Strain Name:
C57BL/6J-MtgxR1323Btlr/Mmmh
Stock Number:
039389-MU
Citation ID:
RRID:MMRRC_039389-MU
Other Names:
R1323 (G1), C57BL/6J-MtgxR1323Btlr
Major Collection:

Gene Information

D630045J12Rik
Name: RIKEN cDNA D630045J12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330286
Homologene: 19782
Abcc8
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonyms: SUR1, Sur, D930031B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Emsy
Name: EMSY, BRCA2-interacting transcriptional repressor
Synonyms: 2210018M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233545
Homologene: 32465
Frzb
Name: frizzled-related protein
Synonyms: fritz, frzb-1, Sfrp3, Frp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20378
HGNC: HGNC:3959
Homologene: 1126
Zfp600
Name: zinc finger protein 600
Synonyms: Gm13164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 667666
Homologene: 133076
Nrbp1
Name: nuclear receptor binding protein 1
Synonyms: B230344L17Rik, Nrbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 192292
HGNC: HGNC:7993
Homologene: 8373
BC055324
Name: cDNA sequence BC055324
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381306
Homologene: 10058
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 3830402K23Rik, 4930518F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320558
Homologene: 8604
Megf8
Name: multiple EGF-like-domains 8
Synonyms: Egfl4, b2b288Clo, b2b1702Clo, m687Ddg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269878
HGNC: HGNC:3233
Homologene: 15988
Fam171a2
Name: family with sequence similarity 171, member A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217219
Homologene: 19144
Vmn2r114
Name: vomeronasal 2, receptor 114
Synonyms: EG666002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 666002
Homologene: 86604
Hnf4g
Name: hepatocyte nuclear factor 4, gamma
Synonyms: NR2A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 30942
HGNC: HGNC:5026
Homologene: 37886
Grm8
Name: glutamate receptor, metabotropic 8
Synonyms: mGluR8, Gprc1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14823
HGNC: HGNC:4600
Homologene: 654
Mtnr1b
Name: melatonin receptor 1B
Synonyms: Mel1b, Mt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244701
HGNC: HGNC:7464
Homologene: 4350
Vmn2r101
Name: vomeronasal 2, receptor 101
Synonyms: EG627576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627576
Homologene: 115024
Ankrd44
Name: ankyrin repeat domain 44
Synonyms: E130014H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329154
Homologene: 27547
Paqr5
Name: progestin and adipoQ receptor family member V
Synonyms: 0610010I15Rik, mPRg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74090
Homologene: 9788
Nckipsd
Name: NCK interacting protein with SH3 domain
Synonyms: WISH, SPIN90, AF3P21, ORF1, DIP1, Wasbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80987
Homologene: 9514
Akr1e1
Name: aldo-keto reductase family 1, member E1
Synonyms: 1810061I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56043
Homologene: 74313
Ftdc1
Name: ferritin domain containing 1
Synonyms: LOC328695, LOC385656, Gm813
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 328695
VEGA: 16
S100a14
Name: S100 calcium binding protein A14
Synonyms: 1110013O05Rik, S100a15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66166
Homologene: 10781
Elovl1
Name: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
Synonyms: Ssc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54325
Homologene: 41322
H2af-ps2
Name: H2A histone family, pseudogene 2
Synonyms: EG667728, Hist1h2al
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 667728
VEGA: 13
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 54,766,450 bp
  • C to A, chromosome 1 at 163,955,461 bp
  • G to A, chromosome 2 at 80,413,376 bp
  • G to T, chromosome 2 at 82,985,752 bp
  • A to T, chromosome 2 at 178,347,621 bp
  • T to C, chromosome 3 at 3,634,221 bp
  • T to C, chromosome 3 at 90,527,736 bp
  • T to C, chromosome 4 at 118,431,654 bp
  • A to G, chromosome 4 at 146,196,691 bp
  • T to A, chromosome 5 at 31,245,813 bp
  • A to G, chromosome 6 at 28,125,974 bp
  • T to C, chromosome 6 at 38,148,508 bp
  • T to A, chromosome 7 at 25,360,102 bp
  • T to G, chromosome 7 at 46,117,362 bp
  • T to C, chromosome 7 at 98,610,657 bp
  • A to G, chromosome 9 at 15,863,136 bp
  • C to T, chromosome 9 at 61,961,528 bp
  • G to A, chromosome 9 at 108,812,579 bp
  • C to A, chromosome 11 at 9,290,937 bp
  • T to G, chromosome 11 at 102,444,125 bp
  • C to T, chromosome 13 at 4,607,548 bp
  • T to G, chromosome 13 at 51,203,064 bp
  • G to A, chromosome 16 at 58,616,915 bp
  • G to A, chromosome 17 at 19,612,051 bp
  • ATTT to ATT, chromosome 17 at 23,290,932 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1323 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039389-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.