Strain Name:
C57BL/6J-MtgxR1307Btlr/Mmmh
Stock Number:
039373-MU
Citation ID:
RRID:MMRRC_039373-MU
Other Names:
R1307 (G1), C57BL/6J-MtgxR1307Btlr
Major Collection:

Gene Information

Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: Fadk, FAK, FRNK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Cep57
Name: centrosomal protein 57
Synonyms: 3110002L15Rik, 4921510P06Rik, Tsp57, 4931428M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74360
Homologene: 8790
Ascc1
Name: activating signal cointegrator 1 complex subunit 1
Synonyms: CGI-18, ASC1p50, 1810015P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 69090
VEGA: 10
Homologene: 41079
Zfp985
Name: zinc finger protein 985
Synonyms: Gm13154
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433804
Homologene: 133076
Polr3f
Name: polymerase (RNA) III (DNA directed) polypeptide F
Synonyms: RPC39, 3110032A07Rik, 3010019O03Rik, RPC6, 2810411G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70408
Homologene: 4722
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: G630013P12Rik, TFIIIB90, TAF3B1, B130055N23Rik, TFC5, TFIIIB150, Tfnr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544971
Homologene: 34582
Sphk1
Name: sphingosine kinase 1
Synonyms: SK1, 1110006G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20698
Homologene: 39748
Muc2
Name: mucin 2
Synonyms: 2010015E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17831
HGNC: HGNC:7512
Homologene: 136755
Tnc
Name: tenascin C
Synonyms: tenascin-C, TN, hexabrachion, TN-C, cytotactin, Hxb, C130033P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Havcr1
Name: hepatitis A virus cellular receptor 1
Synonyms: KIM-1, TIM-1, Tim1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171283
Homologene: 136301
Kdm4a
Name: lysine (K)-specific demethylase 4A
Synonyms: Jmjd2, Jmjd2a, JHDM3A, D4Ertd222e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230674
Homologene: 27780
Sv2b
Name: synaptic vesicle glycoprotein 2 b
Synonyms: A830038F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 64176
Homologene: 32236
Slc25a28
Name: solute carrier family 25, member 28
Synonyms: 2210403D18Rik, Mrs3/4, Mfrn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 246696
VEGA: 19
Homologene: 56208
Cabp1
Name: calcium binding protein 1
Synonyms: caldendrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 29867
HGNC: HGNC:1384
Homologene: 99790
Ush2a
Name: usherin
Synonyms: LOC269160, Ushrn, A930037M10Rik, A930011D15Rik, LOC381317, MUSH2A, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Sybu
Name: syntabulin (syntaxin-interacting)
Synonyms: A830027B17Rik, 5730410E15Rik, Golsyn/Syntabulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319613
VEGA: 15
Homologene: 9838
Pcdh10
Name: protocadherin 10
Synonyms: OL-pc, 6430703F07Rik, 6430521D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18526
Homologene: 74967
Unc79
Name: unc-79 homolog
Synonyms: Mlca3, 9030205A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217843
Homologene: 41397
Coq8b
Name: coenzyme Q8B
Synonyms: Adck4, 0610012P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76889
Homologene: 86731
Syce1l
Name: synaptonemal complex central element protein 1 like
Synonyms: mmrp2, 4930481F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 668110
Homologene: 86343
Uba52
Name: ubiquitin A-52 residue ribosomal protein fusion product 1
Synonyms: D8Ertd21e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 22186
Homologene: 135114
Ntn4
Name: netrin 4
Synonyms: beta-netrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 57764
Homologene: 10934
Rhof
Name: ras homolog family member F (in filopodia)
Synonyms: Ifld1, Arhf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 23912
Homologene: 41304
Bcl2a1b
Name: B cell leukemia/lymphoma 2 related protein A1b
Synonyms: A1-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12045
HGNC: HGNC:991
Homologene: 2988
Gk2
Name: glycerol kinase 2
Synonyms: Gk-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14626
HGNC: HGNC:4291
Homologene: 133273
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 188,357,967 bp
  • T to C, chromosome 1 at 188,451,840 bp
  • T to C, chromosome 2 at 144,533,193 bp
  • A to G, chromosome 3 at 45,381,879 bp
  • T to C, chromosome 4 at 64,008,859 bp
  • T to C, chromosome 4 at 118,175,642 bp
  • C to T, chromosome 4 at 147,583,247 bp
  • A to T, chromosome 5 at 97,455,409 bp
  • A to G, chromosome 5 at 115,172,906 bp
  • T to C, chromosome 5 at 123,120,315 bp
  • T to A, chromosome 7 at 27,250,591 bp
  • G to T, chromosome 7 at 75,206,434 bp
  • C to T, chromosome 7 at 141,754,192 bp
  • T to C, chromosome 8 at 70,508,516 bp
  • T to C, chromosome 8 at 113,651,738 bp
  • T to C, chromosome 9 at 13,818,320 bp
  • T to C, chromosome 9 at 89,199,490 bp
  • A to T, chromosome 10 at 39,070,032 bp
  • A to T, chromosome 10 at 60,012,499 bp
  • C to T, chromosome 10 at 93,707,353 bp
  • C to T, chromosome 11 at 46,756,270 bp
  • G to A, chromosome 11 at 116,536,102 bp
  • A to G, chromosome 12 at 103,070,076 bp
  • T to C, chromosome 13 at 100,049,763 bp
  • T to C, chromosome 15 at 44,675,390 bp
  • A to G, chromosome 15 at 73,292,046 bp
  • T to C, chromosome 19 at 43,667,031 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1307 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039373-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.