Strain Name:
C57BL/6J-MtgxR1552Btlr/Mmmh
Stock Number:
039591-MU
Citation ID:
RRID:MMRRC_039591-MU
Other Names:
R1552 (G1), C57BL/6J-MtgxR1552Btlr
Major Collection:

Gene Information

Chrna3
Name: cholinergic receptor, nicotinic, alpha polypeptide 3
Synonyms: (a)3, alpha 3, neuronal nicotinic acetylcholine receptor, alpha 3 subunit, Acra-3, Acra3, A730007P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110834
VEGA: 9
HGNC: HGNC:1957
Homologene: 591
Lamb3
Name: laminin, beta 3
Synonyms: nicein, 125kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16780
HGNC: HGNC:6490
Homologene: 191
Mbd5
Name: methyl-CpG binding domain protein 5
Synonyms: 9430004D19Rik, C030040A15Rik, OTTMUSG00000012483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 109241
Homologene: 81861
Inpp5a
Name: inositol polyphosphate-5-phosphatase A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212111
HGNC: HGNC:6076
Homologene: 4045
Jarid2
Name: jumonji, AT rich interactive domain 2
Synonyms: Jmj, jumonji
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16468
HGNC: HGNC:6196
Homologene: 31279
Upf1
Name: UPF1 regulator of nonsense transcripts homolog (yeast)
Synonyms: PNORF-1, B430202H16Rik, Rent1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19704
HGNC: HGNC:9962
Homologene: 2185
Rnf38
Name: ring finger protein 38
Synonyms: Oip1, 1700065B19Rik, 2610202O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 73469
Homologene: 32550
Chst5
Name: carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
Synonyms: I-GlcNAc6ST, GST-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56773
Homologene: 56927
Zranb3
Name: zinc finger, RAN-binding domain containing 3
Synonyms: 4933425L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226409
Homologene: 32770
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: qkf, querkopf, Morf, B130044K16Rik, monocytic leukemia, Myst4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54169
Homologene: 136480
Exog
Name: endo/exonuclease (5'-3'), endonuclease G-like
Synonyms: ENGL-a, ENDOGL2, ENGL-B, Endogl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208194
VEGA: 9
HGNC: HGNC:3347
Homologene: 3745
Eefsec
Name: eukaryotic elongation factor, selenocysteine-tRNA-specific
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 65967
Homologene: 11073
Wwox
Name: WW domain-containing oxidoreductase
Synonyms: WOX1, 9030416C10Rik, 5330426P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 80707
Homologene: 56334
Dvl2
Name: dishevelled segment polarity protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13543
HGNC: HGNC:3086
Homologene: 20927
Cep170
Name: centrosomal protein 170
Synonyms: 4933426L22Rik, A330004A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545389
Homologene: 22844
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Uhrf1bp1
Name: UHRF1 (ICBP90) binding protein 1
Synonyms: 1110020K19Rik, F830021D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224648
Homologene: 9816
Impact
Name: impact, RWD domain protein
Synonyms: E430016J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16210
VEGA: 18
Homologene: 5490
Fasn
Name: fatty acid synthase
Synonyms: FAS, A630082H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Cep350
Name: centrosomal protein 350
Synonyms: 6430546F08Rik, 4933409L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74081
Homologene: 8879
Mc4r
Name: melanocortin 4 receptor
Synonyms: Fatboy, Pkcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17202
VEGA: 18
HGNC: HGNC:6932
Homologene: 4320
Gas8
Name: growth arrest specific 8
Synonyms: Gas11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104346
HGNC: HGNC:4166
Homologene: 1135
Srsf5
Name: serine and arginine-rich splicing factor 5
Synonyms: Sfrs5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20384
Homologene: 133842
Nek1
Name: NIMA (never in mitosis gene a)-related expressed kinase 1
Synonyms: kat, kidney, anemia and testis, D8Ertd790e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18004
HGNC: HGNC:7744
Homologene: 14376
Abcc5
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 5
Synonyms: Mrp5, Abcc5b, Abcc5a, 2900011L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Synonyms: Byp, DEP-1, Scc-1, Scc1, CD148, RPTPJ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19271
HGNC: HGNC:9673
Homologene: 2130
Smu1
Name: smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
Synonyms: 2600001O03Rik, SMU-1, 2610203K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74255
Homologene: 10079
Arcn1
Name: archain 1
Synonyms: 4632432M07Rik, pale coat neuro, nur17, delta-COP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 213827
HGNC: HGNC:649
Homologene: 1250
Got2
Name: glutamatic-oxaloacetic transaminase 2, mitochondrial
Synonyms: mAspAT, mitochondrial aspartate aminotransferase, FABP-pm, plasma membrane fatty acid binding protein, Kyat4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14719
HGNC: HGNC:4433
Homologene: 1572
Zfp335
Name: zinc finger protein 335
Synonyms: 1810045J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329559
Homologene: 11129
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Gdap2
Name: ganglioside-induced differentiation-associated-protein 2
Synonyms: D3Ertd801e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14547
Homologene: 7728
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Swiss-cheese, MSws, Nte
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50767
Homologene: 21333
Ilkap
Name: integrin-linked kinase-associated serine/threonine phosphatase 2C
Synonyms: 1600009O09Rik, PP2C-DELTA, 0710007A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67444
Homologene: 31525
Stn1
Name: STN1, CST complex subunit
Synonyms: 2310057J23Rik, 0610009H20Rik, Obfc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 108689
Homologene: 11788
Usp54
Name: ubiquitin specific peptidase 54
Synonyms: 4930429G18Rik, C030002J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78787
Homologene: 90902
Phf21b
Name: PHD finger protein 21B
Synonyms: A730032D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 271305
Homologene: 78154
Dclk3
Name: doublecortin-like kinase 3
Synonyms: Click-I, -II related, Dcamkl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245038
Homologene: 70580
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: calcium release channel isoform 1, Ryr, skrr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20190
Homologene: 68069
Exosc9
Name: exosome component 9
Synonyms: PM/Scl-75, RRP45, p6, p5, Pmscl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50911
HGNC: HGNC:9137
Homologene: 3693
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Reln
Name: reelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Unc13b
Name: unc-13 homolog B
Synonyms: Unc13h2, Munc13-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22249
Homologene: 31376
Mipol1
Name: mirror-image polydactyly 1
Synonyms: 1700081O04Rik, 6030439O22Rik, D12Ertd19e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73490
Homologene: 16340
Coro1a
Name: coronin, actin binding protein 1A
Synonyms: p57, coronin 1, Clabp, Lmb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12721
HGNC: HGNC:2252
Homologene: 6545
Kng2
Name: kininogen 2
Synonyms: Kininogen-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 385643
HGNC: HGNC:6383
Homologene: 88343
Stx18
Name: syntaxin 18
Synonyms: 4933425D03Rik, 1810035L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71116
Homologene: 9655
Slfn10-ps
Name: schlafen 10, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237887
Ccdc121
Name: coiled-coil domain containing 121
Synonyms: LOC329308, 6530421E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 403180
Homologene: 136217
Slc30a4
Name: solute carrier family 30 (zinc transporter), member 4
Synonyms: Znt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22785
Homologene: 74984
Rint1
Name: RAD50 interactor 1
Synonyms: 2810450M21Rik, 1500019C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72772
Homologene: 11070
Lingo2
Name: leucine rich repeat and Ig domain containing 2
Synonyms: B230217C06Rik, Lrrn6c, LERN3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242384
Homologene: 17621
Prkch
Name: protein kinase C, eta
Synonyms: Pkch
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18755
HGNC: HGNC:9403
Homologene: 84384
Myo15b
Name: myosin XVB
Synonyms: LOC217328, LOC380737, E330039G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217328
Pcdh8
Name: protocadherin 8
Synonyms: Papc, 1700080P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18530
HGNC: HGNC:8660
Homologene: 1943
Palmd
Name: palmdelphin
Synonyms: 4631423C22Rik, PALML
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 114301
Homologene: 9804
Hadhb
Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
Synonyms: 4930479F15Rik, Mtpb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231086
HGNC: HGNC:4803
Homologene: 153
Smcp
Name: sperm mitochondria-associated cysteine-rich protein
Synonyms: Mcsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17235
HGNC: HGNC:6962
Ugt2a1
Name: UDP glucuronosyltransferase 2 family, polypeptide A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 94215
Homologene: 136808
Kdm4d
Name: lysine (K)-specific demethylase 4D
Synonyms: Jmjd2d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244694
Homologene: 69244
Il1rap
Name: interleukin 1 receptor accessory protein
Synonyms: IL-1R AcP, IL-1RAcP, 6430709H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16180
HGNC: HGNC:5995
Homologene: 1643
Npffr2
Name: neuropeptide FF receptor 2
Synonyms: NPFF2, Gpr74
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 104443
HGNC: HGNC:4525
Homologene: 56982
Klra5
Name: killer cell lectin-like receptor, subfamily A, member 5
Synonyms: Ly49e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16636
Homologene: 110821
Tlr1
Name: toll-like receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21897
Homologene: 20694
Klk1b1
Name: kallikrein 1-related peptidase b1
Synonyms: mGK-1, TK, tissue kallikrein, mK1, Klk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16623
HGNC: HGNC:6364
Homologene: 68141
Calhm1
Name: calcium homeostasis modulator 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 546729
VEGA: 19
Homologene: 55508
Neu1
Name: neuraminidase 1
Synonyms: sialidase 1, lysosomal sialidase, G9, Bat-7, Map-2, Neu-1, Apl, Aglp, Bat7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18010
HGNC: HGNC:7758
Homologene: 375
Radil
Name: Ras association and DIL domains
Synonyms: D930005D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231858
Homologene: 77648
Cyp3a16
Name: cytochrome P450, family 3, subfamily a, polypeptide 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13114
HGNC: HGNC:2638
Homologene: 133568
Cyth3
Name: cytohesin 3
Synonyms: cytohesin 3, Grp1, Pscd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19159
HGNC: HGNC:9504
Homologene: 3116
Ift57
Name: intraflagellar transport 57
Synonyms: MHS4R2, HIPPI, 4833420A15Rik, Esrrbl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 73916
Homologene: 32383
Olfr912
Name: olfactory receptor 912
Synonyms: GA_x6K02T2PVTD-32283590-32284522, MOR165-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258806
VEGA: 9
Homologene: 115510
Cdk5rap1
Name: CDK5 regulatory subunit associated protein 1
Synonyms: 2310066P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66971
Homologene: 9502
Tas2r130
Name: taste receptor, type 2, member 130
Synonyms: Tas2r30, STC 7-4, mt2r42, T2R30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387355
Homologene: 41536
Tescl
Name: tescalcin-like
Synonyms: 1700008P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69301
Homologene: 129777
1810046K07Rik
Name: RIKEN cDNA 1810046K07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69809
Homologene: 18881
Abhd15
Name: abhydrolase domain containing 15
Synonyms: 1300007F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67477
Homologene: 12142
Kcnk18
Name: potassium channel, subfamily K, member 18
Synonyms: LOC332396, Tresk-2, Tresk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 332396
VEGA: 19
Homologene: 133808
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 91,384,594 bp
  • G to A, chromosome 1 at 127,960,751 bp
  • C to T, chromosome 1 at 155,910,738 bp
  • T to C, chromosome 1 at 176,782,494 bp
  • A to G, chromosome 1 at 181,510,991 bp
  • A to G, chromosome 1 at 193,330,759 bp
  • T to C, chromosome 2 at 49,272,934 bp
  • T to C, chromosome 2 at 76,870,700 bp
  • A to T, chromosome 2 at 90,471,153 bp
  • T to A, chromosome 2 at 122,686,016 bp
  • T to C, chromosome 2 at 154,370,695 bp
  • A to G, chromosome 2 at 164,892,472 bp
  • C to T, chromosome 3 at 5,403,110 bp
  • C to T, chromosome 3 at 36,552,755 bp
  • A to T, chromosome 3 at 92,584,403 bp
  • T to A, chromosome 3 at 100,171,050 bp
  • T to A, chromosome 3 at 116,948,040 bp
  • A to G, chromosome 4 at 35,708,315 bp
  • A to C, chromosome 4 at 40,748,570 bp
  • A to T, chromosome 4 at 43,237,144 bp
  • G to C, chromosome 4 at 44,142,468 bp
  • G to T, chromosome 5 at 21,960,378 bp
  • T to A, chromosome 5 at 23,800,658 bp
  • T to A, chromosome 5 at 30,176,933 bp
  • A to G, chromosome 5 at 38,104,991 bp
  • A to G, chromosome 5 at 64,926,860 bp
  • G to T, chromosome 5 at 87,462,021 bp
  • T to C, chromosome 5 at 89,583,116 bp
  • A to G, chromosome 5 at 142,487,189 bp
  • G to A, chromosome 5 at 143,697,750 bp
  • T to C, chromosome 5 at 145,436,536 bp
  • C to T, chromosome 6 at 88,376,200 bp
  • G to T, chromosome 6 at 129,909,885 bp
  • A to G, chromosome 6 at 131,630,167 bp
  • G to T, chromosome 7 at 24,333,333 bp
  • A to G, chromosome 7 at 29,074,714 bp
  • A to G, chromosome 7 at 43,969,343 bp
  • T to C, chromosome 7 at 126,699,952 bp
  • T to C, chromosome 7 at 139,578,344 bp
  • C to A, chromosome 8 at 3,522,403 bp
  • A to C, chromosome 8 at 24,646,361 bp
  • T to A, chromosome 8 at 61,006,737 bp
  • G to A, chromosome 8 at 70,333,059 bp
  • A to G, chromosome 8 at 95,869,494 bp
  • T to C, chromosome 8 at 111,890,280 bp
  • T to A, chromosome 8 at 114,445,350 bp
  • G to A, chromosome 8 at 123,520,646 bp
  • A to T, chromosome 9 at 14,464,029 bp
  • T to C, chromosome 9 at 38,581,379 bp
  • C to T, chromosome 9 at 44,758,994 bp
  • T to A, chromosome 9 at 51,291,570 bp
  • C to A, chromosome 9 at 55,015,908 bp
  • C to A, chromosome 9 at 111,488,579 bp
  • T to C, chromosome 9 at 119,445,110 bp
  • T to A, chromosome 11 at 70,006,372 bp
  • T to C, chromosome 11 at 72,754,495 bp
  • T to C, chromosome 11 at 77,515,407 bp
  • T to C, chromosome 11 at 83,029,850 bp
  • A to C, chromosome 11 at 115,866,635 bp
  • A to G, chromosome 11 at 120,818,558 bp
  • T to C, chromosome 12 at 57,306,088 bp
  • T to C, chromosome 12 at 73,702,546 bp
  • A to G, chromosome 12 at 80,949,745 bp
  • T to C, chromosome 13 at 44,911,199 bp
  • C to T, chromosome 14 at 20,583,309 bp
  • T to G, chromosome 14 at 21,631,308 bp
  • A to T, chromosome 14 at 79,770,607 bp
  • C to T, chromosome 15 at 84,797,413 bp
  • T to A, chromosome 16 at 20,398,867 bp
  • A to T, chromosome 16 at 22,987,520 bp
  • A to G, chromosome 16 at 26,722,434 bp
  • A to G, chromosome 16 at 49,759,353 bp
  • T to C, chromosome 17 at 27,890,071 bp
  • C to T, chromosome 17 at 34,932,113 bp
  • T to C, chromosome 18 at 12,984,280 bp
  • T to C, chromosome 18 at 66,859,695 bp
  • C to T, chromosome 19 at 47,141,201 bp
  • T to C, chromosome 19 at 47,536,373 bp
  • A to T, chromosome 19 at 59,235,458 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1552 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039591-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.