Strain Name:
C57BL/6J-MtgxR2000Btlr/Mmmh
Stock Number:
040010-MU
Citation ID:
RRID:MMRRC_040010-MU
Other Names:
R2000 (G1), C57BL/6J-MtgxR2000Btlr
Major Collection:

Gene Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Atf2
Name: activating transcription factor 2
Synonyms: ATF-2, D130078H02Rik, Creb2, CRE-BP, mXBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11909
HGNC: HGNC:784
Homologene: 31061
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: Dhm2, mXrn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 24127
Homologene: 5894
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Gp330, Megalin, D230004K18Rik, b2b1625.2Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Smarcad1
Name: SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Synonyms: Etl1, D6Pas1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13990
Homologene: 5301
Lgals9
Name: lectin, galactose binding, soluble 9
Synonyms: gal-9, Lgals5, LGALS35, galectin-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16859
Homologene: 134662
Zfp101
Name: zinc finger protein 101
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22643
Homologene: 137226
Brpf3
Name: bromodomain and PHD finger containing, 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268936
Homologene: 16092
Dnmt3b
Name: DNA methyltransferase 3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13436
HGNC: HGNC:2979
Homologene: 56000
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208146
VEGA: 16
Homologene: 9967
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: A430032G04Rik, apollon, D630005A10Rik, A430040A19Rik, Bruce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12211
Homologene: 7248
Tlk1
Name: tousled-like kinase 1
Synonyms: 4930545J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228012
Homologene: 130657
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: VPARP, Adprtl1, VAULT3, PH5P, p193, E230037B21Rik, C030027K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Rif1
Name: replication timing regulatory factor 1
Synonyms: D2Ertd145e, 5730435J01Rik, 6530403D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51869
Homologene: 41231
Cip2a
Name: cell proliferation regulating inhibitor of protein phosphatase 2A
Synonyms: C330027C09Rik, Cip2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224171
Homologene: 10842
Wwc1
Name: WW, C2 and coiled-coil domain containing 1
Synonyms: Kibra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 211652
Homologene: 69180
Rsbn1l
Name: round spermatid basic protein 1-like
Synonyms: C330002G24Rik, 8430412F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 242860
Homologene: 19435
Crebbp
Name: CREB binding protein
Synonyms: CBP, KAT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Fosl1
Name: fos-like antigen 1
Synonyms: fra-1, Fra1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14283
VEGA: 19
Homologene: 3967
Btnl9
Name: butyrophilin-like 9
Synonyms: D330012D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237754
Homologene: 68540
Hadh
Name: hydroxyacyl-Coenzyme A dehydrogenase
Synonyms: Schad, Hadhsc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 15107
HGNC: HGNC:4799
Homologene: 55888
Ctsa
Name: cathepsin A
Synonyms: Ppgb, PPCA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19025
HGNC: HGNC:9251
Homologene: 80163
Itsn2
Name: intersectin 2
Synonyms: Sh3p18, Sh3d1B, Eh domain, SH3 domain regulator of endocytosis 2, Ese2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20403
VEGA: 12
HGNC: HGNC:6184
Homologene: 22627
Casp8ap2
Name: caspase 8 associated protein 2
Synonyms: D4Ertd659e, FLASH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 26885
HGNC: HGNC:1510
Homologene: 8066
Ufsp1
Name: UFM1-specific peptidase 1
Synonyms: D5Ertd655e, 2700038N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70240
Homologene: 80245
Gzf1
Name: GDNF-inducible zinc finger protein 1
Synonyms: 8430437G08Rik, Zfp336
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74533
Homologene: 11200
Dync1li1
Name: dynein cytoplasmic 1 light intermediate chain 1
Synonyms: Dnclic1, 1110053F02Rik, LIC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235661
VEGA: 9
Homologene: 9403
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218333
VEGA: 13
Homologene: 18902
Camk1d
Name: calcium/calmodulin-dependent protein kinase ID
Synonyms: E030025C11Rik, A630059D12Rik, CaMKIdelta, CKLiK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227541
Homologene: 121858
Flt3
Name: FMS-like tyrosine kinase 3
Synonyms: Flk2, CD135, Flt-3, wmfl, Flk-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14255
HGNC: HGNC:3765
Homologene: 3040
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC1, NBC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54403
Homologene: 55776
Htr5a
Name: 5-hydroxytryptamine (serotonin) receptor 5A
Synonyms: Htr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 15563
HGNC: HGNC:5300
Homologene: 22461
Ttn
Name: titin
Synonyms: D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, mdm, 1100001C23Rik, shru, connectin, L56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 672511
Homologene: 45439
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 631797
Homologene: 53396
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Kif1a
Name: kinesin family member 1A
Synonyms: LOC381283, N-3 kinesin, Kns1, C630002N23Rik, ATSV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: Moca, PBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Ttf1
Name: transcription termination factor, RNA polymerase I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22130
Homologene: 137223
Ppp1r9b
Name: protein phosphatase 1, regulatory subunit 9B
Synonyms: Spn, neurabin II, SPL, spinophilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217124
HGNC: HGNC:9298
Homologene: 32787
Myo1c
Name: myosin IC
Synonyms: myosin-Ibeta, C80397, mm1beta, myr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Ush1c
Name: USH1 protein network component harmonin
Synonyms: Usher syndrome 1C, 2010016F01Rik, harmonin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72088
Homologene: 77476
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mar, Mart1, Mor1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 353326
VEGA: 12
Homologene: 120261
Pnmal1
Name: PNMA-like 1
Synonyms: 0710005I19Rik, 4930488B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71691
Homologene: 10073
Tectb
Name: tectorin beta
Synonyms: Tctnb, [b]-tectorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 21684
Homologene: 7568
Gpr108
Name: G protein-coupled receptor 108
Synonyms: 1810015L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78308
VEGA: 17
Homologene: 32495
Rasip1
Name: Ras interacting protein 1
Synonyms: 2610025P08Rik, Rain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69903
Homologene: 9847
Olfr1155
Name: olfactory receptor 1155
Synonyms: MOR174-10, GA_x6K02T2Q125-49426894-49425950
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258636
Homologene: 133739
Cd46
Name: CD46 antigen, complement regulatory protein
Synonyms: CD46, Mcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17221
HGNC: HGNC:6953
Homologene: 7832
Gm15446
Name: predicted gene 15446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100642166
Lvrn
Name: laeverin
Synonyms: Aqpep, 4833403I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 74574
VEGA: 18
Homologene: 51352
Gstm1
Name: glutathione S-transferase, mu 1
Synonyms: Gstb-1, Gstb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14862
HGNC: HGNC:4637
Homologene: 115474
Gm4759
Name: predicted gene 4759
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 209380
RP23-334I5.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
Gata6
Name: GATA binding protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 14465
VEGA: 18
HGNC: HGNC:4174
Homologene: 68449
Olfr401
Name: olfactory receptor 401
Synonyms: GA_x6K02T2P1NL-4278037-4278984, MOR255-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258701
HGNC: HGNC:8282
Homologene: 73922
Dph7
Name: diphthamine biosynethesis 7
Synonyms: 2810443J12Rik, Wdr85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67228
Homologene: 5432
Gmppa
Name: GDP-mannose pyrophosphorylase A
Synonyms: 1810012N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 69080
Homologene: 8346
Olfr981
Name: olfactory receptor 981
Synonyms: MOR223-8, GA_x6K02T2PVTD-33720892-33721824
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258283
VEGA: 9
Homologene: 64849
Gabrr2
Name: gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14409
HGNC: HGNC:4091
Homologene: 20471
Uox
Name: urate oxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22262
Homologene: 7584
Nkain2
Name: Na+/K+ transporting ATPase interacting 2
Synonyms: 6330571D19Rik, Tcba1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 432450
Homologene: 65073
Ifnl3
Name: interferon lambda 3
Synonyms: INF-lambda, Il28, Il28b, IFL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 338374
Homologene: 77540
Magea10
Name: melanoma antigen family A, 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 236852
HGNC: HGNC:6797
Homologene: 121621
Pth2
Name: parathyroid hormone 2
Synonyms: Tifp39, TIP39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 114640
Homologene: 14235
Gm10767
Name: predicted gene 10767
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100038538
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 75,441,528 bp
  • G to T, chromosome 1 at 93,054,329 bp
  • A to G, chromosome 1 at 195,077,704 bp
  • A to T, chromosome 2 at 5,362,025 bp
  • T to A, chromosome 2 at 24,971,641 bp
  • T to A, chromosome 2 at 29,065,185 bp
  • T to A, chromosome 2 at 52,081,298 bp
  • A to T, chromosome 2 at 52,212,970 bp
  • A to G, chromosome 2 at 69,467,090 bp
  • T to C, chromosome 2 at 70,745,489 bp
  • T to C, chromosome 2 at 73,863,240 bp
  • A to T, chromosome 2 at 76,969,703 bp
  • G to A, chromosome 2 at 87,943,146 bp
  • T to C, chromosome 2 at 130,935,588 bp
  • T to C, chromosome 2 at 148,684,611 bp
  • A to G, chromosome 2 at 153,684,487 bp
  • A to G, chromosome 2 at 164,834,001 bp
  • A to G, chromosome 3 at 108,014,811 bp
  • A to T, chromosome 3 at 131,245,239 bp
  • A to C, chromosome 3 at 146,610,399 bp
  • T to A, chromosome 4 at 32,634,874 bp
  • T to A, chromosome 4 at 33,084,400 bp
  • T to C, chromosome 4 at 139,616,313 bp
  • G to A, chromosome 5 at 20,902,370 bp
  • G to A, chromosome 5 at 27,850,889 bp
  • C to T, chromosome 5 at 89,028,347 bp
  • T to C, chromosome 5 at 109,942,811 bp
  • T to C, chromosome 5 at 137,294,904 bp
  • T to C, chromosome 5 at 147,341,238 bp
  • A to G, chromosome 6 at 65,073,216 bp
  • T to A, chromosome 7 at 16,961,039 bp
  • G to T, chromosome 7 at 28,522,929 bp
  • C to A, chromosome 7 at 45,181,722 bp
  • T to C, chromosome 7 at 45,638,673 bp
  • A to G, chromosome 7 at 46,221,433 bp
  • G to A, chromosome 7 at 106,423,231 bp
  • A to G, chromosome 9 at 40,022,689 bp
  • C to T, chromosome 9 at 96,045,563 bp
  • A to G, chromosome 9 at 106,992,961 bp
  • C to A, chromosome 9 at 114,713,563 bp
  • T to A, chromosome 10 at 32,890,285 bp
  • A to T, chromosome 11 at 35,876,547 bp
  • T to C, chromosome 11 at 49,169,121 bp
  • A to G, chromosome 11 at 74,121,580 bp
  • A to T, chromosome 11 at 75,670,579 bp
  • T to C, chromosome 11 at 78,973,170 bp
  • A to G, chromosome 11 at 94,996,620 bp
  • A to T, chromosome 11 at 119,436,022 bp
  • T to A, chromosome 12 at 4,666,176 bp
  • C to A, chromosome 12 at 109,593,887 bp
  • A to T, chromosome 13 at 66,908,150 bp
  • C to T, chromosome 13 at 70,602,427 bp
  • C to T, chromosome 14 at 56,613,724 bp
  • G to A, chromosome 15 at 58,602,311 bp
  • A to T, chromosome 16 at 4,084,252 bp
  • G to A, chromosome 16 at 20,186,391 bp
  • A to T, chromosome 16 at 49,014,969 bp
  • A to C, chromosome 17 at 28,821,557 bp
  • C to T, chromosome 17 at 33,381,517 bp
  • C to T, chromosome 17 at 57,236,712 bp
  • T to C, chromosome 17 at 74,604,619 bp
  • T to C, chromosome 18 at 11,054,113 bp
  • A to T, chromosome 18 at 46,905,307 bp
  • A to G, chromosome 19 at 5,450,355 bp
  • C to G, chromosome 19 at 55,180,999 bp
  • A to T, chromosome X at 72,382,773 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2000 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040010-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.