Strain Name:
C57BL/6J-MtgxR1118Btlr/Mmmh
Stock Number:
039191-MU
Citation ID:
RRID:MMRRC_039191-MU
Other Names:
R1118 (G1), C57BL/6J-MtgxR1118Btlr
Major Collection:

Gene Information

Vcan
Name: versican
Synonyms: PG-M, hdf, heart defect, 5430420N07Rik, DPEAAE, Cspg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Gap43
Name: growth associated protein 43
Synonyms: B-50, neuromodulin, GAP-43, Basp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14432
HGNC: HGNC:4140
Homologene: 1545
Tagln3
Name: transgelin 3
Synonyms: 2700038H05Rik, 2900005O10Rik, Np25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56370
Homologene: 22337
Smg7
Name: Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
Synonyms: 9430023P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226517
Homologene: 32235
Prdm2
Name: PR domain containing 2, with ZNF domain
Synonyms: Riz, Riz1, LOC381568, E330024L24Rik, 4833427P12Rik, KMT8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 110593
HGNC: HGNC:9347
Homologene: 40822
Pdxdc1
Name: pyridoxal-dependent decarboxylase domain containing 1
Synonyms: 2210010A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 94184
Homologene: 22858
Ticrr
Name: TOPBP1-interacting checkpoint and replication regulator
Synonyms: 5730590G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77011
Homologene: 67120
Ttc3
Name: tetratricopeptide repeat domain 3
Synonyms: TPRD, D16Ium21, 2610202A04Rik, D16Ium21e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22129
Homologene: 2487
Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Synonyms: 5033407O22Rik, 4833414K03Rik, CHAK1, CHAK, TRP-PLIK, Ltpr7, 2310022G15Rik, LTRPC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 58800
Homologene: 9774
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, D9Ertd809e, Dopey1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320615
Homologene: 26645
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22019
Homologene: 2471
Gsk3b
Name: glycogen synthase kinase 3 beta
Synonyms: GSK-3beta, GSK-3, 8430431H08Rik, 7330414F15Rik, GSK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56637
HGNC: HGNC:4617
Homologene: 55629
Ndufa9
Name: NADH:ubiquinone oxidoreductase subunit A9
Synonyms: 1010001N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66108
HGNC: HGNC:7693
Homologene: 3666
Gtf3c3
Name: general transcription factor IIIC, polypeptide 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98488
HGNC: HGNC:4666
Homologene: 40805
Bcan
Name: brevican
Synonyms: Cspg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12032
Homologene: 7244
Mei1
Name: meiotic double-stranded break formation protein 1
Synonyms: mei1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74369
Homologene: 46535
Creld1
Name: cysteine-rich with EGF-like domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171508
Homologene: 32265
Tia1
Name: cytotoxic granule-associated RNA binding protein 1
Synonyms: mTIA-1, 2310050N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21841
Homologene: 20692
Kif22
Name: kinesin family member 22
Synonyms: Kif22a, Kid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 110033
HGNC: HGNC:6391
Homologene: 32011
Smad4
Name: SMAD family member 4
Synonyms: DPC4, Smad 4, Dpc4, D18Wsu70e, Madh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17128
HGNC: HGNC:6770
Homologene: 31310
Lbr
Name: lamin B receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98386
HGNC: HGNC:6518
Homologene: 2455
Zfp958
Name: zinc finger protein 958
Synonyms: BC003267
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 233987
Homologene: 129582
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 623474
Homologene: 8240
Slc9a4
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 4
Synonyms: NHE4, D730009J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 110895
Homologene: 72232
Grina
Name: glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
Synonyms: 1110025J15Rik, Tmbim3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66168
VEGA: 15
HGNC: HGNC:4589
Homologene: 41517
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, Crsh, crash, Adgrc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
4932431P20Rik
Name: RIKEN cDNA 4932431P20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 114675
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 192188
Homologene: 23022
Nlrp9c
Name: NLR family, pyrin domain containing 9C
Synonyms: Nalp-zeta, Nalp9c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330490
Homologene: 116072
Ces1f
Name: carboxylesterase 1F
Synonyms: TGH-2, CesML1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234564
HGNC: HGNC:1863
Homologene: 134311
Cped1
Name: cadherin-like and PC-esterase domain containing 1
Synonyms: A430107O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 214642
Homologene: 57014
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81877
Homologene: 49589
Cd200r2
Name: Cd200 receptor 2
Synonyms: CD200 cell surface glycoprotein receptor isoform 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 271375
Homologene: 45557
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Wrap73
Name: WD repeat containing, antisense to Trp73
Synonyms: DD57, 2610044M17Rik, 5330425N03Rik, Wdr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 59002
Homologene: 9857
Tex14
Name: testis expressed gene 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 83560
Homologene: 12838
Pcnp
Name: PEST proteolytic signal containing nuclear protein
Synonyms: 1110018D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 76302
Homologene: 10676
Itprid1
Name: ITPR interacting domain containing 1
Synonyms: D530004J12Rik, Ccdc129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232016
Homologene: 52344
Apcdd1
Name: adenomatosis polyposis coli down-regulated 1
Synonyms: EIG180, Drapc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 494504
VEGA: 18
Homologene: 77420
Fam71a
Name: family with sequence similarity 71, member A
Synonyms: 4933417M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 619288
Homologene: 77474
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: 6720455I24Rik, Snep, D430044C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208777
Homologene: 14708
Pcdhb15
Name: protocadherin beta 15
Synonyms: Pcdhb7, PcdhbO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93886
HGNC: HGNC:8692
Homologene: 32429
Vmn2r107
Name: vomeronasal 2, receptor 107
Synonyms: V2r6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22312
Homologene: 129750
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Stk36
Name: serine/threonine kinase 36
Synonyms: 1700112N14Rik, Fused
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269209
Homologene: 49432
Haus6
Name: HAUS augmin-like complex, subunit 6
Synonyms: D4Ertd27e, 6230416J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230376
Homologene: 9760
Otud4
Name: OTU domain containing 4
Synonyms: 4930431L18Rik, D8Ertd69e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73945
Homologene: 35370
Card10
Name: caspase recruitment domain family, member 10
Synonyms: CARMA3, Bimp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105844
Homologene: 8728
Olfr1306
Name: olfactory receptor 1306
Synonyms: GA_x6K02T2Q125-72954873-72953935, MOR245-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258023
Homologene: 128383
Fhl3
Name: four and a half LIM domains 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14201
HGNC: HGNC:3704
Homologene: 37928
Pgc
Name: progastricsin (pepsinogen C)
Synonyms: Upg-1, Upg1, 2210410L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 109820
HGNC: HGNC:8890
Homologene: 55669
Mrgpra3
Name: MAS-related GPR, member A3
Synonyms: G protein-coupled receptor, MrgA3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233222
Homologene: 131159
P4ha3
Name: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
Synonyms: D930031A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320452
Homologene: 27943
Dusp7
Name: dual specificity phosphatase 7
Synonyms: PYST2, MKP-X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235584
HGNC: HGNC:3073
Homologene: 1468
Misp
Name: mitotic spindle positioning
Synonyms: 9130017N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78906
VEGA: 10
Homologene: 49933
Phf11a
Name: PHD finger protein 11A
Synonyms: 4933417L10Rik, Phf11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219131
Homologene: 87807
Slc52a2
Name: solute carrier protein 52, member 2
Synonyms: 2010003P03Rik, GPCR42, PAR2, D15Ertd747e, Gpr172b, Rfvt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 52710
VEGA: 15
Homologene: 56994
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 40,584,330 bp
  • T to C, chromosome 1 at 43,992,396 bp
  • C to T, chromosome 1 at 54,417,778 bp
  • A to G, chromosome 1 at 74,632,766 bp
  • G to A, chromosome 1 at 93,281,654 bp
  • C to T, chromosome 1 at 150,618,928 bp
  • A to T, chromosome 1 at 152,866,575 bp
  • A to C, chromosome 1 at 181,820,668 bp
  • G to A, chromosome 1 at 191,164,485 bp
  • T to C, chromosome 2 at 13,336,242 bp
  • T to A, chromosome 2 at 111,912,877 bp
  • A to G, chromosome 2 at 126,822,486 bp
  • A to T, chromosome 3 at 38,982,942 bp
  • T to A, chromosome 3 at 87,989,227 bp
  • T to C, chromosome 4 at 11,563,352 bp
  • A to G, chromosome 4 at 86,585,326 bp
  • T to C, chromosome 4 at 124,705,791 bp
  • G to A, chromosome 4 at 143,132,383 bp
  • A to T, chromosome 4 at 154,152,427 bp
  • A to T, chromosome 6 at 22,237,699 bp
  • A to G, chromosome 6 at 48,459,418 bp
  • T to C, chromosome 6 at 55,889,170 bp
  • G to A, chromosome 6 at 86,419,109 bp
  • A to G, chromosome 6 at 113,491,695 bp
  • A to T, chromosome 6 at 126,822,068 bp
  • A to T, chromosome 7 at 26,384,437 bp
  • G to A, chromosome 7 at 29,534,244 bp
  • A to C, chromosome 7 at 47,589,291 bp
  • C to T, chromosome 7 at 79,693,953 bp
  • T to C, chromosome 7 at 100,313,328 bp
  • A to G, chromosome 7 at 127,032,744 bp
  • A to T, chromosome 8 at 4,626,169 bp
  • C to T, chromosome 8 at 79,653,351 bp
  • A to G, chromosome 8 at 93,267,242 bp
  • A to G, chromosome 9 at 86,515,406 bp
  • T to C, chromosome 9 at 106,373,650 bp
  • T to C, chromosome 10 at 79,827,135 bp
  • A to T, chromosome 10 at 86,885,718 bp
  • A to T, chromosome 11 at 87,522,517 bp
  • G to A, chromosome 13 at 89,705,663 bp
  • C to A, chromosome 14 at 30,896,167 bp
  • T to C, chromosome 14 at 59,284,329 bp
  • T to C, chromosome 15 at 76,248,579 bp
  • T to C, chromosome 15 at 76,539,608 bp
  • T to C, chromosome 15 at 78,802,443 bp
  • G to A, chromosome 15 at 82,115,867 bp
  • T to C, chromosome 15 at 86,032,047 bp
  • T to A, chromosome 16 at 13,879,414 bp
  • T to C, chromosome 16 at 38,207,984 bp
  • T to C, chromosome 16 at 42,291,804 bp
  • A to G, chromosome 16 at 44,909,606 bp
  • C to A, chromosome 16 at 45,724,272 bp
  • A to G, chromosome 16 at 56,024,391 bp
  • T to A, chromosome 16 at 94,416,268 bp
  • G to A, chromosome 17 at 20,356,598 bp
  • G to A, chromosome 17 at 34,685,043 bp
  • T to A, chromosome 17 at 47,728,903 bp
  • T to A, chromosome 18 at 37,473,762 bp
  • A to G, chromosome 18 at 62,952,024 bp
  • T to C, chromosome 18 at 73,640,262 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1118 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039191-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.