Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR1880Btlr/Mmmh
Stock Number:
039901-MU
Citation ID:
RRID:MMRRC_039901-MU
Other Names:
R1880 (G1), C57BL/6J-MtgxR1880Btlr
Major Collection:

Gene Information

Col1a1
Name: collagen, type I, alpha 1
Synonyms: Mov-13, Cola1, Col1a-1, Cola-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12842
HGNC: HGNC:2197
Homologene: 73874
Sema3c
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Synonyms: 1110036B02Rik, Semae
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20348
Homologene: 36201
Snap25
Name: synaptosomal-associated protein 25
Synonyms: SNAP-25, sp, GENA 70, Bdr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20614
Homologene: 13311
Mmp10
Name: matrix metallopeptidase 10
Synonyms: stromelysin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17384
VEGA: 9
HGNC: HGNC:7156
Homologene: 20546
Frrs1
Name: ferric-chelate reductase 1
Synonyms: Sdfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20321
Homologene: 40653
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Med1
Name: mediator complex subunit 1
Synonyms: CRSP210, Pparbp, TRAP220, DRIP205, PBP, l11Jus15, TRAP 220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19014
HGNC: HGNC:9234
Homologene: 21002
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18193
VEGA: 13
Homologene: 32543
Gtf2h3
Name: general transcription factor IIH, polypeptide 3
Synonyms: BTF2, D5Ertd679e, 5033417D07Rik, 34kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 209357
HGNC: HGNC:4657
Homologene: 1160
Zfp13
Name: zinc finger protein 13
Synonyms: Krox-8, Zfp-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22654
VEGA: 17
Homologene: 2580
Sema4b
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Synonyms: Semac, SemC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20352
Homologene: 8426
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, Alfy, 2610509D04Rik, Bchs, Ggtb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72145
Homologene: 22855
Cltc
Name: clathrin, heavy polypeptide (Hc)
Synonyms: CHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67300
HGNC: HGNC:2092
Homologene: 3572
Usp38
Name: ubiquitin specific peptidase 38
Synonyms: 4631402N15Rik, 4833420O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74841
Homologene: 12367
Patj
Name: PATJ, crumbs cell polarity complex component
Synonyms: Cipp, Inadl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12695
Homologene: 72199
Snrnp70
Name: small nuclear ribonucleoprotein 70 (U1)
Synonyms: Snrp70, 2700022N21Rik, Srnp70, U1-70, 3200002N22Rik, Rnulp70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20637
Homologene: 20672
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Hnrnpul1
Name: heterogeneous nuclear ribonucleoprotein U-like 1
Synonyms: E130317O14Rik, Hnrpul1, E1B-AP5, E1BAP5, Hnrnpul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232989
Homologene: 31419
Afdn
Name: afadin, adherens junction formation factor
Synonyms: AF6, S-afadin, Mllt4, I-afadin, 5033403D15Rik, Afadin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: peroxisome biogenesis factor 1, 5430414H02Rik, E330005K07Rik, ZWS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Map3k12
Name: mitogen-activated protein kinase kinase kinase 12
Synonyms: Zpk, MUK, DLK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 26404
HGNC: HGNC:6851
Homologene: 4592
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VRL-2, Trp12, VROAC, OTRPC4, VR-OAC, 0610033B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 63873
Homologene: 11003
Eva1c
Name: eva-1 homolog C (C. elegans)
Synonyms: Fam176c, 4931408A02Rik, 1700092M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70967
Homologene: 14383
Rpf2
Name: ribosome production factor 2 homolog
Synonyms: 2810470K21Rik, Bxdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67239
Homologene: 6404
Pomt2
Name: protein-O-mannosyltransferase 2
Synonyms: A830009D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217734
VEGA: 12
Homologene: 5297
Kel
Name: Kell blood group
Synonyms: CD238
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23925
HGNC: HGNC:6308
Homologene: 362
Gata4
Name: GATA binding protein 4
Synonyms: Gata-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 14463
HGNC: HGNC:4173
Homologene: 1551
Ell3
Name: elongation factor RNA polymerase II-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269344
Homologene: 11859
Ctnnd2
Name: catenin (cadherin associated protein), delta 2
Synonyms: Catnd2, Nprap, neurojugin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18163
VEGA: 15
HGNC: HGNC:2516
Homologene: 55574
Zkscan17
Name: zinc finger with KRAB and SCAN domains 17
Synonyms: Zfp496, Nizp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268417
Homologene: 13108
Itga11
Name: integrin alpha 11
Synonyms: 4732459H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319480
HGNC: HGNC:6136
Homologene: 8151
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Dpysl3
Name: dihydropyrimidinase-like 3
Synonyms: Ulip1, TUC4, CRMP-4, Ulip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 22240
HGNC: HGNC:3015
Homologene: 20361
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, fibrocystin L, D86 mRNA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 192190
Homologene: 16332
Eaf2
Name: ELL associated factor 2
Synonyms: Festa, U19, FESTA-S, FESTA-L, Traits
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 106389
Homologene: 10208
Polq
Name: polymerase (DNA directed), theta
Synonyms: A430110D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 77782
HGNC: HGNC:9186
Homologene: 32727
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Plpp4
Name: phospholipid phosphatase 4
Synonyms: Ppapdc1a, LOC381925, C030048B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381925
Homologene: 38751
9930021J03Rik
Name: RIKEN cDNA 9930021J03 gene
Synonyms: Gm9832
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240613
Homologene: 19046
Tbc1d17
Name: TBC1 domain family, member 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233204
Homologene: 11656
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Arhgef5
Name: Rho guanine nucleotide exchange factor (GEF) 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 54324
Homologene: 66300
Atp10b
Name: ATPase, class V, type 10B
Synonyms: 9030605H24Rik, 5930426O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 319767
Homologene: 70969
Capn2
Name: calpain 2
Synonyms: m-calpain, Capa-2, Capa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12334
HGNC: HGNC:1479
Homologene: 1326
Megf8
Name: multiple EGF-like-domains 8
Synonyms: Egfl4, b2b1702Clo, m687Ddg, b2b288Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269878
HGNC: HGNC:3233
Homologene: 15988
Ppp4r4
Name: protein phosphatase 4, regulatory subunit 4
Synonyms: 8430415E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74521
Homologene: 12571
Axl
Name: AXL receptor tyrosine kinase
Synonyms: Ufo, Ark, Tyro7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 26362
HGNC: HGNC:905
Homologene: 7583
Fbxo43
Name: F-box protein 43
Synonyms: XErp1 homolog, 4930533G20Rik, early mitotic inhibitor 2, Emi2, endogenous meiotic inhibitor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 78803
VEGA: 15
Homologene: 66393
Olfr513
Name: olfactory receptor 513
Synonyms: GA_x6K02T2PBJ9-11084889-11085818, MOR195-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258718
HGNC: null
Homologene: 64908
Zfp759
Name: zinc finger protein 759
Synonyms: Rslcan-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 268670
VEGA: 13
HGNC: null
Homologene: null
Vps36
Name: vacuolar protein sorting 36
Synonyms: 2210415M20Rik, 1700010A24Rik, Eap45, 2810408E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 70160
Homologene: 9374
Gm15448
Name: predicted gene 15448
Synonyms: ENSMUSG00000074419
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100041146
HGNC: HGNC:6607
Homologene: 134028
Tas2r144
Name: taste receptor, type 2, member 144
Synonyms: Tas2r44, mt2r33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387515
Homologene: 47977
Lgr5
Name: leucine rich repeat containing G protein coupled receptor 5
Synonyms: Gpr49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14160
HGNC: HGNC:4504
Homologene: 20807
Gm7736
Name: predicted gene 7736
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 665662
HGNC: null
Homologene: null
Habp2
Name: hyaluronic acid binding protein 2
Synonyms: FSAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226243
HGNC: HGNC:4798
Homologene: 3050
Olfr1137
Name: olfactory receptor 1137
Synonyms: MOR177-20, MOR40-9P, GA_x6K02T2Q125-49215724-49214792
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258101
HGNC: null
Homologene: 79380
Gmnc
Name: geminin coiled-coil domain containing
Synonyms: LOC385639, Gm606, LOC239789
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239789
VEGA: 16
Homologene: 79940
Cd209f
Name: CD209f antigen
Synonyms: 1810029C22Rik, SIGNR8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 69142
HGNC: null
Homologene: 114519
Dus4l
Name: dihydrouridine synthase 4-like (S. cerevisiae)
Synonyms: 2310069P03Rik, 2700089B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 71916
VEGA: 12
Homologene: 6535
Erg
Name: ETS transcription factor
Synonyms: D030036I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 13876
HGNC: HGNC:3446
Homologene: 15848
Hspa2
Name: heat shock protein 2
Synonyms: 70kDa, Hsp70-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 15512
VEGA: 12
HGNC: HGNC:5235
Homologene: 68564
Btnl2
Name: butyrophilin-like 2
Synonyms: butyrophylin-like MHC class II associated, BTL-II, BTLN2, NG9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 547431
HGNC: HGNC:1142
Homologene: 10482
Olfr807
Name: olfactory receptor 807
Synonyms: MOR117-1, GA_x6K02T2PULF-11434134-11433199
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258931
HGNC: null
Homologene: 27300
AC147806.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Lpxn
Name: leupaxin
Synonyms: A530083L21Rik, 4933402K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107321
VEGA: 19
Homologene: 3536
Vmn1r192
Name: vomeronasal 1 receptor 192
Synonyms: V1ri1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 252907
HGNC: null
Homologene: 110880
Vmn1r91
Name: vomeronasal 1 receptor 91
Synonyms: Gm8442
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 667067
HGNC: null
Homologene: 104166
Olfr263
Name: olfactory receptor 263
Synonyms: MOR256-61, MOR256-31, IA3, Olfr42, GA_x6K02T2N5E5-9379-8514, Olfr263-ps1, MOR256-37P, GA_x6K02T2QHY8-12114828-12113875
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18341
HGNC: HGNC:8281
Homologene: 12791
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • CAGAGAGA to CAGAGAGAGA, chromosome 1 at 85,577,224 bp
  • C to T, chromosome 1 at 150,638,900 bp
  • A to G, chromosome 1 at 182,489,016 bp
  • C to A, chromosome 2 at 52,258,731 bp
  • C to A, chromosome 2 at 87,711,295 bp
  • T to C, chromosome 2 at 121,440,311 bp
  • G to A, chromosome 2 at 136,777,385 bp
  • T to C, chromosome 3 at 116,896,795 bp
  • C to T, chromosome 4 at 98,497,240 bp
  • G to A, chromosome 4 at 123,438,591 bp
  • T to C, chromosome 5 at 3,605,770 bp
  • A to T, chromosome 5 at 17,727,466 bp
  • T to C, chromosome 5 at 101,917,435 bp
  • C to T, chromosome 5 at 114,623,626 bp
  • C to T, chromosome 5 at 124,584,273 bp
  • G to A, chromosome 6 at 41,687,545 bp
  • C to T, chromosome 6 at 42,216,070 bp
  • C to A, chromosome 6 at 43,273,088 bp
  • C to T, chromosome 7 at 3,824,951 bp
  • A to T, chromosome 7 at 20,101,773 bp
  • G to A, chromosome 7 at 25,334,860 bp
  • A to G, chromosome 7 at 25,733,098 bp
  • T to C, chromosome 7 at 25,774,548 bp
  • A to G, chromosome 7 at 44,844,404 bp
  • T to C, chromosome 7 at 45,377,362 bp
  • A to T, chromosome 7 at 80,216,792 bp
  • T to C, chromosome 7 at 108,755,128 bp
  • A to C, chromosome 7 at 129,316,366 bp
  • A to G, chromosome 8 at 4,105,464 bp
  • T to C, chromosome 8 at 22,213,562 bp
  • T to C, chromosome 8 at 81,001,066 bp
  • T to C, chromosome 9 at 7,505,574 bp
  • A to G, chromosome 9 at 62,677,949 bp
  • T to C, chromosome 9 at 95,947,246 bp
  • T to C, chromosome 10 at 40,233,158 bp
  • T to C, chromosome 10 at 115,452,279 bp
  • A to G, chromosome 10 at 129,755,421 bp
  • G to T, chromosome 11 at 43,259,432 bp
  • G to A, chromosome 11 at 59,487,629 bp
  • A to G, chromosome 11 at 86,712,631 bp
  • A to G, chromosome 11 at 94,950,568 bp
  • A to T, chromosome 11 at 98,180,250 bp
  • T to C, chromosome 12 at 31,640,870 bp
  • G to A, chromosome 12 at 76,405,920 bp
  • G to T, chromosome 12 at 84,829,271 bp
  • G to T, chromosome 12 at 87,135,596 bp
  • T to A, chromosome 12 at 103,605,035 bp
  • A to T, chromosome 13 at 21,133,632 bp
  • G to T, chromosome 13 at 22,187,594 bp
  • T to A, chromosome 13 at 55,213,793 bp
  • T to C, chromosome 13 at 67,139,212 bp
  • G to T, chromosome 14 at 63,204,695 bp
  • A to G, chromosome 15 at 31,005,081 bp
  • T to C, chromosome 15 at 36,162,515 bp
  • C to T, chromosome 15 at 44,457,632 bp
  • A to T, chromosome 15 at 44,525,242 bp
  • A to G, chromosome 15 at 102,502,064 bp
  • T to C, chromosome 16 at 26,965,611 bp
  • A to T, chromosome 16 at 36,800,579 bp
  • T to C, chromosome 16 at 37,086,592 bp
  • T to C, chromosome 16 at 90,897,415 bp
  • G to A, chromosome 16 at 95,377,309 bp
  • A to G, chromosome 17 at 13,852,353 bp
  • T to A, chromosome 17 at 21,153,144 bp
  • A to T, chromosome 17 at 23,580,238 bp
  • A to G, chromosome 17 at 34,365,363 bp
  • A to T, chromosome 18 at 43,329,874 bp
  • A to G, chromosome 19 at 12,804,088 bp
  • C to A, chromosome 19 at 29,718,123 bp
  • A to G, chromosome 19 at 56,317,828 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1880 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039901-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.