Strain Name:
C57BL/6J-MtgxR1907Btlr/Mmmh
Stock Number:
039926-MU
Citation ID:
RRID:MMRRC_039926-MU
Other Names:
R1907 (G1), C57BL/6J-MtgxR1907Btlr
Major Collection:

Gene Information

Gene Symbol: Pcp2 [MGI:97508] (Mus musculus (mouse))
Name: Purkinje cell protein 2 (L7)
Synonyms: L7, Pcp-2
Chromosome: 8
Alteration at locus: Chemically Induced
Gene Symbol: Drd1 [MGI:99578] (Mus musculus (mouse))
Name: dopamine receptor D1
Synonyms: D1 receptor, Drd-1, Drd1a, Gpcr15, C030036C15Rik
Chromosome: 13
Alteration at locus: Chemically Induced
Gene Symbol: Macf1 [MGI:108559] (Mus musculus (mouse))
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Chromosome: 4
Alteration at locus: Chemically Induced
Gene Symbol: Dscaml1 [MGI:2150309] (Mus musculus (mouse))
Name: DS cell adhesion molecule like 1
Synonyms: 4921507G06Rik, 4930435C18Rik
Chromosome: 9
Alteration at locus: Chemically Induced
Gene Symbol: Eif4g3 [MGI:1923935] (Mus musculus (mouse))
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: G1-419-52, 4930523M17Rik, repro8, eIF4GII, 1500002J22Rik
Chromosome: 4
Alteration at locus: Chemically Induced
Gene Symbol: Psme4 [MGI:2143994] (Mus musculus (mouse))
Name: proteasome (prosome, macropain) activator subunit 4
Chromosome: 11
Alteration at locus: Chemically Induced
Gene Symbol: Hnrnpll [MGI:1919942] (Mus musculus (mouse))
Name: heterogeneous nuclear ribonucleoprotein L-like
Synonyms: Hnrpll, 2810036L13Rik, 2510028H02Rik
Chromosome: 17
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 52,789,670 bp
  • C to T, chromosome 1 at 96,842,499 bp
  • G to A, chromosome 1 at 97,775,447 bp
  • T to C, chromosome 1 at 105,638,215 bp
  • A to T, chromosome 1 at 131,769,191 bp
  • T to C, chromosome 1 at 136,260,800 bp
  • T to A, chromosome 1 at 160,645,310 bp
  • A to G, chromosome 1 at 171,504,270 bp
  • A to T, chromosome 1 at 172,072,143 bp
  • C to T, chromosome 1 at 188,715,064 bp
  • A to G, chromosome 1 at 192,901,835 bp
  • A to G, chromosome 2 at 67,516,356 bp
  • C to T, chromosome 2 at 70,579,138 bp
  • T to C, chromosome 2 at 72,411,916 bp
  • T to C, chromosome 2 at 76,870,856 bp
  • T to A, chromosome 2 at 79,868,307 bp
  • C to T, chromosome 2 at 82,983,428 bp
  • T to C, chromosome 2 at 86,236,110 bp
  • T to A, chromosome 2 at 103,087,175 bp
  • G to T, chromosome 2 at 120,713,812 bp
  • A to G, chromosome 2 at 126,586,342 bp
  • A to T, chromosome 2 at 178,069,891 bp
  • A to G, chromosome 3 at 30,598,567 bp
  • G to C, chromosome 3 at 38,454,052 bp
  • T to C, chromosome 3 at 85,672,633 bp
  • C to T, chromosome 3 at 89,946,276 bp
  • A to T, chromosome 3 at 106,405,950 bp
  • T to C, chromosome 3 at 108,041,277 bp
  • A to T, chromosome 3 at 119,761,749 bp
  • C to A, chromosome 3 at 122,069,012 bp
  • A to C, chromosome 4 at 108,255,226 bp
  • A to T, chromosome 4 at 123,372,399 bp
  • C to T, chromosome 4 at 138,158,415 bp
  • T to A, chromosome 4 at 143,895,491 bp
  • T to C, chromosome 4 at 155,078,499 bp
  • A to G, chromosome 5 at 14,678,511 bp
  • A to G, chromosome 5 at 22,044,962 bp
  • T to C, chromosome 5 at 31,466,582 bp
  • A to G, chromosome 5 at 86,830,630 bp
  • T to A, chromosome 5 at 87,139,630 bp
  • C to T, chromosome 5 at 88,504,622 bp
  • A to G, chromosome 5 at 103,580,709 bp
  • T to A, chromosome 5 at 104,486,806 bp
  • G to T, chromosome 5 at 144,175,110 bp
  • A to G, chromosome 5 at 149,552,426 bp
  • G to T, chromosome 6 at 29,497,835 bp
  • T to A, chromosome 6 at 67,295,286 bp
  • T to A, chromosome 6 at 120,761,160 bp
  • T to A, chromosome 6 at 124,909,487 bp
  • T to C, chromosome 6 at 131,659,988 bp
  • A to C, chromosome 6 at 139,844,042 bp
  • T to A, chromosome 6 at 141,736,092 bp
  • C to T, chromosome 6 at 149,041,576 bp
  • A to G, chromosome 7 at 17,752,384 bp
  • A to G, chromosome 7 at 29,339,167 bp
  • A to G, chromosome 7 at 35,449,854 bp
  • C to T, chromosome 7 at 45,708,320 bp
  • G to T, chromosome 7 at 46,014,169 bp
  • T to A, chromosome 7 at 103,731,983 bp
  • G to A, chromosome 7 at 104,917,065 bp
  • T to A, chromosome 7 at 108,868,498 bp
  • G to A, chromosome 8 at 3,624,904 bp
  • T to A, chromosome 8 at 9,988,170 bp
  • G to A, chromosome 8 at 84,916,266 bp
  • A to T, chromosome 8 at 110,893,378 bp
  • T to C, chromosome 8 at 111,011,474 bp
  • T to C, chromosome 8 at 119,749,876 bp
  • T to C, chromosome 9 at 18,988,441 bp
  • T to A, chromosome 9 at 30,433,576 bp
  • T to G, chromosome 9 at 37,746,433 bp
  • G to A, chromosome 9 at 45,740,480 bp
  • A to C, chromosome 9 at 78,064,773 bp
  • G to A, chromosome 9 at 108,053,636 bp
  • T to A, chromosome 10 at 26,271,856 bp
  • T to G, chromosome 10 at 39,072,758 bp
  • T to C, chromosome 10 at 79,874,069 bp
  • T to C, chromosome 10 at 81,154,363 bp
  • G to A, chromosome 10 at 117,215,731 bp
  • G to A, chromosome 10 at 121,090,097 bp
  • T to A, chromosome 11 at 6,602,540 bp
  • T to C, chromosome 11 at 30,810,922 bp
  • T to C, chromosome 11 at 43,596,167 bp
  • T to G, chromosome 11 at 60,932,229 bp
  • T to C, chromosome 11 at 69,394,740 bp
  • T to A, chromosome 11 at 70,544,184 bp
  • T to A, chromosome 11 at 78,191,255 bp
  • T to A, chromosome 11 at 85,914,523 bp
  • C to A, chromosome 11 at 103,457,156 bp
  • T to G, chromosome 11 at 105,126,840 bp
  • C to T, chromosome 11 at 113,838,646 bp
  • A to G, chromosome 11 at 119,331,259 bp
  • G to T, chromosome 12 at 69,296,960 bp
  • G to A, chromosome 12 at 118,127,556 bp
  • G to A, chromosome 13 at 12,225,532 bp
  • A to G, chromosome 13 at 20,910,094 bp
  • G to A, chromosome 13 at 47,064,120 bp
  • A to T, chromosome 13 at 54,053,252 bp
  • A to G, chromosome 13 at 65,035,876 bp
  • A to G, chromosome 13 at 81,592,551 bp
  • A to T, chromosome 13 at 85,226,572 bp
  • T to C, chromosome 14 at 88,468,704 bp
  • T to A, chromosome 15 at 30,806,909 bp
  • T to C, chromosome 15 at 75,711,824 bp
  • C to T, chromosome 15 at 76,372,893 bp
  • T to C, chromosome 15 at 80,153,668 bp
  • T to C, chromosome 15 at 80,375,264 bp
  • T to A, chromosome 15 at 101,573,366 bp
  • T to A, chromosome 16 at 44,357,830 bp
  • G to A, chromosome 17 at 69,387,390 bp
  • C to A, chromosome 17 at 78,942,117 bp
  • A to G, chromosome 17 at 80,035,329 bp
  • A to T, chromosome 18 at 31,976,999 bp
  • A to T, chromosome 18 at 37,996,671 bp
  • T to A, chromosome 18 at 43,438,128 bp
Genotype Determination
ES Cell Line
N/A
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
MeSH Terms
    Strain Development
    C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
    Suggested Control Mice
    Wild-type littermates or C57BL/6J mice
    Donor
    Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
    Primary Reference
    MUTAGENETIX record for R1907 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

    Colony and Husbandry Information

    Colony Surveillance Program and Current Health Reports

    Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
    Coat Color
    Black
    MMRRC Breeding System
    Random intra-strain mating
    Breeding Scheme(s)
    When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
    Overall Breeding Performance
    Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
    Average litter size
    Undetermined
    Recommended wean age
    3 weeks

    Order Request Information

    Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

    Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

    Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

    The donor or their institution limits the distribution to non-profit institutions only.

    Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

    Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
    MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
    039926-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
    Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

    Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

    1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

    2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

    3 An aliquot contains a sufficient number of embryos (in one or more vials and based on the transfer success rate of the MMRRC facility) to transfer to at least two recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

    To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.