Strain Name:
C57BL/6J-MtgxR2024Btlr/Mmmh
Stock Number:
040033-MU
Citation ID:
RRID:MMRRC_040033-MU
Other Names:
R2024 (G1), C57BL/6J-MtgxR2024Btlr
Major Collection:

Strain Information

Ptch1
Name: patched 1
Synonyms: wig, Ptc, A230106A15Rik, Ptc1, Patched 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19206
HGNC: HGNC:9585
Homologene: 223
Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Synonyms: Src homology 2 domain-containing inositol-5-phosphatase, s-SHIP, SHIP-1, SHIP, SHIP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16331
HGNC: HGNC:6079
Homologene: 4046
Efemp1
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216616
HGNC: HGNC:3218
Homologene: 3028
Fam3c
Name: FAM3 metabolism regulating signaling molecule C
Synonyms: D6Wsu176e, Ilei, Fam3c
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27999
Homologene: 8926
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, trabeculin alpha, Acf7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Ctnnal1
Name: catenin alpha like 1
Synonyms: catenin (cadherin associated protein), alpha-like 1, Catnal1, ACRP
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Dnajc2
Name: DnaJ heat shock protein family (Hsp40) member C2
Synonyms: Zrf1, Zrf2, Mida1, MIDA1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22791
Homologene: 31656
Setd2
Name: SET domain containing 2
Synonyms: KMT3A, 4921524K10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235626
Homologene: 56493
Arid2
Name: AT-rich interaction domain 2
Synonyms: zipzap/p200, 1700124K17Rik, 4432409D24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77044
Homologene: 14601
Smchd1
Name: SMC hinge domain containing 1
Synonyms: MommeD1, 4931400A14Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74355
Homologene: 23665
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194401
Homologene: 85288
Xdh
Name: xanthine dehydrogenase
Synonyms: XO, Xox1, Xor, Xox-1, xanthine oxidase
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Psmd9
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
Synonyms: P27, Bridge-1, 1500011J20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67151
HGNC: HGNC:9567
Homologene: 2106
Chd8
Name: chromodomain helicase DNA binding protein 8
Synonyms: Duplin, 5830451P18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67772
Homologene: 72405
Ubn1
Name: ubinuclein 1
Synonyms: 2610108L02Rik, 1110029L11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 170644
VEGA: 16
Homologene: 9656
Cit
Name: citron
Synonyms: citron kinase, Cit-k, CRIK-SK, C030025P15Rik, citron-N
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Arhgap42
Name: Rho GTPase activating protein 42
Synonyms: 9030420J04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71544
Homologene: 28446
Ncbp3
Name: nuclear cap binding subunit 3
Synonyms: 1200014J11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66874
Homologene: 10231
Mms22l
Name: MMS22-like, DNA repair protein
Synonyms: F730047E07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 212377
Homologene: 18874
Lama5
Name: laminin, alpha 5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16776
HGNC: HGNC:6485
Homologene: 4060
Lig4
Name: ligase IV, DNA, ATP-dependent
Synonyms: DNA ligase IV, tiny, 5830471N16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319583
HGNC: HGNC:6601
Homologene: 1736
Hjurp
Name: Holliday junction recognition protein
Synonyms: 6430706D22Rik, A730008H23Rik, C330011F01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381280
Homologene: 10184
Tnc
Name: tenascin C
Synonyms: C130033P17Rik, TN, hexabrachion, Hxb, cytotactin, tenascin-C, TN-C
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: Dnchc2, m152Asp, m407Asp, b2b414Clo, D030010H02Rik, D330044F14Rik, 4432416O06Rik, DHC1b, DHC2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Azi2
Name: 5-azacytidine induced gene 2
Synonyms: AZ2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 27215
Homologene: 8443
Enoph1
Name: enolase-phosphatase 1
Synonyms: 2310057D15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67870
Homologene: 5790
Pom121
Name: nuclear pore membrane protein 121
Synonyms: 2610027A18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 107939
Homologene: 70878
Emc1
Name: ER membrane protein complex subunit 1
Synonyms: C230096C10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230866
Homologene: 9002
Fchsd2
Name: FCH and double SH3 domains 2
Synonyms: Sh3md3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207278
Homologene: 8887
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Rai1
Name: retinoic acid induced 1
Synonyms: Gt1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19377
HGNC: HGNC:9834
Homologene: 7508
Zfp280b
Name: zinc finger protein 280B
Synonyms: Suhw2, D10Jhu82e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64453
VEGA: 10
Homologene: 62794
Krt14
Name: keratin 14
Synonyms: Krt-1.14, K14, Krt1-14, epidermolysis bullosa simplex, Dowling-Meara, Koebner, Cytokeratin 14
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16664
HGNC: HGNC:6416
Homologene: 110439
Adamts13
Name: ADAM metallopeptidase with thrombospondin type 1 motif 13
Synonyms: LOC279028, vWF-CP mRNA for von Willebrand factor-cleaving
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Gabra5
Name: gamma-aminobutyric acid type A receptor subunit alpha 5
Synonyms: A230018I05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110886
HGNC: HGNC:4079
Homologene: 20219
AC159748.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Stxbp4
Name: syntaxin binding protein 4
Synonyms: Synip, 6030470M02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20913
Homologene: 7963
Zfp990
Name: zinc finger protein 990
Synonyms: Gm13225
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 101056073
Rhbdl2
Name: rhomboid like 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230726
Homologene: 49508
Sh3pxd2a
Name: SH3 and PX domains 2A
Synonyms: Sh3md1, 2310014D11Rik, Fish, Tks5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14218
VEGA: 19
Homologene: 7317
Flg
Name: filaggrin
Synonyms: ft, fillagrin, profilaggrin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14246
VEGA: 3
Atosa
Name: atos homolog A
Synonyms: Fam214a, 6330415I01Rik, C130047D21Rik, BC031353
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235493
VEGA: 9
Homologene: 35065
Grin2a
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Synonyms: NMDAR2A, GluRepsilon1, NR2A, GluN2A
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14811
HGNC: HGNC:4585
Homologene: 645
Dpp6
Name: dipeptidylpeptidase 6
Synonyms: In(5)6H-p, LOC384168, Rw, Dpp-6, B930011P16Rik, Peplb
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13483
HGNC: HGNC:3010
Homologene: 22560
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 665033
Homologene: 122792
Padi6
Name: peptidyl arginine deiminase, type VI
Synonyms: Padi5, ePAD, Pad6
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242726
Homologene: 17695
Vwa5a
Name: von Willebrand factor A domain containing 5A
Synonyms: Loh11cr2a, BCSC-1, 5830475I06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67776
HGNC: HGNC:6658
Homologene: 18222
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76645
Homologene: 124481
Tectb
Name: tectorin beta
Synonyms: Tctnb, [b]-tectorin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 21684
Homologene: 7568
Ndufa10
Name: NADH:ubiquinone oxidoreductase subunit A10
Synonyms: 2900053E13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67273
HGNC: HGNC:7684
Homologene: 15342
Idua
Name: iduronidase, alpha-L
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15932
HGNC: HGNC:5391
Homologene: 170
Herc6
Name: hect domain and RLD 6
Synonyms: 1700121D12Rik, CEB1, Herc5, 4930427L17Rik, 2510038N07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67138
Homologene: 70768
Col17a1
Name: collagen, type XVII, alpha 1
Synonyms: Bpag, BP180, BPAg2, Bpag2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12821
HGNC: HGNC:2194
Homologene: 7276
Kbtbd3
Name: kelch repeat and BTB (POZ) domain containing 3
Synonyms: 2200003A07Rik, Bklhd3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69149
Homologene: 12300
Pdss2
Name: prenyl (solanesyl) diphosphate synthase, subunit 2
Synonyms: PLMP, mDLP1, kd, 5430420P03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71365
Homologene: 56885
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC380729, LOC268491, Gm1564
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268491
Homologene: 19559
Tmtc4
Name: transmembrane and tetratricopeptide repeat containing 4
Synonyms: 5730419O14Rik, 4930403J22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70551
Homologene: 32796
Slc5a9
Name: solute carrier family 5 (sodium/glucose cotransporter), member 9
Synonyms: SGLT4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230612
Homologene: 17081
Tmem220
Name: transmembrane protein 220
Synonyms: A730055C05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 338369
Homologene: 18579
Nkx3-1
Name: NK3 homeobox 1
Synonyms: Nkx-3.1, Bax, NKX3.1, bagpipe, NKX3A
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18095
HGNC: HGNC:7838
Homologene: 4494
Col25a1
Name: collagen, type XXV, alpha 1
Synonyms: 2700062B08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77018
Homologene: 57111
Hmgcs2
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
Synonyms: mHS
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15360
HGNC: HGNC:5008
Homologene: 38066
Or4k49
Name: olfactory receptor family 4 subfamily K member 49
Synonyms: MOR248-8, GA_x6K02T2Q125-72715642-72716580, Olfr1299
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258886
Homologene: 17426
Stx1b
Name: syntaxin 1B
Synonyms: Stx1b2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56216
Homologene: 69375
Tox2
Name: TOX high mobility group box family member 2
Synonyms: RxHMG1, LOC269389
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269389
Homologene: 13155
Mepe
Name: matrix extracellular phosphoglycoprotein with ASARM motif (bone)
Synonyms: OF45
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 94111
Homologene: 10623
Gfi1
Name: growth factor independent 1 transcription repressor
Synonyms: Gfi-1, Pal-1, Pal1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14581
HGNC: HGNC:4237
Homologene: 3854
Slfn9
Name: schlafen 9
Synonyms: 9830137M10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237886
Homologene: 45432
Gm6741
Name: predicted gene 6741
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627235
VEGA: 17
AC127247.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Sgpp2
Name: sphingosine-1-phosphate phosphatase 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 433323
Homologene: 51848
Arpc4
Name: actin related protein 2/3 complex, subunit 4
Synonyms: 5330419I20Rik, p20-Arc
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68089
HGNC: HGNC:707
Homologene: 4177
Rnase2a
Name: ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)
Synonyms: Ear11
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 93726
VEGA: 14
Homologene: 121614
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 78,417,220 bp
  • T to A, chromosome 1 at 87,695,350 bp
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • A to G, chromosome 1 at 92,439,892 bp
  • T to C, chromosome 2 at 26,992,871 bp
  • T to A, chromosome 2 at 111,664,823 bp
  • T to C, chromosome 2 at 163,276,220 bp
  • T to C, chromosome 2 at 180,179,130 bp
  • C to T, chromosome 3 at 92,806,502 bp
  • T to A, chromosome 3 at 93,279,415 bp
  • T to C, chromosome 3 at 98,299,214 bp
  • A to T, chromosome 3 at 130,476,362 bp
  • A to G, chromosome 4 at 24,588,365 bp
  • A to G, chromosome 4 at 56,848,003 bp
  • A to G, chromosome 4 at 63,964,621 bp
  • G to A, chromosome 4 at 111,890,531 bp
  • C to T, chromosome 4 at 123,371,918 bp
  • A to T, chromosome 4 at 123,826,872 bp
  • G to A, chromosome 4 at 139,360,946 bp
  • T to G, chromosome 4 at 140,728,968 bp
  • A to C, chromosome 4 at 145,537,404 bp
  • A to C, chromosome 5 at 21,776,790 bp
  • A to G, chromosome 5 at 27,709,459 bp
  • T to A, chromosome 5 at 100,063,888 bp
  • T to C, chromosome 5 at 104,327,091 bp
  • T to C, chromosome 5 at 107,723,220 bp
  • C to T, chromosome 5 at 108,680,734 bp
  • T to C, chromosome 5 at 115,947,924 bp
  • T to C, chromosome 5 at 116,005,840 bp
  • T to G, chromosome 5 at 121,281,918 bp
  • T to C, chromosome 5 at 123,241,862 bp
  • T to C, chromosome 5 at 135,381,550 bp
  • T to C, chromosome 6 at 22,329,593 bp
  • C to T, chromosome 6 at 57,583,332 bp
  • C to A, chromosome 6 at 113,388,768 bp
  • A to T, chromosome 6 at 121,031,136 bp
  • G to A, chromosome 7 at 57,488,950 bp
  • A to C, chromosome 7 at 101,198,533 bp
  • A to T, chromosome 7 at 127,815,403 bp
  • A to T, chromosome 8 at 9,972,436 bp
  • A to G, chromosome 8 at 117,019,533 bp
  • C to T, chromosome 9 at 4,317,075 bp
  • A to G, chromosome 9 at 7,129,062 bp
  • T to C, chromosome 9 at 9,005,903 bp
  • T to C, chromosome 9 at 38,736,061 bp
  • A to G, chromosome 9 at 75,010,390 bp
  • G to T, chromosome 9 at 105,936,994 bp
  • T to C, chromosome 9 at 110,549,133 bp
  • C to T, chromosome 9 at 118,049,322 bp
  • A to G, chromosome 10 at 5,368,180 bp
  • A to T, chromosome 10 at 43,393,875 bp
  • T to C, chromosome 10 at 76,038,494 bp
  • A to T, chromosome 11 at 28,914,696 bp
  • T to C, chromosome 11 at 60,185,589 bp
  • T to C, chromosome 11 at 67,034,153 bp
  • T to A, chromosome 11 at 73,053,520 bp
  • A to G, chromosome 11 at 82,981,681 bp
  • T to C, chromosome 11 at 90,575,343 bp
  • C to T, chromosome 11 at 100,207,218 bp
  • C to T, chromosome 11 at 102,675,358 bp
  • T to G, chromosome 13 at 63,524,959 bp
  • T to A, chromosome 14 at 51,255,788 bp
  • T to C, chromosome 14 at 52,231,493 bp
  • T to C, chromosome 14 at 69,190,817 bp
  • T to C, chromosome 14 at 122,921,265 bp
  • A to T, chromosome 15 at 8,157,760 bp
  • A to G, chromosome 15 at 96,361,799 bp
  • T to G, chromosome 16 at 5,064,623 bp
  • T to C, chromosome 16 at 9,644,243 bp
  • T to A, chromosome 17 at 71,370,928 bp
  • A to G, chromosome 17 at 73,921,305 bp
  • G to A, chromosome 17 at 91,236,881 bp
  • T to C, chromosome 19 at 47,267,264 bp
  • T to A, chromosome 19 at 47,650,746 bp
  • T to C, chromosome 19 at 55,181,929 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2024 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040033-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.