Strain Name:
C57BL/6J-MtgxR1339Btlr/Mmmh
Stock Number:
039404-MU
Citation ID:
RRID:MMRRC_039404-MU
Other Names:
R1339 (G1), C57BL/6J-MtgxR1339Btlr
Major Collection:

Gene Information

Adamts20
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Synonyms: ADAMTS-20, bt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223838
Homologene: 11808
Dtnbp1
Name: dystrobrevin binding protein 1
Synonyms: Bloc1s8, dysbindin, sdy, 5430437B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 94245
VEGA: 13
Homologene: 12037
Mbtd1
Name: mbt domain containing 1
Synonyms: hemp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103537
Homologene: 41185
Ubn1
Name: ubinuclein 1
Synonyms: 1110029L11Rik, 2610108L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 170644
VEGA: 16
Homologene: 9656
Foxi1
Name: forkhead box I1
Synonyms: Fkh10, Hfh3, HFH-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14233
HGNC: HGNC:3815
Homologene: 8140
Mei1
Name: meiotic double-stranded break formation protein 1
Synonyms: mei1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 74369
Homologene: 46535
Irf7
Name: interferon regulatory factor 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54123
HGNC: HGNC:6122
Homologene: 128624
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 329002
Homologene: 7198
March6
Name: membrane-associated ring finger (C3HC4) 6
Synonyms: F830029L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223455
VEGA: 15
Homologene: 4301
Rel
Name: reticuloendotheliosis oncogene
Synonyms: c-Rel
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19696
HGNC: HGNC:9954
Homologene: 2182
AC159748.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Ifi208
Name: interferon activated gene 208
Synonyms: Pydc3, Pyr-rv1, E430029J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100033459
HGNC: HGNC:5395
Homologene: 115929
Inhbc
Name: inhibin beta-C
Synonyms: activin beta-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16325
VEGA: 10
HGNC: HGNC:6068
Homologene: 21142
Shc2
Name: SHC (Src homology 2 domain containing) transforming protein 2
Synonyms: Sli, ShcB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216148
Homologene: 19127
Masp1
Name: mannan-binding lectin serine peptidase 1
Synonyms: Crarf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17174
VEGA: 16
HGNC: HGNC:6901
Homologene: 88793
Olfr13
Name: olfactory receptor 13
Synonyms: GA_x6K02T2P3E9-4384160-4383228, MOR261-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18310
Homologene: 27232
Gm15448
Name: predicted gene 15448
Synonyms: ENSMUSG00000074419
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100041146
HGNC: HGNC:6607
Homologene: 134028
Cyp4a32
Name: cytochrome P450, family 4, subfamily a, polypeptide 32
Synonyms: OTTMUSG00000008689
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100040843
HGNC: HGNC:2642
Homologene: 128044
4921517D22Rik
Name: RIKEN cDNA 4921517D22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 70900
VEGA: 13
Homologene: 87278
Cplane2
Name: ciliogenesis and planar polarity effector 2
Synonyms: LOC279260, Rsg1, b2b2804Clo, b2b2827Clo, 6330545A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76166
Homologene: 12793
Olfr421-ps1
Name: olfactory receptor 421, pseudogene 1
Synonyms: GA_x6K02T2P20D-21002372-21001425, Olfr421, GA_x6K02T2P20D-21006310-21006124, Olfr422-ps1, MOR105-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258715
Gm2058
Name: predicted gene 2058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100039133
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 173,683,238 bp
  • G to T, chromosome 1 at 174,152,211 bp
  • A to G, chromosome 4 at 115,611,563 bp
  • A to G, chromosome 4 at 141,218,548 bp
  • G to C, chromosome 6 at 43,174,610 bp
  • A to G, chromosome 7 at 3,822,156 bp
  • T to C, chromosome 7 at 39,589,123 bp
  • G to A, chromosome 7 at 141,263,704 bp
  • G to A, chromosome 10 at 5,367,571 bp
  • T to G, chromosome 10 at 79,626,416 bp
  • C to A, chromosome 10 at 127,357,641 bp
  • C to T, chromosome 11 at 23,745,763 bp
  • T to C, chromosome 11 at 34,205,866 bp
  • T to G, chromosome 11 at 93,925,662 bp
  • G to A, chromosome 13 at 44,923,220 bp
  • GCC to GC, chromosome 13 at 59,691,598 bp
  • T to C, chromosome 15 at 31,486,402 bp
  • A to G, chromosome 15 at 82,081,995 bp
  • A to T, chromosome 15 at 94,322,896 bp
  • A to G, chromosome 16 at 5,055,335 bp
  • C to A, chromosome 16 at 23,452,467 bp
  • T to C, chromosome 18 at 82,657,989 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1339 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039404-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.