Strain Name:
C57BL/6J-MtgxR1748Btlr/Mmmh
Stock Number:
039780-MU
Citation ID:
RRID:MMRRC_039780-MU
Other Names:
R1748 (G1), C57BL/6J-MtgxR1748Btlr
Major Collection:

Gene Information

Espl1
Name: extra spindle pole bodies 1, separase
Synonyms: separase, PRCE, PRCE, ESP1, SSE, Cerp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105988
VEGA: 15
Homologene: 32151
Psen2
Name: presenilin 2
Synonyms: Ad4h, PS-2, ALG-3, PS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19165
HGNC: HGNC:9509
Homologene: 386
Vsx2
Name: visual system homeobox 2
Synonyms: Hox-10, Hox10, Chx10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 12677
HGNC: HGNC:1975
Homologene: 7266
Lgals8
Name: lectin, galactose binding, soluble 8
Synonyms: D13Ertd524e, Lgals-8, 1200015E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 56048
HGNC: HGNC:6569
Homologene: 31386
Kl
Name: klotho
Synonyms: alpha-kl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16591
HGNC: HGNC:6344
Homologene: 68415
Ndrg1
Name: N-myc downstream regulated gene 1
Synonyms: CMT4D, Ndrl, Tdd5, DRG1, TDD5, CAP43, PROXY1, Ndr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17988
HGNC: HGNC:7679
Homologene: 55953
Capzb
Name: capping protein (actin filament) muscle Z-line, beta
Synonyms: CPB2, 1700120C01Rik, CPbeta1, Cappb1, CPB1, CPbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12345
HGNC: HGNC:1491
Homologene: 3620
Scarb2
Name: scavenger receptor class B, member 2
Synonyms: Cd36l2, 9330185J12Rik, LGP85, LIMP II, LIMP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12492
HGNC: HGNC:1665
Homologene: 48353
Map3k8
Name: mitogen-activated protein kinase kinase kinase 8
Synonyms: Tpl2, Tpl-2, c-COT, Cot/Tpl2, Cot
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 26410
HGNC: HGNC:6860
Homologene: 3812
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 277854
Homologene: 34718
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: rjs, D7H15F37S1, jdf2, D7H15F32S1, D15F32S1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Eif3a
Name: eukaryotic translation initiation factor 3, subunit A
Synonyms: Eif3s10, Csma, Eif3, A830012B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13669
VEGA: 19
HGNC: HGNC:3271
Homologene: 2779
Rif1
Name: replication timing regulatory factor 1
Synonyms: D2Ertd145e, 5730435J01Rik, 6530403D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51869
Homologene: 41231
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 208836
Homologene: 49530
Abcc5
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 5
Synonyms: 2900011L11Rik, Mrp5, Abcc5b, Abcc5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Ccser2
Name: coiled-coil serine rich 2
Synonyms: 2900054P12Rik, 1700012P13Rik, Gcap14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 72972
Homologene: 10367
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 404710
Homologene: 26400
Ube2c
Name: ubiquitin-conjugating enzyme E2C
Synonyms: D2Ertd695e, 1110015A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68612
Homologene: 5096
Tpbg
Name: trophoblast glycoprotein
Synonyms: 5T4 oncofetal antigen, 5T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21983
Homologene: 4859
Adamts12
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239337
VEGA: 15
Homologene: 12808
Ccnb1
Name: cyclin B1
Synonyms: Ccnb1-rs13, Cycb-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 268697
HGNC: HGNC:1579
Homologene: 68982
Aire
Name: autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11634
HGNC: HGNC:360
Homologene: 327
Tm9sf3
Name: transmembrane 9 superfamily member 3
Synonyms: Smbp, 2810031D16Rik, 1810073M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107358
VEGA: 19
Homologene: 10588
Anpep
Name: alanyl (membrane) aminopeptidase
Synonyms: Apn, Cd13, aminopeptidase N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Sag
Name: S-antigen, retina and pineal gland (arrestin)
Synonyms: arrestin 1, A930001K18Rik, visual arrestin 1, Arr1, rod arrestin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20215
Homologene: 455
Spata24
Name: spermatogenesis associated 24
Synonyms: TIPT, 2700012K08Rik, 4930583E11Rik, TIPT2, 5133400G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 71242
VEGA: 18
Homologene: 32688
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, mKIAA0811, LOC245827, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Tas2r113
Name: taste receptor, type 2, member 113
Synonyms: T2R13, Tas2r13, mt2r58, mGR13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387345
Homologene: 130075
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: sba, 1700096C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240411
Vmn1r78
Name: vomeronasal 1 receptor 78
Synonyms: V1rg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171242
Homologene: 74316
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Prmt6
Name: protein arginine N-methyltransferase 6
Synonyms: Hrmt1l6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99890
Homologene: 10024
Duox2
Name: dual oxidase 2
Synonyms: A430065P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 214593
Homologene: 9689
Atp2a1
Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Synonyms: SERCA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11937
HGNC: HGNC:811
Homologene: 7635
Capn3
Name: calpain 3
Synonyms: Capa-3, p94, Capa3, Lp82
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12335
HGNC: HGNC:1480
Homologene: 52
Slc36a1
Name: solute carrier family 36 (proton/amino acid symporter), member 1
Synonyms: 5830411H19Rik, Pat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215335
Homologene: 121860
Hltf
Name: helicase-like transcription factor
Synonyms: P113, Snf2l3, Smarca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20585
Homologene: 30136
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: CMF608, 6530405F15Rik, Adlican2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242050
Homologene: 18712
Tmem144
Name: transmembrane protein 144
Synonyms: 5730537D05Rik, 1110057I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70652
Homologene: 41250
Sh3pxd2b
Name: SH3 and PX domains 2B
Synonyms: Fad49, Tsk4, G431001E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268396
Homologene: 27952
Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Synonyms: 1110036I10Rik, Nh, VRL3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 246788
Homologene: 17040
Vmn2r114
Name: vomeronasal 2, receptor 114
Synonyms: EG666002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 666002
Homologene: 86604
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226255
VEGA: 19
Homologene: 45809
Plcl2
Name: phospholipase C-like 2
Synonyms: Plce2, PRIP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224860
VEGA: 17
HGNC: HGNC:9064
Homologene: 9052
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cchra1, alpha1E, Cav2.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Notch4
Name: notch 4
Synonyms: Int-3, Int3, N4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18132
HGNC: HGNC:7884
Homologene: 3351
Ces2h
Name: carboxylesterase 2H
Synonyms: Gm5744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 436059
HGNC: HGNC:1864
Homologene: 128645
Bpifb6
Name: BPI fold containing family B, member 6
Synonyms: LOC228796, Bpil3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228796
Homologene: 18375
Alk
Name: anaplastic lymphoma kinase
Synonyms: CD246, Tcrz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 11682
VEGA: 17
HGNC: HGNC:427
Homologene: 68387
Gpr108
Name: G protein-coupled receptor 108
Synonyms: 1810015L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78308
VEGA: 17
Homologene: 32495
Ddx28
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
Synonyms: Mddx28, 2410004K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71986
Homologene: 10164
Mybphl
Name: myosin binding protein H-like
Synonyms: 1110037P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68753
Homologene: 19221
Smg8
Name: smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
Synonyms: 1200011M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74133
Homologene: 32393
Erbb2
Name: erb-b2 receptor tyrosine kinase 2
Synonyms: HER-2, ErbB-2, Neu oncogene, c-neu, HER2, c-erbB2, Neu, l11Jus8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13866
HGNC: HGNC:3430
Homologene: 3273
Aldh3b2
Name: aldehyde dehydrogenase 3 family, member B2
Synonyms: C130048D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 621603
HGNC: HGNC:411
Homologene: 84430
Ano8
Name: anoctamin 8
Synonyms: Tmem16h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382014
Homologene: 124473
Ogg1
Name: 8-oxoguanine DNA-glycosylase 1
Synonyms: Mmh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18294
HGNC: HGNC:8125
Homologene: 1909
Arsk
Name: arylsulfatase K
Synonyms: 2810429K17Rik, 4833414G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 77041
Homologene: 12670
Slc5a7
Name: solute carrier family 5 (choline transporter), member 7
Synonyms: CHT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 63993
VEGA: 17
Homologene: 32516
Rab3il1
Name: RAB3A interacting protein (rabin3)-like 1
Synonyms: Rab3ail1, 1200014K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 74760
HGNC: HGNC:9780
Homologene: 40880
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225288
VEGA: 18
Homologene: 45323
BC017158
Name: cDNA sequence BC017158
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233913
Homologene: 11232
Fam166a
Name: family with sequence similarity 166, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68222
Homologene: 12247
Cr2
Name: complement receptor 2
Synonyms: C3DR, CD21, Cr-2, Cr1, CD35, Cr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Olfr138
Name: olfactory receptor 138
Synonyms: Olfr89, MOR256-40P, GA_x6K02T2PSCP-2718585-2719523
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 170648
Homologene: 119758
Ikbke
Name: inhibitor of kappaB kinase epsilon
Synonyms: IKK-i, IKKepsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 56489
Homologene: 23168
Gm16286
Name: predicted gene 16286
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
Ccdc68
Name: coiled-coil domain containing 68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 381175
Homologene: 11880
Dok5
Name: docking protein 5
Synonyms: 2700055C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76829
Homologene: 10195
Zpld2
Name: zona pellucida like domain containing 2
Synonyms: Gm7534
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 665186
Homologene: 104039
Wars2
Name: tryptophanyl tRNA synthetase 2 (mitochondrial)
Synonyms: TrpRS, 9430020O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70560
Homologene: 5673
Siae
Name: sialic acid acetylesterase
Synonyms: LSE, clone 165, Ysg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22619
Homologene: 8001
Polr3d
Name: polymerase (RNA) III (DNA directed) polypeptide D
Synonyms: RPC4, 2810426M17Rik, BN51T, 44kDa, TSBN51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 67065
VEGA: 14
HGNC: HGNC:1080
Homologene: 1303
Asgr2
Name: asialoglycoprotein receptor 2
Synonyms: Asgr, ASGPR2, Asgr-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11890
HGNC: HGNC:743
Homologene: 912
Hepacam
Name: hepatocyte cell adhesion molecule
Synonyms: Glialcam, 2900042E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72927
Homologene: 17652
Lmcd1
Name: LIM and cysteine-rich domains 1
Synonyms: dyxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 30937
HGNC: HGNC:6633
Homologene: 22823
Hao1
Name: hydroxyacid oxidase 1, liver
Synonyms: GOX, Hao-1, Gox1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15112
HGNC: HGNC:4809
Homologene: 6578
Dld
Name: dihydrolipoamide dehydrogenase
Synonyms: branched chain alpha-keto acid dehydrogenase complex subunit E3, dihydrolipoyl dehydrogenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 13382
VEGA: 12
HGNC: HGNC:2898
Homologene: 84
Gm17305
Name: predicted gene, 17305
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
Lgalsl
Name: lectin, galactoside binding-like
Synonyms: 1110067D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216551
Homologene: 8581
Sap25
Name: sin3 associated polypeptide
Synonyms: 25 kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 751865
Homologene: 104044
Tmem45a
Name: transmembrane protein 45a
Synonyms: C630002M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 56277
Homologene: 41215
Agrp
Name: agouti related neuropeptide
Synonyms: agouti related protein, Agrt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11604
HGNC: HGNC:330
Homologene: 7184
Lrrc73
Name: leucine rich repeat containing 73
Synonyms: Gm88, LOC224813
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224813
VEGA: 17
Homologene: 19183
Olfr885
Name: olfactory receptor 885
Synonyms: GA_x6K02T2PVTD-31740639-31741568, MOR162-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 257885
Homologene: 79400
M5C1000I18Rik
Name: RIKEN cDNA M5C1000I18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102633151
Pbx2
Name: pre B cell leukemia homeobox 2
Synonyms: G17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18515
HGNC: HGNC:8633
Homologene: 48115
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 87,831,940 bp
  • G to T, chromosome 1 at 131,259,200 bp
  • A to T, chromosome 1 at 154,486,569 bp
  • C to T, chromosome 1 at 180,238,863 bp
  • T to A, chromosome 1 at 195,155,905 bp
  • G to A, chromosome 2 at 25,220,443 bp
  • T to A, chromosome 2 at 41,728,706 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • T to C, chromosome 2 at 120,497,013 bp
  • T to C, chromosome 2 at 122,287,051 bp
  • T to A, chromosome 2 at 134,498,318 bp
  • T to C, chromosome 2 at 153,910,709 bp
  • T to C, chromosome 2 at 164,771,321 bp
  • T to A, chromosome 2 at 170,841,453 bp
  • T to C, chromosome 3 at 20,076,521 bp
  • A to T, chromosome 3 at 59,319,093 bp
  • C to T, chromosome 3 at 79,825,287 bp
  • A to G, chromosome 3 at 88,113,980 bp
  • A to T, chromosome 3 at 99,141,068 bp
  • A to T, chromosome 3 at 108,375,084 bp
  • T to C, chromosome 3 at 110,250,367 bp
  • C to G, chromosome 4 at 134,200,299 bp
  • T to A, chromosome 4 at 134,202,119 bp
  • C to A, chromosome 4 at 139,257,368 bp
  • A to G, chromosome 5 at 32,917,942 bp
  • A to G, chromosome 5 at 92,460,836 bp
  • T to A, chromosome 5 at 137,641,918 bp
  • T to C, chromosome 5 at 150,980,985 bp
  • T to C, chromosome 6 at 112,329,914 bp
  • T to C, chromosome 6 at 113,333,621 bp
  • A to T, chromosome 6 at 132,893,732 bp
  • T to A, chromosome 7 at 12,153,323 bp
  • T to C, chromosome 7 at 56,148,823 bp
  • T to C, chromosome 7 at 79,430,488 bp
  • C to T, chromosome 7 at 79,838,256 bp
  • A to G, chromosome 7 at 126,459,608 bp
  • A to G, chromosome 7 at 128,276,151 bp
  • T to C, chromosome 8 at 71,478,958 bp
  • T to C, chromosome 8 at 105,017,841 bp
  • G to T, chromosome 8 at 105,566,835 bp
  • A to G, chromosome 8 at 106,010,682 bp
  • A to T, chromosome 9 at 37,383,893 bp
  • T to A, chromosome 9 at 37,631,606 bp
  • A to G, chromosome 9 at 38,061,500 bp
  • A to T, chromosome 9 at 67,759,801 bp
  • T to C, chromosome 9 at 79,672,997 bp
  • G to T, chromosome 9 at 85,844,376 bp
  • T to C, chromosome 10 at 39,065,619 bp
  • T to C, chromosome 10 at 78,043,480 bp
  • G to A, chromosome 11 at 20,826,491 bp
  • A to T, chromosome 11 at 32,422,203 bp
  • T to C, chromosome 11 at 55,228,324 bp
  • T to A, chromosome 11 at 55,256,647 bp
  • T to G, chromosome 11 at 69,364,697 bp
  • G to T, chromosome 11 at 70,096,832 bp
  • G to A, chromosome 11 at 73,295,383 bp
  • A to G, chromosome 11 at 87,085,768 bp
  • G to T, chromosome 11 at 98,435,335 bp
  • T to C, chromosome 12 at 31,334,746 bp
  • T to A, chromosome 12 at 84,576,270 bp
  • A to T, chromosome 13 at 12,454,943 bp
  • T to A, chromosome 13 at 76,062,410 bp
  • A to G, chromosome 13 at 100,780,926 bp
  • T to C, chromosome 14 at 36,896,313 bp
  • T to A, chromosome 14 at 36,896,314 bp
  • A to T, chromosome 14 at 70,439,475 bp
  • G to A, chromosome 15 at 11,241,462 bp
  • A to G, chromosome 15 at 66,931,081 bp
  • G to T, chromosome 15 at 102,298,529 bp
  • G to T, chromosome 16 at 20,333,588 bp
  • C to A, chromosome 16 at 56,822,338 bp
  • T to A, chromosome 17 at 23,308,061 bp
  • T to C, chromosome 17 at 34,572,615 bp
  • T to C, chromosome 17 at 34,593,977 bp
  • T to A, chromosome 17 at 38,275,106 bp
  • T to A, chromosome 17 at 46,255,695 bp
  • T to A, chromosome 17 at 50,606,798 bp
  • A to G, chromosome 17 at 54,277,153 bp
  • G to T, chromosome 17 at 57,236,217 bp
  • A to C, chromosome 17 at 72,603,421 bp
  • A to G, chromosome 18 at 4,334,766 bp
  • A to T, chromosome 18 at 24,770,493 bp
  • A to G, chromosome 18 at 35,656,849 bp
  • A to T, chromosome 18 at 69,955,991 bp
  • A to T, chromosome 18 at 77,381,972 bp
  • T to C, chromosome 18 at 80,211,946 bp
  • T to C, chromosome 19 at 3,977,572 bp
  • C to T, chromosome 19 at 10,027,381 bp
  • T to G, chromosome 19 at 41,256,229 bp
  • A to G, chromosome 19 at 57,714,702 bp
  • G to A, chromosome 19 at 60,766,798 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1748 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039780-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.