Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR1850Btlr/Mmmh
Stock Number:
039874-MU
Citation ID:
RRID:MMRRC_039874-MU
Other Names:
R1850 (G1), C57BL/6J-MtgxR1850Btlr
Major Collection:

Gene Information

Matr3
Name: matrin 3
Synonyms: 2810017I02Rik, 1110061A14Rik, D030046F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17184
HGNC: HGNC:6912
Homologene: 7830
Igf1
Name: insulin-like growth factor 1
Synonyms: C730016P09Rik, Igf-I, Igf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16000
HGNC: HGNC:5464
Homologene: 515
Bpifb3
Name: BPI fold containing family B, member 3
Synonyms: Rya3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 378700
Homologene: 18807
H2afy
Name: H2A histone family, member Y
Synonyms: mH2a1, H2AF12M, macroH2A1, MACROH2A1.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 26914
HGNC: HGNC:4740
Homologene: 3598
Scg3
Name: secretogranin III
Synonyms: 1B1075, Chgd, SgIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20255
VEGA: 9
Homologene: 7526
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, Alfy, 2610509D04Rik, Bchs, Ggtb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72145
Homologene: 22855
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: D730027C18Rik, 3110043H24Rik, 4930432B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75786
Homologene: 8844
Atf6
Name: activating transcription factor 6
Synonyms: ESTM49, 9130025P16Rik, Atf6alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226641
HGNC: HGNC:791
Homologene: 32015
Aff1
Name: AF4/FMR2 family, member 1
Synonyms: Mllt2h, Af4, 9630032B01Rik, Rob
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17355
HGNC: HGNC:7135
Homologene: 4340
Tcf12
Name: transcription factor 12
Synonyms: HEB, REB, HTF4, HEBAlt, ALF1, ME1, bHLHb20, HTF-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21406
Homologene: 40774
Sipa1l3
Name: signal-induced proliferation-associated 1 like 3
Synonyms: 2610511M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74206
Homologene: 77938
Dusp12
Name: dual specificity phosphatase 12
Synonyms: ESTM36, mVH1, VH1, LMW-DSP4, T-DSP4, 1190004O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 80915
HGNC: HGNC:3067
Homologene: 5238
Smchd1
Name: SMC hinge domain containing 1
Synonyms: MommeD1, 4931400A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74355
Homologene: 23665
Chd4
Name: chromodomain helicase DNA binding protein 4
Synonyms: D6Ertd380e, 9530019N15Rik, Mi-2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 107932
HGNC: HGNC:1919
Homologene: 68175
Pparg
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, Ppar-gamma2, PPAR-gamma, PPARgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19016
HGNC: HGNC:9236
Homologene: 7899
Jcad
Name: junctional cadherin 5 associated
Synonyms: 9430020K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240185
VEGA: 18
Homologene: 19370
Lepr
Name: leptin receptor
Synonyms: Leprb, LEPROT, Modb1, OB-RGRP, leptin receptor gene-related protein, obl, obese-like, Obr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16847
HGNC: HGNC:6554
Homologene: 1731
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 2310042E16Rik, Coh1, 1810042B05Rik, C330002D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: Supt6h, 5131400N11Rik, SPT6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20926
Homologene: 40661
Plec
Name: plectin
Synonyms: Plec1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18810
HGNC: HGNC:9069
Homologene: 384
Nrip1
Name: nuclear receptor interacting protein 1
Synonyms: RIP140, 8430438I05Rik, 6030458L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268903
HGNC: HGNC:8001
Homologene: 2606
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Lrch3
Name: leucine-rich repeats and calponin homology (CH) domain containing 3
Synonyms: 2210409B11Rik, LOC385628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70144
Homologene: 13111
Camk1d
Name: calcium/calmodulin-dependent protein kinase ID
Synonyms: CaMKIdelta, CKLiK, A630059D12Rik, E030025C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227541
Homologene: 121858
Emc1
Name: ER membrane protein complex subunit 1
Synonyms: C230096C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230866
Homologene: 9002
Rnf214
Name: ring finger protein 214
Synonyms: D130054N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235315
Homologene: 109357
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, Hapip, E530005C20Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Sept5
Name: septin 5
Synonyms: Cdcrel1, Pnutl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 18951
VEGA: 16
HGNC: HGNC:9164
Homologene: 74446
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 328783
VEGA: 17
HGNC: null
Homologene: 18633
Myo6
Name: myosin VI
Synonyms: rsv, Tlc, Myo6rsv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17920
HGNC: HGNC:7605
Homologene: 56417
Txndc11
Name: thioredoxin domain containing 11
Synonyms: Txdc11, 2810408E11Rik, EFP1, EF-hand binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 106200
Homologene: 9301
Tesk1
Name: testis specific protein kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21754
Homologene: 4577
Echdc1
Name: enoyl Coenzyme A hydratase domain containing 1
Synonyms: 1700028A24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52665
Homologene: 23106
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Fbn2
Name: fibrillin 2
Synonyms: Sne, Fib-2, sy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Lmntd1
Name: lamin tail domain containing 1
Synonyms: Ifltd1, 4933403M22Rik, Lmna-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74071
Homologene: 69453
Myo1h
Name: myosin 1H
Synonyms: 4631401O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231646
Homologene: 82639
Crybg1
Name: crystallin beta-gamma domain containing 1
Synonyms: Aim1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11630
HGNC: HGNC:356
Homologene: 18168
Pcdh18
Name: protocadherin 18
Synonyms: PCDH68L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 73173
Homologene: 10389
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: B230399N07Rik, 4930532L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269610
Homologene: 56712
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215772
Homologene: 100289
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 628870
Homologene: 46008
Olfr741
Name: olfactory receptor 741
Synonyms: GA_x6K02T2PMLR-6197851-6198786, MOR106-10, MOR106-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258233
HGNC: null
Homologene: null
Slc9a3
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms: NHE3, NHE-3, 9030624O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105243
VEGA: 13
Homologene: 55804
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: 1600012D06Rik, Abp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 2310021P13Rik, 4832404P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268721
VEGA: 14
Homologene: 34313
Cfap57
Name: cilia and flagella associated protein 57
Synonyms: LOC384050, C130004B06Rik, 1110020C03Rik, Wdr65
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68625
Homologene: 51350
Slc27a1
Name: solute carrier family 27 (fatty acid transporter), member 1
Synonyms: Fatp, FATP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 26457
Homologene: 8063
Prl2c5
Name: prolactin family 2, subfamily c, member 5
Synonyms: Mrpplf4, MRP-4, PLF-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 107849
HGNC: null
Homologene: 40763
Adam28
Name: a disintegrin and metallopeptidase domain 28
Synonyms: C130072N01Rik, Dtgn1, D430033C21Rik, MDC-L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 13522
VEGA: 14
HGNC: HGNC:206
Homologene: 40705
Pex5l
Name: peroxisomal biogenesis factor 5-like
Synonyms: Pex2, 1700016J08Rik, PXR2, TRIP8b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 58869
Homologene: 9562
Vmn2r120
Name: vomeronasal 2, receptor 120
Synonyms: EG224916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224916
HGNC: null
Homologene: null
Col17a1
Name: collagen, type XVII, alpha 1
Synonyms: Bpag, BPAg2, Bpag2, BP180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12821
HGNC: HGNC:2194
Homologene: 7276
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: STEF, 3000002F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 24001
VEGA: 17
Homologene: 40796
Vmn1r201
Name: vomeronasal 1 receptor 201
Synonyms: V1ri4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 171255
HGNC: null
Homologene: 110880
Pbx3
Name: pre B cell leukemia homeobox 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18516
HGNC: HGNC:8634
Homologene: 21243
Sult1b1
Name: sulfotransferase family 1B, member 1
Synonyms: Dopa/tyrosine sulfotransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56362
Homologene: 69169
S1pr5
Name: sphingosine-1-phosphate receptor 5
Synonyms: S1P5, lpB4, Edg8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 94226
Homologene: 11031
Mtif2
Name: mitochondrial translational initiation factor 2
Synonyms: IF-2mt, 2310038D14Rik, 2410112O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76784
HGNC: HGNC:7441
Homologene: 1840
Serpinb7
Name: serine (or cysteine) peptidase inhibitor, clade B, member 7
Synonyms: ovalbumin, 4631416M05Rik, megsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 116872
Homologene: 68363
Olfr1082
Name: olfactory receptor 1082
Synonyms: GA_x6K02T2Q125-48079993-48079157, MOR192-4_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 404473
HGNC: null
Homologene: 104285
Rcor3
Name: REST corepressor 3
Synonyms: E130101E15Rik, C730034D20Rik, 4921514E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 214742
Homologene: 135671
Olfr1415
Name: olfactory receptor 1415
Synonyms: MOR103-12, GA_x6K02T2R7CC-81266841-81267776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258228
Homologene: 79367
Psph
Name: phosphoserine phosphatase
Synonyms: PSPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100678
HGNC: HGNC:9577
Homologene: 31245
Gabra1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
Synonyms: GABAAR alpha1, GABAA alpha 1, Gabra-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14394
HGNC: HGNC:4075
Homologene: 629
Ces1a
Name: carboxylesterase 1A
Synonyms: Gm4976
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244595
HGNC: HGNC:1863
Homologene: 134142
Slco5a1
Name: solute carrier organic anion transporter family, member 5A1
Synonyms: A630033C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240726
Homologene: 57135
4430402I18Rik
Name: RIKEN cDNA 4430402I18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 381218
Homologene: 128454
Insyn1
Name: inhibitory synaptic factor 1
Synonyms: 6030419C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319477
VEGA: 9
Homologene: 18538
Slc2a10
Name: solute carrier family 2 (facilitated glucose transporter), member 10
Synonyms: Glut10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 170441
Homologene: 38551
Tspan8
Name: tetraspanin 8
Synonyms: Tm4sf3, E330007O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216350
VEGA: 10
Homologene: 20968
Runx3
Name: runt related transcription factor 3
Synonyms: Cbfa3, AML2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12399
Homologene: 37914
Trdv2-2
Name: T cell receptor delta variable 2-2
Synonyms: Gm17015
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 320913
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 12,881,284 bp
  • T to A, chromosome 1 at 92,491,402 bp
  • T to C, chromosome 1 at 107,428,295 bp
  • A to T, chromosome 1 at 170,819,286 bp
  • G to A, chromosome 1 at 170,880,629 bp
  • T to A, chromosome 1 at 192,120,111 bp
  • T to C, chromosome 2 at 5,362,015 bp
  • A to T, chromosome 2 at 34,176,820 bp
  • T to A, chromosome 2 at 82,984,589 bp
  • A to T, chromosome 2 at 86,594,104 bp
  • G to A, chromosome 2 at 91,595,713 bp
  • C to G, chromosome 2 at 153,929,344 bp
  • C to A, chromosome 2 at 165,515,213 bp
  • A to T, chromosome 3 at 32,950,876 bp
  • T to C, chromosome 3 at 49,756,405 bp
  • C to T, chromosome 4 at 43,443,576 bp
  • C to A, chromosome 4 at 101,733,423 bp
  • G to A, chromosome 4 at 118,599,894 bp
  • G to A, chromosome 4 at 135,163,348 bp
  • A to T, chromosome 4 at 139,359,373 bp
  • T to C, chromosome 4 at 152,370,533 bp
  • A to G, chromosome 5 at 87,520,841 bp
  • A to G, chromosome 5 at 101,894,999 bp
  • G to T, chromosome 5 at 103,833,907 bp
  • A to T, chromosome 5 at 114,329,257 bp
  • A to T, chromosome 5 at 129,766,576 bp
  • C to T, chromosome 6 at 48,905,268 bp
  • T to A, chromosome 6 at 115,450,980 bp
  • T to A, chromosome 6 at 125,121,656 bp
  • T to A, chromosome 6 at 145,413,480 bp
  • A to T, chromosome 7 at 29,339,126 bp
  • T to C, chromosome 8 at 71,580,703 bp
  • T to A, chromosome 8 at 93,027,326 bp
  • T to C, chromosome 9 at 7,001,448 bp
  • A to T, chromosome 9 at 21,244,129 bp
  • A to T, chromosome 9 at 45,869,448 bp
  • A to T, chromosome 9 at 58,499,109 bp
  • C to A, chromosome 9 at 71,868,215 bp
  • C to T, chromosome 9 at 75,682,167 bp
  • T to A, chromosome 9 at 80,307,658 bp
  • C to A, chromosome 10 at 10,442,502 bp
  • A to T, chromosome 10 at 29,344,603 bp
  • A to G, chromosome 10 at 43,997,674 bp
  • A to C, chromosome 10 at 87,861,374 bp
  • T to A, chromosome 10 at 107,878,064 bp
  • C to T, chromosome 10 at 115,833,225 bp
  • A to G, chromosome 11 at 29,540,683 bp
  • T to A, chromosome 11 at 42,179,576 bp
  • A to G, chromosome 11 at 78,219,877 bp
  • A to G, chromosome 13 at 13,185,792 bp
  • A to G, chromosome 13 at 22,474,631 bp
  • T to C, chromosome 13 at 56,096,239 bp
  • A to G, chromosome 13 at 74,161,770 bp
  • C to T, chromosome 14 at 20,710,747 bp
  • G to A, chromosome 14 at 50,485,598 bp
  • A to T, chromosome 14 at 53,961,300 bp
  • T to A, chromosome 14 at 68,639,195 bp
  • A to T, chromosome 15 at 35,674,959 bp
  • T to C, chromosome 15 at 76,188,232 bp
  • T to C, chromosome 16 at 11,088,404 bp
  • A to T, chromosome 16 at 18,625,210 bp
  • A to G, chromosome 16 at 32,986,793 bp
  • A to T, chromosome 16 at 33,975,923 bp
  • T to C, chromosome 16 at 76,293,344 bp
  • A to G, chromosome 17 at 3,437,235 bp
  • G to A, chromosome 17 at 25,742,934 bp
  • T to A, chromosome 17 at 57,525,826 bp
  • T to C, chromosome 17 at 71,389,771 bp
  • C to A, chromosome 18 at 4,675,730 bp
  • A to G, chromosome 18 at 35,582,057 bp
  • C to A, chromosome 18 at 58,039,305 bp
  • T to C, chromosome 19 at 28,939,171 bp
  • A to T, chromosome 19 at 47,653,421 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1850 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039874-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.