Strain Name:
C57BL/6J-MtgxR1394Btlr/Mmmh
Stock Number:
039456-MU
Citation ID:
RRID:MMRRC_039456-MU
Other Names:
R1394 (G1), C57BL/6J-MtgxR1394Btlr
Major Collection:

Gene Information

Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Mkks
Name: McKusick-Kaufman syndrome
Synonyms: 1300013E18Rik, Bbs6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59030
HGNC: HGNC:7108
Homologene: 10318
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72313
Homologene: 103956
Cep290
Name: centrosomal protein 290
Synonyms: Nphp6, b2b1454Clo, b2b1752Clo, Kiaa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216274
VEGA: 10
Homologene: 77213
Wdr44
Name: WD repeat domain 44
Synonyms: DKFZp686L20145, RAB11BP, RPH11, 2610034K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 72404
Homologene: 56839
Fkbp15
Name: FK506 binding protein 15
Synonyms: FKBP133, C430014M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 338355
Homologene: 28743
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, dynein heavy chain, retrograde transport, Dnec1, Loa, 9930018I23Rik, Dnchc1, Swl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Gtf3c3
Name: general transcription factor IIIC, polypeptide 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98488
HGNC: HGNC:4666
Homologene: 40805
Ankrd27
Name: ankyrin repeat domain 27 (VPS9 domain)
Synonyms: D330003H11Rik, Varp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 245886
Homologene: 12956
Cep128
Name: centrosomal protein 128
Synonyms: 5430424K18Rik, 4930534B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75216
Homologene: 35315
Psen1
Name: presenilin 1
Synonyms: S182, PS1, PS-1, presenilin-1, Ad3h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19164
VEGA: 12
HGNC: HGNC:9508
Homologene: 7186
Scyl2
Name: SCY1-like 2 (S. cerevisiae)
Synonyms: D10Ertd802e, CVAK104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213326
Homologene: 13349
C2cd5
Name: C2 calcium-dependent domain containing 5
Synonyms: C030008B15Rik, CDP138, 5730419I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74741
Homologene: 8873
Mybbp1a
Name: MYB binding protein (P160) 1a
Synonyms: p67MBP, p160MBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18432
HGNC: HGNC:7546
Homologene: 40954
Kank1
Name: KN motif and ankyrin repeat domains 1
Synonyms: D330024H06Rik, A930031B09Rik, Ankrd15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107351
Homologene: 17706
Zfy1
Name: zinc finger protein 1, Y-linked
Synonyms: Zfy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22767
Homologene: 56456
Spin1
Name: spindlin 1
Synonyms: Spin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20729
VEGA: 13
Homologene: 55983
Ift81
Name: intraflagellar transport 81
Synonyms: CDV-1R, Cdv1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12589
Homologene: 7664
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
2900026A02Rik
Name: RIKEN cDNA 2900026A02 gene
Synonyms: LOC231620, Gm449
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243219
Homologene: 129566
Cwc22
Name: CWC22 spliceosome-associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 80744
Homologene: 6048
Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Synonyms: Plekhe1, Phlpp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98432
Homologene: 11015
Pcdh12
Name: protocadherin 12
Synonyms: VE-cadherin-2, vascular endothelial cadherin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 53601
HGNC: HGNC:8657
Homologene: 9574
Vasn
Name: vasorin
Synonyms: 2610528G05Rik, Slitl2, ATIA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 246154
Homologene: 36929
Ift172
Name: intraflagellar transport 172
Synonyms: wim, 4930553F24Rik, avc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67661
Homologene: 15202
Cep192
Name: centrosomal protein 192
Synonyms: D430014P18Rik, 4631422C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70799
VEGA: 18
Homologene: 73526
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: lrd, b2b598Clo, b2b1289Clo, b2b1727Clo, b2b1279Clo, b2b1203Clo, Dnahc11, avc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: basilin, FOAP-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
Drc3
Name: dynein regulatory complex subunit 3
Synonyms: 4930449E07Rik, Lrrc48, m6Bei
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74665
Homologene: 12581
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Tppp2
Name: tubulin polymerization-promoting protein family member 2
Synonyms: LOC219038, LOC386487
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219038
VEGA: 14
Homologene: 25079
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 211223
Homologene: 129606
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
Phlpp2
Name: PH domain and leucine rich repeat protein phosphatase 2
Synonyms: C130044A18Rik, Phlppl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244650
Homologene: 71015
Spata46
Name: spermatogenesis associated 46
Synonyms: 1700015E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76925
Homologene: 18799
Tecpr1
Name: tectonin beta-propeller repeat containing 1
Synonyms: 2210010N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70381
Homologene: 9120
Prickle2
Name: prickle planar cell polarity protein 2
Synonyms: 6720451F06Rik, 6230400G14Rik, mpk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243548
Homologene: 17889
Psg19
Name: pregnancy specific beta-1-glycoprotein 19
Synonyms: CGM7, Cea-4, Cea4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26439
Homologene: 110989
Rgma
Name: repulsive guidance molecule family member A
Synonyms: RGM domain family, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244058
Homologene: 10626
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: 6720455I24Rik, Snep, D430044C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208777
Homologene: 14708
Or6z6
Name: olfactory receptor family 6 subfamily Z member 6
Synonyms: GA_x6K02T2QGBW-3218686-3217748, MOR103-11, MOR103-19_i, Olfr1347
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258383
Homologene: 128065
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 215384
Homologene: 68369
Obsl1
Name: obscurin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98733
Gm597
Name: predicted gene 597
Synonyms: LOC210962
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210962
Ipp
Name: IAP promoted placental gene
Synonyms: D4Jhu8, Mipp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16351
HGNC: HGNC:6108
Homologene: 4309
Casd1
Name: CAS1 domain containing 1
Synonyms: Cast1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213819
Homologene: 11287
Itm2a
Name: integral membrane protein 2A
Synonyms: Itm2, Bricd2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 16431
HGNC: HGNC:6173
Homologene: 31269
Zfand1
Name: zinc finger, AN1-type domain 1
Synonyms: 2310008M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66361
Homologene: 6779
Rdh12
Name: retinol dehydrogenase 12
Synonyms: A930033N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77974
Homologene: 110830
Or9s13
Name: olfactory receptor family 9 subfamily S member 13
Synonyms: MOR208-5, GA_x6K02T2R7CC-81134096-81133095, Olfr12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 257890
Homologene: 114777
Cyp4a30b
Name: cytochrome P450, family 4, subfamily a, polypeptide 30b
Synonyms: OTTMUSG00000008626, Cyp4a30b-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435802
A330070K13Rik
Name: RIKEN cDNA A330070K13 gene
Synonyms: LOC381673
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381673
Klrb1b
Name: killer cell lectin-like receptor subfamily B member 1B
Synonyms: Nkrp1-b, NKR-P1D, Ly55d, Ly55b, Nkrp1d, NKR-P1B, Klrb1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 80782
HGNC: HGNC:6373
Homologene: 84369
Ptgr2
Name: prostaglandin reductase 2
Synonyms: B830026H24Rik, 9630002F03Rik, 1810016I24Rik, PGR-2, Zadh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77219
Homologene: 39824
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 28,776,809 bp
  • T to C, chromosome 1 at 34,165,155 bp
  • A to G, chromosome 1 at 45,403,419 bp
  • C to T, chromosome 1 at 54,417,778 bp
  • T to C, chromosome 1 at 75,492,665 bp
  • T to A, chromosome 1 at 92,620,545 bp
  • G to A, chromosome 1 at 93,281,654 bp
  • T to C, chromosome 1 at 106,350,618 bp
  • A to G, chromosome 1 at 170,312,004 bp
  • G to A, chromosome 2 at 77,929,479 bp
  • C to T, chromosome 2 at 136,880,962 bp
  • G to T, chromosome 3 at 10,346,209 bp
  • T to A, chromosome 4 at 62,327,872 bp
  • A to T, chromosome 4 at 115,470,892 bp
  • T to A, chromosome 4 at 116,537,912 bp
  • T to C, chromosome 5 at 31,285,238 bp
  • T to C, chromosome 5 at 73,072,912 bp
  • T to A, chromosome 5 at 109,294,148 bp
  • A to G, chromosome 5 at 113,101,496 bp
  • G to T, chromosome 5 at 122,568,923 bp
  • A to G, chromosome 5 at 130,379,141 bp
  • T to C, chromosome 5 at 144,206,539 bp
  • T to G, chromosome 6 at 4,624,117 bp
  • T to A, chromosome 6 at 92,376,382 bp
  • G to A, chromosome 6 at 128,820,330 bp
  • T to C, chromosome 6 at 143,061,738 bp
  • T to A, chromosome 7 at 6,488,362 bp
  • T to C, chromosome 7 at 18,797,058 bp
  • A to G, chromosome 7 at 28,093,379 bp
  • T to C, chromosome 7 at 35,615,869 bp
  • G to T, chromosome 7 at 73,417,794 bp
  • T to A, chromosome 8 at 48,276,400 bp
  • T to A, chromosome 8 at 109,877,030 bp
  • T to A, chromosome 10 at 89,640,965 bp
  • T to C, chromosome 10 at 100,537,529 bp
  • T to C, chromosome 11 at 60,393,719 bp
  • C to T, chromosome 11 at 72,443,648 bp
  • A to G, chromosome 12 at 79,209,065 bp
  • G to A, chromosome 12 at 83,724,572 bp
  • T to C, chromosome 12 at 84,296,223 bp
  • C to T, chromosome 12 at 91,266,980 bp
  • G to A, chromosome 12 at 110,636,509 bp
  • T to C, chromosome 12 at 117,972,364 bp
  • T to C, chromosome 13 at 51,144,481 bp
  • A to G, chromosome 14 at 51,919,332 bp
  • C to T, chromosome 16 at 4,649,712 bp
  • A to G, chromosome 17 at 33,583,740 bp
  • G to T, chromosome 17 at 71,253,071 bp
  • A to G, chromosome 18 at 38,281,189 bp
  • A to G, chromosome 18 at 67,858,921 bp
  • A to G, chromosome 19 at 25,428,164 bp
  • T to G, chromosome X at 23,796,059 bp
  • C to T, chromosome X at 107,398,201 bp
  • C to T, chromosome Y at 725,957 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1394 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039456-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.