Strain Name:
C57BL/6J-MtgxR1398Btlr/Mmmh
Stock Number:
039460-MU
Citation ID:
RRID:MMRRC_039460-MU
Other Names:
R1398 (G1), C57BL/6J-MtgxR1398Btlr
Major Collection:

Gene Information

Uso1
Name: USO1 vesicle docking factor
Synonyms: TAP, Vdp, transcytosis associated protein p115
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56041
Homologene: 2754
Cadps
Name: Ca2+-dependent secretion activator
Synonyms: CAPS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 27062
VEGA: 14
HGNC: HGNC:1426
Homologene: 2755
Rtel1
Name: regulator of telomere elongation helicase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269400
Homologene: 13168
Lrig3
Name: leucine-rich repeats and immunoglobulin-like domains 3
Synonyms: 9430095K15Rik, 9030421L11Rik, 9130004I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 320398
VEGA: 10
Homologene: 62452
Syngr3
Name: synaptogyrin 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20974
Homologene: 3101
Kif4
Name: kinesin family member 4
Synonyms: N-5 kinesin, Kns4, D330050K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 16571
Homologene: 69022
Wdr70
Name: WD repeat domain 70
Synonyms: 4833422F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 545085
VEGA: 15
Homologene: 9972
Rps6kc1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: B130003F20Rik, RPK118
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 320119
Homologene: 8244
Mtbp
Name: Mdm2, transformed 3T3 cell double minute p53 binding protein
Synonyms: MDM2BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105837
HGNC: HGNC:7417
Homologene: 11102
Uvrag
Name: UV radiation resistance associated gene
Synonyms: 9530039D02Rik, Uvragl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78610
Homologene: 31150
Nvl
Name: nuclear VCP-like
Synonyms: 1200009I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67459
HGNC: HGNC:8070
Homologene: 1902
Ehd4
Name: EH-domain containing 4
Synonyms: 2210022F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98878
HGNC: HGNC:3245
Homologene: 26430
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Zdhhc13
Name: zinc finger, DHHC domain containing 13
Synonyms: kojak, skc4, Hip14l, 2410004E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243983
Homologene: 75106
Nectin3
Name: nectin cell adhesion molecule 3
Synonyms: Pvrl3, 2610301B19Rik, 4921513D19Rik, 3000002N23Rik, nectin-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 58998
Homologene: 9162
Ldlr
Name: low density lipoprotein receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16835
VEGA: 9
HGNC: HGNC:6547
Homologene: 55469
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: hyrt, 2310001H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67095
Homologene: 25103
Sox8
Name: SRY (sex determining region Y)-box 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20681
Homologene: 7950
Lepr
Name: leptin receptor
Synonyms: Leprb, LEPROT, Modb1, OB-RGRP, leptin receptor gene-related protein, obl, obese-like, Obr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16847
HGNC: HGNC:6554
Homologene: 1731
Zdhhc18
Name: zinc finger, DHHC domain containing 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 503610
Homologene: 110918
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Ncam1
Name: neural cell adhesion molecule 1
Synonyms: CD56, NCAM-120, NCAM-140, NCAM-180, NCAM, E-NCAM, NCAM-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17967
HGNC: HGNC:7656
Homologene: 40754
Smc6
Name: structural maintenance of chromosomes 6
Synonyms: 2810489L22Rik, Smc6l1, 3830418C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 67241
VEGA: 12
Homologene: 41575
Abca17
Name: ATP-binding cassette, sub-family A (ABC1), member 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381072
Homologene: 86807
Cep63
Name: centrosomal protein 63
Synonyms: ET2, D9Mgc41, CD20R, D9Mgc48e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 28135
Homologene: 11861
Dpy19l2
Name: dpy-19-like 2 (C. elegans)
Synonyms: 4932443J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320752
VEGA: 9
Homologene: 77569
Fgfrl1
Name: fibroblast growth factor receptor-like 1
Synonyms: FGFR5, FGFR5beta, fibroblast growth factor receptor 5, FGFR5gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 116701
HGNC: HGNC:3693
Homologene: 11067
Nrros
Name: negative regulator of reactive oxygen species
Synonyms: E430025L02Rik, Lrrc33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224109
Homologene: 17134
Pms1
Name: PMS1 homolog 1, mismatch repair system component
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227099
HGNC: HGNC:9121
Homologene: 449
Eme2
Name: essential meiotic structure-specific endonuclease subunit 2
Synonyms: 2810013J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 193838
Homologene: 19180
Ppp1r21
Name: protein phosphatase 1, regulatory subunit 21
Synonyms: Ccdc128, 1110018J12Rik, Klraq1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73825
Homologene: 44811
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, Hapip, E530005C20Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Robo4
Name: roundabout guidance receptor 4
Synonyms: 1200012D01Rik, Magic roundabout
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74144
Homologene: 10397
Eif4e
Name: eukaryotic translation initiation factor 4E
Synonyms: If4e, eIF-4E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 13684
HGNC: HGNC:3287
Homologene: 123817
Hoxa13
Name: homeobox A13
Synonyms: Hox-1.10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 15398
HGNC: HGNC:5102
Homologene: 73882
Sec31b
Name: Sec31 homolog B (S. cerevisiae)
Synonyms: Sec31l2, LOC240667
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240667
Homologene: 56708
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: b2b1289Clo, b2b1727Clo, b2b598Clo, lrd, b2b1203Clo, b2b1279Clo, avc4, Dnahc11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Fam160b1
Name: family with sequence similarity 160, member B1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226252
VEGA: 19
Homologene: 28133
Polq
Name: polymerase (DNA directed), theta
Synonyms: A430110D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 77782
HGNC: HGNC:9186
Homologene: 32727
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22371
Homologene: 466
4931408C20Rik
Name: RIKEN cDNA 4931408C20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 210940
Homologene: 86827
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242627
Homologene: 135888
Scn9a
Name: sodium channel, voltage-gated, type IX, alpha
Synonyms: PN1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20274
Homologene: 2237
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: Myhsf1, Myhs-f1, MyHC-IIa, MHC2A, Myhs-f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
9330182L06Rik
Name: RIKEN cDNA 9330182L06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231014
Homologene: 27396
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12268
Homologene: 36030
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Rev, Sez4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Yipf3
Name: Yip1 domain family, member 3
Synonyms: D17Wsu94e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 28064
Homologene: 9117
Aldh3a2
Name: aldehyde dehydrogenase family 3, subfamily A2
Synonyms: Aldh4, Ahd-3, Ahd-3r, FALDH, Ahd3, Aldh4-r, Ahd3-r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11671
HGNC: HGNC:403
Homologene: 55458
AC132131.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Kctd1
Name: potassium channel tetramerisation domain containing 1
Synonyms: 4933402K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106931
VEGA: 18
Homologene: 65999
Lgals12
Name: lectin, galactose binding, soluble 12
Synonyms: galectin-related inhibitor of proliferation, GRIP1, galectin-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56072
Homologene: 10462
Olfr495
Name: olfactory receptor 495
Synonyms: GA_x6K02T2PBJ9-10725148-10726140, MOR204-37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258361
Homologene: 133600
Gmcl1
Name: germ cell-less, spermatogenesis associated 1
Synonyms: mglc-1, Gcl, 2810049L19Rik, Btbd13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23885
Homologene: 8021
Gm4922
Name: predicted gene 4922
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237300
VEGA: 10
Homologene: 50497
Cacna2d1
Name: calcium channel, voltage-dependent, alpha2/delta subunit 1
Synonyms: Cchl2a, Ca(v)alpha2delta1, Cacna2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12293
HGNC: HGNC:1399
Homologene: 579
Lrrc4b
Name: leucine rich repeat containing 4B
Synonyms: Lrig4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 272381
Homologene: 45681
Slfn1
Name: schlafen 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20555
Homologene: 86967
Isg20l2
Name: interferon stimulated exonuclease gene 20-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229504
Homologene: 12814
Grsf1
Name: G-rich RNA sequence binding factor 1
Synonyms: D5Wsu31e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231413
HGNC: HGNC:4610
Homologene: 20482
Dsc1
Name: desmocollin 1
Synonyms: Dsc1a, Dsc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13505
VEGA: 18
HGNC: HGNC:3035
Homologene: 22761
Kcnk10
Name: potassium channel, subfamily K, member 10
Synonyms: 1700024D23Rik, Trek2, 3010005K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 72258
VEGA: 12
HGNC: HGNC:6273
Homologene: 11321
Cyp2c67
Name: cytochrome P450, family 2, subfamily c, polypeptide 67
Synonyms: C730004C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 545288
Homologene: 74936
Anks6
Name: ankyrin repeat and sterile alpha motif domain containing 6
Synonyms: Samd6, 2210417J20Rik, LOC269533, SamCystin, b2b1801.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75691
Homologene: 19545
Bdh2
Name: 3-hydroxybutyrate dehydrogenase, type 2
Synonyms: 1810026B04Rik, Dhrs6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69772
Homologene: 134268
Slc22a28
Name: solute carrier family 22, member 28
Synonyms: Gm5631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 434674
VEGA: 19
Homologene: 77136
March2
Name: membrane-associated ring finger (C3HC4) 2
Synonyms: 9530046H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224703
Homologene: 9539
Heatr4
Name: HEAT repeat containing 4
Synonyms: Gm17673
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 101055670
Homologene: 45728
Krtap4-1
Name: keratin associated protein 4-1
Synonyms: A030010K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 665891
Cnot11
Name: CCR4-NOT transcription complex, subunit 11
Synonyms: 2410015L18Rik, D1Bwg0212e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 52846
Homologene: 9711
Chil4
Name: chitinase-like 4
Synonyms: Ym2, Chi3l4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 104183
Homologene: 74931
Dctn5
Name: dynactin 5
Synonyms: p25 dynactin subunit, b2b315Clo, 4930427E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 59288
Homologene: 10998
Gm3159
Name: predicted gene 3159
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100041139
Homologene: 115686
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 26,685,341 bp
  • A to G, chromosome 1 at 39,545,180 bp
  • A to T, chromosome 1 at 53,207,276 bp
  • A to T, chromosome 1 at 181,097,126 bp
  • T to C, chromosome 1 at 190,800,015 bp
  • T to A, chromosome 2 at 52,289,646 bp
  • A to G, chromosome 2 at 66,484,586 bp
  • A to T, chromosome 2 at 120,127,600 bp
  • T to A, chromosome 2 at 181,335,865 bp
  • C to A, chromosome 3 at 87,938,754 bp
  • T to A, chromosome 3 at 106,219,509 bp
  • T to C, chromosome 3 at 135,295,296 bp
  • A to T, chromosome 3 at 138,546,375 bp
  • T to A, chromosome 4 at 47,044,926 bp
  • T to A, chromosome 4 at 101,792,019 bp
  • T to C, chromosome 4 at 113,779,071 bp
  • G to C, chromosome 4 at 133,627,297 bp
  • A to T, chromosome 4 at 145,099,983 bp
  • A to G, chromosome 5 at 9,380,297 bp
  • G to A, chromosome 5 at 16,357,766 bp
  • A to G, chromosome 5 at 88,665,847 bp
  • C to T, chromosome 5 at 92,181,468 bp
  • T to A, chromosome 5 at 108,706,281 bp
  • C to G, chromosome 6 at 52,260,647 bp
  • G to C, chromosome 6 at 52,260,648 bp
  • G to A, chromosome 6 at 86,714,262 bp
  • A to T, chromosome 6 at 125,603,457 bp
  • A to C, chromosome 7 at 44,462,452 bp
  • G to A, chromosome 7 at 48,826,873 bp
  • G to T, chromosome 7 at 99,065,820 bp
  • T to A, chromosome 7 at 108,395,501 bp
  • T to C, chromosome 7 at 122,145,941 bp
  • A to T, chromosome 9 at 21,739,542 bp
  • T to A, chromosome 9 at 24,581,263 bp
  • T to C, chromosome 9 at 37,408,076 bp
  • G to A, chromosome 9 at 49,517,589 bp
  • A to T, chromosome 9 at 102,603,086 bp
  • C to T, chromosome 9 at 121,454,359 bp
  • T to A, chromosome 10 at 18,783,748 bp
  • T to A, chromosome 10 at 39,821,583 bp
  • A to G, chromosome 10 at 90,050,029 bp
  • C to T, chromosome 10 at 126,003,088 bp
  • T to C, chromosome 11 at 61,256,736 bp
  • C to T, chromosome 11 at 67,185,287 bp
  • T to A, chromosome 11 at 83,121,142 bp
  • T to C, chromosome 11 at 99,627,732 bp
  • T to C, chromosome 12 at 11,271,879 bp
  • T to A, chromosome 12 at 83,967,621 bp
  • C to A, chromosome 12 at 98,436,226 bp
  • T to A, chromosome 12 at 118,057,106 bp
  • T to A, chromosome 14 at 4,398,586 bp
  • G to T, chromosome 14 at 12,449,822 bp
  • T to A, chromosome 15 at 8,035,844 bp
  • C to A, chromosome 15 at 55,577,537 bp
  • A to G, chromosome 16 at 18,781,971 bp
  • A to T, chromosome 16 at 32,143,144 bp
  • A to G, chromosome 16 at 34,212,820 bp
  • T to A, chromosome 16 at 37,062,495 bp
  • A to G, chromosome 16 at 46,448,756 bp
  • T to C, chromosome 17 at 24,328,537 bp
  • C to A, chromosome 17 at 24,686,440 bp
  • G to A, chromosome 17 at 24,892,918 bp
  • T to C, chromosome 17 at 25,567,883 bp
  • T to C, chromosome 17 at 33,696,122 bp
  • T to A, chromosome 17 at 34,730,719 bp
  • T to C, chromosome 17 at 46,251,446 bp
  • T to C, chromosome 17 at 88,542,879 bp
  • T to C, chromosome 18 at 15,062,597 bp
  • A to T, chromosome 18 at 20,088,336 bp
  • C to T, chromosome 19 at 7,603,957 bp
  • G to T, chromosome 19 at 8,130,202 bp
  • A to G, chromosome 19 at 39,638,625 bp
  • T to A, chromosome 19 at 44,523,665 bp
  • T to A, chromosome 19 at 57,372,926 bp
  • G to T, chromosome X at 100,689,097 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1398 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039460-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.