Strain Name:
C57BL/6J-MtgxR1975Btlr/Mmmh
Stock Number:
039988-MU
Citation ID:
RRID:MMRRC_039988-MU
Other Names:
R1975 (G1), C57BL/6J-MtgxR1975Btlr
Major Collection:

Gene Information

Chrnb4
Name: cholinergic receptor, nicotinic, beta polypeptide 4
Synonyms: Acrb-4, Acrb4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 108015
VEGA: 9
HGNC: HGNC:1964
Homologene: 20196
Ccr2
Name: chemokine (C-C motif) receptor 2
Synonyms: CKR2, Cmkbr2, CC-CKR-2, CKR2B, CKR2A, CCR2B, CCR2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12772
HGNC: HGNC:1603
Homologene: 537
Strn
Name: striatin, calmodulin binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268980
Homologene: 2380
Prdm16
Name: PR domain containing 16
Synonyms: Mel1, line 27, 5730557K01Rik, csp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 70673
Homologene: 11139
Pdgfc
Name: platelet-derived growth factor, C polypeptide
Synonyms: 1110064L01Rik, PDGF-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 54635
HGNC: HGNC:8801
Homologene: 9423
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Rpa1
Name: replication protein A1
Synonyms: Rpa, RP-A, 5031405K23Rik, 70kDa, RF-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68275
Homologene: 2208
Tns3
Name: tensin 3
Synonyms: TEM6, Tens1, F830010I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 319939
Homologene: 49713
Eml4
Name: echinoderm microtubule associated protein like 4
Synonyms: 4930443C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78798
VEGA: 17
HGNC: HGNC:1316
Homologene: 56841
Triobp
Name: TRIO and F-actin binding protein
Synonyms: Tara, Mus EST 478828, EST478828
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110253
Homologene: 5104
Fblim1
Name: filamin binding LIM protein 1
Synonyms: Fblp1, 2410043F08Rik, migfilin, migfilin(s)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74202
Homologene: 56774
Bub3
Name: BUB3 mitotic checkpoint protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12237
HGNC: HGNC:1151
Homologene: 3470
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: 1200014O24Rik, Usp52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103135
VEGA: 10
Homologene: 5918
Rere
Name: arginine glutamic acid dipeptide (RE) repeats
Synonyms: eyem03Jus, Atr2, 1110033A15Rik, atrophin-2, eyes3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68703
HGNC: HGNC:9965
Homologene: 8101
Mcph1
Name: microcephaly, primary autosomal recessive 1
Synonyms: D030046N04Rik, 5430437K10Rik, BRIT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244329
HGNC: HGNC:6954
Homologene: 32586
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238130
VEGA: 12
Homologene: 56680
Mark3
Name: MAP/microtubule affinity regulating kinase 3
Synonyms: ETK-1, A430080F22Rik, C-TAK1, 1600015G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17169
VEGA: 12
HGNC: HGNC:6897
Homologene: 55653
Aimp1
Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Synonyms: 9830137A06Rik, AIMP1/p43, Emap2, Scye1, EMAPII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 13722
Homologene: 31260
Nfrkb
Name: nuclear factor related to kappa B binding protein
Synonyms: A530090G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235134
HGNC: HGNC:7802
Homologene: 4492
Il15ra
Name: interleukin 15 receptor, alpha chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16169
HGNC: HGNC:5978
Homologene: 1650
Ube3b
Name: ubiquitin protein ligase E3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 117146
Homologene: 13775
Rbl2
Name: RB transcriptional corepressor like 2
Synonyms: retinoblastoma-like 2, Rb2, p130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 19651
HGNC: HGNC:9894
Homologene: 4098
Med23
Name: mediator complex subunit 23
Synonyms: ESTM7, X83317, 3000002A17Rik, Sur2, Crsp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70208
HGNC: HGNC:2372
Homologene: 3552
Aldob
Name: aldolase B, fructose-bisphosphate
Synonyms: Aldo-2, Aldo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230163
HGNC: HGNC:417
Homologene: 20060
Tub
Name: tubby bipartite transcription factor
Synonyms: rd5, tub
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22141
Homologene: 31147
Kmt5b
Name: lysine methyltransferase 5B
Synonyms: Suv4-20h1, C630029K18Rik, Suv420h1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225888
Homologene: 32351
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, fibrocystin L, D86 mRNA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 192190
Homologene: 16332
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Olfr720
Name: olfactory receptor 720
Synonyms: MOR274-2, GA_x6K02T2PLTE-6544896-6543946
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258387
Homologene: 74036
Psma8
Name: proteasome (prosome, macropain) subunit, alpha type, 8
Synonyms: 2410072D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 73677
VEGA: 18
Homologene: 2086
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 192188
Homologene: 23022
Lonp1
Name: lon peptidase 1, mitochondrial
Synonyms: LON, 1200017E13Rik, Prss15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74142
VEGA: 17
HGNC: HGNC:9479
Homologene: 3521
Hrc
Name: histidine rich calcium binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15464
HGNC: HGNC:5178
Homologene: 137234
Camk2d
Name: calcium/calmodulin-dependent protein kinase II, delta
Synonyms: 8030469K03Rik, 2810011D23Rik, CaMK II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 108058
HGNC: HGNC:1462
Homologene: 55561
Treml4
Name: triggering receptor expressed on myeloid cells-like 4
Synonyms: 5031403H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224840
Homologene: null
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Ankar
Name: ankyrin and armadillo repeat containing
Synonyms: 4932422E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 319695
Homologene: 85163
Sema3d
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
Synonyms: 4631426B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 108151
Homologene: 23664
Phactr1
Name: phosphatase and actin regulator 1
Synonyms: 9630030F18Rik, Rpel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218194
Homologene: 33597
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 667060
HGNC: null
Homologene: null
Cspg4
Name: chondroitin sulfate proteoglycan 4
Synonyms: NG2, AN2, 4732461B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 121021
VEGA: 9
HGNC: HGNC:2466
Homologene: 20445
Acad12
Name: acyl-Coenzyme A dehydrogenase family, member 12
Synonyms: 9330129D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 338350
HGNC: null
Homologene: null
Krt78
Name: keratin 78
Synonyms: 2310030B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 332131
VEGA: 15
Homologene: 65261
Gm973
Name: predicted gene 973
Synonyms: LOC381260
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381260
Homologene: 124277
Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Synonyms: Slc21a6, 7330442B20Rik, mlst-1, Oatp1b2, Slc21a10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28253
Homologene: 75119
Zfp110
Name: zinc finger protein 110
Synonyms: NRIF, 2900024E01Rik, Nrif1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 65020
Homologene: 129707
Mylk
Name: myosin, light polypeptide kinase
Synonyms: MLCK108, A930019C19Rik, Mlck, nmMlck, telokin, MLCK210, 9530072E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Hipk3
Name: homeodomain interacting protein kinase 3
Synonyms: FIST3, DYRK6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15259
HGNC: HGNC:4915
Homologene: 55923
Thumpd3
Name: THUMP domain containing 3
Synonyms: Gtrosa26as
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14911
Homologene: 7351
Foxn1
Name: forkhead box N1
Synonyms: whn, Hfh11, D11Bhm185e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15218
Homologene: 2664
Olfr746
Name: olfactory receptor 746
Synonyms: GA_x6K02T2PMLR-6372116-6373060, MOR106-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258295
Homologene: 134081
Hs6st3
Name: heparan sulfate 6-O-sulfotransferase 3
Synonyms: 6OST3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 50787
VEGA: 14
Homologene: 89201
Tbxas1
Name: thromboxane A synthase 1, platelet
Synonyms: CYP5A1, CYP5, TXAS, TXS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 21391
Homologene: 130979
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: cytoplasmic linker protein 50, Rsn, 1110007I12Rik, CLIP-170, Clip 170, 4631429H07Rik, Clip50, restin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56430
Homologene: 74455
Slc22a19
Name: solute carrier family 22 (organic anion transporter), member 19
Synonyms: D630043A20Rik, Slc22a9, Oat5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 207151
Homologene: 133125
Sirpb1a
Name: signal-regulatory protein beta 1A
Synonyms: Sirpb1, 9930027N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 320832
Homologene: 82993
Hdac7
Name: histone deacetylase 7
Synonyms: Hdac7a, 5830434K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 56233
Homologene: 9124
Sgk2
Name: serum/glucocorticoid regulated kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27219
Homologene: 8446
Pnpt1
Name: polyribonucleotide nucleotidyltransferase 1
Synonyms: polynucleotide phosphorylase, 1200003F12Rik, PNPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71701
Homologene: 12404
Olfr167
Name: olfactory receptor 167
Synonyms: GA_x54KRFPKG5P-15963726-15962788, MOR272-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258937
Homologene: 78689
Afmid
Name: arylformamidase
Synonyms: formylkynureninase, formylase, Kf, 9030621K19Rik, kynurenine formamidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71562
Homologene: 41731
Slco2a1
Name: solute carrier organic anion transporter family, member 2a1
Synonyms: mPgt, Pgt, Slc21a2, 2310021C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 24059
Homologene: 38077
Slc36a4
Name: solute carrier family 36 (proton/amino acid symporter), member 4
Synonyms: PAT4, 6330573I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234967
Homologene: 56300
Zfp512b
Name: zinc finger protein 512B
Synonyms: LOC269401, Znf512b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269401
Homologene: 69314
Olfr1053
Name: olfactory receptor 1053
Synonyms: GA_x6K02T2Q125-47793414-47792471, Olfr1053-ps1, MOR187-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257974
Homologene: 74197
Msrb2
Name: methionine sulfoxide reductase B2
Synonyms: 2310050L06Rik, Msrb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76467
Homologene: 56555
Slc26a1
Name: solute carrier family 26 (sulfate transporter), member 1
Synonyms: Sat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231583
Homologene: 32539
Olfr203
Name: olfactory receptor 203
Synonyms: MOR182-5, GA_x54KRFPKG5P-55517445-55518365
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258479
HGNC: null
Homologene: 122781
Olfr612
Name: olfactory receptor 612
Synonyms: GA_x6K02T2PBJ9-6251685-6250741, EG545985, MOR15-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 545985
HGNC: null
Homologene: 79675
Olfr619
Name: olfactory receptor 619
Synonyms: GA_x6K02T2PBJ9-6326488-6327450, MOR31-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259080
HGNC: null
Homologene: 45095
Zfp322a
Name: zinc finger protein 322A
Synonyms: 9630054P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218100
Homologene: 23460
Tspan8
Name: tetraspanin 8
Synonyms: Tm4sf3, E330007O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216350
VEGA: 10
Homologene: 20968
Vmn2r43
Name: vomeronasal 2, receptor 43
Synonyms: EC2-V2R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381838
HGNC: null
Homologene: 113703
Ac130840.1
Name: Uncharacterized protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 59,562,771 bp
  • C to T, chromosome 1 at 72,658,441 bp
  • A to G, chromosome 2 at 11,723,523 bp
  • T to G, chromosome 2 at 19,393,221 bp
  • C to G, chromosome 2 at 86,315,154 bp
  • T to C, chromosome 2 at 104,471,173 bp
  • A to G, chromosome 2 at 163,004,160 bp
  • G to A, chromosome 2 at 181,587,085 bp
  • T to C, chromosome 3 at 15,379,081 bp
  • C to T, chromosome 3 at 64,504,221 bp
  • C to T, chromosome 3 at 81,209,245 bp
  • T to A, chromosome 3 at 93,727,272 bp
  • G to T, chromosome 3 at 126,795,353 bp
  • A to C, chromosome 3 at 132,677,099 bp
  • G to A, chromosome 4 at 49,538,171 bp
  • T to C, chromosome 4 at 123,489,212 bp
  • A to T, chromosome 4 at 141,584,864 bp
  • T to A, chromosome 4 at 150,615,733 bp
  • A to T, chromosome 4 at 154,355,361 bp
  • T to A, chromosome 5 at 12,563,318 bp
  • T to C, chromosome 5 at 12,584,998 bp
  • T to A, chromosome 5 at 108,672,472 bp
  • C to T, chromosome 5 at 114,399,865 bp
  • T to C, chromosome 5 at 121,604,259 bp
  • A to G, chromosome 5 at 123,623,218 bp
  • A to G, chromosome 6 at 38,948,641 bp
  • A to G, chromosome 6 at 113,055,877 bp
  • A to T, chromosome 6 at 141,683,225 bp
  • A to G, chromosome 7 at 8,255,551 bp
  • C to T, chromosome 7 at 12,848,502 bp
  • A to T, chromosome 7 at 45,336,214 bp
  • A to T, chromosome 7 at 103,538,994 bp
  • A to G, chromosome 7 at 103,604,012 bp
  • G to A, chromosome 7 at 109,027,835 bp
  • G to A, chromosome 7 at 131,570,875 bp
  • C to T, chromosome 7 at 141,648,101 bp
  • T to G, chromosome 8 at 18,689,065 bp
  • T to C, chromosome 8 at 91,085,462 bp
  • T to A, chromosome 9 at 15,734,210 bp
  • T to A, chromosome 9 at 31,414,684 bp
  • A to G, chromosome 9 at 55,034,818 bp
  • G to C, chromosome 9 at 56,890,478 bp
  • T to A, chromosome 9 at 103,079,454 bp
  • C to T, chromosome 9 at 124,106,793 bp
  • T to A, chromosome 10 at 24,910,766 bp
  • A to C, chromosome 10 at 86,896,496 bp
  • A to G, chromosome 10 at 115,844,130 bp
  • T to C, chromosome 10 at 128,320,413 bp
  • T to A, chromosome 11 at 8,435,738 bp
  • A to G, chromosome 11 at 29,141,256 bp
  • T to C, chromosome 11 at 59,067,729 bp
  • A to G, chromosome 11 at 75,306,176 bp
  • T to C, chromosome 11 at 78,365,937 bp
  • A to C, chromosome 11 at 117,836,474 bp
  • A to T, chromosome 11 at 118,096,536 bp
  • T to C, chromosome 12 at 40,779,642 bp
  • A to T, chromosome 12 at 111,615,441 bp
  • A to T, chromosome 13 at 23,356,904 bp
  • G to A, chromosome 13 at 43,123,068 bp
  • A to T, chromosome 14 at 14,175,446 bp
  • T to A, chromosome 14 at 50,653,364 bp
  • T to C, chromosome 14 at 119,138,476 bp
  • G to T, chromosome 15 at 44,529,713 bp
  • T to C, chromosome 15 at 78,966,708 bp
  • G to A, chromosome 15 at 97,806,505 bp
  • T to C, chromosome 15 at 101,946,168 bp
  • G to A, chromosome 16 at 19,514,836 bp
  • T to C, chromosome 16 at 34,880,303 bp
  • T to C, chromosome 16 at 59,303,728 bp
  • T to A, chromosome 17 at 48,272,793 bp
  • T to C, chromosome 17 at 56,615,068 bp
  • T to C, chromosome 17 at 78,692,499 bp
  • T to C, chromosome 17 at 83,410,193 bp
  • T to A, chromosome 18 at 12,453,863 bp
  • T to G, chromosome 18 at 14,730,976 bp
  • T to C, chromosome 19 at 3,804,907 bp
  • A to G, chromosome 19 at 7,683,859 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1975 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039988-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.