bp
  • T to C, chromosome 9 at 16,375,284 bp
  • A to G, chromosome 9 at 35,275,088 bp
  • A to T, chromosome 9 at 95,743,183 bp
  • A to G, chromosome 10 at 74,450,313 bp
  • G to T, chromosome 11 at 48,849,705 bp
  • C to T, chromosome 11 at 58,702,498 bp
  • A to G, chromosome 11 at 66,084,877 bp
  • T to C, chromosome 11 at 70,607,035 bp
  • T to C, chromosome 11 at 76,455,615 bp
  • T to C, chromosome 11 at 100,881,060 bp
  • T to C, chromosome 12 at 11,221,935 bp
  • T to A, chromosome 12 at 27,142,029 bp
  • T to G, chromosome 12 at 101,934,349 bp
  • A to T, chromosome 13 at 3,570,304 bp
  • G to A, chromosome 13 at 100,423,070 bp
  • A to G, chromosome 14 at 50,187,197 bp
  • C to A, chromosome 14 at 61,607,714 bp
  • A to G, chromosome 17 at 58,305,525 bp
  • T to G, chromosome 18 at 20,033,295 bp
  • T to C, chromosome 18 at 77,959,533 bp
  • A to T, chromosome 19 at 37,986,088 bp
  • T to A, chromosome 19 at 58,975,015 bp
  • T to C, chromosome X at 70,361,110 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1081 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039167-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.