Strain Name:
C57BL/6J-MtgxR1978Btlr/Mmmh
Stock Number:
039991-MU
Citation ID:
RRID:MMRRC_039991-MU
Other Names:
R1978 (G1), C57BL/6J-MtgxR1978Btlr
Major Collection:

Strain Information

Smyd1
Name: SET and MYND domain containing 1
Synonyms: 4632404M21Rik, Bop
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12180
Homologene: 7645
Ncoa7
Name: nuclear receptor coactivator 7
Synonyms: 9030406N13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 211329
VEGA: 10
Homologene: 65245
Nln
Name: neurolysin (metallopeptidase M3 family)
Synonyms: 4930472G13Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75805
VEGA: 13
Homologene: 69315
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 4632408O18Rik, TRS130, Nibp, 1810044A24Rik, 2900005P22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Hnrnpll
Name: heterogeneous nuclear ribonucleoprotein L-like
Synonyms: Hnrpll, 2810036L13Rik, 2510028H02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72692
Homologene: 26701
Zc3h14
Name: zinc finger CCCH type containing 14
Synonyms: 1700016A15Rik, 1010001P15Rik, 2700069A02Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75553
VEGA: 12
Homologene: 32605
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108989
Homologene: 37753
Miga1
Name: mitoguardin 1
Synonyms: C030011O14Rik, Fam73a, Mita1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 215708
Homologene: 18369
Akap12
Name: A kinase anchor protein 12
Synonyms: Tsga12, SSeCKS, Srcs5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83397
VEGA: 10
HGNC: HGNC:370
Homologene: 3740
Resf1
Name: retroelement silencing factor 1
Synonyms: 2810474O19Rik, GET
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67246
Homologene: 19251
Heatr5a
Name: HEAT repeat containing 5A
Synonyms: D930036F22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320487
VEGA: 12
Homologene: 19635
Plcg1
Name: phospholipase C, gamma 1
Synonyms: Plc-gamma1, Plc-1, Plcg-1, Cded
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18803
HGNC: HGNC:9065
Homologene: 1997
Tbc1d23
Name: TBC1 domain family, member 23
Synonyms: D030022P07Rik, 4930451A13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67581
VEGA: 16
Homologene: 10126
Stag1
Name: STAG1 cohesin complex component
Synonyms: Scc3, SA-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20842
Homologene: 21191
Rbbp6
Name: retinoblastoma binding protein 6, ubiquitin ligase
Synonyms: C030034J04Rik, 4933422O15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19647
HGNC: HGNC:9889
Homologene: 136812
Skic3
Name: SKI3 subunit of superkiller complex
Synonyms: Ttc37
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218343
VEGA: 13
Homologene: 40966
Rif1
Name: replication timing regulatory factor 1
Synonyms: 6530403D07Rik, D2Ertd145e, 5730435J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51869
Homologene: 41231
Phyhipl
Name: phytanoyl-CoA hydroxylase interacting protein-like
Synonyms: 4921522K17Rik, PHY2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70911
Homologene: 13028
Pno1
Name: partner of NOB1 homolog
Synonyms: expressed during mesenchymal induction 3, Emi3, Imi3, 1810003N24Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66249
Homologene: 6961
Snx29
Name: sorting nexin 29
Synonyms: Gm11170, LOC381035, Rundc2a, LOC385605, 4933437K13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74478
Homologene: 32706
Tle3
Name: transducin-like enhancer of split 3
Synonyms: ESG, 2610103N05Rik, Grg3a, Grg3b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21887
Homologene: 21059
Inpp5j
Name: inositol polyphosphate 5-phosphatase J
Synonyms: Pib5pa, Pipp
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170835
HGNC: HGNC:8956
Homologene: 8682
Kif13a
Name: kinesin family member 13A
Synonyms: N-3 kinesin, 4930505I07Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Mpdz
Name: multiple PDZ domain crumbs cell polarity complex component
Synonyms: MUPP1, B930003D11Rik, multiple PDZ domain protein
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17475
HGNC: HGNC:7208
Homologene: 2841
Mkln1
Name: muskelin 1, intracellular mediator containing kelch motifs
Synonyms: A130067F06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27418
HGNC: HGNC:7109
Homologene: 8305
P3h1
Name: prolyl 3-hydroxylase 1
Synonyms: 2410024C15Rik, Leprecan, Lepre1, Gros1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56401
Homologene: 10509
Porcn
Name: porcupine O-acyltransferase
Synonyms: mMg61, porc, 2410004O13Rik, Mporc, DXHXS7465e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 53627
Homologene: 41529
Sbsn
Name: suprabasin
Synonyms: 1110005D19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 282619
Homologene: 17900
Cep192
Name: centrosomal protein 192
Synonyms: D430014P18Rik, 4631422C13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70799
VEGA: 18
Homologene: 73526
Pitpnm1
Name: phosphatidylinositol transfer protein, membrane-associated 1
Synonyms: RdgB, DRES9
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18739
HGNC: HGNC:9003
Homologene: 3608
Myo6
Name: myosin VI
Synonyms: Tlc, Myo6rsv, rsv
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17920
HGNC: HGNC:7605
Homologene: 56417
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 1110021D17Rik, Polydom, D430029O09Rik, 4833413O10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64817
Homologene: 23386
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240411
Myo1g
Name: myosin IG
Synonyms: E430002D17Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246177
Homologene: 27996
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Adcy3
Name: adenylate cyclase 3
Synonyms: AC3, ACIII
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104111
HGNC: HGNC:234
Homologene: 2978
Pfdn6
Name: prefoldin subunit 6
Synonyms: H-2Ke2, Ke-2, H2-Ke2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14976
HGNC: HGNC:4926
Homologene: 40720
Pnldc1
Name: poly(A)-specific ribonuclease (PARN)-like domain containing 1
Synonyms: LOC240023
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240023
VEGA: 17
Homologene: 15054
Vmn2r3
Name: vomeronasal 2, receptor 3
Synonyms: EG637004
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 637004
Vwa3a
Name: von Willebrand factor A domain containing 3A
Synonyms: E030013G06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233813
Homologene: 18607
Cpt2
Name: carnitine palmitoyltransferase 2
Synonyms: CPTII, CPT II
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12896
HGNC: HGNC:2330
Homologene: 77
Or5j1
Name: olfactory receptor family 5 subfamily J member 1
Synonyms: MOR172-6, MOR172-8_p, Olfr1106, GA_x6K02T2Q125-48541463-48540525
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258747
Homologene: 27251
Prkcg
Name: protein kinase C, gamma
Synonyms: Pkcc, PKCgamma, Prkcc
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18752
HGNC: HGNC:9402
Homologene: 20602
Mybph
Name: myosin binding protein H
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53311
HGNC: HGNC:7552
Homologene: 3661
Unc13a
Name: unc-13 homolog A
Synonyms: Munc13-1, 2410078G03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382018
Homologene: 11279
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Tmem144
Name: transmembrane protein 144
Synonyms: 5730537D05Rik, 1110057I03Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70652
Homologene: 41250
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Olfm5
Name: olfactomedin 5
Synonyms: E030002O03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244180
Homologene: 18253
Hck
Name: hemopoietic cell kinase
Synonyms: Hck-1, Bmk
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15162
HGNC: HGNC:4840
Homologene: 20489
Cfap57
Name: cilia and flagella associated protein 57
Synonyms: C130004B06Rik, Wdr65, LOC384050, 1110020C03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68625
Homologene: 51350
Or10ak7
Name: olfactory receptor family 10 subfamily AK member 7
Synonyms: MOR259-1, MOR259-13, GA_x6K02T2QD9B-18602750-18603691, MOR259-1, Olfr1328, Olfr1519
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258394
Homologene: 121524
Slc6a13
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 13
Synonyms: Gabt3, Gat2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14412
Homologene: 9592
Or6p1
Name: olfactory receptor family 6 subfamily P member 1
Synonyms: MOR103-10, Olfr414, GA_x6K02T2P20D-20749615-20748662
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258756
Homologene: 17383
0610040J01Rik
Name: RIKEN cDNA 0610040J01 gene
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76261
Homologene: 49537
Cenpu
Name: centromere protein U
Synonyms: Mlf1ip, 1700029A22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71876
Homologene: 11629
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Synonyms: NSS2, SNS2, NaT, NaN
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24046
VEGA: 9
Homologene: 8041
Xirp1
Name: xin actin-binding repeat containing 1
Synonyms: Cmya1, mXin alpha, Xin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22437
VEGA: 9
Homologene: 7998
Or4d11
Name: olfactory receptor family 4 subfamily D member 11
Synonyms: MOR239-3, Olfr1423, GA_x6K02T2RE5P-2393361-2392429
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258675
Homologene: 128078
Tchh
Name: trichohyalin
Synonyms: AHF, Thh
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99681
Homologene: 136273
Muc21
Name: mucin 21
Synonyms: Gm9573, epiglycanin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 672682
Cyp4a12b
Name: cytochrome P450, family 4, subfamily a, polypeptide 12B
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13118
Homologene: 134044
Hhat
Name: hedgehog acyltransferase
Synonyms: Skn, 2810432O22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226861
Homologene: 41232
Ankrd53
Name: ankyrin repeat domain 53
Synonyms: 4930564N15Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 75305
Homologene: 49810
4921539E11Rik
Name: RIKEN cDNA 4921539E11 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70941
Homologene: 52843
Apol7b
Name: apolipoprotein L 7b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 278679
HGNC: HGNC:619
Homologene: 40940
Slfn5
Name: schlafen 5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327978
Homologene: 18839
Scly
Name: selenocysteine lyase
Synonyms: Scly1, SCL, A930015N15Rik, Scly2, Selenocysteine reductase
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 50880
Homologene: 9548
Dbx2
Name: developing brain homeobox 2
Synonyms: 9430056A22Rik, LOC383001
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223843
Homologene: 54981
Trim38
Name: tripartite motif-containing 38
Synonyms: LOC214158
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214158
Homologene: 48427
Or7a39
Name: olfactory receptor family 7 subfamily A member 39
Synonyms: MOR139-6, Olfr1355, GA_x6K02T2QGN0-2932609-2931677
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 257734
Homologene: 136441
Vmn1r26
Name: vomeronasal 1 receptor 26
Synonyms: V1rc17
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171190
Hoxc6
Name: homeobox C6
Synonyms: Hox-6.1, Hox-3.3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15425
HGNC: HGNC:5128
Homologene: 19533
Crisp4
Name: cysteine-rich secretory protein 4
Synonyms: 9230112K08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 78081
HGNC: HGNC:304
Homologene: 81683
Or6b3
Name: olfactory receptor family 6 subfamily B member 3
Synonyms: MOR103-2, Olfr1414, GA_x6K02T2R7CC-81245243-81246181
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 259041
Homologene: 88368
Commd8
Name: COMM domain containing 8
Synonyms: IMAGE:1958590, D5Buc26e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 27784
Homologene: 9873
Fam220a
Name: family with sequence similarity 220, member A
Synonyms: 1500026F15Rik, 2810453I06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67238
Homologene: 57041
Vmn1r12
Name: vomeronasal 1 receptor 12
Synonyms: Gm6674
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 626397
Homologene: 74373
Ggnbp1
Name: gametogenetin binding protein 1
Synonyms: 0610031G08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70772
Homologene: 79568
Gm14569
Name: predicted gene 14569
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 101055983
Homologene: 141085
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 18,128,665 bp
  • A to G, chromosome 1 at 91,320,169 bp
  • C to A, chromosome 1 at 92,511,777 bp
  • C to A, chromosome 1 at 134,196,996 bp
  • T to G, chromosome 1 at 150,419,907 bp
  • A to G, chromosome 1 at 153,133,597 bp
  • T to A, chromosome 1 at 174,431,091 bp
  • A to G, chromosome 1 at 192,717,107 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • T to C, chromosome 2 at 52,287,345 bp
  • A to T, chromosome 2 at 76,811,243 bp
  • C to T, chromosome 2 at 87,048,835 bp
  • G to T, chromosome 2 at 153,129,856 bp
  • A to G, chromosome 2 at 160,752,578 bp
  • T to A, chromosome 3 at 64,287,290 bp
  • T to C, chromosome 3 at 79,825,400 bp
  • T to C, chromosome 3 at 93,446,799 bp
  • CCAGGGCAG to CCAG, chromosome 3 at 152,335,304 bp
  • C to A, chromosome 4 at 58,097,292 bp
  • T to C, chromosome 4 at 81,378,481 bp
  • T to A, chromosome 4 at 103,270,764 bp
  • T to C, chromosome 4 at 107,904,567 bp
  • A to T, chromosome 4 at 115,438,145 bp
  • A to G, chromosome 4 at 118,593,132 bp
  • A to T, chromosome 4 at 118,934,184 bp
  • A to T, chromosome 4 at 119,247,976 bp
  • T to C, chromosome 5 at 14,713,795 bp
  • C to T, chromosome 5 at 62,882,250 bp
  • T to A, chromosome 5 at 63,898,537 bp
  • T to C, chromosome 5 at 72,165,499 bp
  • C to A, chromosome 5 at 143,563,127 bp
  • C to T, chromosome 6 at 31,490,530 bp
  • T to A, chromosome 6 at 57,159,509 bp
  • T to C, chromosome 6 at 58,009,126 bp
  • A to T, chromosome 6 at 71,312,719 bp
  • T to G, chromosome 6 at 73,121,970 bp
  • C to A, chromosome 6 at 83,763,203 bp
  • A to T, chromosome 6 at 121,332,373 bp
  • T to A, chromosome 6 at 149,326,432 bp
  • T to A, chromosome 7 at 3,305,346 bp
  • T to C, chromosome 7 at 30,754,988 bp
  • A to G, chromosome 7 at 42,613,841 bp
  • T to A, chromosome 7 at 104,164,741 bp
  • A to G, chromosome 7 at 120,758,954 bp
  • G to T, chromosome 7 at 122,999,488 bp
  • G to A, chromosome 8 at 46,562,653 bp
  • A to G, chromosome 8 at 71,644,980 bp
  • T to A, chromosome 9 at 61,394,633 bp
  • A to T, chromosome 9 at 80,228,925 bp
  • T to G, chromosome 9 at 100,888,086 bp
  • A to G, chromosome 9 at 108,114,549 bp
  • G to A, chromosome 9 at 119,780,795 bp
  • C to T, chromosome 9 at 120,018,591 bp
  • A to G, chromosome 10 at 4,313,855 bp
  • A to G, chromosome 10 at 30,691,299 bp
  • A to C, chromosome 10 at 70,559,761 bp
  • A to G, chromosome 10 at 78,879,280 bp
  • G to A, chromosome 11 at 3,502,150 bp
  • T to C, chromosome 11 at 6,520,829 bp
  • T to C, chromosome 11 at 17,204,519 bp
  • T to C, chromosome 11 at 82,956,616 bp
  • C to T, chromosome 12 at 4,194,314 bp
  • A to T, chromosome 12 at 51,939,658 bp
  • T to G, chromosome 12 at 98,763,922 bp
  • T to C, chromosome 13 at 23,791,098 bp
  • A to G, chromosome 13 at 46,848,391 bp
  • T to C, chromosome 13 at 76,134,815 bp
  • A to T, chromosome 13 at 104,036,995 bp
  • A to T, chromosome 15 at 73,000,025 bp
  • A to C, chromosome 15 at 77,423,339 bp
  • C to T, chromosome 15 at 95,632,353 bp
  • T to C, chromosome 15 at 103,010,007 bp
  • T to A, chromosome 16 at 11,367,724 bp
  • T to C, chromosome 16 at 57,189,351 bp
  • A to G, chromosome 17 at 12,906,505 bp
  • A to G, chromosome 17 at 27,029,543 bp
  • G to A, chromosome 17 at 33,939,077 bp
  • T to A, chromosome 17 at 35,622,965 bp
  • A to G, chromosome 17 at 80,044,518 bp
  • T to C, chromosome 18 at 67,803,158 bp
  • T to A, chromosome 18 at 77,321,642 bp
  • C to T, chromosome 19 at 4,107,973 bp
  • T to C, chromosome 19 at 12,036,341 bp
  • A to G, chromosome X at 8,204,301 bp
  • A to C, chromosome X at 36,432,128 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1978 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039991-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.