Strain Name:
C57BL/6J-MtgxR1706Btlr/Mmmh
Stock Number:
039739-MU
Citation ID:
RRID:MMRRC_039739-MU
Other Names:
R1706 (G1), C57BL/6J-MtgxR1706Btlr
Major Collection:

Gene Information

Pygb
Name: brain glycogen phosphorylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 110078
HGNC: HGNC:9723
Homologene: 100930
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Luc7l3
Name: LUC7-like 3 (S. cerevisiae)
Synonyms: 3300001P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67684
Homologene: 75056
Rab30
Name: RAB30, member RAS oncogene family
Synonyms: 5033421K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75985
HGNC: HGNC:9770
Homologene: 22815
Clcn6
Name: chloride channel, voltage-sensitive 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26372
HGNC: HGNC:2024
Homologene: 985
Ctage5
Name: CTAGE family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Kif13b
Name: kinesin family member 13B
Synonyms: GAKIN, N-3 kinesin, C130021D12Rik, 5330429L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16554
VEGA: 14
Homologene: 9073
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Cenpc1
Name: centromere protein C1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12617
HGNC: HGNC:1854
Homologene: 1371
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, D9Ertd809e, Dopey1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320615
Homologene: 26645
Ago3
Name: argonaute RISC catalytic subunit 3
Synonyms: argonaute 3, eIF2C3, C130014L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214150
Homologene: 49799
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki-67, D630048A14Rik, Ki67
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Akap8l
Name: A kinase (PRKA) anchor protein 8-like
Synonyms: Nakap95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 54194
VEGA: 17
Homologene: 8658
Zzz3
Name: zinc finger, ZZ domain containing 3
Synonyms: 3110065C23Rik, 6430567E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 108946
Homologene: 9182
Zfp868
Name: zinc finger protein 868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234362
Homologene: 74376
Cdan1
Name: congenital dyserythropoietic anemia, type I (human)
Synonyms: CDA-I, CDA1, 1500015A01Rik, codanin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68968
HGNC: HGNC:1713
Homologene: 16324
Smurf2
Name: SMAD specific E3 ubiquitin protein ligase 2
Synonyms: 2810411E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66313
Homologene: 41490
Pcdhb16
Name: protocadherin beta 16
Synonyms: PcdhbP, Pcdhb8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93887
HGNC: HGNC:8693
Homologene: 99843
4931406C07Rik
Name: RIKEN cDNA 4931406C07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70984
VEGA: 9
Homologene: 8531
Ttc8
Name: tetratricopeptide repeat domain 8
Synonyms: 0610012F22Rik, BBS8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76260
Homologene: 14988
Kcnn4
Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Synonyms: SK4, IK1, mIKCa1, IKCa1, KCa3.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16534
HGNC: HGNC:6293
Homologene: 1696
Cfap206
Name: cilia and flagella associated protein 206
Synonyms: 1700003M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69329
Homologene: 18713
Rab44
Name: RAB44, member RAS oncogene family
Synonyms: 9830134C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 442827
Homologene: 53300
Rsc1a1
Name: regulatory solute carrier protein, family 1, member 1
Synonyms: RS1, mRS1, OTTMUSG00000010365
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69994
Homologene: 130554
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Duox1
Name: dual oxidase 1
Synonyms: NOXEF1, THOX1, LNOX1, 9930101G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Trim67
Name: tripartite motif-containing 67
Synonyms: D130049O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330863
Homologene: 45699
Sema5b
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Synonyms: SemG, SemG, Semag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20357
Homologene: 8427
Cyp2d10
Name: cytochrome P450, family 2, subfamily d, polypeptide 10
Synonyms: P450-2D, Cyp2d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13101
VEGA: 15
Homologene: 86099
Tex10
Name: testis expressed gene 10
Synonyms: clone 18330, 2810462N03Rik, 2610206N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269536
Homologene: 32361
Cav1
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12389
HGNC: HGNC:1527
Homologene: 1330
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17837
Homologene: 136663
Rccd1
Name: RCC1 domain containing 1
Synonyms: E430018M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269955
Homologene: 16782
Cstl1
Name: cystatin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228756
Homologene: 16283
Tmprss9
Name: transmembrane protease, serine 9
Synonyms: Serase-1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432478
VEGA: 10
Homologene: 115302
Ercc6l2
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
Synonyms: 1700019D06Rik, 9330134C04Rik, 0610007P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76251
Homologene: 32564
Vmn2r7
Name: vomeronasal 2, receptor 7
Synonyms: 4933425M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 319217
Homologene: 129754
Tgm6
Name: transglutaminase 6
Synonyms: TGM3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241636
Homologene: 27970
Lypd3
Name: Ly6/Plaur domain containing 3
Synonyms: C4.4A, 2310061G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72434
Homologene: 8672
Syt10
Name: synaptotagmin X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54526
Homologene: 10303
Olfr1099
Name: olfactory receptor 1099
Synonyms: GA_x6K02T2Q125-48446067-48445129, MOR206-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258764
Homologene: 107003
Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Synonyms: SNS2, NaN, NaT, NSS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 24046
VEGA: 9
Homologene: 8041
Slc22a14
Name: solute carrier family 22 (organic cation transporter), member 14
Synonyms: LOC382113
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382113
HGNC: HGNC:8495
Homologene: 3530
C1ra
Name: complement component 1, r subcomponent A
Synonyms: mC1rA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 50909
HGNC: HGNC:1246
Homologene: 1313
Gpatch3
Name: G patch domain containing 3
Synonyms: D930035B09Rik, Gpatc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242691
Homologene: 11122
Gm7052
Name: predicted gene 7052
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 631010
Pak1ip1
Name: PAK1 interacting protein 1
Synonyms: 5830431I15Rik, 5930415H02Rik, p21-activated protein kinase-interacting protein 1, PIP1, Gdpd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68083
Homologene: 39574
Neu3
Name: neuraminidase 3
Synonyms: membrane sialidase, ganglioside sialidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 50877
HGNC: HGNC:7760
Homologene: 4847
D130052B06Rik
Name: RIKEN cDNA D130052B06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216644
VEGA: 11
Igsf8
Name: immunoglobulin superfamily, member 8
Synonyms: ESTM34, EWI-2, PG regulatory-like protein, PGRL, KCT-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 140559
Homologene: 14163
BC005624
Name: cDNA sequence BC005624
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227707
Homologene: 9551
Mchr1
Name: melanin-concentrating hormone receptor 1
Synonyms: melanin-concentrating hormone receptor 1, MCH-1R, Gpr24-9, Mch1r, Gpr24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 207911
VEGA: 15
HGNC: HGNC:4479
Homologene: 21097
Lca5l
Name: Leber congenital amaurosis 5-like
Synonyms: 4921526F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 385668
HGNC: HGNC:1255
Homologene: 47978
Ak8
Name: adenylate kinase 8
Synonyms: 1190002A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68870
Homologene: 17622
Kcnh3
Name: potassium voltage-gated channel, subfamily H (eag-related), member 3
Synonyms: ether a go-go like, Elk2, Melk2, C030044P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16512
VEGA: 15
HGNC: HGNC:6252
Homologene: 32150
4921524L21Rik
Name: RIKEN cDNA 4921524L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70901
VEGA: 18
Homologene: 78009
Gnas
Name: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
Synonyms: Gnas1, Gs-alpha, Gs alpha, G alpha s, Nesp55, P2, P3, P1, Gsa, neuroendocrine-specific Golgi protein p55 isoform 1, XLalphas, Nesp, Gnasxl, Nespl, Oedsml, Galphas, SCG6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14683
HGNC: HGNC:4392
Homologene: 55534
Olfr1198
Name: olfactory receptor 1198
Synonyms: GA_x6K02T2Q125-50221692-50220766, MOR225-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404330
Homologene: 138634
Ugt1a7c
Name: UDP glucuronosyltransferase 1 family, polypeptide A7C
Synonyms: A10'
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 394432
Homologene: 136043
Zfp511
Name: zinc finger protein 511
Synonyms: 2410004P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69752
Homologene: 42950
Gm9925
Name: predicted gene 9925
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 433202
VEGA: 18
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 88,095,725 bp
  • C to T, chromosome 1 at 172,317,405 bp
  • T to C, chromosome 2 at 28,759,995 bp
  • T to C, chromosome 2 at 30,978,910 bp
  • A to T, chromosome 2 at 86,959,080 bp
  • G to A, chromosome 2 at 88,746,138 bp
  • G to T, chromosome 2 at 120,718,933 bp
  • A to G, chromosome 2 at 122,319,472 bp
  • T to C, chromosome 2 at 130,145,159 bp
  • G to A, chromosome 2 at 148,751,159 bp
  • G to A, chromosome 2 at 150,827,147 bp
  • T to A, chromosome 2 at 174,299,975 bp
  • T to A, chromosome 3 at 64,691,459 bp
  • T to A, chromosome 3 at 152,449,098 bp
  • G to A, chromosome 4 at 34,688,875 bp
  • C to T, chromosome 4 at 48,456,800 bp
  • A to G, chromosome 4 at 123,370,584 bp
  • G to A, chromosome 4 at 126,370,292 bp
  • T to A, chromosome 4 at 133,575,173 bp
  • A to G, chromosome 4 at 141,683,997 bp
  • G to A, chromosome 4 at 148,017,568 bp
  • G to A, chromosome 5 at 86,016,192 bp
  • T to C, chromosome 6 at 17,339,182 bp
  • T to A, chromosome 6 at 122,036,228 bp
  • T to A, chromosome 6 at 122,036,232 bp
  • G to T, chromosome 6 at 124,517,521 bp
  • T to A, chromosome 7 at 24,374,742 bp
  • T to C, chromosome 7 at 24,640,330 bp
  • C to G, chromosome 7 at 80,320,663 bp
  • A to T, chromosome 7 at 92,829,667 bp
  • A to G, chromosome 7 at 99,823,356 bp
  • A to G, chromosome 7 at 135,700,566 bp
  • A to G, chromosome 7 at 140,037,279 bp
  • A to G, chromosome 8 at 69,612,409 bp
  • A to G, chromosome 8 at 124,794,421 bp
  • G to A, chromosome 9 at 15,297,857 bp
  • C to T, chromosome 9 at 86,554,080 bp
  • A to G, chromosome 9 at 110,549,864 bp
  • T to C, chromosome 9 at 119,180,984 bp
  • A to C, chromosome 9 at 119,770,400 bp
  • T to C, chromosome 10 at 80,898,187 bp
  • G to A, chromosome 11 at 33,616,230 bp
  • T to C, chromosome 11 at 94,297,756 bp
  • G to A, chromosome 11 at 106,824,747 bp
  • T to A, chromosome 12 at 59,144,766 bp
  • C to A, chromosome 12 at 98,943,883 bp
  • T to C, chromosome 13 at 41,012,688 bp
  • T to A, chromosome 13 at 63,872,458 bp
  • T to A, chromosome 13 at 68,720,746 bp
  • T to A, chromosome 14 at 64,760,666 bp
  • A to G, chromosome 15 at 81,237,163 bp
  • A to C, chromosome 15 at 82,405,582 bp
  • C to T, chromosome 15 at 89,790,776 bp
  • A to G, chromosome 15 at 99,238,078 bp
  • T to C, chromosome 16 at 35,649,755 bp
  • T to C, chromosome 16 at 96,175,964 bp
  • A to G, chromosome 17 at 22,039,842 bp
  • C to A, chromosome 17 at 29,138,106 bp
  • C to T, chromosome 17 at 32,332,483 bp
  • T to C, chromosome 18 at 6,624,059 bp
  • A to G, chromosome 18 at 37,479,652 bp
  • G to A, chromosome 18 at 74,065,502 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1706 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039739-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.