Strain Name:
C57BL/6J-MtgxR1653Btlr/Mmmh
Stock Number:
039689-MU
Citation ID:
RRID:MMRRC_039689-MU
Other Names:
R1653 (G1), C57BL/6J-MtgxR1653Btlr
Major Collection:

Gene Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Cdh3
Name: cadherin 3
Synonyms: P-cadherin, Pcad, Cadp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12560
HGNC: HGNC:1762
Homologene: 20425
Myh7
Name: myosin, heavy polypeptide 7, cardiac muscle, beta
Synonyms: Myhc-b, Myhcb, beta-MHC, B-MHC, MYH-beta/slow, MyHC-I, betaMHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 140781
HGNC: HGNC:7577
Homologene: 68044
Slc32a1
Name: solute carrier family 32 (GABA vesicular transporter), member 1
Synonyms: VGAT, R75019, Viaat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22348
Homologene: 56451
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Nrg1
Name: neuregulin 1
Synonyms: HGL, HRG, Hgl, SMDF, GGF, ARIA, heregulin, HRGalpha, D230005F13Rik, 6030402G23Rik, GGFII, NDF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 211323
HGNC: HGNC:7997
Homologene: 138451
Ep400
Name: E1A binding protein p400
Synonyms: p400, mDomino, 1700020J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75560
Homologene: 38779
Wwp2
Name: WW domain containing E3 ubiquitin protein ligase 2
Synonyms: 1300010O06Rik, AIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66894
Homologene: 48490
Kdm5b
Name: lysine (K)-specific demethylase 5B
Synonyms: PLU-1, 2010009J12Rik, Rb-Bp2, Plu1, 2210016I17Rik, D1Ertd202e, Jarid1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75605
Homologene: 48448
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Pdk1
Name: pyruvate dehydrogenase kinase, isoenzyme 1
Synonyms: D530020C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228026
HGNC: HGNC:8809
Homologene: 134437
Sirt1
Name: sirtuin 1
Synonyms: Sir2, Sir2alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 93759
Homologene: 56556
Golga4
Name: golgi autoantigen, golgin subfamily a, 4
Synonyms: golgin-245, Olp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54214
HGNC: HGNC:4427
Homologene: 68224
Sin3b
Name: transcriptional regulator, SIN3B (yeast)
Synonyms: 2810430C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20467
Homologene: 81810
Plk4
Name: polo like kinase 4
Synonyms: Sak, Stk18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20873
Homologene: 7962
Wac
Name: WW domain containing adaptor with coiled-coil
Synonyms: Wwp4, 1110067P07Rik, A230035H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225131
Homologene: 41148
Nfs1
Name: nitrogen fixation gene 1 (S. cerevisiae)
Synonyms: m-Nfs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18041
Homologene: 5463
Bcan
Name: brevican
Synonyms: Cspg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12032
Homologene: 7244
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Klk8
Name: kallikrein related-peptidase 8
Synonyms: BSP1, Prss19, Nrpn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259277
HGNC: HGNC:6369
Homologene: 21410
Tap2
Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: MTP2, PSF2, Ham2, Ham-2, Tap-2, HAM2, Abcb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21355
HGNC: HGNC:44
Homologene: 37323
Gpr183
Name: G protein-coupled receptor 183
Synonyms: Ebi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 321019
VEGA: 14
HGNC: HGNC:3128
Homologene: 28066
Crmp1
Name: collapsin response mediator protein 1
Synonyms: Ulip3, DRP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12933
HGNC: HGNC:2365
Homologene: 20347
N4bp1
Name: NEDD4 binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 80750
Homologene: 23703
Wdcp
Name: WD repeat and coiled coil containing
Synonyms: BC068281
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238037
VEGA: 12
Homologene: 49822
Tmem204
Name: transmembrane protein 204
Synonyms: Clp24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 407831
Homologene: 36419
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: A830096D10Rik, Bai3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Zfyve9
Name: zinc finger, FYVE domain containing 9
Synonyms: Madhip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230597
HGNC: HGNC:6775
Homologene: 3527
Tubgcp6
Name: tubulin, gamma complex associated protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 328580
Homologene: 32477
Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Synonyms: mfmi1, flamingo, EGFL2, Adgrc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 53883
HGNC: HGNC:3231
Homologene: 1078
Gcnt3
Name: glucosaminyl (N-acetyl) transferase 3, mucin type
Synonyms: 2010013H22Rik, 2210021I22Rik, 2210401J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72077
VEGA: 9
HGNC: HGNC:4205
Homologene: 20993
Zfp429
Name: zinc finger protein 429
Synonyms: 2810487A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72807
Homologene: 110878
Zfp839
Name: zinc finger protein 839
Synonyms: 2810455K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72805
VEGA: 12
Homologene: 49541
Ccser1
Name: coiled-coil serine rich 1
Synonyms: 6230405M12Rik, C130092O11Rik, Fam190a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232035
Homologene: 28086
Sugct
Name: succinyl-CoA glutarate-CoA transferase
Synonyms: 5033411D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 192136
VEGA: 13
Homologene: 11681
Pak5
Name: p21 (RAC1) activated kinase 5
Synonyms: Pak5, 2900083L08Rik, Pak7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241656
Homologene: 22211
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Klc4
Name: kinesin light chain 4
Synonyms: 1200014P03Rik, Knsl8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74764
VEGA: 17
Homologene: 12584
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 252866
Homologene: 78104
Capn8
Name: calpain 8
Synonyms: nCL-2', nCL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 170725
HGNC: HGNC:1485
Homologene: 15643
Rdh1
Name: retinol dehydrogenase 1 (all trans)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 107605
Homologene: 129514
Adamts19
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240322
VEGA: 18
Homologene: 15860
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Or56a5
Name: olfactory receptor family 56 subfamily A member 5
Synonyms: GA_x6K02T2PBJ9-7773007-7772066, MOR40-1, Olfr683
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259047
Homologene: 133645
Irs3
Name: insulin receptor substrate 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16369
HGNC: HGNC:6127
Homologene: 84788
Cd276
Name: CD276 antigen
Synonyms: B7-H3, B7RP-2, 6030411F23Rik, B7h3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102657
VEGA: 9
Homologene: 11892
Or4e5
Name: olfactory receptor family 4 subfamily E member 5
Synonyms: GA_x6K02T2RJGY-491851-492792, MOR244-1, MOR28, Olfr1507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57269
HGNC: HGNC:8296
Homologene: 10736
Marchf3
Name: membrane associated ring-CH-type finger 3
Synonyms: 6330411I15Rik, A530081L18Rik, March3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 320253
Homologene: 35310
Casd1
Name: CAS1 domain containing 1
Synonyms: Cast1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213819
Homologene: 11287
Slc35b3
Name: solute carrier family 35, member B3
Synonyms: 4921526O06Rik, PAPST2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 108652
VEGA: 13
Homologene: 9313
Capn10
Name: calpain 10
Synonyms: Capn8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23830
HGNC: HGNC:1477
Homologene: 36323
Igfals
Name: insulin-like growth factor binding protein, acid labile subunit
Synonyms: ALS, Albs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16005
VEGA: 17
HGNC: HGNC:5468
Homologene: 37987
Spaca7
Name: sperm acrosome associated 7
Synonyms: 1700094C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78634
Homologene: 49754
Or14c43
Name: olfactory receptor family 14 subfamily C member 43
Synonyms: GA_x6K02T2NHDJ-9643949-9642957, MOR221-2, Olfr299
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257929
Homologene: 115489
Zrsr1
Name: zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
Synonyms: U2afbp-rs, Irlgs2, D11Ncvs75, 35kDa, SP2, U2af1-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22183
Homologene: 84793
Ndn
Name: necdin, MAGE family member
Synonyms: Peg6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17984
HGNC: HGNC:7675
Homologene: 20559
Lce1h
Name: late cornified envelope 1H
Synonyms: 2310066F03Rik, Sprrl9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67718
9130019O22Rik
Name: RIKEN cDNA 9130019O22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78921
Homologene: 118005
Dctn6
Name: dynactin 6
Synonyms: WS-3, p27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 22428
Homologene: 4792
Gm12258
Name: predicted gene 12258
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 108167848
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 25,101,503 bp
  • A to G, chromosome 1 at 92,946,898 bp
  • T to C, chromosome 1 at 134,602,481 bp
  • A to G, chromosome 1 at 182,623,951 bp
  • G to A, chromosome 2 at 71,888,995 bp
  • A to G, chromosome 2 at 130,935,624 bp
  • C to T, chromosome 2 at 136,116,887 bp
  • C to T, chromosome 2 at 156,125,336 bp
  • A to T, chromosome 2 at 158,614,889 bp
  • T to C, chromosome 3 at 40,810,391 bp
  • T to A, chromosome 3 at 87,994,196 bp
  • T to A, chromosome 3 at 92,763,443 bp
  • T to C, chromosome 3 at 108,413,520 bp
  • G to A, chromosome 4 at 108,660,577 bp
  • A to T, chromosome 4 at 113,490,678 bp
  • T to A, chromosome 5 at 37,286,468 bp
  • G to A, chromosome 5 at 110,693,174 bp
  • C to A, chromosome 5 at 137,644,521 bp
  • T to C, chromosome 6 at 4,624,134 bp
  • T to A, chromosome 6 at 61,311,465 bp
  • G to T, chromosome 7 at 43,803,608 bp
  • C to T, chromosome 7 at 62,348,508 bp
  • T to C, chromosome 7 at 86,466,212 bp
  • T to A, chromosome 7 at 105,143,870 bp
  • G to T, chromosome 7 at 127,384,480 bp
  • T to A, chromosome 8 at 12,586,501 bp
  • C to T, chromosome 8 at 31,818,653 bp
  • G to A, chromosome 8 at 34,092,498 bp
  • A to T, chromosome 8 at 43,650,645 bp
  • G to T, chromosome 8 at 72,741,519 bp
  • G to T, chromosome 8 at 86,844,948 bp
  • T to C, chromosome 8 at 106,539,068 bp
  • T to C, chromosome 8 at 107,483,410 bp
  • T to C, chromosome 9 at 58,537,449 bp
  • A to G, chromosome 9 at 70,035,077 bp
  • C to T, chromosome 9 at 106,072,409 bp
  • T to C, chromosome 9 at 118,568,952 bp
  • T to C, chromosome 10 at 63,321,809 bp
  • T to C, chromosome 10 at 127,764,674 bp
  • T to A, chromosome 11 at 22,974,158 bp
  • T to C, chromosome 11 at 58,858,287 bp
  • T to A, chromosome 11 at 83,346,831 bp
  • T to C, chromosome 12 at 4,851,815 bp
  • T to A, chromosome 12 at 110,855,250 bp
  • T to C, chromosome 13 at 13,635,226 bp
  • T to C, chromosome 13 at 17,671,698 bp
  • A to G, chromosome 13 at 38,955,798 bp
  • C to T, chromosome 13 at 67,389,924 bp
  • A to G, chromosome 14 at 31,149,036 bp
  • A to T, chromosome 14 at 52,490,772 bp
  • A to G, chromosome 14 at 54,990,789 bp
  • A to G, chromosome 14 at 121,954,263 bp
  • T to A, chromosome 15 at 35,607,272 bp
  • G to A, chromosome 15 at 89,107,442 bp
  • T to C, chromosome 17 at 24,881,078 bp
  • A to G, chromosome 17 at 25,080,527 bp
  • T to A, chromosome 17 at 34,209,303 bp
  • T to C, chromosome 17 at 46,631,859 bp
  • T to A, chromosome 18 at 7,917,623 bp
  • A to G, chromosome 18 at 56,811,895 bp
  • T to A, chromosome 18 at 58,890,293 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1653 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039689-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.