Strain Name:
C57BL/6J-MtgxR1459Btlr/Mmmh
Stock Number:
039514-MU
Citation ID:
RRID:MMRRC_039514-MU
Other Names:
R1459 (G1), C57BL/6J-MtgxR1459Btlr
Major Collection:

Gene Information

Mitf
Name: melanogenesis associated transcription factor
Synonyms: mi, wh, BCC2, bHLHe32, Gsfbcc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17342
HGNC: HGNC:7105
Homologene: 4892
Matr3
Name: matrin 3
Synonyms: D030046F20Rik, 2810017I02Rik, 1110061A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17184
HGNC: HGNC:6912
Homologene: 7830
Mrtfb
Name: myocardin related transcription factor B
Synonyms: MRTF-B, Gt4-1, Mrtfb, Mkl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239719
Homologene: 40917
Cd86
Name: CD86 antigen
Synonyms: B7-2, MB7-2, B70, Ly-58, Cd28l2, B7.2, Ly58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12524
HGNC: HGNC:1705
Homologene: 10443
Prkd3
Name: protein kinase D3
Synonyms: 4930557O20Rik, 5730497N19Rik, PKD3, Prkcn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75292
HGNC: HGNC:9408
Homologene: 2055
Adcyap1
Name: adenylate cyclase activating polypeptide 1
Synonyms: PACAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 11516
VEGA: 17
HGNC: HGNC:241
Homologene: 869
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, Gp330, D230004K18Rik, b2b1625.2Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Gnl3
Name: guanine nucleotide binding protein-like 3 (nucleolar)
Synonyms: nucleostemin, NS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 30877
VEGA: 14
Homologene: 56670
Tnks2
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms: 5430432P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74493
Homologene: 11890
Cdc42bpb
Name: CDC42 binding protein kinase beta
Synonyms: DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217866
VEGA: 12
HGNC: HGNC:1738
Homologene: 55945
Msh2
Name: mutS homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17685
HGNC: HGNC:7325
Homologene: 210
Hnrnpr
Name: heterogeneous nuclear ribonucleoprotein R
Synonyms: hnRNPR, 2610003J05Rik, Hnrpr, 2610528B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74326
HGNC: HGNC:5047
Homologene: 4251
Fbxo42
Name: F-box protein 42
Synonyms: 6720460I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 213499
Homologene: 16234
Apaf1
Name: apoptotic peptidase activating factor 1
Synonyms: Apaf1l, 6230400I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11783
HGNC: HGNC:576
Homologene: 7626
Osbpl11
Name: oxysterol binding protein-like 11
Synonyms: ORP-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106326
Homologene: 23385
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Arfgap3
Name: ADP-ribosylation factor GTPase activating protein 3
Synonyms: 1810004P07Rik, 1810035F16Rik, 0610009H19Rik, 9130416J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66251
VEGA: 15
HGNC: HGNC:661
Homologene: 134103
Ankrd13c
Name: ankyrin repeat domain 13c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433667
Homologene: 41804
Serinc5
Name: serine incorporator 5
Synonyms: AIGP3, A130038L21Rik, TPO1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218442
VEGA: 13
Homologene: 65246
Gabarapl1
Name: gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
Synonyms: GECI, 9130422N19Rik, Apg8l, 3110025G09Rik, Atg8l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 57436
HGNC: HGNC:4068
Homologene: 134420
Sptb
Name: spectrin beta, erythrocytic
Synonyms: Spnb-1, spectrin R, D330027P03Rik, LOC383567, brain erythroid spectrin (235E), Spnb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20741
Homologene: 295
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 6720426B09Rik, 5930437A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77739
Homologene: 64642
Coq7
Name: demethyl-Q 7
Synonyms: clk-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12850
HGNC: HGNC:2244
Homologene: 6953
Top3a
Name: topoisomerase (DNA) III alpha
Synonyms: Top IIIa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21975
Homologene: 3394
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Smurf2
Name: SMAD specific E3 ubiquitin protein ligase 2
Synonyms: 2810411E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66313
Homologene: 41490
Nup160
Name: nucleoporin 160
Synonyms: 2810011M03Rik, Gtl1-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59015
Homologene: 32509
Metap2
Name: methionine aminopeptidase 2
Synonyms: p67, eIF-2-associated p67, A930035J23Rik, 4930584B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56307
Homologene: 4981
Golga2
Name: golgi autoantigen, golgin subfamily a, 2
Synonyms: GM130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99412
HGNC: HGNC:4425
Homologene: 3300
Cep95
Name: centrosomal protein 95
Synonyms: F630025I20Rik, 4732496G21Rik, Ccdc45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320162
Homologene: 16297
Sugp2
Name: SURP and G patch domain containing 2
Synonyms: Sfrs14, Srsf14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234373
Homologene: 8923
Vasn
Name: vasorin
Synonyms: 2610528G05Rik, Slitl2, ATIA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 246154
Homologene: 36929
Ctnnd2
Name: catenin (cadherin associated protein), delta 2
Synonyms: Nprap, Catnd2, neurojugin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18163
VEGA: 15
HGNC: HGNC:2516
Homologene: 55574
Tatdn2
Name: TatD DNase domain containing 2
Synonyms: mKIAA0218
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381801
Homologene: 8848
Abcb4
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Synonyms: mdr-2, Mdr2, Pgy-2, Pgy2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC269160, LOC381317, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Plekhh2
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 213556
VEGA: 17
Homologene: 35317
Mcoln2
Name: mucolipin 2
Synonyms: 3300002C04Rik, mucolipidin 2, TRPML2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68279
Homologene: 12258
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 212167
Homologene: 45504
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102075
Homologene: 18516
Ptpdc1
Name: protein tyrosine phosphatase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218232
VEGA: 13
Homologene: 17576
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Efcab7
Name: EF-hand calcium binding domain 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230500
Homologene: 19952
Gas7
Name: growth arrest specific 7
Synonyms: Gas7-cb, B230343A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14457
HGNC: HGNC:4169
Homologene: 69015
Slc16a7
Name: solute carrier family 16 (monocarboxylic acid transporters), member 7
Synonyms: MCT2, 4921534N07Rik, D630004K10Rik, 9030411M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20503
Homologene: 20990
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52020
VEGA: 17
Homologene: 45466
Lzts2
Name: leucine zipper, putative tumor suppressor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226154
VEGA: 19
Homologene: 15690
Osbpl6
Name: oxysterol binding protein-like 6
Synonyms: ORP-6, 1110062M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99031
Homologene: 101447
Slc22a13b
Name: solute carrier family 22 (organic cation transporter), member 13b
Synonyms: Slc22a13b-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 109280
Vmn2r79
Name: vomeronasal 2, receptor 79
Synonyms: EG621430
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 621430
Homologene: 115466
Nlrp10
Name: NLR family, pyrin domain containing 10
Synonyms: 6430548I20Rik, Pynod, Nalp10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244202
Homologene: 18468
Slc19a1
Name: solute carrier family 19 (folate transporter), member 1
Synonyms: RFC1, RFC-1, reduced folate carrier
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20509
Homologene: 57139
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: PI3Kgamma, p110gamma, PI3Kgamma, PI(3)Kgamma, 5830428L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Grk3
Name: G protein-coupled receptor kinase 3
Synonyms: beta ARK2, Bark-2, Adrbk-2, 4833444A01Rik, Adrbk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320129
HGNC: HGNC:290
Homologene: 21072
Capn5
Name: calpain 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12337
HGNC: HGNC:1482
Homologene: 31212
Pcnp
Name: PEST proteolytic signal containing nuclear protein
Synonyms: 1110018D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 76302
Homologene: 10676
Tcn2
Name: transcobalamin 2
Synonyms: Tcn-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21452
Homologene: 303
Lilrb4a
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4A
Synonyms: CD85K, ILT3, HM18, Gp49b, Lilrb4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14728
VEGA: 10
HGNC: HGNC:6608
Homologene: 86756
Sipa1
Name: signal-induced proliferation associated gene 1
Synonyms: SPA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20469
VEGA: 19
Homologene: 7940
4933430I17Rik
Name: RIKEN cDNA 4933430I17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214106
Homologene: 51897
Cluap1
Name: clusterin associated protein 1
Synonyms: 2310030D15Rik, 2610111M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 76779
Homologene: 14831
Noxa1
Name: NADPH oxidase activator 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241275
Homologene: 18156
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228432
Homologene: 57147
H60c
Name: histocompatibility 60c
Synonyms: Gm9491, 4632413I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 670558
VEGA: 10
Homologene: 120804
Abcb1a
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Synonyms: mdr-3, Mdr1a, P-gp, P-glycoprotein, Pgy-3, Pgy3, multiple drug resistant 1a, MDR3, Pgp, Evi32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18671
HGNC: HGNC:40
Homologene: 55496
Bend4
Name: BEN domain containing 4
Synonyms: EG666938, D330027G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 666938
Homologene: 52626
Fastkd5
Name: FAST kinase domains 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 380601
Homologene: 36400
Cd84
Name: CD84 antigen
Synonyms: CDw84, SLAMF5, A130013D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Dvl1
Name: dishevelled segment polarity protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13542
HGNC: HGNC:3084
Homologene: 20926
Vmn2r69
Name: vomeronasal 2, receptor 69
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330581
Homologene: 115466
Prl7d1
Name: prolactin family 7, subfamily d, member 1
Synonyms: PRP, PLF-RP, Plfr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18814
Homologene: 7894
Adamts14
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
Synonyms: TS14, Adamts-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237360
Homologene: 16383
Ppp2r2b
Name: protein phosphatase 2, regulatory subunit B, beta
Synonyms: 6330404L05Rik, PP2A-PR55B, PR55-BETA, SCA12, 2900026H06Rik, E130009M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 72930
HGNC: HGNC:9305
Homologene: 55833
Bend7
Name: BEN domain containing 7
Synonyms: 1110017O21Rik, E130319B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 209645
Homologene: 17660
Slpi
Name: secretory leukocyte peptidase inhibitor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20568
Homologene: 2305
Phf11
Name: PHD finger protein 11
Synonyms: Phf11-ps, Gm6904
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 628693
VEGA: 14
Cldn19
Name: claudin 19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242653
HGNC: HGNC:2040
Homologene: 17528
Ac225640.2
Name: Uncharacterized protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Cep20
Name: centrosomal protein 20
Synonyms: 0610037P05Rik, Fopnl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66086
Homologene: 11919
Krtap27-1
Name: keratin associated protein 27-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239933
Homologene: 90787
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 171,851,943 bp
  • T to C, chromosome 1 at 188,862,851 bp
  • G to A, chromosome 2 at 4,744,428 bp
  • G to T, chromosome 2 at 25,092,546 bp
  • T to G, chromosome 2 at 32,297,795 bp
  • T to A, chromosome 2 at 69,460,477 bp
  • T to A, chromosome 2 at 69,483,394 bp
  • A to G, chromosome 2 at 76,555,065 bp
  • T to A, chromosome 2 at 90,690,150 bp
  • C to A, chromosome 2 at 110,880,829 bp
  • C to T, chromosome 2 at 130,614,797 bp
  • C to A, chromosome 2 at 164,354,917 bp
  • A to G, chromosome 3 at 146,192,224 bp
  • T to A, chromosome 3 at 157,972,310 bp
  • C to T, chromosome 4 at 62,532,341 bp
  • T to C, chromosome 4 at 86,425,865 bp
  • T to G, chromosome 4 at 99,912,547 bp
  • C to T, chromosome 4 at 119,255,613 bp
  • T to A, chromosome 4 at 136,329,444 bp
  • T to C, chromosome 4 at 141,167,762 bp
  • T to A, chromosome 4 at 155,854,019 bp
  • T to A, chromosome 5 at 8,702,920 bp
  • T to C, chromosome 5 at 8,918,662 bp
  • T to A, chromosome 5 at 21,207,238 bp
  • A to G, chromosome 5 at 67,400,075 bp
  • T to A, chromosome 5 at 112,915,012 bp
  • A to G, chromosome 5 at 124,743,686 bp
  • A to G, chromosome 6 at 98,010,467 bp
  • T to A, chromosome 6 at 113,710,070 bp
  • T to A, chromosome 6 at 129,538,672 bp
  • T to A, chromosome 6 at 149,582,152 bp
  • A to T, chromosome 7 at 85,406,700 bp
  • C to A, chromosome 7 at 87,037,794 bp
  • G to T, chromosome 7 at 98,131,842 bp
  • T to A, chromosome 7 at 108,924,348 bp
  • C to T, chromosome 7 at 118,510,037 bp
  • G to A, chromosome 8 at 48,235,971 bp
  • T to A, chromosome 8 at 70,244,064 bp
  • T to C, chromosome 8 at 105,381,799 bp
  • A to T, chromosome 9 at 119,223,761 bp
  • T to C, chromosome 10 at 3,260,240 bp
  • T to A, chromosome 10 at 51,491,587 bp
  • T to A, chromosome 10 at 61,198,804 bp
  • C to G, chromosome 10 at 77,042,535 bp
  • T to C, chromosome 10 at 91,062,160 bp
  • T to C, chromosome 10 at 93,868,949 bp
  • A to T, chromosome 10 at 125,230,620 bp
  • C to A, chromosome 11 at 3,927,516 bp
  • A to T, chromosome 11 at 60,759,362 bp
  • A to G, chromosome 11 at 67,662,076 bp
  • C to T, chromosome 11 at 106,817,955 bp
  • G to A, chromosome 11 at 106,852,507 bp
  • A to T, chromosome 11 at 115,979,111 bp
  • A to G, chromosome 12 at 8,006,047 bp
  • A to G, chromosome 12 at 8,011,937 bp
  • A to G, chromosome 12 at 32,204,984 bp
  • T to A, chromosome 12 at 76,611,883 bp
  • A to G, chromosome 12 at 111,296,300 bp
  • C to T, chromosome 13 at 27,709,257 bp
  • A to T, chromosome 13 at 48,586,697 bp
  • T to A, chromosome 13 at 92,661,187 bp
  • G to A, chromosome 14 at 31,017,846 bp
  • T to A, chromosome 14 at 59,244,778 bp
  • A to C, chromosome 15 at 30,847,299 bp
  • G to A, chromosome 15 at 83,306,937 bp
  • T to A, chromosome 16 at 3,937,589 bp
  • T to A, chromosome 16 at 4,648,609 bp
  • T to C, chromosome 16 at 13,401,569 bp
  • G to A, chromosome 16 at 14,304,516 bp
  • T to C, chromosome 16 at 33,236,329 bp
  • T to A, chromosome 16 at 36,628,988 bp
  • C to T, chromosome 16 at 56,024,340 bp
  • T to C, chromosome 16 at 88,671,414 bp
  • T to C, chromosome 16 at 91,655,342 bp
  • T to A, chromosome 17 at 30,982,258 bp
  • T to C, chromosome 17 at 30,986,504 bp
  • T to C, chromosome 17 at 78,971,367 bp
  • G to T, chromosome 17 at 84,610,775 bp
  • A to G, chromosome 17 at 87,678,343 bp
  • T to C, chromosome 17 at 93,200,122 bp
  • T to A, chromosome 18 at 35,584,656 bp
  • T to A, chromosome 18 at 42,737,990 bp
  • A to G, chromosome 19 at 5,651,664 bp
  • T to A, chromosome 19 at 36,845,531 bp
  • T to A, chromosome 19 at 45,021,454 bp
  • T to C, chromosome 19 at 56,384,130 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1459 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039514-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.