Strain Name:
C57BL/6J-MtgxR1355Btlr/Mmmh
Stock Number:
039420-MU
Citation ID:
RRID:MMRRC_039420-MU
Other Names:
R1355 (G1), C57BL/6J-MtgxR1355Btlr
Major Collection:

Gene Information

Itgb8
Name: integrin beta 8
Synonyms: 4832412O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320910
HGNC: HGNC:6163
Homologene: 18567
Rgs16
Name: regulator of G-protein signaling 16
Synonyms: Rgsr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19734
HGNC: HGNC:9997
Homologene: 2196
Cryzl1
Name: crystallin, zeta (quinone reductase)-like 1
Synonyms: 2410006O11Rik, 2210407J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66609
HGNC: HGNC:2420
Homologene: 3749
Ppp4r1
Name: protein phosphatase 4, regulatory subunit 1
Synonyms: 3110001J10Rik, Pp4r1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70351
HGNC: HGNC:9320
Homologene: 81737
Prdm2
Name: PR domain containing 2, with ZNF domain
Synonyms: 4833427P12Rik, KMT8, E330024L24Rik, LOC381568, Riz1, Riz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 110593
HGNC: HGNC:9347
Homologene: 40822
Usp38
Name: ubiquitin specific peptidase 38
Synonyms: 4631402N15Rik, 4833420O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74841
Homologene: 12367
Sik3
Name: SIK family kinase 3
Synonyms: 9030204A07Rik, 5730525O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70661
Homologene: 57023
Ttc3
Name: tetratricopeptide repeat domain 3
Synonyms: 2610202A04Rik, D16Ium21e, D16Ium21, TPRD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22129
Homologene: 2487
Plxna1
Name: plexin A1
Synonyms: PlexA1, Plxn1, 2600013D04Rik, NOV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18844
HGNC: HGNC:9099
Homologene: 56426
Rer1
Name: retention in endoplasmic reticulum sorting receptor 1
Synonyms: 1110060F11Rik, 5830454N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67830
Homologene: 5468
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21844
Homologene: 2443
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: 2610301F02Rik, ENSMUSG00000075261, CAMDI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545428
Homologene: 52149
Sgo2a
Name: shugoshin 2A
Synonyms: Sgol2, 1110007N04Rik, 5730576N04Rik, Tripin, Sgol2a, D1Ertd8e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68549
Homologene: 51867
Erc1
Name: ELKS/RAB6-interacting/CAST family member 1
Synonyms: Elks1, RAB6IP2A, RAB6IP2B, B430107L16Rik, 9630025C19Rik, Rab6ip2, 5033405M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 111173
Homologene: 14229
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: Coh1, C330002D13Rik, 1810042B05Rik, 2310042E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Susd1
Name: sushi domain containing 1
Synonyms: Gm12528
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 634731
Homologene: 11204
Pros1
Name: protein S (alpha)
Synonyms: protein S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19128
HGNC: HGNC:9456
Homologene: 264
Hs6st1
Name: heparan sulfate 6-O-sulfotransferase 1
Synonyms: 6OST1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 50785
HGNC: HGNC:5201
Homologene: 75051
Wasf3
Name: WAS protein family, member 3
Synonyms: Wave3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 245880
Homologene: 68527
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: LOC224126, Hapip, E530005C20Rik, 2210407G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Dpy19l4
Name: dpy-19-like 4 (C. elegans)
Synonyms: Narg3, LOC381510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381510
Homologene: 18773
Slc44a3
Name: solute carrier family 44, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213603
Homologene: 64830
Uckl1
Name: uridine-cytidine kinase 1-like 1
Synonyms: 1110007H10Rik, Urkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68556
Homologene: 101414
Ankrd52
Name: ankyrin repeat domain 52
Synonyms: G431002C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237615
Homologene: 18227
Vwa3a
Name: von Willebrand factor A domain containing 3A
Synonyms: E030013G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233813
Homologene: 18607
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: PYPAF2, Nalp2, E330007A02Rik, Nbs1, Pan1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232827
Homologene: 56789
Arhgef5
Name: Rho guanine nucleotide exchange factor (GEF) 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54324
Homologene: 66300
Ccdc146
Name: coiled-coil domain containing 146
Synonyms: 4930528G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75172
Homologene: 67159
Atp10b
Name: ATPase, class V, type 10B
Synonyms: 5930426O13Rik, 9030605H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319767
Homologene: 70969
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 333315
Homologene: 35388
Dennd3
Name: DENN/MADD domain containing 3
Synonyms: E030003N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105841
Homologene: 28254
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: C230094A16Rik, 2900083P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237711
Homologene: 104282
Cebpz
Name: CCAAT/enhancer binding protein zeta
Synonyms: Cebpa-rs1, Cbf, CBF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12607
VEGA: 17
Homologene: 4210
Olfr144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: 4930415K13Rik, Rgsl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240816
Homologene: 129962
Cd226
Name: CD226 antigen
Synonyms: Pta1, DNAM1, DNAM-1, TLiSA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225825
Homologene: 4787
Gm1110
Name: predicted gene 1110
Synonyms: LOC382064
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382064
VEGA: 9
Homologene: 78608
Ism1
Name: isthmin 1, angiogenesis inhibitor
Synonyms: 5430433G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319909
Homologene: 19061
Gm10288
Name: predicted gene 10288
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100040540
Lrrcc1
Name: leucine rich repeat and coiled-coil domain containing 1
Synonyms: 1200008A14Rik, 4932441F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71710
Homologene: 12559
Abcb10
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 10
Synonyms: ABC-me
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56199
HGNC: HGNC:41
Homologene: 6474
Setdb2
Name: SET domain, bifurcated 2
Synonyms: KMT1F, LOC239122
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239122
Homologene: 12903
H2bc13
Name: H2B clustered histone 13
Synonyms: Hist1h2bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319185
HGNC: HGNC:4753
Homologene: 136773
Snrpd1
Name: small nuclear ribonucleoprotein D1
Synonyms: SMD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20641
VEGA: 18
Homologene: 107532
B4galnt4
Name: beta-1,4-N-acetyl-galactosaminyl transferase 4
Synonyms: LOC381951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330671
Homologene: 27982
Cyp2c68
Name: cytochrome P450, family 2, subfamily c, polypeptide 68
Synonyms: 9030012A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433247
Homologene: 74936
Soga3
Name: SOGA family member 3
Synonyms: 6330407J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67412
VEGA: 10
Homologene: 28227
Olfr140
Name: olfactory receptor 140
Synonyms: A16, GA_x6K02T2Q125-51484508-51483600, MOR235-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57272
Homologene: 41379
Olfr1466
Name: olfactory receptor 1466
Synonyms: GA_x6K02T2RE5P-3672907-3673839, MOR202-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258689
Homologene: 133677
Mettl5
Name: methyltransferase like 5
Synonyms: 2810410A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75422
Homologene: 8570
Ccne1
Name: cyclin E1
Synonyms: cyclin E, CycE1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12447
HGNC: HGNC:1589
Homologene: 14452
Fam71e1
Name: family with sequence similarity 71, member E1
Synonyms: 0610007G24Rik, 1700021N13Rik, 1700021P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75538
Homologene: 19259
Gm11937
Name: predicted gene 11937
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100041488
Homologene: 41961
Olfr198
Name: olfactory receptor 198
Synonyms: GA_x54KRFPKG5P-55416332-55415412, MOR182-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258036
Homologene: 51800
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 36,103,576 bp
  • A to G, chromosome 1 at 58,017,965 bp
  • A to T, chromosome 1 at 153,743,668 bp
  • A to G, chromosome 1 at 153,807,761 bp
  • A to T, chromosome 2 at 69,881,420 bp
  • A to T, chromosome 2 at 77,030,601 bp
  • G to A, chromosome 2 at 90,051,613 bp
  • A to T, chromosome 2 at 139,732,074 bp
  • G to T, chromosome 2 at 181,573,376 bp
  • G to T, chromosome 3 at 14,548,114 bp
  • C to A, chromosome 3 at 121,531,671 bp
  • A to T, chromosome 3 at 146,838,993 bp
  • C to T, chromosome 4 at 11,303,371 bp
  • C to T, chromosome 4 at 59,424,114 bp
  • C to T, chromosome 4 at 143,131,963 bp
  • T to A, chromosome 4 at 155,075,624 bp
  • A to T, chromosome 5 at 21,321,242 bp
  • T to C, chromosome 5 at 146,470,208 bp
  • T to A, chromosome 6 at 43,283,912 bp
  • T to A, chromosome 6 at 48,448,626 bp
  • A to G, chromosome 6 at 89,320,766 bp
  • A to T, chromosome 6 at 119,743,420 bp
  • G to T, chromosome 7 at 5,327,491 bp
  • A to G, chromosome 7 at 38,106,322 bp
  • A to G, chromosome 7 at 44,496,691 bp
  • A to G, chromosome 7 at 120,784,111 bp
  • T to C, chromosome 7 at 141,065,395 bp
  • A to G, chromosome 8 at 80,690,702 bp
  • T to C, chromosome 8 at 80,985,033 bp
  • C to T, chromosome 8 at 123,962,052 bp
  • T to A, chromosome 9 at 26,883,761 bp
  • G to C, chromosome 9 at 39,238,251 bp
  • C to T, chromosome 9 at 46,195,872 bp
  • A to T, chromosome 10 at 29,147,322 bp
  • A to G, chromosome 10 at 128,388,696 bp
  • T to G, chromosome 11 at 29,833,085 bp
  • G to A, chromosome 11 at 43,151,655 bp
  • A to T, chromosome 11 at 99,609,907 bp
  • C to T, chromosome 12 at 119,171,003 bp
  • T to A, chromosome 13 at 21,715,857 bp
  • T to A, chromosome 14 at 59,417,441 bp
  • C to T, chromosome 15 at 35,422,454 bp
  • A to C, chromosome 15 at 73,540,854 bp
  • T to A, chromosome 16 at 33,975,584 bp
  • A to G, chromosome 16 at 59,201,680 bp
  • A to G, chromosome 16 at 62,919,558 bp
  • A to T, chromosome 16 at 89,898,221 bp
  • A to G, chromosome 16 at 91,692,658 bp
  • A to G, chromosome 16 at 94,418,637 bp
  • A to T, chromosome 17 at 65,840,987 bp
  • G to T, chromosome 17 at 78,935,324 bp
  • G to A, chromosome 18 at 10,627,818 bp
  • T to A, chromosome 18 at 89,247,023 bp
  • T to A, chromosome 19 at 13,342,518 bp
  • A to G, chromosome 19 at 39,740,956 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1355 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039420-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.