Strain Name:
C57BL/6J-MtgxR1799Btlr/Mmmh
Stock Number:
039829-MU
Citation ID:
RRID:MMRRC_039829-MU
Other Names:
R1799 (G1), C57BL/6J-MtgxR1799Btlr
Major Collection:

Gene Information

Gene Symbol: Slc1a3 [MGI:99917] (Mus musculus (mouse))
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Synonyms: B430115D02Rik, Eaat1, MGluT1, GLAST, Gmt1
Chromosome: 15
Alteration at locus: Chemically Induced
Gene Symbol: Fkbp2 [MGI:95542] (Mus musculus (mouse))
Name: FK506 binding protein 2
Synonyms: mFKBP13, 13kDa, mFKBP2
Chromosome: 19
Alteration at locus: Chemically Induced
Gene Symbol: Pcdh9 [MGI:1306801] (Mus musculus (mouse))
Name: protocadherin 9
Synonyms: C530050I23Rik, LOC382930, A730003J17Rik, C630029H24Rik, 1500001L12Rik
Chromosome: 14
Alteration at locus: Chemically Induced
Gene Symbol: Ubr5 [MGI:1918040] (Mus musculus (mouse))
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: Edd, 4432411E13Rik, Edd1
Chromosome: 15
Alteration at locus: Chemically Induced
Gene Symbol: Dnajc11 [MGI:2443386] (Mus musculus (mouse))
Name: DnaJ heat shock protein family (Hsp40) member C11
Synonyms: E030019A03Rik
Chromosome: 4
Alteration at locus: Chemically Induced
Gene Symbol: Lrp2 [MGI:95794] (Mus musculus (mouse))
Name: low density lipoprotein receptor-related protein 2
Synonyms: D230004K18Rik, Gp330, b2b1625.2Clo, Megalin
Chromosome: 2
Alteration at locus: Chemically Induced
Gene Symbol: Fbxo22 [MGI:1926014] (Mus musculus (mouse))
Name: F-box protein 22
Synonyms: 0610033L19Rik, 1600016C16Rik
Chromosome: 9
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 4,348,832 bp
  • A to T, chromosome 1 at 13,162,293 bp
  • C to T, chromosome 1 at 20,979,538 bp
  • T to A, chromosome 1 at 37,392,978 bp
  • A to G, chromosome 1 at 54,420,424 bp
  • T to C, chromosome 1 at 67,209,642 bp
  • G to T, chromosome 1 at 72,585,961 bp
  • T to A, chromosome 1 at 74,393,910 bp
  • T to A, chromosome 1 at 106,030,287 bp
  • T to C, chromosome 1 at 132,053,596 bp
  • A to T, chromosome 1 at 155,794,618 bp
  • A to G, chromosome 1 at 164,193,531 bp
  • A to G, chromosome 1 at 171,872,750 bp
  • A to T, chromosome 2 at 37,647,110 bp
  • A to G, chromosome 2 at 43,604,157 bp
  • G to T, chromosome 2 at 58,048,237 bp
  • T to A, chromosome 2 at 69,503,530 bp
  • A to G, chromosome 2 at 69,749,400 bp
  • A to C, chromosome 2 at 77,011,671 bp
  • T to C, chromosome 2 at 77,415,972 bp
  • T to C, chromosome 2 at 120,311,068 bp
  • T to C, chromosome 2 at 146,342,728 bp
  • A to G, chromosome 2 at 152,915,241 bp
  • A to T, chromosome 2 at 165,292,157 bp
  • A to G, chromosome 3 at 18,097,452 bp
  • T to A, chromosome 3 at 20,105,691 bp
  • A to G, chromosome 3 at 103,996,642 bp
  • T to C, chromosome 3 at 108,043,558 bp
  • C to G, chromosome 3 at 132,774,502 bp
  • C to T, chromosome 3 at 139,419,781 bp
  • G to A, chromosome 3 at 158,036,804 bp
  • A to G, chromosome 4 at 8,578,463 bp
  • A to T, chromosome 4 at 40,745,537 bp
  • T to G, chromosome 4 at 43,653,087 bp
  • T to C, chromosome 4 at 43,653,345 bp
  • A to T, chromosome 4 at 59,099,383 bp
  • T to A, chromosome 4 at 109,382,837 bp
  • A to G, chromosome 4 at 119,619,351 bp
  • G to A, chromosome 4 at 127,326,431 bp
  • C to T, chromosome 4 at 151,957,100 bp
  • A to G, chromosome 4 at 152,117,008 bp
  • A to G, chromosome 5 at 30,366,497 bp
  • A to G, chromosome 5 at 65,806,825 bp
  • G to A, chromosome 5 at 87,778,193 bp
  • A to C, chromosome 5 at 89,775,421 bp
  • A to G, chromosome 5 at 99,234,576 bp
  • C to A, chromosome 5 at 107,909,847 bp
  • T to A, chromosome 6 at 50,196,545 bp
  • T to A, chromosome 6 at 83,005,510 bp
  • T to C, chromosome 6 at 84,584,272 bp
  • T to C, chromosome 6 at 115,994,057 bp
  • T to C, chromosome 7 at 4,742,730 bp
  • A to T, chromosome 7 at 14,423,526 bp
  • T to G, chromosome 7 at 29,067,621 bp
  • T to A, chromosome 7 at 44,221,561 bp
  • T to A, chromosome 7 at 45,008,019 bp
  • T to A, chromosome 7 at 58,824,434 bp
  • A to G, chromosome 7 at 67,735,959 bp
  • G to T, chromosome 7 at 104,483,475 bp
  • T to A, chromosome 7 at 105,655,767 bp
  • A to T, chromosome 7 at 105,750,308 bp
  • A to T, chromosome 7 at 126,450,142 bp
  • A to T, chromosome 8 at 43,130,475 bp
  • A to T, chromosome 8 at 61,372,627 bp
  • A to G, chromosome 9 at 46,286,440 bp
  • T to C, chromosome 9 at 55,223,487 bp
  • A to T, chromosome 9 at 67,944,117 bp
  • A to G, chromosome 9 at 96,688,881 bp
  • A to G, chromosome 9 at 100,953,462 bp
  • G to A, chromosome 9 at 109,558,246 bp
  • T to A, chromosome 10 at 23,820,917 bp
  • G to A, chromosome 10 at 100,516,196 bp
  • G to T, chromosome 10 at 127,327,724 bp
  • A to G, chromosome 11 at 23,748,896 bp
  • A to T, chromosome 11 at 34,821,029 bp
  • A to G, chromosome 11 at 53,534,483 bp
  • C to A, chromosome 11 at 54,417,787 bp
  • A to G, chromosome 11 at 56,029,621 bp
  • G to A, chromosome 11 at 70,650,012 bp
  • T to A, chromosome 11 at 87,178,019 bp
  • C to T, chromosome 11 at 98,039,618 bp
  • T to A, chromosome 12 at 90,729,906 bp
  • T to C, chromosome 13 at 59,703,402 bp
  • C to T, chromosome 13 at 60,719,654 bp
  • A to C, chromosome 13 at 96,656,024 bp
  • T to A, chromosome 14 at 20,394,999 bp
  • T to C, chromosome 14 at 20,524,472 bp
  • G to T, chromosome 14 at 31,177,271 bp
  • T to A, chromosome 14 at 50,346,080 bp
  • T to C, chromosome 14 at 55,771,472 bp
  • A to T, chromosome 14 at 56,648,132 bp
  • G to T, chromosome 14 at 93,888,671 bp
  • G to T, chromosome 14 at 119,032,276 bp
  • A to G, chromosome 15 at 8,688,404 bp
  • T to C, chromosome 15 at 37,989,377 bp
  • A to C, chromosome 15 at 78,297,068 bp
  • G to A, chromosome 15 at 79,828,786 bp
  • G to T, chromosome 15 at 86,032,685 bp
  • G to A, chromosome 16 at 4,927,665 bp
  • A to G, chromosome 16 at 45,554,289 bp
  • T to A, chromosome 16 at 59,361,880 bp
  • G to T, chromosome 17 at 12,980,884 bp
  • T to C, chromosome 17 at 24,604,408 bp
  • A to G, chromosome 17 at 27,472,940 bp
  • G to A, chromosome 17 at 33,551,240 bp
  • A to T, chromosome 17 at 35,658,345 bp
  • A to T, chromosome 17 at 43,440,067 bp
  • C to T, chromosome 17 at 64,669,497 bp
  • T to C, chromosome 17 at 64,752,457 bp
  • T to C, chromosome 17 at 71,691,455 bp
  • G to A, chromosome 18 at 24,585,467 bp
  • A to C, chromosome 18 at 31,998,015 bp
  • A to T, chromosome 18 at 42,560,947 bp
  • C to A, chromosome 18 at 63,032,840 bp
  • T to C, chromosome 18 at 63,108,087 bp
  • A to G, chromosome 19 at 6,978,006 bp
  • T to A, chromosome 19 at 18,891,999 bp
  • T to C, chromosome X at 105,847,629 bp
Genotype Determination
ES Cell Line
N/A
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
MeSH Terms
    Strain Development
    C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
    Suggested Control Mice
    Wild-type littermates or C57BL/6J mice
    Donor
    Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
    Primary Reference
    MUTAGENETIX record for R1799 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

    Colony and Husbandry Information

    Colony Surveillance Program and Current Health Reports

    Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
    Coat Color
    Black
    MMRRC Breeding System
    Random intra-strain mating
    Breeding Scheme(s)
    When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
    Overall Breeding Performance
    Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
    Average litter size
    Undetermined
    Recommended wean age
    3 weeks

    Order Request Information

    Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

    Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

    Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

    The donor or their institution limits the distribution to non-profit institutions only.

    Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

    Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
    MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
    039829-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
    Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

    Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

    1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

    2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

    3 An aliquot contains a sufficient number of embryos (in one or more vials and based on the transfer success rate of the MMRRC facility) to transfer to at least two recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

    To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.