Strain Name:
C57BL/6J-MtgxR1101Btlr/Mmmh
Stock Number:
039174-MU
Citation ID:
RRID:MMRRC_039174-MU
Other Names:
R1101 (G1), C57BL/6J-MtgxR1101Btlr
Major Collection:

Gene Information

Dct
Name: dopachrome tautomerase
Synonyms: tyrosinase-related protein-2, TRP2, TRP-2, Tyrp-2, Tyrp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 13190
VEGA: 14
HGNC: HGNC:2709
Homologene: 1447
Trdmt1
Name: tRNA aspartic acid methyltransferase 1
Synonyms: Rnmt2, Dnmt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13434
HGNC: HGNC:2977
Homologene: 3249
Sirt3
Name: sirtuin 3
Synonyms: 2310003L23Rik, Sir2l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 64384
Homologene: 81827
Oxtr
Name: oxytocin receptor
Synonyms: OTR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18430
HGNC: HGNC:8529
Homologene: 20255
Igf2bp2
Name: insulin-like growth factor 2 mRNA binding protein 2
Synonyms: IMP2, C330012H03Rik, IMP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 319765
Homologene: 4774
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 208440
Homologene: 40996
Sptlc1
Name: serine palmitoyltransferase, long chain base subunit 1
Synonyms: Lcb1, Spt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 268656
VEGA: 13
Homologene: 4681
Lrrfip2
Name: leucine rich repeat (in FLII) interacting protein 2
Synonyms: 5133400F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71268
HGNC: HGNC:6703
Homologene: 22476
Ireb2
Name: iron responsive element binding protein 2
Synonyms: D9Ertd85e, Irp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 64602
VEGA: 9
HGNC: HGNC:6115
Homologene: 11280
Prep
Name: prolyl endopeptidase
Synonyms: prolyl oligopeptidase, D10Wsu136e, Pop
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19072
VEGA: 10
HGNC: HGNC:9358
Homologene: 2042
Polr2a
Name: polymerase (RNA) II (DNA directed) polypeptide A
Synonyms: Rpo2-1, 220kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20020
HGNC: HGNC:9187
Homologene: 721
2610021A01Rik
Name: RIKEN cDNA 2610021A01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 668572
Atp2c1
Name: ATPase, Ca++-sequestering
Synonyms: ATP2C1A, 1700121J11Rik, SPCA, PMR1, D930003G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235574
Homologene: 56672
Eif3l
Name: eukaryotic translation initiation factor 3, subunit L
Synonyms: Eif3eip, D15N1e, 0610011H21Rik, PAF67, HSP-66Y, Eif3s6ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223691
VEGA: 15
Homologene: 9380
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: mei2-5, G1-448-15, 5730481H23Rik, AKAP450, repro12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Vps72
Name: vacuolar protein sorting 72
Synonyms: Tcfl1, YL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 21427
Homologene: 110905
Supt16
Name: SPT16, facilitates chromatin remodeling subunit
Synonyms: Fact140, Supt16h, Spt16, Cdc68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 114741
VEGA: 14
Homologene: 5207
Hdac2
Name: histone deacetylase 2
Synonyms: Yy1bp, D10Wsu179e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15182
HGNC: HGNC:4853
Homologene: 68187
Tbr1
Name: T-box brain gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 21375
Homologene: 4807
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: Smek1, 1110034C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68734
VEGA: 12
Homologene: 69510
Lman1
Name: lectin, mannose-binding, 1
Synonyms: MCFD1, P58, gp58, ERGIC53, MR60, F5F8D, 2610020P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70361
HGNC: HGNC:6631
Homologene: 4070
Enpp5
Name: ectonucleotide pyrophosphatase/phosphodiesterase 5
Synonyms: D17Abb1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 83965
Homologene: 23313
Mtr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Synonyms: MS, D830038K18Rik, methionine synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238505
VEGA: 13
HGNC: HGNC:7468
Homologene: 37280
Dapk1
Name: death associated protein kinase 1
Synonyms: 2810425C21Rik, 2310039H24Rik, DAP-Kinase, D13Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Dhx37
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 37
Synonyms: LOC208144, LOC381671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 208144
Homologene: 6641
Clcn2
Name: chloride channel, voltage-sensitive 2
Synonyms: nmf240, Clc2, ClC-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12724
HGNC: HGNC:2020
Homologene: 3213
Adcy3
Name: adenylate cyclase 3
Synonyms: ACIII, AC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104111
HGNC: HGNC:234
Homologene: 2978
Olfr173
Name: olfactory receptor 173
Synonyms: MOR184-3, GA_x54KRFPKG5P-54960233-54959268
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 259002
HGNC: HGNC:8349
Homologene: 45084
Mast3
Name: microtubule associated serine/threonine kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 546071
Homologene: 66191
Plppr5
Name: phospholipid phosphatase related 5
Synonyms: 4833424O15Rik, Lppr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75769
Homologene: 25279
Prg4
Name: proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
Synonyms: SZP, MSF, DOL54, lubricin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 96875
HGNC: HGNC:9364
Homologene: 137352
St8sia2
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Synonyms: ST8SiaII, Siat8b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20450
Homologene: 4384
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Pcdh18
Name: protocadherin 18
Synonyms: PCDH68L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 73173
Homologene: 10389
Zmynd15
Name: zinc finger, MYND-type containing 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 574428
Homologene: 12995
Emcn
Name: endomucin
Synonyms: 0610012K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 59308
Homologene: 9438
Fam83b
Name: family with sequence similarity 83, member B
Synonyms: C530008M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208994
Homologene: 19478
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: PI3Kgamma, p110gamma, PI3Kgamma, 5830428L06Rik, PI(3)Kgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
Mep1a
Name: meprin 1 alpha
Synonyms: Mep-1a, Mep-1, Mep1, meprin A alpha-subunit, meprin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17287
HGNC: HGNC:7015
Homologene: 31323
Bank1
Name: B cell scaffold protein with ankyrin repeats 1
Synonyms: A530094C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242248
Homologene: 9926
Scgb2b27
Name: secretoglobin, family 2B, member 27
Synonyms: Abpbg27, Abpbg5, C2a, Abpb, Scgb2b5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233099
Homologene: 83171
1700034J05Rik
Name: RIKEN cDNA 1700034J05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 73344
Homologene: 53485
Serpinb9e
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9e
Synonyms: NK26, Spi14, ovalbumin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20710
HGNC: HGNC:8955
Homologene: 69093
Olfr1212
Name: olfactory receptor 1212
Synonyms: MOR233-20, GA_x6K02T2Q125-50437014-50437949, MOR233-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258241
Homologene: 66154
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Cdh15
Name: cadherin 15
Synonyms: Mcad, Cdh14, M cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74918
Homologene: 49784
Abi3bp
Name: ABI gene family, member 3 (NESH) binding protein
Synonyms: TARSH, eratin, D930038M13Rik, 5033411B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 320712
VEGA: 16
Homologene: 134172
Ogfod1
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 1
Synonyms: 4930415J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270086
Homologene: 41238
Acot2
Name: acyl-CoA thioesterase 2
Synonyms: Mte1, MTE-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 171210
Homologene: 25661
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243944
Homologene: 77912
Ndst1
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Synonyms: Hsst, b2b2230Clo, 1200015G06Rik, Ndst-1, glucosaminyl N-deacetylase/N-sulfotransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 15531
VEGA: 18
HGNC: HGNC:7680
Homologene: 20386
Fcamr
Name: Fc receptor, IgA, IgM, high affinity
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 64435
Homologene: 12929
Olfr1290
Name: olfactory receptor 1290
Synonyms: GA_x6K02T2Q125-72541649-72540711, MOR248-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257662
Homologene: 74248
Ptms
Name: parathymosin
Synonyms: 2610009E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69202
HGNC: HGNC:9629
Trim72
Name: tripartite motif-containing 72
Synonyms: mitsugumin 53, MG53
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434246
Homologene: 66924
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 90,142,731 bp
  • T to A, chromosome 1 at 130,814,486 bp
  • C to T, chromosome 1 at 150,462,092 bp
  • T to G, chromosome 2 at 13,523,414 bp
  • T to C, chromosome 2 at 61,804,739 bp
  • A to T, chromosome 2 at 88,958,984 bp
  • T to C, chromosome 2 at 111,489,442 bp
  • T to A, chromosome 3 at 49,753,379 bp
  • C to A, chromosome 3 at 95,119,176 bp
  • T to G, chromosome 3 at 117,662,523 bp
  • T to C, chromosome 3 at 136,283,864 bp
  • T to A, chromosome 3 at 137,372,717 bp
  • T to C, chromosome 5 at 4,046,205 bp
  • A to G, chromosome 5 at 125,415,152 bp
  • C to T, chromosome 6 at 112,477,177 bp
  • A to G, chromosome 6 at 124,914,241 bp
  • T to C, chromosome 6 at 146,952,411 bp
  • C to T, chromosome 7 at 34,013,167 bp
  • A to T, chromosome 7 at 40,993,056 bp
  • C to A, chromosome 7 at 41,627,359 bp
  • A to G, chromosome 7 at 73,971,906 bp
  • A to G, chromosome 7 at 128,010,247 bp
  • A to G, chromosome 7 at 140,869,628 bp
  • T to A, chromosome 8 at 70,786,663 bp
  • C to A, chromosome 8 at 94,064,304 bp
  • G to A, chromosome 8 at 122,860,846 bp
  • T to A, chromosome 9 at 54,909,702 bp
  • A to T, chromosome 9 at 76,545,670 bp
  • A to T, chromosome 9 at 105,466,682 bp
  • A to G, chromosome 9 at 108,116,411 bp
  • C to T, chromosome 9 at 111,190,225 bp
  • G to A, chromosome 10 at 36,991,809 bp
  • T to A, chromosome 10 at 45,115,269 bp
  • T to C, chromosome 11 at 69,748,071 bp
  • T to C, chromosome 11 at 70,462,031 bp
  • T to C, chromosome 12 at 4,206,990 bp
  • C to T, chromosome 12 at 32,195,646 bp
  • T to G, chromosome 12 at 83,992,850 bp
  • C to A, chromosome 12 at 101,051,571 bp
  • A to T, chromosome 13 at 9,634,744 bp
  • C to A, chromosome 13 at 12,189,525 bp
  • A to T, chromosome 13 at 33,260,088 bp
  • A to G, chromosome 13 at 53,333,987 bp
  • A to G, chromosome 13 at 60,716,785 bp
  • T to C, chromosome 14 at 30,887,800 bp
  • T to C, chromosome 14 at 52,171,439 bp
  • T to G, chromosome 14 at 118,036,622 bp
  • A to G, chromosome 15 at 79,075,267 bp
  • G to A, chromosome 16 at 20,703,595 bp
  • A to T, chromosome 16 at 22,162,950 bp
  • G to T, chromosome 16 at 56,606,158 bp
  • A to G, chromosome 16 at 58,797,252 bp
  • T to C, chromosome 17 at 43,491,693 bp
  • A to G, chromosome 17 at 44,081,367 bp
  • T to C, chromosome 18 at 60,707,598 bp
  • T to A, chromosome 18 at 65,987,898 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1101 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039174-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.