Strain Name:
C57BL/6J-MtgxR1310Btlr/Mmmh
Stock Number:
039376-MU
Citation ID:
RRID:MMRRC_039376-MU
Other Names:
R1310 (G1), C57BL/6J-MtgxR1310Btlr
Major Collection:

Gene Information

Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: TM7LN3, Emr1, DD7A5-7, EGF-TM7, F4/80, Ly71
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Sik3
Name: SIK family kinase 3
Synonyms: 9030204A07Rik, 5730525O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70661
Homologene: 57023
Soat1
Name: sterol O-acyltransferase 1
Synonyms: hid, Acact, ACAT-1, 8430426K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20652
Homologene: 2333
Drd3
Name: dopamine receptor D3
Synonyms: D3R, D3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13490
VEGA: 16
HGNC: HGNC:3024
Homologene: 623
Bcl10
Name: B cell leukemia/lymphoma 10
Synonyms: cE10, mE10, BCL-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12042
HGNC: HGNC:989
Homologene: 2912
C87436
Name: expressed sequence C87436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232196
Homologene: 9897
Tmeff2
Name: transmembrane protein with EGF-like and two follistatin-like domains 2
Synonyms: 4832418D20Rik, 7630402F16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 56363
Homologene: 9417
Hoxa13
Name: homeobox A13
Synonyms: Hox-1.10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15398
HGNC: HGNC:5102
Homologene: 73882
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: Polydom, 4833413O10Rik, D430029O09Rik, 1110021D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64817
Homologene: 23386
Def6
Name: differentially expressed in FDCP 6
Synonyms: 2410003F05Rik, IBP, SLAT, IRF-4-binding protein, 6430538D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 23853
HGNC: HGNC:2760
Homologene: 11103
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Gpr98, VLGR1, Mgr1, Mass1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Slc8b1
Name: solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Synonyms: NCKX6, NCLX, Slc24a6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170756
Homologene: 41602
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12268
Homologene: 36030
Vwde
Name: von Willebrand factor D and EGF domains
Synonyms: LOC232585
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232585
Homologene: 35456
H2-T24
Name: histocompatibility 2, T region locus 24
Synonyms: H-2T24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15042
Homologene: 69019
Zfp976
Name: zinc finger protein 976
Synonyms: 9830147E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 208111
Homologene: 134004
Eme1
Name: essential meiotic structure-specific endonuclease 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268465
Homologene: 16123
Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Synonyms: NaN, NaT, SNS2, NSS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 24046
VEGA: 9
Homologene: 8041
Pde4c
Name: phosphodiesterase 4C, cAMP specific
Synonyms: E130301F19Rik, Dpde1, dunce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 110385
HGNC: HGNC:8782
Homologene: 20256
Ifit1bl1
Name: interferon induced protein with tetratricpeptide repeats 1B like 1
Synonyms: Gm14446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 667373
Homologene: 78213
Olfr644
Name: olfactory receptor 644
Synonyms: MOR13-1, GA_x6K02T2PBJ9-6803062-6802118
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259125
Homologene: 17491
AC158220.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Tmem38a
Name: transmembrane protein 38A
Synonyms: TRIC-A, 1110001E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74166
Homologene: 11449
Yod1
Name: YOD1 deubiquitinase
Synonyms: 9930028C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226418
Homologene: 13176
Olfr1265
Name: olfactory receptor 1265
Synonyms: MOR228-2, GA_x6K02T2Q125-51469027-51469956
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258340
Homologene: 133727
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 51,181,787 bp
  • C to T, chromosome 1 at 130,718,830 bp
  • A to G, chromosome 1 at 156,441,332 bp
  • T to A, chromosome 2 at 90,037,703 bp
  • T to G, chromosome 3 at 145,930,425 bp
  • T to A, chromosome 4 at 58,069,416 bp
  • T to C, chromosome 5 at 120,527,874 bp
  • A to G, chromosome 6 at 13,205,079 bp
  • CCG to CCGCG, chromosome 6 at 52,260,635 bp
  • A to G, chromosome 6 at 86,445,450 bp
  • A to C, chromosome 7 at 27,989,459 bp
  • G to A, chromosome 7 at 42,613,186 bp
  • C to T, chromosome 7 at 104,068,598 bp
  • A to G, chromosome 8 at 70,749,923 bp
  • T to A, chromosome 8 at 72,579,970 bp
  • A to G, chromosome 9 at 46,219,426 bp
  • C to T, chromosome 9 at 119,755,057 bp
  • G to A, chromosome 11 at 94,645,542 bp
  • A to G, chromosome 13 at 81,566,377 bp
  • A to G, chromosome 16 at 43,821,529 bp
  • G to A, chromosome 17 at 28,217,619 bp
  • A to G, chromosome 17 at 34,729,593 bp
  • G to T, chromosome 17 at 36,014,996 bp
  • A to G, chromosome 17 at 57,447,936 bp
  • A to G, chromosome 19 at 34,593,696 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1310 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039376-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.