Strain Name:
C57BL/6J-MtgxR1288Btlr/Mmmh
Stock Number:
039354-MU
Citation ID:
RRID:MMRRC_039354-MU
Other Names:
R1288 (G1), C57BL/6J-MtgxR1288Btlr
Major Collection:

Gene Information

Atxn3
Name: ataxin 3
Synonyms: Sca3, MJD1, 2210008M02Rik, ataxin-3, Mjd, Atx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110616
HGNC: HGNC:7106
Homologene: 3658
Sltm
Name: SAFB-like, transcription modulator
Synonyms: 5730455C01Rik, 9130215G10Rik, 5730555F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66660
VEGA: 9
Homologene: 11696
Enoph1
Name: enolase-phosphatase 1
Synonyms: 2310057D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67870
Homologene: 5790
Trhde
Name: TRH-degrading enzyme
Synonyms: 9330155P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237553
Homologene: 75007
Rapgef3
Name: Rap guanine nucleotide exchange factor (GEF) 3
Synonyms: 2310016P22Rik, 9330170P05Rik, Epac1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223864
Homologene: 21231
Anpep
Name: alanyl (membrane) aminopeptidase
Synonyms: Cd13, aminopeptidase N, Apn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243277
Homologene: 34616
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: extraocular myosin, EO Myosin, MyHC-eo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Lrp12
Name: low density lipoprotein-related protein 12
Synonyms: C820005L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239393
Homologene: 8385
Fbxw28
Name: F-box and WD-40 domain protein 28
Synonyms: Gm9337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 668758
Homologene: 110776
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 234915
VEGA: 9
Homologene: 28313
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
BC005537
Name: cDNA sequence BC005537
Synonyms: 8030460C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 79555
Homologene: 11551
Olfr68
Name: olfactory receptor 68
Synonyms: 3'[b]2, MOR22-3, GA_x6K02T2PBJ9-6504436-6503489
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18369
Homologene: 130658
Nme8
Name: NME/NM23 family member 8
Synonyms: 1700056P15Rik, Sptrx-2, Txndc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 73412
Homologene: 9593
Ano5
Name: anoctamin 5
Synonyms: Gdd1, Tmem16e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233246
Homologene: 100071
Olfr822
Name: olfactory receptor 822
Synonyms: GA_x6K02T2PULF-11745102-11746040, MOR113-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258666
Homologene: 133890
Olfr123
Name: olfactory receptor 123
Synonyms: MOR256-9, GA_x6K02T2PSCP-2255106-2256035
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258623
Homologene: 105169
Gvin-ps6
Name: GTPase, very large interferon inducible, pseudogene 6
Synonyms: Gm4759
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 209380
Olfr138
Name: olfactory receptor 138
Synonyms: Olfr89, MOR256-40P, GA_x6K02T2PSCP-2718585-2719523
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 170648
Homologene: 119758
Msl2
Name: MSL complex subunit 2
Synonyms: E130103E02Rik, Rnf184, Msl2l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 77853
Homologene: 10021
Olfr1135
Name: olfactory receptor 1135
Synonyms: GA_x6K02T2Q125-49177531-49176599, MOR177-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258654
Homologene: 17331
Atxn7l2
Name: ataxin 7-like 2
Synonyms: 2610528J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72522
Homologene: 17728
Vmn1r234
Name: vomeronasal 1 receptor 234
Synonyms: V1rf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171232
Mup21
Name: major urinary protein 21
Synonyms: Gm11208
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381531
Homologene: 74304
Nkg7
Name: natural killer cell group 7 sequence
Synonyms: 2500004F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72310
HGNC: HGNC:7830
Homologene: 4092
Zfp40
Name: zinc finger protein 40
Synonyms: NTfin12, Zfp-40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22700
Homologene: 136312
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 54,364,458 bp
  • G to A, chromosome 2 at 87,671,572 bp
  • A to G, chromosome 3 at 108,204,048 bp
  • G to T, chromosome 4 at 62,150,697 bp
  • A to G, chromosome 5 at 100,040,279 bp
  • A to T, chromosome 5 at 129,129,007 bp
  • A to G, chromosome 7 at 43,437,662 bp
  • A to T, chromosome 7 at 51,546,872 bp
  • C to T, chromosome 7 at 79,838,256 bp
  • A to T, chromosome 7 at 103,778,042 bp
  • A to G, chromosome 7 at 106,423,183 bp
  • A to T, chromosome 9 at 8,112,181 bp
  • T to A, chromosome 9 at 70,576,853 bp
  • A to G, chromosome 9 at 101,102,109 bp
  • A to G, chromosome 9 at 109,337,293 bp
  • T to A, chromosome 10 at 114,801,290 bp
  • A to G, chromosome 10 at 130,075,285 bp
  • T to C, chromosome 11 at 67,353,718 bp
  • C to T, chromosome 12 at 101,942,178 bp
  • A to G, chromosome 13 at 19,674,449 bp
  • A to T, chromosome 13 at 24,804,900 bp
  • A to T, chromosome 15 at 39,878,403 bp
  • C to A, chromosome 15 at 97,759,342 bp
  • CTT to CTTT, chromosome 17 at 21,229,251 bp
  • T to A, chromosome 17 at 23,182,162 bp
  • T to A, chromosome 17 at 37,795,693 bp
  • A to G, chromosome 17 at 38,275,223 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1288 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039354-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.