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Strain Name:
C57BL/6J-MtgxR2005Btlr/Mmmh
Stock Number:
040014-MU
Citation ID:
RRID:MMRRC_040014-MU
Other Names:
R2005 (G1), C57BL/6J-MtgxR2005Btlr
Major Collection:

Strain Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: dyn, SpbIV, neuroaxonal dystrophy, 5830426A08Rik, ROSA62, nmf261, 1700022P15Rik, Spnb4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80297
Homologene: 11879
Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 271639
Homologene: 10188
Spidr
Name: scaffolding protein involved in DNA repair
Synonyms: 2310008H04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224008
VEGA: 16
Homologene: 51693
Cdkn1b
Name: cyclin dependent kinase inhibitor 1B
Synonyms: p27Kip1, p27
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12576
HGNC: HGNC:1785
Homologene: 2999
Fbxo36
Name: F-box protein 36
Synonyms: 0610008D19Rik, 2410002G19Rik, 1110020F21Rik, D1Ertd757e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66153
Homologene: 11927
Cwf19l2
Name: CWF19 like cell cycle control factor 2
Synonyms: 3230401L03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244672
Homologene: 12366
Tgds
Name: TDP-glucose 4,6-dehydratase
Synonyms: 2610017J16Rik, 2610025M23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76355
VEGA: 14
Homologene: 129708
Ddx10
Name: DEAD box helicase 10
Synonyms: 4632415A01Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77591
VEGA: 9
HGNC: HGNC:2735
Homologene: 20922
Ddx50
Name: DExD box helicase 50
Synonyms: GU2, RH-II/Gubeta, 4933429B04Rik, 8430408E17Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 94213
VEGA: 10
Homologene: 56986
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: Rnf164, D930043C02Rik, 2900024N03Rik, 9430019J22Rik, Mnab
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319817
Homologene: 28276
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Nf-1, Dsk9, Mhdadsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Tasp1
Name: taspase, threonine aspartase 1
Synonyms: 4930485D02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75812
Homologene: 9795
Vangl1
Name: VANGL planar cell polarity 1
Synonyms: Lpp2, mStbm, stbm, KITENIN
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229658
Homologene: 44540
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57752
Homologene: 5087
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227648
Homologene: 10533
Eif4h
Name: eukaryotic translation initiation factor 4H
Synonyms: Wscr1, Eif4h, D5Ertd355e, E430026L18Rik, Wbscr1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22384
Homologene: 32536
Wdr1
Name: WD repeat domain 1
Synonyms: D5Wsu185e, Aip1, rede
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22388
Homologene: 6628
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki-67, D630048A14Rik, Ki67
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Gng4
Name: guanine nucleotide binding protein (G protein), gamma 4
Synonyms: 4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14706
HGNC: HGNC:4407
Homologene: 3299
F2rl1
Name: F2R like trypsin receptor 1
Synonyms: PAR-2, Par2, Protease-activated receptor-2, Gpcr11, proteinase-activated receptor-2, coagulation factor II (thrombin) receptor-like 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14063
VEGA: 13
HGNC: HGNC:3538
Homologene: 21087
Ddx47
Name: DEAD box helicase 47
Synonyms: 4930588A18Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67755
Homologene: 6092
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: 5730509K17Rik, b2b1035Clo
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231214
Homologene: 18159
Nbn
Name: nibrin
Synonyms: Nbs1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 27354
HGNC: HGNC:7652
Homologene: 1858
Cntn2
Name: contactin 2
Synonyms: Tax, TAG-1, axonin, D130012K04Rik, TAG1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Robo2
Name: roundabout guidance receptor 2
Synonyms: 9430089E08Rik, D230004I22Rik, 2600013A04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268902
Homologene: 43188
Sfrp5
Name: secreted frizzled-related sequence protein 5
Synonyms: SARP3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54612
Homologene: 2268
Sun2
Name: Sad1 and UNC84 domain containing 2
Synonyms: B230369L08Rik, Unc84b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223697
Homologene: 9113
Crebrf
Name: CREB3 regulatory factor
Synonyms: A930001N09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77128
Homologene: 12672
Twf1
Name: twinfilin actin binding protein 1
Synonyms: A6, actin monomer-binding protein, twinfilin, Twinfilin-1, Ptk9
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19230
HGNC: HGNC:9620
Homologene: 48140
Tmem131
Name: transmembrane protein 131
Synonyms: CC28, 2610524E03Rik, YR-23, D1Bwg0491e, Neg, Rw1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56030
Homologene: 32428
Itgb3bp
Name: integrin beta 3 binding protein (beta3-endonexin)
Synonyms: 4930471O16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67733
HGNC: HGNC:6157
Homologene: 8617
Apc
Name: APC, WNT signaling pathway regulator
Synonyms: Min, CC1, adenomatosis polyposis coli
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11789
HGNC: HGNC:583
Homologene: 30950
Hbs1l
Name: Hbs1-like (S. cerevisiae)
Synonyms: eRFS, 2810035F15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56422
VEGA: 10
HGNC: HGNC:4834
Homologene: 68525
Dnajc27
Name: DnaJ heat shock protein family (Hsp40) member C27
Synonyms: Rabj, C330021A05Rik, Rbj
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217378
VEGA: 12
Homologene: 9558
Tmtc1
Name: transmembrane and tetratricopeptide repeat containing 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387314
Homologene: 65299
Washc5
Name: WASH complex subunit 5
Synonyms: strumpellin, E430025E21Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223593
VEGA: 15
Homologene: 8898
Zkscan17
Name: zinc finger with KRAB and SCAN domains 17
Synonyms: Nizp1, Zfp496
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268417
Homologene: 13108
Nek10
Name: NIMA (never in mitosis gene a)- related kinase 10
Synonyms: LOC238944
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 674895
Homologene: 130947
Kcp
Name: kielin/chordin-like protein
Synonyms: LOC333088, KCP, Crim2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 333088
Homologene: 87817
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: A830096D10Rik, Bai3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Tubgcp6
Name: tubulin, gamma complex component 6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328580
Homologene: 32477
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229003
Homologene: 14118
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223825
VEGA: 15
Homologene: 128807
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Stard9
Name: StAR related lipid transfer domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668880
Homologene: 130712
Grm3
Name: glutamate receptor, metabotropic 3
Synonyms: mGluR3, 0710001G23Rik, Gprc1c, mGlu3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 108069
HGNC: HGNC:4595
Homologene: 651
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 2810455B10Rik, PAR3beta, PAR3L, PAR3B, 2010002N16Rik, Als2cr19, 1810008K04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72823
Homologene: 35389
Elmo2
Name: engulfment and cell motility 2
Synonyms: 1190002F24Rik, CED-12
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 140579
Homologene: 44338
Ankrd33b
Name: ankyrin repeat domain 33B
Synonyms: 0610012A05Rik, 5730557B15Rik, 3021401C12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67434
Homologene: 12362
Atg9a
Name: autophagy related 9A
Synonyms: Apg9l1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 245860
Homologene: 34495
Wnk4
Name: WNK lysine deficient protein kinase 4
Synonyms: 2010002J11Rik, Prkwnk4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69847
Homologene: 13020
Abcb5
Name: ATP-binding cassette, sub-family B member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Rpl9
Name: ribosomal protein L9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20005
Homologene: 90855
Slco6c1
Name: solute carrier organic anion transporter family, member 6c1
Synonyms: 4933404A18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74441
Homologene: 65259
Slc6a7
Name: solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Synonyms: Prot
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240332
VEGA: 18
Homologene: 8592
Gmip
Name: Gem-interacting protein
Synonyms: 5031419I10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78816
Homologene: 9570
Ergic3
Name: ERGIC and golgi 3
Synonyms: CGI-54, NY-BR-84, 2310015B14Rik, D2Ucla1, Sdbcag84
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66366
Homologene: 5289
Npbwr1
Name: neuropeptides B/W receptor 1
Synonyms: Gpr7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226304
HGNC: HGNC:4522
Homologene: 21096
Mmrn1
Name: multimerin 1
Synonyms: 4921530G03Rik, Emilin4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70945
HGNC: HGNC:7178
Homologene: 49134
Akr1c21
Name: aldo-keto reductase family 1, member C21
Synonyms: 9430025F20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 77337
Homologene: 134114
Rhbdd1
Name: rhomboid domain containing 1
Synonyms: 4930418P06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76867
Homologene: 12659
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240776
Homologene: 16121
Zfp395
Name: zinc finger protein 395
Synonyms: LOC380912, BC027382
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380912
VEGA: 14
Homologene: 10255
Rnf19a
Name: ring finger protein 19A
Synonyms: XYbp, XY body protein, Rnf19, Dorfin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 30945
VEGA: 15
Homologene: 8501
Icosl
Name: icos ligand
Synonyms: B7h, GL50, ICOS-L, B7RP-1, GL50-B, LICOS, B7-H2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 50723
VEGA: 10
Homologene: 49412
Skint7
Name: selection and upkeep of intraepithelial T cells 7
Synonyms: C130057D23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 328505
Homologene: 106613
Vmn2r117
Name: vomeronasal 2, receptor 117
Synonyms: EG619788, V2Rp6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 619788
Homologene: 86604
Stc1
Name: stanniocalcin 1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 20855
VEGA: 14
Homologene: 2374
Or7g16
Name: olfactory receptor family 7 subfamily G member 16
Synonyms: GA_x6K02T2PVTD-12559294-12558356, MOR149-1, Olfr828
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258598
HGNC: HGNC:8466
Homologene: 133690
Olah
Name: oleoyl-ACP hydrolase
Synonyms: E230009B14Rik, Thedc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99035
Homologene: 10136
Prdm13
Name: PR domain containing 13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230025
Homologene: 11000
Or10ag56
Name: olfactory receptor family 10 subfamily AG member 56
Synonyms: GA_x6K02T2Q125-48795705-48796673, MOR264-22, Olfr1118-ps, Olfr1118
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404328
Homologene: 134077
Or1e19
Name: olfactory receptor family 1 subfamily E member 19
Synonyms: GA_x6K02T2P1NL-3586282-3585338, MOR135-2, Olfr378
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259026
Homologene: 74110
Mmp25
Name: matrix metallopeptidase 25
Synonyms: Leukolysin, MT6-MMP, F730048C11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240047
VEGA: 17
Homologene: 23375
Birc3
Name: baculoviral IAP repeat-containing 3
Synonyms: MIAP2, IAP2, Api2, cIAP2, cIAP-2, HIAP2, MIHC, RNF49
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11796
HGNC: HGNC:591
Homologene: 899
Foxf2
Name: forkhead box F2
Synonyms: FREAC2, Fkh20, LUN
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14238
HGNC: HGNC:3810
Homologene: 1115
Cyp2c67
Name: cytochrome P450, family 2, subfamily c, polypeptide 67
Synonyms: C730004C24Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 545288
Homologene: 74936
Reep2
Name: receptor accessory protein 2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225362
VEGA: 18
Homologene: 41146
Cdh22
Name: cadherin 22
Synonyms: PB-cadherin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 104010
Homologene: 23148
Pdlim2
Name: PDZ and LIM domain 2
Synonyms: mystique, SLIM, 4732462F18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 213019
Homologene: 11006
Or5d38
Name: olfactory receptor family 5 subfamily D member 38
Synonyms: GA_x6K02T2Q125-49616865-49615915, MOR174-6, Olfr1166
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258644
Homologene: 138307
4930548G14Rik
Name: RIKEN cDNA 4930548G14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75281
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 5,916,351 bp
  • T to C, chromosome 1 at 25,111,718 bp
  • T to A, chromosome 1 at 36,828,061 bp
  • A to T, chromosome 1 at 62,144,891 bp
  • T to A, chromosome 1 at 75,185,991 bp
  • A to G, chromosome 1 at 82,340,810 bp
  • G to A, chromosome 1 at 84,900,069 bp
  • A to G, chromosome 1 at 97,081,489 bp
  • C to T, chromosome 1 at 132,523,747 bp
  • A to G, chromosome 1 at 140,553,018 bp
  • A to G, chromosome 1 at 165,525,022 bp
  • A to T, chromosome 2 at 3,346,788 bp
  • A to C, chromosome 2 at 26,439,080 bp
  • T to A, chromosome 2 at 37,389,753 bp
  • T to A, chromosome 2 at 87,309,448 bp
  • A to G, chromosome 2 at 88,124,547 bp
  • T to A, chromosome 2 at 120,664,945 bp
  • C to A, chromosome 2 at 120,673,636 bp
  • T to G, chromosome 2 at 139,977,678 bp
  • A to G, chromosome 2 at 156,011,108 bp
  • T to A, chromosome 2 at 165,180,923 bp
  • T to C, chromosome 2 at 165,298,279 bp
  • C to T, chromosome 2 at 181,231,329 bp
  • A to G, chromosome 3 at 102,163,466 bp
  • T to A, chromosome 4 at 15,979,351 bp
  • T to C, chromosome 4 at 21,685,695 bp
  • A to C, chromosome 4 at 99,814,058 bp
  • T to C, chromosome 4 at 111,984,850 bp
  • T to C, chromosome 5 at 9,589,793 bp
  • G to A, chromosome 5 at 38,540,881 bp
  • G to A, chromosome 5 at 43,726,373 bp
  • C to T, chromosome 5 at 65,389,535 bp
  • G to A, chromosome 5 at 134,627,677 bp
  • T to G, chromosome 6 at 29,502,769 bp
  • A to T, chromosome 6 at 60,976,084 bp
  • ATTCTTCTTC to ATTCTTCTTCTTC, chromosome 6 at 134,921,956 bp
  • A to G, chromosome 6 at 135,018,121 bp
  • A to G, chromosome 6 at 148,284,980 bp
  • C to T, chromosome 7 at 27,366,419 bp
  • T to C, chromosome 7 at 98,129,363 bp
  • T to C, chromosome 7 at 130,731,550 bp
  • T to A, chromosome 7 at 135,698,509 bp
  • T to A, chromosome 8 at 69,814,043 bp
  • T to C, chromosome 8 at 99,033,471 bp
  • A to T, chromosome 9 at 3,430,720 bp
  • C to T, chromosome 9 at 7,860,341 bp
  • G to A, chromosome 9 at 18,815,505 bp
  • A to G, chromosome 9 at 53,240,475 bp
  • T to C, chromosome 10 at 21,364,781 bp
  • T to A, chromosome 10 at 62,640,464 bp
  • A to T, chromosome 10 at 78,071,953 bp
  • T to A, chromosome 10 at 92,884,768 bp
  • A to G, chromosome 11 at 59,492,216 bp
  • A to T, chromosome 11 at 73,425,239 bp
  • T to C, chromosome 11 at 79,537,147 bp
  • A to T, chromosome 11 at 83,004,150 bp
  • T to C, chromosome 11 at 101,263,890 bp
  • A to G, chromosome 12 at 4,097,317 bp
  • G to A, chromosome 12 at 118,877,827 bp
  • A to G, chromosome 13 at 4,574,215 bp
  • T to A, chromosome 13 at 13,806,166 bp
  • G to T, chromosome 13 at 31,626,141 bp
  • G to T, chromosome 13 at 95,513,274 bp
  • G to T, chromosome 14 at 14,840,619 bp
  • A to G, chromosome 14 at 65,388,885 bp
  • T to C, chromosome 14 at 69,031,647 bp
  • C to T, chromosome 14 at 70,164,779 bp
  • A to G, chromosome 14 at 118,130,656 bp
  • A to T, chromosome 15 at 4,917,158 bp
  • A to T, chromosome 15 at 31,297,668 bp
  • A to T, chromosome 15 at 36,241,770 bp
  • A to G, chromosome 15 at 46,625,694 bp
  • A to G, chromosome 15 at 59,341,155 bp
  • T to C, chromosome 15 at 79,726,624 bp
  • G to A, chromosome 15 at 89,104,166 bp
  • C to T, chromosome 15 at 94,585,447 bp
  • A to G, chromosome 16 at 16,048,049 bp
  • G to A, chromosome 16 at 73,933,115 bp
  • T to G, chromosome 16 at 97,038,920 bp
  • G to A, chromosome 17 at 8,929,091 bp
  • A to G, chromosome 17 at 23,477,644 bp
  • G to A, chromosome 17 at 23,640,242 bp
  • T to C, chromosome 17 at 26,742,883 bp
  • A to G, chromosome 17 at 43,628,655 bp
  • T to C, chromosome 18 at 34,310,909 bp
  • C to T, chromosome 18 at 34,845,621 bp
  • T to C, chromosome 18 at 61,001,641 bp
  • A to T, chromosome 19 at 39,643,345 bp
  • A to G, chromosome 19 at 42,198,836 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2005 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040014-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.