Strain Name:
C57BL/6J-MtgxR1724Btlr/Mmmh
Stock Number:
039756-MU
Citation ID:
RRID:MMRRC_039756-MU
Other Names:
R1724 (G1), C57BL/6J-MtgxR1724Btlr
Major Collection:

Gene Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231051
Homologene: 46480
Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: Fadk, FAK, FRNK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Sema7a
Name: sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
Synonyms: Semaphorin K1, CDw108, Semal, 2900057C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20361
VEGA: 9
Homologene: 2678
Nes
Name: nestin
Synonyms: RC2, Marc2, ESTM46, Ifaprc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, SBP2, 2810012K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75420
Homologene: 11415
Kifap3
Name: kinesin-associated protein 3
Synonyms: KAP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16579
Homologene: 7799
Washc4
Name: WASH complex subunit 4
Synonyms: A230046K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 319277
VEGA: 10
Homologene: 123926
Slc37a3
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 3
Synonyms: 2610507O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 72144
Homologene: 41740
Dhx9
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 9
Synonyms: leukophysin, nuclear DNA helicase II, RNA helicase, Ddx9, NDH II, NDHII, RHA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13211
HGNC: HGNC:2750
Homologene: 1039
Taf3
Name: TATA-box binding protein associated factor 3
Synonyms: mTAFII140, 4933439M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 209361
Homologene: 35415
Gsk3b
Name: glycogen synthase kinase 3 beta
Synonyms: GSK-3beta, GSK-3, 8430431H08Rik, 7330414F15Rik, GSK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56637
HGNC: HGNC:4617
Homologene: 55629
Gabpb2
Name: GA repeat binding protein, beta 2
Synonyms: 9430006E19Rik, Gabpb2-1, A430024B14Rik, 1810015F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213054
Homologene: 34921
Zfp292
Name: zinc finger protein 292
Synonyms: Zn-16, Zn-15, Krox-10, Zfp-15, 9430062L07Rik, 5730450D02Rik, Zfp15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Bcdin3d
Name: BCDIN3 domain containing
Synonyms: 4930556P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75284
VEGA: 15
Homologene: 12594
Lmbr1
Name: limb region 1
Synonyms: 1110048D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56873
Homologene: 49706
Ifitm1
Name: interferon induced transmembrane protein 1
Synonyms: fragilis2, Mil2, 1110036C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68713
HGNC: HGNC:5412
Homologene: 135938
Creld1
Name: cysteine-rich with EGF-like domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171508
Homologene: 32265
Sdc4
Name: syndecan 4
Synonyms: ryudocan, Synd4, syndecan-4, S4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20971
Homologene: 31121
Ddah1
Name: dimethylarginine dimethylaminohydrolase 1
Synonyms: 2410006N07Rik, 2510015N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69219
HGNC: HGNC:2715
Homologene: 8120
Arap1
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Synonyms: 2410002L19Rik, Centd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69710
Homologene: 12326
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240255
Homologene: 11265
Adamts13
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
Synonyms: LOC279028, vWF-CP mRNA for von Willebrand factor-cleaving
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Col9a2
Name: collagen, type IX, alpha 2
Synonyms: Col9a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12840
HGNC: HGNC:2218
Homologene: 37535
Or52h9
Name: olfactory receptor family 52 subfamily H member 9
Synonyms: GA_x6K02T2PBJ9-7179540-7180481, MOR31-11, Olfr651
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258809
Homologene: 64922
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: Mlsn1, 4732499L03Rik, melastatin, LTRPC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319555
Homologene: 72261
Auh
Name: AU RNA binding protein/enoyl-coenzyme A hydratase
Synonyms: W91705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11992
HGNC: HGNC:890
Homologene: 1284
Perm1
Name: PPARGC1 and ESRR induced regulator, muscle 1
Synonyms: 2310042D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74183
Homologene: 135954
Galntl5
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
Synonyms: 1700021B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67909
Homologene: 12210
Trpm8
Name: transient receptor potential cation channel, subfamily M, member 8
Synonyms: CMR1, TRPP8, Trp-p8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 171382
Homologene: 23433
Spag16
Name: sperm associated antigen 16
Synonyms: Pf20, 4930524F24Rik, 4930585K05Rik, Wdr29, 4921511D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66722
Homologene: 11572
Thbs2
Name: thrombospondin 2
Synonyms: TSP2, Thbs-2, Thrombospondin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Osgepl1
Name: O-sialoglycoprotein endopeptidase-like 1
Synonyms: MGC13061, 2610001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72085
Homologene: 5561
Sun1
Name: Sad1 and UNC84 domain containing 1
Synonyms: 4632417G13Rik, 5730434D03Rik, Unc84a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77053
Homologene: 11544
Gabrr1
Name: gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
Synonyms: GABA-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14408
HGNC: HGNC:4090
Homologene: 20470
Fam83f
Name: family with sequence similarity 83, member F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 213956
VEGA: 15
Homologene: 16313
Hectd2
Name: HECT domain E3 ubiquitin protein ligase 2
Synonyms: A630025O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226098
Homologene: 6280
Cth
Name: cystathionase (cystathionine gamma-lyase)
Synonyms: 0610010I13Rik, CSE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 107869
HGNC: HGNC:2501
Homologene: 1432
Col10a1
Name: collagen, type X, alpha 1
Synonyms: Col10a-1, Col10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12813
HGNC: HGNC:2185
Homologene: 55466
Atg4d
Name: autophagy related 4D, cysteine peptidase
Synonyms: APG4-D, 9830134P12Rik, Autl4, Apg4d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235040
VEGA: 9
Homologene: 13156
Zc2hc1c
Name: zinc finger, C2HC-type containing 1C
Synonyms: 2810002I04Rik, Fam164c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72350
Homologene: 23461
BC007180
Name: cDNA sequence BC007180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Gm15409
Name: predicted gene 15409
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Lce1l
Name: late cornified envelope 1L
Synonyms: 1110008K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73730
Olfr715b
Name: olfactory receptor 715B
Synonyms: EG384732, Gm10081
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384732
HGNC: HGNC:8244
Homologene: 81541
Gm5356
Name: predicted pseudogene 5356
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 384862
AC124409.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Gm10277
Name: predicted gene 10277
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 791303
Cep295nl
Name: CEP295 N-terminal like
Synonyms: Ddc8, BC100451
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58251
Homologene: 75164
Dazap2
Name: DAZ associated protein 2
Synonyms: gt6-12, Brbp, Prtb, Gcap28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 23994
VEGA: 15
HGNC: HGNC:2684
Homologene: 8038
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 53,317,903 bp
  • G to C, chromosome 1 at 70,493,782 bp
  • A to T, chromosome 1 at 88,350,856 bp
  • A to C, chromosome 1 at 153,458,488 bp
  • C to T, chromosome 1 at 163,783,097 bp
  • A to G, chromosome 2 at 9,952,366 bp
  • T to C, chromosome 2 at 26,991,294 bp
  • G to T, chromosome 2 at 164,431,286 bp
  • C to A, chromosome 3 at 87,977,441 bp
  • A to T, chromosome 3 at 92,850,419 bp
  • T to C, chromosome 3 at 95,206,515 bp
  • A to C, chromosome 3 at 145,891,506 bp
  • T to A, chromosome 3 at 154,762,327 bp
  • A to T, chromosome 3 at 157,913,727 bp
  • T to A, chromosome 4 at 33,161,651 bp
  • C to A, chromosome 4 at 34,811,237 bp
  • G to A, chromosome 4 at 121,053,902 bp
  • C to T, chromosome 4 at 143,993,432 bp
  • T to C, chromosome 4 at 156,218,072 bp
  • T to G, chromosome 5 at 25,220,122 bp
  • C to T, chromosome 5 at 25,315,005 bp
  • T to A, chromosome 5 at 29,361,083 bp
  • T to A, chromosome 5 at 139,235,725 bp
  • C to A, chromosome 5 at 148,959,501 bp
  • A to G, chromosome 6 at 39,344,238 bp
  • A to G, chromosome 6 at 113,484,574 bp
  • G to T, chromosome 7 at 64,235,821 bp
  • G to T, chromosome 7 at 101,400,526 bp
  • T to C, chromosome 7 at 104,553,228 bp
  • G to A, chromosome 7 at 107,106,202 bp
  • T to A, chromosome 7 at 140,969,484 bp
  • A to C, chromosome 8 at 72,711,620 bp
  • G to A, chromosome 8 at 89,187,056 bp
  • C to A, chromosome 8 at 110,110,163 bp
  • C to T, chromosome 9 at 21,268,445 bp
  • C to A, chromosome 9 at 57,954,627 bp
  • A to G, chromosome 10 at 34,395,718 bp
  • T to C, chromosome 10 at 83,576,008 bp
  • TC to T, chromosome 11 at 77,786,002 bp
  • T to A, chromosome 11 at 118,333,028 bp
  • G to T, chromosome 12 at 85,289,812 bp
  • A to G, chromosome 13 at 51,670,846 bp
  • G to A, chromosome 13 at 52,835,496 bp
  • A to G, chromosome 15 at 73,242,406 bp
  • T to G, chromosome 15 at 80,692,267 bp
  • T to A, chromosome 15 at 99,470,680 bp
  • T to A, chromosome 15 at 100,618,003 bp
  • T to A, chromosome 16 at 38,144,468 bp
  • A to G, chromosome 17 at 14,685,900 bp
  • T to C, chromosome 18 at 44,828,690 bp
  • A to G, chromosome 19 at 36,587,440 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1724 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039756-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.