Strain Name:
C57BL/6J-MtgxR1617Btlr/Mmmh
Stock Number:
039654-MU
Citation ID:
RRID:MMRRC_039654-MU
Other Names:
R1617 (G1), C57BL/6J-MtgxR1617Btlr
Major Collection:

Gene Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231051
Homologene: 46480
Ppm1a
Name: protein phosphatase 1A, magnesium dependent, alpha isoform
Synonyms: Mpp alpha, MMPa-2, MPPa-1, 2900017D14Rik, 2310003C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19042
VEGA: 12
HGNC: HGNC:9275
Homologene: 56428
Upp1
Name: uridine phosphorylase 1
Synonyms: UdRPase, UPase, Up
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22271
Homologene: 2524
Birc2
Name: baculoviral IAP repeat-containing 2
Synonyms: mcIAP1, MIAP1, IAP1, MIHB, Api1, cIAP1, cIAP-1, HIAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11797
HGNC: HGNC:590
Homologene: 900
Nphs1
Name: nephrosis 1, nephrin
Synonyms: nephrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54631
HGNC: HGNC:7908
Homologene: 20974
Tbcel
Name: tubulin folding cofactor E-like
Synonyms: E130107N23Rik, Lrrc35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 272589
Homologene: 16120
Spred1
Name: sprouty protein with EVH-1 domain 1, related sequence
Synonyms: Spred-1, 5730461F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 114715
Homologene: 24919
Ung
Name: uracil DNA glycosylase
Synonyms: UNG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22256
Homologene: 6585
Srek1
Name: splicing regulatory glutamine/lysine-rich protein 1
Synonyms: SRrp508, SRrp86, Sfrs12, AL118220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218543
Homologene: 10581
Prr12
Name: proline rich 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233210
Homologene: 18957
Psat1
Name: phosphoserine aminotransferase 1
Synonyms: PSA, D8Ertd814e, EPIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107272
Homologene: 6973
Lmtk2
Name: lemur tyrosine kinase 2
Synonyms: 2900041G10Rik, KPI-2, cprk, KPI2, A330101P12Rik, BREK, AATYK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231876
Homologene: 8948
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 5730405K23Rik, 4921511H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207932
Homologene: 45941
Ric8b
Name: RIC8 guanine nucleotide exchange factor B
Synonyms: Ric-8, Ric-8b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237422
VEGA: 10
Homologene: 23080
4833420G17Rik
Name: RIKEN cDNA 4833420G17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67392
VEGA: 13
Homologene: 18889
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67534
Homologene: 8764
Fam160a2
Name: family with sequence similarity 160, member A2
Synonyms: 4632419K20Rik, 6530415H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74349
Homologene: 75329
Glmp
Name: glycosylated lysosomal membrane protein
Synonyms: NCU-G1, 0610031J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56700
Homologene: 10562
Hnrnpa2b1
Name: heterogeneous nuclear ribonucleoprotein A2/B1
Synonyms: Hnrpa2, 9130414A06Rik, Hnrpa2b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53379
HGNC: HGNC:5033
Homologene: 22992
Socs2
Name: suppressor of cytokine signaling 2
Synonyms: SOCS-2, cytokine-inducible SH2 protein 2, STAT-induced STAT inhibitor 2, SSI-2, CIS2, JAB, Cish2, D130043N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216233
Homologene: 2880
Adgre5
Name: adhesion G protein-coupled receptor E5
Synonyms: EGF-TM7 receptor, Cd97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 26364
HGNC: HGNC:1711
Homologene: 8050
Nup160
Name: nucleoporin 160
Synonyms: 2810011M03Rik, Gtl1-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59015
Homologene: 32509
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: E430013P11Rik, NRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241274
Homologene: 62431
Map1s
Name: microtubule-associated protein 1S
Synonyms: VCY2IP1, 6430517J16Rik, Bpy2ip1, Map8, Mtap1s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270058
Homologene: 10047
Zfc3h1
Name: zinc finger, C3H1-type containing
Synonyms: Psrc2, Ccdc131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216345
Homologene: 17017
Slc44a3
Name: solute carrier family 44, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213603
Homologene: 64830
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: Trrp7, LTRPC2, TRPC7, 9830168K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 28240
Homologene: 20709
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Blnk
Name: B cell linker
Synonyms: SLP-65, BCA, BASH, BLNK, Ly-57, Bca, Ly57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17060
Homologene: 32038
Zfp268
Name: zinc finger protein 268
Synonyms: Gm13212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433801
Homologene: 133076
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 665700
Homologene: 90772
Syn2
Name: synapsin II
Synonyms: 2900074L19Rik, Synapsin IIb, Synapsin IIa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20965
Homologene: 49348
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212728
Homologene: 38082
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
AAdacl4fm3
Name: AADACL4 family member 3
Synonyms: Gm13178
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 546849
Homologene: 82586
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Snx13
Name: sorting nexin 13
Synonyms: RGS-PX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217463
VEGA: 12
Homologene: 41011
Tapbp
Name: TAP binding protein
Synonyms: tapasin, TPN, D17Wsu91e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21356
Homologene: 2401
Cpsf1
Name: cleavage and polyadenylation specific factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 94230
VEGA: 15
HGNC: HGNC:2324
Homologene: 40865
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Galnt11
Name: polypeptide N-acetylgalactosaminyltransferase 11
Synonyms: E430002F06Rik, A430075I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231050
Homologene: 11126
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Plcb1
Name: phospholipase C, beta 1
Synonyms: 3110043I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18795
Homologene: 22876
Pcdhb5
Name: protocadherin beta 5
Synonyms: Pcdhb4A, PcdhbE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Adamts16
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 271127
Homologene: 15146
Ttc21b
Name: tetratricopeptide repeat domain 21B
Synonyms: 2410066K11Rik, line 158, Thm1, aln
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73668
Homologene: 57006
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
Grik3
Name: glutamate receptor, ionotropic, kainate 3
Synonyms: Glur-7, Glur7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14807
HGNC: HGNC:4581
Homologene: 73901
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 53419
Homologene: 4804
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329421
Homologene: 51393
Fbrs
Name: fibrosin
Synonyms: Fbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14123
Homologene: 79554
Osgepl1
Name: O-sialoglycoprotein endopeptidase-like 1
Synonyms: MGC13061, 2610001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72085
Homologene: 5561
Smarcd3
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
Synonyms: 1500001J14Rik, BAF60C, 2210409C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66993
Homologene: 2314
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Akr1c21
Name: aldo-keto reductase family 1, member C21
Synonyms: 9430025F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 77337
Homologene: 134114
Lmln
Name: leishmanolysin-like (metallopeptidase M8 family)
Synonyms: 5330415H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239833
Homologene: 13198
Tec
Name: tec protein tyrosine kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21682
Homologene: 1302
Ppp1r32
Name: protein phosphatase 1, regulatory subunit 32
Synonyms: IIIG9L, IIIG9, IIIG9S, 4930579J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67752
VEGA: 19
Homologene: 15863
Pla2g6
Name: phospholipase A2, group VI
Synonyms: iPLA2, iPLA2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 53357
HGNC: HGNC:9039
Homologene: 2635
Olfr1061
Name: olfactory receptor 1061
Synonyms: GA_x6K02T2Q125-47883395-47882454, MOR188-1, MOR188-9, MOR188-1, MOR188-7, Olfr1515
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259022
Homologene: 79468
Tmprss11g
Name: transmembrane protease, serine 11g
Synonyms: 9930032O22Rik, Desc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320454
Homologene: 82239
Gm9894
Name: predicted gene 9894
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100417934
VEGA: 13
Vmn1r197
Name: vomeronasal 1 receptor 197
Synonyms: V1rh21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171278
Homologene: 110880
Arid3c
Name: AT rich interactive domain 3C (BRIGHT-like)
Synonyms: OTTMUSG00000006683
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 550619
Homologene: 72499
Olfr48
Name: olfactory receptor 48
Synonyms: IC3, MOR232-5, GA_x6K02T2Q125-51285881-51284976
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18347
Homologene: 85936
Vav3
Name: vav 3 oncogene
Synonyms: A530094I06Rik, Idd18.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 57257
Homologene: 38143
Ptpn9
Name: protein tyrosine phosphatase, non-receptor type 9
Synonyms: Meg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56294
VEGA: 9
HGNC: HGNC:9661
Homologene: 2121
Mgat4d
Name: MGAT4 family, member C
Synonyms: 4933434I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67555
Homologene: 128538
Amz2
Name: archaelysin family metallopeptidase 2
Synonyms: ESTM12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100503496
Utp11
Name: UTP11 small subunit processome component
Synonyms: 2700082D03Rik, Utp11l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67205
Homologene: 6349
Rps4l
Name: ribosomal protein S4-like
Synonyms: 1110033J19Rik, Rps4y2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66184
Zfp493
Name: zinc finger protein 493
Synonyms: 2900054J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72958
Cyp2d34
Name: cytochrome P450, family 2, subfamily d, polypeptide 34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223706
VEGA: 15
Homologene: 86099
Vmn2r-ps158
Name: vomeronasal 2, receptor, pseudogene 158
Synonyms: Gm9268, Vmn2r126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 668612
Homologene: 104832
Ubqln3
Name: ubiquilin 3
Synonyms: 4933400K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244178
Homologene: 9700
Aqp7
Name: aquaporin 7
Synonyms: AQP7L, AQPap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11832
HGNC: HGNC:640
Homologene: 48000
Zfp92
Name: zinc finger protein 92
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 22754
Homologene: 69050
Dhrs7c
Name: dehydrogenase/reductase (SDR family) member 7C
Synonyms: 1110001P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68460
Homologene: 19108
Zfp46
Name: zinc finger protein 46
Synonyms: Zfp-46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22704
Homologene: 40684
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 14,873,675 bp
  • T to A, chromosome 1 at 20,198,050 bp
  • G to A, chromosome 1 at 53,321,582 bp
  • G to A, chromosome 1 at 74,679,401 bp
  • T to C, chromosome 1 at 150,745,027 bp
  • T to A, chromosome 2 at 25,016,498 bp
  • T to C, chromosome 2 at 27,952,381 bp
  • C to T, chromosome 2 at 31,384,980 bp
  • G to T, chromosome 2 at 66,226,035 bp
  • G to T, chromosome 2 at 70,281,218 bp
  • A to T, chromosome 2 at 86,413,691 bp
  • T to C, chromosome 2 at 89,844,254 bp
  • T to A, chromosome 2 at 90,679,499 bp
  • C to T, chromosome 2 at 117,175,347 bp
  • A to T, chromosome 2 at 135,337,441 bp
  • A to G, chromosome 3 at 88,328,119 bp
  • A to T, chromosome 3 at 109,510,978 bp
  • G to A, chromosome 3 at 121,461,265 bp
  • A to C, chromosome 4 at 41,036,109 bp
  • G to A, chromosome 4 at 41,725,103 bp
  • T to C, chromosome 4 at 124,686,111 bp
  • A to G, chromosome 4 at 125,691,192 bp
  • T to C, chromosome 4 at 136,290,512 bp
  • T to G, chromosome 4 at 144,715,391 bp
  • A to T, chromosome 4 at 145,624,307 bp
  • T to G, chromosome 5 at 24,595,194 bp
  • T to A, chromosome 5 at 25,258,893 bp
  • T to C, chromosome 5 at 25,375,927 bp
  • A to T, chromosome 5 at 72,503,952 bp
  • A to G, chromosome 5 at 72,782,105 bp
  • A to T, chromosome 5 at 86,499,563 bp
  • C to A, chromosome 5 at 114,131,354 bp
  • C to T, chromosome 5 at 124,750,900 bp
  • A to G, chromosome 5 at 144,173,862 bp
  • T to C, chromosome 6 at 51,466,398 bp
  • T to C, chromosome 6 at 115,274,261 bp
  • A to G, chromosome 6 at 148,355,404 bp
  • T to C, chromosome 7 at 30,482,531 bp
  • A to G, chromosome 7 at 43,024,079 bp
  • G to A, chromosome 7 at 45,049,594 bp
  • G to T, chromosome 7 at 104,142,860 bp
  • A to G, chromosome 7 at 105,385,062 bp
  • T to C, chromosome 7 at 120,089,946 bp
  • T to C, chromosome 7 at 127,487,711 bp
  • T to A, chromosome 7 at 141,863,524 bp
  • T to A, chromosome 8 at 70,913,451 bp
  • C to A, chromosome 8 at 83,365,711 bp
  • T to C, chromosome 8 at 83,730,177 bp
  • T to C, chromosome 8 at 126,444,268 bp
  • A to T, chromosome 9 at 7,826,951 bp
  • G to T, chromosome 9 at 42,461,293 bp
  • T to G, chromosome 9 at 57,027,408 bp
  • T to C, chromosome 9 at 108,966,484 bp
  • T to A, chromosome 10 at 77,935,875 bp
  • T to A, chromosome 10 at 84,947,611 bp
  • C to A, chromosome 10 at 95,413,081 bp
  • A to G, chromosome 10 at 115,390,922 bp
  • T to C, chromosome 11 at 9,134,865 bp
  • A to G, chromosome 11 at 65,895,921 bp
  • G to T, chromosome 11 at 67,815,077 bp
  • A to T, chromosome 11 at 76,846,669 bp
  • A to G, chromosome 11 at 109,434,024 bp
  • T to C, chromosome 12 at 35,086,896 bp
  • A to G, chromosome 12 at 72,790,618 bp
  • G to A, chromosome 13 at 4,576,352 bp
  • A to G, chromosome 13 at 22,328,328 bp
  • A to G, chromosome 13 at 67,772,726 bp
  • G to A, chromosome 13 at 67,783,880 bp
  • T to A, chromosome 13 at 70,798,035 bp
  • G to T, chromosome 13 at 103,743,604 bp
  • T to A, chromosome 13 at 119,466,937 bp
  • A to T, chromosome 15 at 76,602,370 bp
  • A to G, chromosome 15 at 79,289,141 bp
  • T to C, chromosome 15 at 82,620,845 bp
  • C to T, chromosome 16 at 33,117,130 bp
  • T to C, chromosome 16 at 90,760,452 bp
  • A to G, chromosome 17 at 33,920,431 bp
  • T to G, chromosome 18 at 37,321,402 bp
  • A to G, chromosome 19 at 10,477,789 bp
  • A to G, chromosome 19 at 15,924,302 bp
  • T to C, chromosome 19 at 40,962,363 bp
  • T to C, chromosome X at 73,419,860 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1617 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039654-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.