Strain Name:
C57BL/6J-MtgxR1313Btlr/Mmmh
Stock Number:
039379-MU
Citation ID:
RRID:MMRRC_039379-MU
Other Names:
R1313 (G1), C57BL/6J-MtgxR1313Btlr
Major Collection:

Gene Information

Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68510
Homologene: 53111
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: C130058G22Rik, CSB, CS group B correcting gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Hnrnpul1
Name: heterogeneous nuclear ribonucleoprotein U-like 1
Synonyms: Hnrpul1, Hnrnpul, E1B-AP5, E1BAP5, E130317O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232989
Homologene: 31419
Stat1
Name: signal transducer and activator of transcription 1
Synonyms: 2010005J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20846
Homologene: 21428
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Gtf3c3
Name: general transcription factor IIIC, polypeptide 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98488
HGNC: HGNC:4666
Homologene: 40805
Clhc1
Name: clathrin heavy chain linker domain containing 1
Synonyms: 1700034F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73324
Homologene: 17569
Vav1
Name: vav 1 oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22324
Homologene: 3961
2610507B11Rik
Name: RIKEN cDNA 2610507B11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72503
Homologene: 34730
Dpyd
Name: dihydropyrimidine dehydrogenase
Synonyms: E330028L06Rik, DPD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99586
HGNC: HGNC:3012
Homologene: 85
Ogfr
Name: opioid growth factor receptor
Synonyms: 2010013E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72075
Homologene: 7199
Myo15b
Name: myosin XVB
Synonyms: E330039G21Rik, LOC217328, LOC380737
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217328
Psapl1
Name: prosaposin-like 1
Synonyms: 2310020A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76943
Homologene: 105928
Olfr473
Name: olfactory receptor 473
Synonyms: GA_x6K02T2PBJ9-10262759-10263691, MOR204-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258771
Homologene: 74116
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: Snep, 6720455I24Rik, D430044C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208777
Homologene: 14708
Lilrb4a
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4A
Synonyms: CD85K, Lilrb4, Gp49b, HM18, ILT3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14728
VEGA: 10
HGNC: HGNC:6608
Homologene: 86756
Mocs1
Name: molybdenum cofactor synthesis 1
Synonyms: 3110045D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56738
HGNC: HGNC:7190
Homologene: 4343
Ankle1
Name: ankyrin repeat and LEM domain containing 1
Synonyms: 8430438L13Rik, Ankrd41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234396
Homologene: 17562
Cep250
Name: centrosomal protein 250
Synonyms: Cep2, Inmp, B230210E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Sh3rf3
Name: SH3 domain containing ring finger 3
Synonyms: 4831416G18Rik, Sh3md4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237353
Homologene: 77551
Ddi1
Name: DNA-damage inducible 1
Synonyms: 1700011N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71829
VEGA: 9
Homologene: 100549
Rps26-ps1
Name: ribosomal protein S26, pseudogene 1
Synonyms: Gm10070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100042812
Pet112l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
C1qtnf12
Name: C1q and tumor necrosis factor related 12
Synonyms: Fam132a, C1qdc2, alipolin, 1110035L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67389
Homologene: 12123
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 52,156,006 bp
  • C to T, chromosome 1 at 54,417,778 bp
  • G to A, chromosome 1 at 93,281,654 bp
  • C to T, chromosome 2 at 155,972,079 bp
  • T to C, chromosome 2 at 180,594,630 bp
  • A to G, chromosome 3 at 85,653,826 bp
  • G to T, chromosome 3 at 118,899,161 bp
  • G to A, chromosome 4 at 155,965,874 bp
  • C to A, chromosome 5 at 36,205,266 bp
  • T to C, chromosome 5 at 139,762,906 bp
  • G to T, chromosome 7 at 25,722,916 bp
  • A to T, chromosome 7 at 107,933,768 bp
  • A to G, chromosome 8 at 71,407,213 bp
  • T to A, chromosome 8 at 107,439,457 bp
  • T to C, chromosome 9 at 6,265,769 bp
  • C to T, chromosome 10 at 51,480,736 bp
  • C to A, chromosome 10 at 59,071,999 bp
  • A to G, chromosome 11 at 29,571,678 bp
  • A to G, chromosome 11 at 78,265,672 bp
  • T to C, chromosome 11 at 115,885,129 bp
  • C to T, chromosome 14 at 32,552,720 bp
  • A to T, chromosome 17 at 49,454,269 bp
  • G to A, chromosome 17 at 57,309,498 bp
  • T to C, chromosome 18 at 49,878,483 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1313 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039379-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.