Strain Name:
C57BL/6J-MtgxR1439Btlr/Mmmh
Stock Number:
039494-MU
Citation ID:
RRID:MMRRC_039494-MU
Other Names:
R1439 (G1), C57BL/6J-MtgxR1439Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22288
VEGA: 10
Homologene: 21398
Itga6
Name: integrin alpha 6
Synonyms: Cd49f, 5033401O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16403
HGNC: HGNC:6142
Homologene: 20091
Ntrk1
Name: neurotrophic tyrosine kinase, receptor, type 1
Synonyms: Tkr, TrkA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18211
HGNC: HGNC:8031
Homologene: 1898
Ep400
Name: E1A binding protein p400
Synonyms: 1700020J09Rik, mDomino, p400
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 75560
Homologene: 38779
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, 2810012K13Rik, SBP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75420
Homologene: 11415
Fubp3
Name: far upstream element (FUSE) binding protein 3
Synonyms: A330051M14Rik, Marta2, FBP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320267
HGNC: HGNC:4005
Homologene: 45954
Agap1
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Synonyms: Centg2, Ggap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 347722
Homologene: 56689
Pmepa1
Name: prostate transmembrane protein, androgen induced 1
Synonyms: PMEPA1, STAG1, N4wbp4, Tmepai, 2210418I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 65112
Homologene: 10608
Ddx10
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
Synonyms: 4632415A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 77591
VEGA: 9
HGNC: HGNC:2735
Homologene: 20922
Bnc2
Name: basonuclin 2
Synonyms: 8430420F16Rik, 5031434M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242509
Homologene: 18243
Cabin1
Name: calcineurin binding protein 1
Synonyms: Cain, Ppp3in, A330070M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 104248
VEGA: 10
Homologene: 49307
Sbno1
Name: strawberry notch 1
Synonyms: sno, 9330180L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243272
Homologene: 10055
Trappc12
Name: trafficking protein particle complex 12
Synonyms: CGI-87, D930014A20Rik, Ttc15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217449
VEGA: 12
Homologene: 34805
Eif3e
Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: Eif3s6, eIF3-p48, 48kDa, Int6, eIF3-p46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16341
VEGA: 15
HGNC: HGNC:3277
Homologene: 1205
Akap1
Name: A kinase (PRKA) anchor protein 1
Synonyms: S-AKAP84, DAKAP1, AKAP84, AKAP121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11640
HGNC: HGNC:367
Homologene: 31165
Emsy
Name: EMSY, BRCA2-interacting transcriptional repressor
Synonyms: 2210018M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233545
Homologene: 32465
Git1
Name: GIT ArfGAP 1
Synonyms: p95Cat, Cat-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216963
HGNC: HGNC:4272
Homologene: 32204
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: B130055D15Rik, 4632407J06Rik, 2810487N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 78658
VEGA: 9
Homologene: 41021
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Nif3l1
Name: Ngg1 interacting factor 3-like 1 (S. pombe)
Synonyms: 1110030G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 65102
Homologene: 5881
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Nectin3
Name: nectin cell adhesion molecule 3
Synonyms: Pvrl3, 2610301B19Rik, 4921513D19Rik, 3000002N23Rik, nectin-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 58998
Homologene: 9162
Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Synonyms: 5430432H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19725
VEGA: 17
HGNC: HGNC:9983
Homologene: 30980
Osbpl9
Name: oxysterol binding protein-like 9
Synonyms: ORP-9, 2600011I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100273
Homologene: 69380
Rfwd3
Name: ring finger and WD repeat domain 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234736
Homologene: 41230
Zfp846
Name: zinc finger protein 846
Synonyms: 2210010B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244721
Homologene: 87243
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: A630028O16Rik, LOC380767, 9330197E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 211978
VEGA: 12
Homologene: 9102
Slc25a36
Name: solute carrier family 25, member 36
Synonyms: C330005L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 192287
Homologene: 10039
Rrbp1
Name: ribosome binding protein 1
Synonyms: ES/130, mRRp2, mRRp16.8, mRRp5.4, mRRp15a, 5730465C04Rik, mRRp15b, mRRp47, mRRp10, mRRp41, 1700087N07Rik, mRRp1.8, p180, mRRp0
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 81910
Homologene: 68138
Prkaa1
Name: protein kinase, AMP-activated, alpha 1 catalytic subunit
Synonyms: AMPKalpha1, C130083N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105787
VEGA: 15
HGNC: HGNC:9376
Homologene: 49590
Pprc1
Name: peroxisome proliferative activated receptor, gamma, coactivator-related 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226169
Homologene: 9006
Dennd1a
Name: DENN/MADD domain containing 1A
Synonyms: 6030446I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227801
Homologene: 17141
Wdtc1
Name: WD and tetratricopeptide repeats 1
Synonyms: adipose, adp, LOC230796
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230796
Homologene: 8997
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 623474
Homologene: 8240
Spink4
Name: serine peptidase inhibitor, Kazal type 4
Synonyms: MPGC60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20731
Homologene: 7954
Steap3
Name: STEAP family member 3
Synonyms: pHyde, 1010001D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68428
Homologene: 10084
Gnao1
Name: guanine nucleotide binding protein, alpha O
Synonyms: alphaO, Galphao, Go alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14681
HGNC: HGNC:4389
Homologene: 39203
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Trim9
Name: tripartite motif-containing 9
Synonyms: C030048G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 94090
VEGA: 12
Homologene: 9045
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19266
HGNC: HGNC:9668
Stk10
Name: serine/threonine kinase 10
Synonyms: Lok, Gek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20868
Homologene: 38122
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Ulk4
Name: unc-51-like kinase 4
Synonyms: 4932415A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 209012
Homologene: 41205
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, Heatr7b1, OTTMUSG00000020804
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100040766
Homologene: 85300
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 211223
Homologene: 129606
Gas2l2
Name: growth arrest-specific 2 like 2
Synonyms: OTTMUSG00000000934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237891
Homologene: 16409
Vmn2r111
Name: vomeronasal 2, receptor 111
Synonyms: EG210876
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 210876
Homologene: 86604
Tdrd5
Name: tudor domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 214575
Homologene: 18312
Itgad
Name: integrin, alpha D
Synonyms: Cd11d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381924
HGNC: HGNC:6146
Homologene: 56919
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224833
Homologene: 138294
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: C80743, 2310067L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69700
Homologene: 43567
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 628870
Homologene: 46008
Mus81
Name: MUS81 structure-specific endonuclease subunit
Synonyms: 1200008A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 71711
Homologene: 5725
Osgin1
Name: oxidative stress induced growth inhibitor 1
Synonyms: 1700012B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71839
Homologene: 16325
Sgsm2
Name: small G protein signaling modulator 2
Synonyms: Rutbc1, D630003G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 97761
Homologene: 14780
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 626596
Homologene: 75047
Laptm5
Name: lysosomal-associated protein transmembrane 5
Synonyms: E3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16792
Homologene: 4922
Obsl1
Name: obscurin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98733
Upb1
Name: ureidopropionase, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103149
Homologene: 9471
Tmem117
Name: transmembrane protein 117
Synonyms: B930062P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 320709
VEGA: 15
Homologene: 12992
Cpne4
Name: copine IV
Synonyms: 3632411M23Rik, 4933406O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74020
HGNC: HGNC:2317
Homologene: 26078
Hlx
Name: H2.0-like homeobox
Synonyms: Hlx1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 15284
HGNC: HGNC:4978
Homologene: 7363
Nectin1
Name: nectin cell adhesion molecule 1
Synonyms: HveC, PRR, Pvrl1, HIgR, Cd111, nectin-1, PRR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 58235
VEGA: 9
HGNC: HGNC:9706
Homologene: 2138
C1s2
Name: complement component 1, s subcomponent 2
Synonyms: Gm5077
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 317677
HGNC: HGNC:1247
Homologene: 1314
Rbfox1
Name: RNA binding protein, fox-1 homolog (C. elegans) 1
Synonyms: FOX1, HRNBP1, A2bp, A2bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268859
VEGA: 16
Homologene: 69339
Olfr1198
Name: olfactory receptor 1198
Synonyms: MOR225-13, GA_x6K02T2Q125-50221692-50220766
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 404330
Homologene: 138634
Fpr-rs7
Name: formyl peptide receptor, related sequence 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 321021
C530008M17Rik
Name: RIKEN cDNA C530008M17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320827
Homologene: 136278
Jakmip3
Name: janus kinase and microtubule interacting protein 3
Synonyms: 6330417G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74004
Homologene: 90425
Rps13-ps2
Name: ribosomal protein S13, pseudogene 2
Synonyms: Gm10159
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100039924
Alkbh1
Name: alkB homolog 1, histone H2A dioxygenase
Synonyms: Nrp, alkB, Alkbh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 211064
Homologene: 4393
Mlana
Name: melan-A
Synonyms: Mart1, A930034P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 77836
VEGA: 19
HGNC: HGNC:7124
Homologene: 4026
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,447,943 bp
  • C to A, chromosome 1 at 75,486,784 bp
  • G to C, chromosome 1 at 88,257,802 bp
  • A to G, chromosome 1 at 89,843,186 bp
  • A to T, chromosome 1 at 120,227,820 bp
  • A to G, chromosome 1 at 156,277,487 bp
  • G to T, chromosome 1 at 184,731,987 bp
  • T to C, chromosome 2 at 13,287,568 bp
  • C to A, chromosome 2 at 31,598,551 bp
  • A to C, chromosome 2 at 38,043,400 bp
  • T to G, chromosome 2 at 71,834,034 bp
  • T to C, chromosome 2 at 88,746,834 bp
  • A to G, chromosome 2 at 143,955,112 bp
  • A to G, chromosome 2 at 173,228,081 bp
  • A to G, chromosome 3 at 87,789,611 bp
  • A to G, chromosome 4 at 11,606,152 bp
  • A to G, chromosome 4 at 40,929,121 bp
  • A to G, chromosome 4 at 76,066,200 bp
  • C to T, chromosome 4 at 84,276,068 bp
  • T to C, chromosome 4 at 109,101,156 bp
  • G to T, chromosome 4 at 130,926,209 bp
  • A to G, chromosome 4 at 133,301,807 bp
  • T to C, chromosome 5 at 76,840,910 bp
  • G to T, chromosome 5 at 109,294,087 bp
  • A to T, chromosome 5 at 110,685,478 bp
  • A to G, chromosome 5 at 124,384,460 bp
  • T to A, chromosome 6 at 124,630,167 bp
  • T to C, chromosome 7 at 88,530,547 bp
  • T to C, chromosome 7 at 98,600,841 bp
  • A to T, chromosome 7 at 128,183,006 bp
  • A to T, chromosome 7 at 139,029,646 bp
  • T to A, chromosome 8 at 93,963,437 bp
  • T to C, chromosome 8 at 111,278,288 bp
  • T to A, chromosome 8 at 119,443,113 bp
  • T to A, chromosome 9 at 20,594,097 bp
  • T to A, chromosome 9 at 27,087,566 bp
  • A to G, chromosome 9 at 43,792,099 bp
  • T to A, chromosome 9 at 53,240,487 bp
  • A to C, chromosome 9 at 97,093,073 bp
  • A to T, chromosome 9 at 104,989,632 bp
  • G to C, chromosome 9 at 121,266,258 bp
  • A to T, chromosome 10 at 12,744,049 bp
  • T to C, chromosome 10 at 75,439,942 bp
  • A to G, chromosome 10 at 75,656,806 bp
  • A to G, chromosome 10 at 107,779,252 bp
  • A to G, chromosome 11 at 32,617,919 bp
  • T to C, chromosome 11 at 65,874,132 bp
  • C to A, chromosome 11 at 74,869,138 bp
  • G to T, chromosome 11 at 77,506,418 bp
  • T to C, chromosome 11 at 83,427,472 bp
  • C to A, chromosome 11 at 88,844,751 bp
  • A to G, chromosome 12 at 28,747,161 bp
  • G to A, chromosome 12 at 70,251,093 bp
  • G to T, chromosome 12 at 79,252,163 bp
  • A to G, chromosome 12 at 87,429,145 bp
  • C to T, chromosome 13 at 11,714,503 bp
  • T to C, chromosome 13 at 51,679,723 bp
  • T to C, chromosome 15 at 5,164,744 bp
  • A to G, chromosome 15 at 27,897,914 bp
  • G to T, chromosome 15 at 36,025,793 bp
  • A to G, chromosome 15 at 43,278,428 bp
  • A to G, chromosome 15 at 71,952,377 bp
  • G to A, chromosome 15 at 95,094,597 bp
  • A to G, chromosome 16 at 7,330,433 bp
  • A to T, chromosome 16 at 46,448,394 bp
  • A to G, chromosome 17 at 20,113,607 bp
  • C to A, chromosome 17 at 22,571,116 bp
  • C to A, chromosome 17 at 47,466,662 bp
  • A to T, chromosome 17 at 56,787,720 bp
  • G to C, chromosome 19 at 5,485,117 bp
  • A to T, chromosome 19 at 29,706,852 bp
  • T to A, chromosome 19 at 46,063,736 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1439 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039494-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.