Strain Name:
C57BL/6J-MtgxR1582Btlr/Mmmh
Stock Number:
039619-MU
Citation ID:
RRID:MMRRC_039619-MU
Other Names:
R1582 (G1), C57BL/6J-MtgxR1582Btlr
Major Collection:

Strain Information

Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Nrg4
Name: neuregulin 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83961
Homologene: 12921
Adcy9
Name: adenylate cyclase 9
Synonyms: D16Wsu65e, ACtp10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11515
HGNC: HGNC:240
Homologene: 868
Uri1
Name: URI1, prefoldin-like chaperone
Synonyms: NNX3, C80913, Rmp
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19777
Homologene: 2813
Rbms1
Name: RNA binding motif, single stranded interacting protein 1
Synonyms: YC1, MSSP-2, MSSP-3, 2600014B10Rik, MSSP-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56878
HGNC: HGNC:9907
Homologene: 9640
Kdm5b
Name: lysine demethylase 5B
Synonyms: Rb-Bp2, 2210016I17Rik, Jarid1b, 2010009J12Rik, D1Ertd202e, Plu1, PLU-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75605
Homologene: 48448
Atl3
Name: atlastin GTPase 3
Synonyms: 5730596K20Rik, 4633402C03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 109168
VEGA: 19
Homologene: 9149
Dtnb
Name: dystrobrevin, beta
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13528
HGNC: HGNC:3058
Homologene: 74875
Gria4
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Synonyms: Glur4, spkw1, Gluralpha4, Glur-4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14802
HGNC: HGNC:4574
Homologene: 20227
Ubap2l
Name: ubiquitin-associated protein 2-like
Synonyms: NICE-4, 4932431F02Rik, A430103N23Rik, 3110083O19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74383
Homologene: 136291
Gpbp1
Name: GC-rich promoter binding protein 1
Synonyms: 1700034P14Rik, D230035M11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73274
Homologene: 11292
Naa25
Name: N(alpha)-acetyltransferase 25, NatB auxiliary subunit
Synonyms: 4833422K13Rik, C330023M02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231713
Homologene: 6891
Septin11
Name: septin 11
Synonyms: D5Ertd606e, 6230410I01Rik, Sept11
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52398
Homologene: 56800
Sec24a
Name: SEC24 homolog A, COPII coat complex component
Synonyms: 9430090N21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77371
Homologene: 70131
Rsf1
Name: remodeling and spacing factor 1
Synonyms: Hbxap, p325, XAP8, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Mark3
Name: MAP/microtubule affinity regulating kinase 3
Synonyms: A430080F22Rik, ETK-1, 1600015G02Rik, C-TAK1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 17169
VEGA: 12
HGNC: HGNC:6897
Homologene: 55653
Abl1
Name: c-abl oncogene 1, non-receptor tyrosine kinase
Synonyms: E430008G22Rik, c-Abl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11350
HGNC: HGNC:76
Homologene: 3783
Fabp3
Name: fatty acid binding protein 3, muscle and heart
Synonyms: Fabph-1, Mdgi, Fabph1, H-FABP, Fabph-4, Fabp3, Fabph4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14077
HGNC: HGNC:3557
Homologene: 68379
Cir1
Name: corepressor interacting with RBPJ, 1
Synonyms: CIR, 1700023B02Rik, 2810021A19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66935
Homologene: 3589
Wdr25
Name: WD repeat domain 25
Synonyms: B930090D16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 212198
VEGA: 12
Homologene: 56993
Muc15
Name: mucin 15
Synonyms: D730046L02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269328
Homologene: 51680
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Fam135a
Name: family with sequence similarity 135, member A
Synonyms: 4921533L14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68187
Homologene: 32665
Actr3
Name: ARP3 actin-related protein 3
Synonyms: Arp3, 1200003A09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74117
HGNC: HGNC:170
Homologene: 68483
Nup160
Name: nucleoporin 160
Synonyms: 2810011M03Rik, Gtl1-13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 59015
Homologene: 32509
Bicra
Name: BRD4 interacting chromatin remodeling complex associated protein
Synonyms: Gltscr1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243842
HGNC: HGNC:4332
Homologene: 9250
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229473
Homologene: 9057
Lct
Name: lactase
Synonyms: LOC226413, LPH, Lphl
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226413
HGNC: HGNC:6530
Homologene: 124204
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 328783
VEGA: 17
Homologene: 18633
Ppara
Name: peroxisome proliferator activated receptor alpha
Synonyms: 4933429D07Rik, PPAR-alpha, PPARalpha, Nr1c1, Ppar
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19013
HGNC: HGNC:9232
Homologene: 21047
Kctd19
Name: potassium channel tetramerisation domain containing 19
Synonyms: 4922504H04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 279499
Homologene: 18630
Fbn2
Name: fibrillin 2
Synonyms: Fib-2, sy, Sne
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Relt
Name: RELT tumor necrosis factor receptor
Synonyms: E430021K24Rik, Tnfrsf19l
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320100
Homologene: 13151
Ddhd1
Name: DDHD domain containing 1
Synonyms: 9630061G18Rik, 4921528E07Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 114874
Homologene: 35221
Spata6
Name: spermatogenesis associated 6
Synonyms: KRP, Hash, 1700062C23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67946
Homologene: 10410
4932441B19Rik
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 9430041O17Rik, 2010203O03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234214
Homologene: 83295
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Adamts19
Name: ADAM metallopeptidase with thrombospondin type 1 motif 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240322
VEGA: 18
Homologene: 15860
Thbs2
Name: thrombospondin 2
Synonyms: Thrombospondin-2, Thbs-2, TSP2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Or1e1c
Name: olfactory receptor family 1 subfamily E member 1C
Synonyms: MOR135-12, GA_x6K02T2P1NL-3535075-3536028, Olfr376
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258924
Homologene: 133579
Smarca2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms: 2610209L14Rik, Snf2l2, brm
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67155
Homologene: 2308
Unc45b
Name: unc-45 myosin chaperone B
Synonyms: Cmya4, D230041A13Rik, UNC45
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217012
Homologene: 14666
Or5e1
Name: olfactory receptor family 5 subfamily E member 1
Synonyms: MOR195-1, GA_x6K02T2PBJ9-11084889-11085818, Olfr513
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258718
Homologene: 64908
Hdac10
Name: histone deacetylase 10
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170787
Homologene: 23749
Ehbp1l1
Name: EH domain binding protein 1-like 1
Synonyms: G430002G23Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 114601
VEGA: 19
Homologene: 136059
Abcc1
Name: ATP-binding cassette, sub-family C member 1
Synonyms: Mrp1, Abcc1a, Mdrap, MRP, Abcc1b
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17250
HGNC: HGNC:51
Homologene: 133779
Mpped1
Name: metallophosphoesterase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223726
HGNC: HGNC:1306
Homologene: 15012
Vmn1r117
Name: vomeronasal 1 receptor 117
Synonyms: Gm8544
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 667262
Homologene: 104166
Usp21
Name: ubiquitin specific peptidase 21
Synonyms: W53272, ESTM28, Usp16, Usp23
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 30941
Homologene: 56572
Vmn1r7
Name: vomeronasal 1 receptor 7
Synonyms: V1rc31, Gm5568
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 434016
Homologene: 83427
Ddx25
Name: DEAD box helicase 25
Synonyms: GRTH, DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 30959
Homologene: 8310
Tpbpa
Name: trophoblast specific protein alpha
Synonyms: clone 4311, Tb-1, Tb1, Tpbp, 4311
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21984
VEGA: 13
Homologene: 49203
Mosmo
Name: modulator of smoothened
Synonyms: BC030336
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233812
Homologene: 16600
Or6z3
Name: olfactory receptor family 6 subfamily Z member 3
Synonyms: GA_x6K02T2QGBW-3190370-3191314, MOR103-7, Olfr1336
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258917
Homologene: 37007
Dcun1d2
Name: defective in cullin neddylation 1 domain containing 2
Synonyms: DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102323
Homologene: 85990
Tas2r108
Name: taste receptor, type 2, member 108
Synonyms: T2r8, T2R8, T2R108, mGR08, mt2r8
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 57253
Homologene: 49480
Bpifa2
Name: BPI fold containing family A, member 2
Synonyms: Psp, Bpifa2e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19194
Homologene: 69034
BC007180
Name: cDNA sequence BC007180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Rps6kl1
Name: ribosomal protein S6 kinase-like 1
Synonyms: A830084F09Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238323
VEGA: 12
Homologene: 12874
Prss27
Name: serine protease 27
Synonyms: Mpn, Pancreasin, CAPH2, marapsin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213171
Homologene: 23743
H2-Oa
Name: histocompatibility 2, O region alpha locus
Synonyms: H-2Oa
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15001
HGNC: HGNC:4936
Homologene: 1601
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 24,029,317 bp
  • A to G, chromosome 1 at 125,405,925 bp
  • T to C, chromosome 1 at 128,300,562 bp
  • T to A, chromosome 1 at 134,624,853 bp
  • A to T, chromosome 1 at 171,283,081 bp
  • C to G, chromosome 2 at 31,800,359 bp
  • A to T, chromosome 2 at 60,758,835 bp
  • A to T, chromosome 2 at 73,306,840 bp
  • T to C, chromosome 2 at 90,722,016 bp
  • A to T, chromosome 2 at 110,737,472 bp
  • T to C, chromosome 2 at 154,013,718 bp
  • T to C, chromosome 3 at 83,931,783 bp
  • A to G, chromosome 3 at 90,034,671 bp
  • T to C, chromosome 3 at 154,764,323 bp
  • C to G, chromosome 4 at 111,780,795 bp
  • C to T, chromosome 4 at 111,780,797 bp
  • C to T, chromosome 4 at 130,312,387 bp
  • T to C, chromosome 5 at 93,162,121 bp
  • T to A, chromosome 5 at 121,434,829 bp
  • T to A, chromosome 6 at 40,493,632 bp
  • T to C, chromosome 6 at 57,025,158 bp
  • A to G, chromosome 6 at 84,097,767 bp
  • A to G, chromosome 7 at 6,460,814 bp
  • T to C, chromosome 7 at 15,978,678 bp
  • A to T, chromosome 7 at 20,883,559 bp
  • A to G, chromosome 7 at 37,965,386 bp
  • CG to CGACGGCGGGG, chromosome 7 at 97,579,908 bp
  • C to T, chromosome 7 at 100,851,353 bp
  • G to T, chromosome 7 at 108,755,110 bp
  • A to G, chromosome 7 at 120,730,505 bp
  • A to G, chromosome 8 at 13,280,926 bp
  • G to A, chromosome 8 at 45,805,777 bp
  • G to A, chromosome 8 at 105,395,460 bp
  • A to G, chromosome 9 at 4,537,822 bp
  • T to C, chromosome 9 at 35,545,976 bp
  • G to T, chromosome 9 at 55,249,172 bp
  • T to C, chromosome 9 at 108,105,092 bp
  • A to G, chromosome 11 at 51,708,967 bp
  • T to A, chromosome 11 at 73,375,264 bp
  • G to A, chromosome 11 at 82,925,945 bp
  • C to T, chromosome 12 at 3,773,554 bp
  • T to A, chromosome 12 at 85,138,745 bp
  • T to C, chromosome 12 at 108,898,054 bp
  • G to A, chromosome 12 at 111,655,310 bp
  • A to G, chromosome 13 at 46,793,922 bp
  • T to A, chromosome 13 at 60,940,059 bp
  • C to A, chromosome 13 at 65,033,224 bp
  • T to C, chromosome 13 at 111,436,532 bp
  • A to T, chromosome 14 at 45,605,109 bp
  • C to T, chromosome 15 at 83,791,990 bp
  • T to C, chromosome 15 at 85,798,228 bp
  • A to T, chromosome 15 at 89,127,908 bp
  • T to A, chromosome 16 at 4,323,964 bp
  • A to T, chromosome 16 at 14,466,098 bp
  • G to T, chromosome 17 at 14,671,288 bp
  • A to G, chromosome 17 at 24,044,903 bp
  • G to A, chromosome 17 at 25,742,934 bp
  • A to T, chromosome 17 at 34,094,721 bp
  • C to T, chromosome 18 at 58,037,090 bp
  • A to G, chromosome 18 at 58,969,941 bp
  • A to G, chromosome 19 at 5,721,967 bp
  • A to G, chromosome 19 at 7,516,899 bp
  • G to A, chromosome 19 at 26,751,905 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1582 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039619-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.