Strain Name:
C57BL/6J-MtgxR1603Btlr/Mmmh
Stock Number:
039640-MU
Citation ID:
RRID:MMRRC_039640-MU
Other Names:
R1603 (G1), C57BL/6J-MtgxR1603Btlr
Major Collection:

Gene Information

Sema7a
Name: sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
Synonyms: Semaphorin K1, CDw108, Semal, 2900057C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20361
VEGA: 9
Homologene: 2678
Sgpl1
Name: sphingosine phosphate lyase 1
Synonyms: D10Xrf456
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20397
Homologene: 2897
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, D16Jhu32e, 1110051N18Rik, Zcwcc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 338467
Homologene: 32257
Zfp939
Name: zinc finger protein 939
Synonyms: 9430025M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233147
Homologene: 136498
Aebp2
Name: AE binding protein 2
Synonyms: B230313N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11569
Homologene: 40690
Asap1
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain1
Synonyms: Ddef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13196
HGNC: HGNC:2720
Homologene: 7684
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Tip5, Walp3, C030005G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: trithorax Drosophila, HTRX1, ALL-1, All1, Cxxc7, Mll, Mll1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Rpap3
Name: RNA polymerase II associated protein 3
Synonyms: 2310042P20Rik, D15Ertd682e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71919
VEGA: 15
Homologene: 11613
Unc13d
Name: unc-13 homolog D
Synonyms: Munc13-4, 2610108D09Rik, Jinx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70450
Homologene: 26714
Kras
Name: Kirsten rat sarcoma viral oncogene homolog
Synonyms: Ki-ras, Kras-2, K-ras, Kras2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16653
HGNC: HGNC:6407
Homologene: 37990
Tent2
Name: terminal nucleotidyltransferase 2
Synonyms: 8030446C20Rik, Papd4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100715
VEGA: 13
Homologene: 44022
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 6720426B09Rik, 5930437A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77739
Homologene: 64642
Rbl1
Name: RB transcriptional corepressor like 1
Synonyms: p107, retinoblastoma-like 1 (p107)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19650
HGNC: HGNC:9893
Homologene: 2172
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218333
VEGA: 13
Homologene: 18902
Usf3
Name: upstream transcription factor family member 3
Synonyms: LOC207806, LOC385650, 5530400K22Rik, Gm608
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207806
Homologene: 19504
Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: Idh-2, IDPm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269951
HGNC: HGNC:5383
Homologene: 37590
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1134Clo, b2b1537Clo, b2b1565Clo, b2b1154Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Mcoln2
Name: mucolipin 2
Synonyms: 3300002C04Rik, mucolipidin 2, TRPML2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68279
Homologene: 12258
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: Dagk3, E430001K23Rik, 2900055E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Chga
Name: chromogranin A
Synonyms: ChrA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 12652
VEGA: 12
HGNC: HGNC:1929
Homologene: 976
4931408C20Rik
Name: RIKEN cDNA 4931408C20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210940
Homologene: 86827
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Mtr1, Ltrpc5, 9430099A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56843
Homologene: 22818
Zscan20
Name: zinc finger and SCAN domains 20
Synonyms: Zfp31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269585
Homologene: 51463
Poteg
Name: POTE ankyrin domain family, member G
Synonyms: 4930456F22Rik, 4921537P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70952
Homologene: 134158
Trim30b
Name: tripartite motif-containing 30B
Synonyms: Trim30-1, A530023O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244183
Adrb2
Name: adrenergic receptor, beta 2
Synonyms: beta 2-AR, Badm, Adrb-2, beta 2-adrenoceptor, Gpcr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11555
VEGA: 18
HGNC: HGNC:286
Homologene: 30948
Pcnx2
Name: pecanex homolog 2
Synonyms: E330039K12Rik, Pcnxl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270109
HGNC: HGNC:8736
Homologene: 8987
Matn2
Name: matrilin 2
Synonyms: Crtm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17181
VEGA: 15
HGNC: HGNC:6908
Homologene: 20538
Lrrc66
Name: leucine rich repeat containing 66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231296
Homologene: 51944
Mak
Name: male germ cell-associated kinase
Synonyms: A930010O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17152
VEGA: 13
HGNC: HGNC:6816
Homologene: 31344
Ankrd42
Name: ankyrin repeat domain 42
Synonyms: 4933417L02Rik, Ikbn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73845
Homologene: 23652
Vmn2r91
Name: vomeronasal 2, receptor 91
Synonyms: EG665210
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 665210
Homologene: 115024
Osbpl3
Name: oxysterol binding protein-like 3
Synonyms: OSBP3, ORP3, 1200014M06Rik, 6720421I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71720
Homologene: 49422
Grk5
Name: G protein-coupled receptor kinase 5
Synonyms: Gprk5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14773
VEGA: 19
HGNC: HGNC:4544
Homologene: 3879
AC168120.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Atp8b3
Name: ATPase, class I, type 8B, member 3
Synonyms: SAPLT, 1700042F02Rik, 1700056N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67331
VEGA: 10
Homologene: 19034
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 636808
Homologene: 43974
Olfr1437
Name: olfactory receptor 1437
Synonyms: GA_x6K02T2RE5P-2658227-2657289, MOR214-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258117
Homologene: 83129
Parp8
Name: poly (ADP-ribose) polymerase family, member 8
Synonyms: 2810430O08Rik, D13Ertd275e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 52552
VEGA: 13
Homologene: 11621
Dlgap3
Name: DLG associated protein 3
Synonyms: PSD-95/SAP90-binding protein 3, SAP90/PSD 95 associated protein 3, DAP3, Sapap3, Prpl8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242667
Homologene: 18276
Abcc10
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Synonyms: Mrp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224814
HGNC: HGNC:52
Homologene: 58616
Gba2
Name: glucosidase beta 2
Synonyms: bile acid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230101
Homologene: 10859
Fbxw22
Name: F-box and WD-40 domain protein 22
Synonyms: Gm5164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382156
Homologene: 110776
Pom121l2
Name: POM121 membrane glycoprotein-like 2 (rat)
Synonyms: LOC195236
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 195236
Homologene: 123536
Ace
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms: CD143
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11421
HGNC: HGNC:2707
Homologene: 37351
1110032F04Rik
Name: RIKEN cDNA 1110032F04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68725
Homologene: 110165
Olfr319
Name: olfactory receptor 319
Synonyms: GA_x6K02T2NKPP-708319-707399, MOR285-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258493
Lactb
Name: lactamase, beta
Synonyms: Mrpl56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80907
VEGA: 9
Homologene: 12755
Olfr733
Name: olfactory receptor 733
Synonyms: GA_x6K02T2PMLR-5992342-5991416, MOR241-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258657
Homologene: 128266
Fgl1
Name: fibrinogen-like protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234199
HGNC: HGNC:3695
Homologene: 37927
Slc22a28
Name: solute carrier family 22, member 28
Synonyms: Gm5631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 434674
VEGA: 19
Homologene: 77136
Psmc3
Name: proteasome (prosome, macropain) 26S subunit, ATPase 3
Synonyms: Tat binding protein 1, TBP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19182
HGNC: HGNC:9549
Homologene: 2097
Ctdsp1
Name: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
Synonyms: SCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227292
Homologene: 100834
Gimap7
Name: GTPase, IMAP family member 7
Synonyms: IAN7, Ian3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 231932
Homologene: 134307
Obp2a
Name: odorant binding protein 2A
Synonyms: Lcn13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227627
Homologene: 136130
AC119271.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
AC079644.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Ttc33
Name: tetratricopeptide repeat domain 33
Synonyms: 2410099M07Rik, 2900001O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67515
Homologene: 8226
Unc93a
Name: unc-93 homolog A
Synonyms: Unc93l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381058
Homologene: 10356
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 26,685,569 bp
  • T to C, chromosome 1 at 74,393,267 bp
  • A to C, chromosome 1 at 116,412,101 bp
  • G to A, chromosome 2 at 25,702,745 bp
  • A to G, chromosome 2 at 91,054,346 bp
  • G to A, chromosome 2 at 157,175,659 bp
  • G to A, chromosome 3 at 68,870,213 bp
  • G to A, chromosome 3 at 75,396,870 bp
  • A to G, chromosome 3 at 144,922,019 bp
  • C to T, chromosome 3 at 146,180,222 bp
  • C to T, chromosome 4 at 43,567,823 bp
  • A to G, chromosome 4 at 86,415,530 bp
  • G to A, chromosome 4 at 127,195,228 bp
  • A to T, chromosome 4 at 128,591,804 bp
  • G to A, chromosome 5 at 73,607,426 bp
  • A to T, chromosome 6 at 48,723,930 bp
  • C to A, chromosome 6 at 50,323,093 bp
  • A to G, chromosome 6 at 140,642,253 bp
  • A to T, chromosome 6 at 145,225,145 bp
  • T to A, chromosome 7 at 39,473,271 bp
  • T to C, chromosome 7 at 68,618,872 bp
  • T to G, chromosome 7 at 80,099,158 bp
  • T to C, chromosome 7 at 92,619,691 bp
  • T to G, chromosome 7 at 104,365,812 bp
  • G to T, chromosome 7 at 105,762,770 bp
  • A to G, chromosome 7 at 143,085,209 bp
  • T to A, chromosome 8 at 27,448,005 bp
  • T to A, chromosome 8 at 41,197,018 bp
  • G to A, chromosome 8 at 125,839,626 bp
  • A to T, chromosome 9 at 44,841,561 bp
  • G to A, chromosome 9 at 57,960,676 bp
  • A to T, chromosome 9 at 66,971,378 bp
  • T to C, chromosome 9 at 79,612,962 bp
  • G to T, chromosome 9 at 109,378,847 bp
  • C to T, chromosome 10 at 61,105,451 bp
  • C to A, chromosome 10 at 80,525,785 bp
  • C to A, chromosome 10 at 128,121,678 bp
  • T to C, chromosome 11 at 58,702,460 bp
  • T to A, chromosome 11 at 105,972,099 bp
  • T to C, chromosome 11 at 116,073,655 bp
  • C to A, chromosome 12 at 88,018,364 bp
  • T to A, chromosome 12 at 102,564,607 bp
  • A to T, chromosome 13 at 21,983,344 bp
  • T to C, chromosome 13 at 41,042,106 bp
  • A to G, chromosome 13 at 70,603,353 bp
  • G to A, chromosome 13 at 93,175,565 bp
  • A to T, chromosome 13 at 116,869,414 bp
  • T to G, chromosome 14 at 50,299,034 bp
  • A to G, chromosome 15 at 5,189,794 bp
  • A to G, chromosome 15 at 28,294,985 bp
  • A to T, chromosome 15 at 28,449,180 bp
  • T to C, chromosome 15 at 34,388,768 bp
  • A to T, chromosome 15 at 64,129,257 bp
  • T to C, chromosome 15 at 97,701,121 bp
  • T to A, chromosome 16 at 22,570,159 bp
  • T to A, chromosome 16 at 44,218,172 bp
  • C to A, chromosome 16 at 93,866,503 bp
  • T to A, chromosome 17 at 13,109,634 bp
  • T to C, chromosome 17 at 18,106,143 bp
  • T to C, chromosome 17 at 46,312,921 bp
  • A to T, chromosome 18 at 62,179,508 bp
  • A to G, chromosome 19 at 8,063,309 bp
  • A to T, chromosome 19 at 12,321,984 bp
  • T to C, chromosome 19 at 61,069,362 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1603 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039640-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.