Strain Name:
C57BL/6J-MtgxR2027Btlr/Mmmh
Stock Number:
040035-MU
Citation ID:
RRID:MMRRC_040035-MU
Other Names:
R2027 (G1), C57BL/6J-MtgxR2027Btlr
Major Collection:

Gene Information

Ptch1
Name: patched 1
Synonyms: Ptc1, Patched 1, A230106A15Rik, wig, Ptc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19206
HGNC: HGNC:9585
Homologene: 223
Rc3h1
Name: RING CCCH (C3H) domains 1
Synonyms: roquin, 5730557L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381305
Homologene: 19036
Efemp1
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216616
HGNC: HGNC:3218
Homologene: 3028
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Slc25a13
Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
Synonyms: citrin, Ctrn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 50799
Homologene: 22800
Pik3c2a
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Synonyms: PI3KC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18704
HGNC: HGNC:8971
Homologene: 20581
Dido1
Name: death inducer-obliterator 1
Synonyms: 6720461J16Rik, D130048F08Rik, dido, DIO-1, Datf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 23856
HGNC: HGNC:2680
Homologene: 34139
Gan
Name: giant axonal neuropathy
Synonyms: gigaxonin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 209239
HGNC: HGNC:4137
Homologene: 32523
Nckap1
Name: NCK-associated protein 1
Synonyms: Hem-2, Nap1, H19, Hem2, mh19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50884
HGNC: HGNC:7666
Homologene: 8384
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: IP3R1, opt, Pcp1, wblo, Pcp-1, Ip3r, P400, InsP3R type I, Itpr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Cap1
Name: CAP, adenylate cyclase-associated protein 1 (yeast)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12331
Homologene: 74572
Arhgap42
Name: Rho GTPase activating protein 42
Synonyms: 9030420J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71544
Homologene: 28446
Dpp8
Name: dipeptidylpeptidase 8
Synonyms: 4932434F09Rik, 2310004I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74388
VEGA: 9
Homologene: 57098
Camsap1
Name: calmodulin regulated spectrin-associated protein 1
Synonyms: 9530003A05Rik, PRO2405
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227634
Homologene: 19202
Bag1
Name: BCL2-associated athanogene 1
Synonyms: Rap46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12017
HGNC: HGNC:937
Homologene: 3190
Otof
Name: otoferlin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 83762
HGNC: HGNC:8515
Homologene: 12892
Dbp
Name: D site albumin promoter binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13170
HGNC: HGNC:2697
Homologene: 1035
Cuzd1
Name: CUB and zona pellucida-like domains 1
Synonyms: Itmap1, UTCZP, ERG-1, UO-44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16433
Homologene: 7389
Dsg2
Name: desmoglein 2
Synonyms: D18Ertd293e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13511
HGNC: HGNC:3049
Homologene: 1464
Rabgef1
Name: RAB guanine nucleotide exchange factor (GEF) 1
Synonyms: Ras negative regulator Rabex-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56715
Homologene: 8720
Caprin2
Name: caprin family member 2
Synonyms: RNG140, Eeg1, C1qdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232560
Homologene: 11393
Dhps
Name: deoxyhypusine synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 330817
HGNC: HGNC:2869
Homologene: 1453
Slc44a3
Name: solute carrier family 44, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213603
Homologene: 64830
Kxd1
Name: KxDL motif containing 1
Synonyms: 2810422J05Rik, 0610030B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 75620
Homologene: 11447
Zfp280b
Name: zinc finger protein 280B
Synonyms: D10Jhu82e, Suhw2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 64453
VEGA: 10
Homologene: 62794
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Ccn4
Name: cellular communication network factor 4
Synonyms: CCN4, Wisp1, Elm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 22402
Homologene: 2883
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Olfr1413
Name: olfactory receptor 1413
Synonyms: MOR208-1, GA_x6K02T2R7CC-81180849-81179878
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 259039
Homologene: 128165
Apoa4
Name: apolipoprotein A-IV
Synonyms: Apoa-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11808
HGNC: HGNC:602
Homologene: 47927
Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Synonyms: smMHC, SM2, SM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17880
VEGA: 16
HGNC: HGNC:7569
Homologene: 128512
Vmn2r100
Name: vomeronasal 2, receptor 100
Synonyms: EG627537
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627537
Homologene: 129750
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mgr1, Mass1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Cabp2
Name: calcium binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 29866
HGNC: HGNC:1385
Homologene: 8487
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Sclt1
Name: sodium channel and clathrin linker 1
Synonyms: Tg(ACTB-sb10)1Dla, 2610207F23Rik, CAGGS-SB10, 4931421F20Rik, Tg(CAG-sb10)1Dla
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67161
Homologene: 27031
Peli2
Name: pellino 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 93834
VEGA: 14
HGNC: HGNC:8828
Homologene: 41431
Abca8b
Name: ATP-binding cassette, sub-family A (ABC1), member 8b
Synonyms: Abca8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 27404
HGNC: HGNC:38
Homologene: 56029
Syne4
Name: spectrin repeat containing, nuclear envelope family member 4
Synonyms: 0610012K07Rik, nesprin-4, AI428936
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233066
Homologene: 17716
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 333315
Homologene: 35388
Olfr1025-ps1
Name: olfactory receptor 1025, pseudogene 1
Synonyms: MOR196-6_p, GA_x6K02T2Q125-47397266-47398205, MOR196-5P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258083
Aatk
Name: apoptosis-associated tyrosine kinase
Synonyms: AATYK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11302
HGNC: HGNC:21
Homologene: 74861
Pkn1
Name: protein kinase N1
Synonyms: Pkn, F730027O18Rik, PAK1, Stk3, Prkcl1, PRK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320795
HGNC: HGNC:9405
Homologene: 48130
Cyp26b1
Name: cytochrome P450, family 26, subfamily b, polypeptide 1
Synonyms: retinoic acid B1, CP26, P450RAI-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232174
Homologene: 23179
Faxc
Name: failed axon connections homolog
Synonyms: 6230409E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76132
Homologene: 32781
Vmn1r87
Name: vomeronasal 1 receptor 87
Synonyms: V1rk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171261
Homologene: 134023
Prr5
Name: proline rich 5 (renal)
Synonyms: Protor-1, C030017C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 109270
Homologene: 17132
Kbtbd3
Name: kelch repeat and BTB (POZ) domain containing 3
Synonyms: 2200003A07Rik, Bklhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69149
Homologene: 12300
Uqcrc1
Name: ubiquinol-cytochrome c reductase core protein 1
Synonyms: 1110032G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22273
Homologene: 2525
Tmtc4
Name: transmembrane and tetratricopeptide repeat containing 4
Synonyms: 5730419O14Rik, 4930403J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 70551
Homologene: 32796
Hook3
Name: hook microtubule tethering protein 3
Synonyms: E330005F07Rik, 5830454D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320191
Homologene: 13022
Vmn2r97
Name: vomeronasal 2, receptor 97
Synonyms: EG627367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627367
Homologene: 115024
Tmem161a
Name: transmembrane protein 161A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234371
Homologene: 9853
Pramel5
Name: preferentially expressed antigen in melanoma like 5
Synonyms: OTTMUSG00000010540
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 384077
Homologene: 133722
Fam92a
Name: family with sequence similarity 92, member A
Synonyms: 6720467C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68099
Homologene: 12234
Olfr731
Name: olfactory receptor 731
Synonyms: MOR246-5, GA_x6K02T2PMLR-5936117-5935137
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258360
Homologene: 84579
Gnl1
Name: guanine nucleotide binding protein-like 1
Synonyms: Gna-rs1, Gnal1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14670
HGNC: HGNC:4413
Homologene: 3862
Olfr1107
Name: olfactory receptor 1107
Synonyms: MOR172-2, GA_x6K02T2Q125-48565383-48564445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258841
Homologene: 131138
1700014D04Rik
Name: RIKEN cDNA 1700014D04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 102638268
Homologene: 140986
Bcl2a1d
Name: B cell leukemia/lymphoma 2 related protein A1d
Synonyms: A1-d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12047
HGNC: HGNC:991
Homologene: 2988
Gm11487
Name: predicted gene 11487
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 433719
Homologene: 128423
Olfr825
Name: olfactory receptor 825
Synonyms: MOR210-1, GA_x6K02T2PULF-11834065-11833103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258672
Homologene: 121503
Mepe
Name: matrix extracellular phosphoglycoprotein with ASARM motif (bone)
Synonyms: OF45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 94111
Homologene: 10623
Slc7a9
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
Synonyms: CSNU3, bo, +AT, bo, + amino acid transporter
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 30962
Homologene: 56668
Rpl7a-ps5
Name: ribosomal protein L7A, pseudogene 5
Synonyms: Gm16375
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 674419
VEGA: 17
Slc22a17
Name: solute carrier family 22 (organic cation transporter), member 17
Synonyms: 1700094C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 59049
VEGA: 14
Homologene: 10684
Olfr582
Name: olfactory receptor 582
Synonyms: MOR30-3, GA_x6K02T2PBJ9-5752857-5753801
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259055
Homologene: 73943
Zfp579
Name: zinc finger protein 579
Synonyms: 1110003A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68490
Homologene: 17629
Yif1a
Name: Yip1 interacting factor homolog A (S. cerevisiae)
Synonyms: 5330422J23Rik, Yif1p, 54TM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 68090
VEGA: 19
Homologene: 56295
Tmem240
Name: transmembrane protein 240
Synonyms: Gm5151
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381582
Homologene: 19885
Gm6658
Name: predicted gene 6658
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Ccdc107
Name: coiled-coil domain containing 107
Synonyms: 1110032O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 622404
Homologene: 52163
A4gnt
Name: alpha-1,4-N-acetylglucosaminyltransferase
Synonyms: LOC333424, alpha4GnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 333424
Homologene: 87446
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 92,573,767 bp
  • C to T, chromosome 1 at 160,954,937 bp
  • A to G, chromosome 2 at 25,938,526 bp
  • A to T, chromosome 2 at 80,535,518 bp
  • A to C, chromosome 2 at 85,918,770 bp
  • T to A, chromosome 2 at 87,071,553 bp
  • A to T, chromosome 2 at 180,689,181 bp
  • T to A, chromosome 3 at 37,047,961 bp
  • G to A, chromosome 3 at 41,730,888 bp
  • T to C, chromosome 3 at 121,463,410 bp
  • T to A, chromosome 4 at 12,171,216 bp
  • T to C, chromosome 4 at 21,958,439 bp
  • T to C, chromosome 4 at 40,941,652 bp
  • T to C, chromosome 4 at 43,495,874 bp
  • A to G, chromosome 4 at 73,403,058 bp
  • T to G, chromosome 4 at 122,862,893 bp
  • C to T, chromosome 4 at 123,371,918 bp
  • A to G, chromosome 4 at 144,271,704 bp
  • A to G, chromosome 4 at 155,735,435 bp
  • T to C, chromosome 5 at 30,421,014 bp
  • T to C, chromosome 5 at 104,327,091 bp
  • A to G, chromosome 5 at 130,208,779 bp
  • A to G, chromosome 6 at 6,073,487 bp
  • A to G, chromosome 6 at 84,584,483 bp
  • C to A, chromosome 6 at 108,386,853 bp
  • A to G, chromosome 6 at 148,877,887 bp
  • C to A, chromosome 7 at 4,993,521 bp
  • G to A, chromosome 7 at 13,131,896 bp
  • C to A, chromosome 7 at 30,315,413 bp
  • G to A, chromosome 7 at 35,454,137 bp
  • C to A, chromosome 7 at 45,708,276 bp
  • A to T, chromosome 7 at 103,041,524 bp
  • T to C, chromosome 7 at 116,350,822 bp
  • T to C, chromosome 7 at 131,320,091 bp
  • T to C, chromosome 8 at 26,038,098 bp
  • T to A, chromosome 8 at 70,177,520 bp
  • A to G, chromosome 8 at 70,515,450 bp
  • G to T, chromosome 8 at 80,695,337 bp
  • A to G, chromosome 8 at 83,671,378 bp
  • A to T, chromosome 8 at 85,072,611 bp
  • A to G, chromosome 8 at 90,907,991 bp
  • T to C, chromosome 8 at 117,187,499 bp
  • C to T, chromosome 9 at 4,317,075 bp
  • T to C, chromosome 9 at 9,005,903 bp
  • G to A, chromosome 9 at 46,243,000 bp
  • T to A, chromosome 9 at 65,078,774 bp
  • T to C, chromosome 9 at 79,645,793 bp
  • A to T, chromosome 9 at 88,731,385 bp
  • T to C, chromosome 9 at 99,620,201 bp
  • G to A, chromosome 9 at 108,947,015 bp
  • T to C, chromosome 10 at 76,038,494 bp
  • A to G, chromosome 10 at 130,162,735 bp
  • A to T, chromosome 11 at 28,914,696 bp
  • T to G, chromosome 11 at 65,955,338 bp
  • A to T, chromosome 11 at 109,957,049 bp
  • A to G, chromosome 11 at 120,009,317 bp
  • A to G, chromosome 13 at 59,742,587 bp
  • T to G, chromosome 13 at 63,524,959 bp
  • C to T, chromosome 13 at 81,595,182 bp
  • C to T, chromosome 14 at 33,956,018 bp
  • G to A, chromosome 14 at 48,256,145 bp
  • A to G, chromosome 14 at 50,237,949 bp
  • A to G, chromosome 14 at 54,908,086 bp
  • T to C, chromosome 14 at 122,921,265 bp
  • A to T, chromosome 15 at 8,157,760 bp
  • A to G, chromosome 15 at 66,917,409 bp
  • A to T, chromosome 15 at 84,701,379 bp
  • A to G, chromosome 16 at 14,232,668 bp
  • T to A, chromosome 17 at 18,929,682 bp
  • A to T, chromosome 17 at 19,522,072 bp
  • A to G, chromosome 17 at 35,982,958 bp
  • G to T, chromosome 17 at 57,839,095 bp
  • A to G, chromosome 18 at 20,583,004 bp
  • A to G, chromosome 18 at 31,984,960 bp
  • T to A, chromosome 19 at 4,087,126 bp
  • A to T, chromosome 19 at 5,089,872 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2027 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040035-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.