Strain Name:
C57BL/6J-MtgxR1630Btlr/Mmmh
Stock Number:
039667-MU
Citation ID:
RRID:MMRRC_039667-MU
Other Names:
R1630 (G1), C57BL/6J-MtgxR1630Btlr
Major Collection:

Gene Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: 5830426A08Rik, dyn, ROSA62, SpbIV, Spnb4, nmf261, 1700022P15Rik, neuroaxonal dystrophy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80297
Homologene: 11879
Lhx6
Name: LIM homeobox protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16874
Homologene: 7401
Sema6d
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Synonyms: Sema6D-1, 1110067B02Rik, Sema6D-5, Sema6D-4, Sema6D-2, Sema6D-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214968
Homologene: 16195
Nes
Name: nestin
Synonyms: Marc2, RC2, ESTM46, Ifaprc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Npl
Name: N-acetylneuraminate pyruvate lyase
Synonyms: 0610033B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74091
Homologene: 12533
Rad54l2
Name: RAD54 like 2 (S. cerevisiae)
Synonyms: Arip4, Srisnf2l, G630026H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 81000
Homologene: 56698
Atm
Name: ataxia telangiectasia mutated
Synonyms: C030026E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11920
HGNC: HGNC:795
Homologene: 30952
Cdyl
Name: chromodomain protein, Y chromosome-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 12593
VEGA: 13
HGNC: HGNC:1811
Homologene: 3548
Dusp16
Name: dual specificity phosphatase 16
Synonyms: MKP-7, D6Ertd213e, 3830417M17Rik, MKP7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 70686
Homologene: 15604
Nfkbil1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
Synonyms: Def-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18038
HGNC: HGNC:7800
Homologene: 3671
Morc3
Name: microrchidia 3
Synonyms: D16Jhu32e, Zcwcc3, 1110051N18Rik, 1110051N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 338467
Homologene: 32257
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: RA-GEF-2, PDZ-GEF2, Pdzgef2, C030018K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192786
Homologene: 22968
Slain2
Name: SLAIN motif family, member 2
Synonyms: 8030444K12Rik, 5033405K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75991
Homologene: 18952
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
Rttn
Name: rotatin
Synonyms: C530033I08Rik, 4921538A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Ppp1r8
Name: protein phosphatase 1, regulatory subunit 8
Synonyms: NIPP1, 6330548N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100336
HGNC: HGNC:9296
Homologene: 8555
Ttc37
Name: tetratricopeptide repeat domain 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218343
VEGA: 13
Homologene: 40966
Zfp472
Name: zinc finger protein 472
Synonyms: Krim-1A, Krim-1, Krim-1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224691
Homologene: 77422
Lix1
Name: limb and CNS expressed 1
Synonyms: 5730466L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66643
Homologene: 12004
Atp5a1
Name: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Synonyms: Mom2, D18Ertd206e, Atpm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11946
HGNC: HGNC:823
Homologene: 2985
Crispld1
Name: cysteine-rich secretory protein LCCL domain containing 1
Synonyms: Cocoacrisp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 83691
Homologene: 12857
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: perlecan, Pcn, Plc, per
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Kirrel
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Neph1, Kirrel1, 6720469N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 170643
Homologene: 10089
Dapk1
Name: death associated protein kinase 1
Synonyms: D13Ucla1, 2310039H24Rik, DAP-Kinase, 2810425C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: D2Ertd794e, 5830435C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Nobox
Name: NOBOX oogenesis homeobox
Synonyms: Og2x
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18291
Homologene: 51066
F10
Name: coagulation factor X
Synonyms: AI194738, Cf10, fX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14058
HGNC: HGNC:3528
Homologene: 30976
9930012K11Rik
Name: RIKEN cDNA 9930012K11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268759
Homologene: 19540
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328783
VEGA: 17
Homologene: 18633
Dennd4a
Name: DENN/MADD domain containing 4A
Synonyms: F730015K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102442
VEGA: 9
Homologene: 55933
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319555
Homologene: 72261
Osbp2
Name: oxysterol binding protein 2
Synonyms: OSBPL1, C630001G20Rik, ORP-4, 1700095P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74309
HGNC: HGNC:8504
Homologene: 75303
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224572
Homologene: 115024
A630091E08Rik
Name: RIKEN cDNA A630091E08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Mndal
Name: myeloid nuclear differentiation antigen like
Synonyms: Ifi212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040462
HGNC: HGNC:5395
Homologene: 115929
Myocd
Name: myocardin
Synonyms: Srfcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 214384
Homologene: 17043
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Shcbp1
Name: Shc SH2-domain binding protein 1
Synonyms: mPAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20419
Homologene: 32123
Speg
Name: SPEG complex locus
Synonyms: SPEGbeta, SPEG, D1Bwg1450e, Apeg1, SPEGalpha, BPEG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11790
Homologene: 55619
Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Synonyms: Oatp1b2, mlst-1, Slc21a6, Slc21a10, 7330442B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28253
Homologene: 75119
Cyp2c50
Name: cytochrome P450, family 2, subfamily c, polypeptide 50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107141
Homologene: 137231
AC149051.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Zfp963
Name: zinc finger protein 963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 620419
Homologene: 49795
Cactin
Name: cactin, spliceosome C complex subunit
Synonyms: 2510012J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70312
VEGA: 10
Homologene: 69553
Vill
Name: villin-like
Synonyms: Villp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22351
Homologene: 22650
Olfr382
Name: olfactory receptor 382
Synonyms: GA_x6K02T2P1NL-3676608-3675670, MOR135-14, MOR135-31_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258435
Homologene: 17252
4931429P17Rik
Name: RIKEN cDNA 4931429P17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70971
Sgce
Name: sarcoglycan, epsilon
Synonyms: e-SG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20392
Homologene: 31205
Gm12185
Name: predicted gene 12185
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 620913
Homologene: 83188
Ttll11
Name: tubulin tyrosine ligase-like family, member 11
Synonyms: D2Ertd624e, 4933424A20Rik, 4932702F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74410
Homologene: 77534
Masp2
Name: mannan-binding lectin serine peptidase 2
Synonyms: MAp19, MASP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17175
HGNC: HGNC:6902
Homologene: 4819
Olfr1350
Name: olfactory receptor 1350
Synonyms: MOR222-3, GA_x6K02T2QGBW-3300391-3301317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258384
Tmem200a
Name: transmembrane protein 200A
Synonyms: C030003D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77220
VEGA: 10
Homologene: 14175
Olfr1048
Name: olfactory receptor 1048
Synonyms: GA_x6K02T2Q125-47716657-47715716, MOR187-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259016
Morc4
Name: microrchidia 4
Synonyms: 5630401M14Rik, 1600017G11Rik, Zcwcc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 75746
Homologene: 11644
Plrg1
Name: pleiotropic regulator 1
Synonyms: Tango4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 53317
HGNC: HGNC:9089
Homologene: 2004
Tmem106b
Name: transmembrane protein 106B
Synonyms: 5830455K21Rik, 6430519M21Rik, 2310036D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71900
Homologene: 56806
Gm9755
Name: predicted pseudogene 9755
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100041265
Gabrr2
Name: gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14409
HGNC: HGNC:4091
Homologene: 20471
Tmem212
Name: transmembrane protein 212
Synonyms: E030011K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 208613
Homologene: 28471
C1qtnf7
Name: C1q and tumor necrosis factor related protein 7
Synonyms: 8430425G24Rik, CTRP7, 5530401N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 109323
Homologene: 12900
Dnajc5b
Name: DnaJ heat shock protein family (Hsp40) member C5 beta
Synonyms: 1700008A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66326
Homologene: 32634
Ifna1
Name: interferon alpha 1
Synonyms: Ifa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15962
HGNC: HGNC:5425
Homologene: 68536
Rasl10a
Name: RAS-like, family 10, member A
Synonyms: 2210403B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75668
Homologene: 4732
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 17,728,798 bp
  • T to C, chromosome 1 at 75,422,977 bp
  • T to C, chromosome 1 at 153,535,862 bp
  • A to C, chromosome 1 at 173,874,392 bp
  • A to G, chromosome 2 at 35,889,325 bp
  • A to G, chromosome 2 at 36,102,901 bp
  • A to T, chromosome 2 at 60,006,130 bp
  • A to G, chromosome 2 at 86,236,086 bp
  • A to G, chromosome 2 at 124,664,345 bp
  • C to A, chromosome 3 at 19,574,741 bp
  • T to A, chromosome 3 at 27,885,101 bp
  • A to G, chromosome 3 at 83,058,763 bp
  • C to T, chromosome 3 at 87,089,151 bp
  • T to A, chromosome 3 at 87,977,677 bp
  • A to G, chromosome 4 at 33,085,647 bp
  • T to A, chromosome 4 at 88,850,329 bp
  • T to C, chromosome 4 at 132,829,437 bp
  • T to C, chromosome 4 at 137,518,435 bp
  • A to T, chromosome 4 at 148,614,033 bp
  • G to A, chromosome 5 at 43,609,161 bp
  • C to T, chromosome 5 at 72,976,004 bp
  • C to T, chromosome 6 at 4,719,476 bp
  • A to G, chromosome 6 at 13,081,541 bp
  • A to T, chromosome 6 at 43,307,212 bp
  • G to A, chromosome 6 at 48,457,724 bp
  • G to T, chromosome 6 at 134,720,561 bp
  • A to T, chromosome 6 at 141,656,821 bp
  • T to C, chromosome 7 at 6,570,674 bp
  • A to G, chromosome 7 at 27,418,739 bp
  • A to G, chromosome 7 at 98,543,607 bp
  • A to T, chromosome 8 at 4,748,763 bp
  • A to G, chromosome 8 at 13,055,551 bp
  • A to G, chromosome 8 at 63,927,797 bp
  • T to C, chromosome 8 at 67,514,660 bp
  • A to T, chromosome 8 at 69,744,187 bp
  • A to G, chromosome 8 at 72,667,029 bp
  • A to T, chromosome 9 at 53,479,673 bp
  • A to G, chromosome 9 at 64,871,882 bp
  • A to G, chromosome 9 at 106,703,629 bp
  • A to G, chromosome 9 at 119,070,701 bp
  • T to C, chromosome 10 at 25,992,914 bp
  • A to G, chromosome 10 at 81,323,725 bp
  • T to C, chromosome 11 at 3,717,167 bp
  • G to C, chromosome 11 at 5,059,542 bp
  • A to C, chromosome 11 at 48,907,890 bp
  • TG to TGG, chromosome 11 at 54,546,397 bp
  • A to G, chromosome 11 at 65,196,394 bp
  • T to C, chromosome 11 at 73,516,720 bp
  • A to G, chromosome 13 at 35,683,803 bp
  • C to A, chromosome 13 at 47,960,725 bp
  • A to T, chromosome 13 at 60,729,531 bp
  • T to A, chromosome 13 at 76,127,061 bp
  • T to C, chromosome 13 at 95,689,785 bp
  • T to C, chromosome 14 at 70,157,180 bp
  • T to A, chromosome 15 at 47,838,522 bp
  • C to A, chromosome 16 at 93,866,533 bp
  • A to G, chromosome 17 at 17,457,158 bp
  • A to G, chromosome 17 at 19,678,770 bp
  • G to A, chromosome 17 at 25,742,934 bp
  • T to A, chromosome 17 at 32,977,978 bp
  • A to G, chromosome 17 at 35,221,164 bp
  • A to G, chromosome 18 at 77,777,567 bp
  • T to C, chromosome 18 at 89,042,954 bp
  • A to G, chromosome 19 at 40,090,398 bp
  • G to A, chromosome X at 139,837,845 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1630 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039667-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.