Strain Name:
C57BL/6J-MtgxR2030Btlr/Mmmh
Stock Number:
040037-MU
Citation ID:
RRID:MMRRC_040037-MU
Other Names:
R2030 (G1), C57BL/6J-MtgxR2030Btlr
Major Collection:

Gene Information

Snap25
Name: synaptosomal-associated protein 25
Synonyms: sp, SNAP-25, GENA 70, Bdr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20614
Homologene: 13311
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Cdk7
Name: cyclin-dependent kinase 7
Synonyms: CRK4 PK (CDC2-related-kinase-4 protein kinase), Crk4, Cdkn7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 12572
VEGA: 13
HGNC: HGNC:1778
Homologene: 1363
Ak2
Name: adenylate kinase 2
Synonyms: Ak-2, D4Ertd220e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11637
HGNC: HGNC:362
Homologene: 1227
Prdm2
Name: PR domain containing 2, with ZNF domain
Synonyms: Riz, Riz1, LOC381568, E330024L24Rik, 4833427P12Rik, KMT8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 110593
HGNC: HGNC:9347
Homologene: 40822
Zfat
Name: zinc finger and AT hook domain containing
Synonyms: LOC380993, Zfp406, Zfat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 380993
Homologene: 16829
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, D15F32S1h, D7H15F37S1, rjs, jdf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, 6530403D07Rik, D2Ertd145e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Ncapd2
Name: non-SMC condensin I complex, subunit D2
Synonyms: CNAP1, CAP-D2, 2810406C15Rik, 2810465G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68298
Homologene: 6497
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: TFIIIB150, TFIIIB90, TAF3B1, TFC5, Tfnr, G630013P12Rik, B130055N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544971
Homologene: 34582
Zfp442
Name: zinc finger protein 442
Synonyms: OTTMUSG00000015730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668923
Homologene: 136215
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Fuca2
Name: fucosidase, alpha-L- 2, plasma
Synonyms: 5530401P20Rik, 0610025O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66848
HGNC: HGNC:4008
Homologene: 119
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4921518A06Rik, 4933421G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Dnaaf10
Name: dynein axonemal assembly factor 10
Synonyms: Wdr92
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103784
Homologene: 16321
Shisa2
Name: shisa family member 2
Synonyms: 9430059P22Rik, shisa, mShisa, Tmem46, MAd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219134
VEGA: 14
Homologene: 17078
Tsc2
Name: TSC complex subunit 2
Synonyms: tuberin, Nafld, tuberous sclerosis 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22084
VEGA: 17
Homologene: 462
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: extraocular myosin, EO Myosin, MyHC-eo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Kcp
Name: kielin/chordin-like protein
Synonyms: LOC333088, KCP, Crim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 333088
Homologene: 87817
Adtrp
Name: androgen dependent TFPI regulating protein
Synonyms: 9530008L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109254
Homologene: 13107
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268933
Homologene: 6870
Ccser1
Name: coiled-coil serine rich 1
Synonyms: 6230405M12Rik, C130092O11Rik, Fam190a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232035
Homologene: 28086
Mrgprb1
Name: MAS-related GPR, member B1
Synonyms: MrgB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233231
Homologene: 24986
1700022I11Rik
Name: RIKEN cDNA 1700022I11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67317
Homologene: 52406
Nlrp12
Name: NLR family, pyrin domain containing 12
Synonyms: Nalp12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 378425
Homologene: 16972
Or7e169
Name: olfactory receptor family 7 subfamily E member 169
Synonyms: GA_x6K02T2PVTD-13586614-13585661, MOR146-2, Olfr860
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258521
Homologene: 134093
Or4a72
Name: olfactory receptor family 4 subfamily A member 72
Synonyms: GA_x6K02T2Q125-51020951-51020028, MOR231-12, Olfr1245
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258784
Homologene: 121560
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81877
Homologene: 49589
Mre11a
Name: MRE11A homolog A, double strand break repair nuclease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17535
HGNC: HGNC:7230
Homologene: 4083
Htra4
Name: HtrA serine peptidase 4
Synonyms: B430206E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330723
Homologene: 17801
Eif2b1
Name: eukaryotic translation initiation factor 2B, subunit 1 (alpha)
Synonyms: EIF2BA, EIF2B, 26kDa, D5Ertd406e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 209354
HGNC: HGNC:3257
Homologene: 1080
Gm4787
Name: predicted gene 4787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 214321
Homologene: 86950
Pklr
Name: pyruvate kinase liver and red blood cell
Synonyms: Pk1, Pk-1, R-PK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18770
HGNC: HGNC:9020
Homologene: 37286
Atp13a4
Name: ATPase type 13A4
Synonyms: 4631413J11Rik, 9330174J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224079
Homologene: 75330
CK137956
Name: cDNA sequence CK137956
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 635169
Homologene: 57187
Tas2r137
Name: taste receptor, type 2, member 137
Synonyms: mt2r41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 574417
Homologene: 23231
Tpte
Name: transmembrane phosphatase with tensin homology
Synonyms: Pten2, Vsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234129
Homologene: 50411
Disp3
Name: dispatched RND transporter family member 3
Synonyms: G630052C06Rik, Ptchd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242748
Homologene: 25712
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67607
Homologene: 137363
Tas2r140
Name: taste receptor, type 2, member 140
Synonyms: TRB3, TRB5, mTRB3, Tas2r40, T2R40, mt2r64, Tas2r13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387616
Homologene: 87013
Zc3h6
Name: zinc finger CCCH type containing 6
Synonyms: 4631426G04Rik, 4833425H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78751
Homologene: 35328
Mindy4
Name: MINDY lysine 48 deubiquitinase 4
Synonyms: LOC384387, C330043M08Rik, Fam188b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330323
Homologene: 49991
Fbxw5
Name: F-box and WD-40 domain protein 5
Synonyms: Fbw5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 30839
Homologene: 8496
Epx
Name: eosinophil peroxidase
Synonyms: EPO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13861
HGNC: HGNC:3423
Homologene: 20144
Kcnd3
Name: potassium voltage-gated channel, Shal-related family, member 3
Synonyms: potassium channel Kv4.3M, potassium channel Kv4.3L, Kv4.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56543
HGNC: HGNC:6239
Homologene: 21036
Ryk
Name: receptor-like tyrosine kinase
Synonyms: Vik, ERK-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20187
Homologene: 68287
Fmo4
Name: flavin containing monooxygenase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226564
HGNC: HGNC:3772
Homologene: 68219
Snx31
Name: sorting nexin 31
Synonyms: 4631426E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66696
Homologene: 23551
Dbndd2
Name: dysbindin (dystrobrevin binding protein 1) domain containing 2
Synonyms: 2900022J10Rik, 1110017A21Rik, D2Bwg0891e, NKIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 52840
Homologene: 12276
Thumpd2
Name: THUMP domain containing 2
Synonyms: 2810025A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72167
VEGA: 17
Homologene: 11898
Gpat3
Name: glycerol-3-phosphate acyltransferase 3
Synonyms: A230097K15Rik, 4933407I02Rik, Agpat9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231510
Homologene: 13099
Or3a1c
Name: olfactory receptor family 3 subfamily A member 1C
Synonyms: GA_x6K02T2P1NL-4307199-4308146, MOR255-4, Olfr402
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258703
HGNC: HGNC:8282
Homologene: 1915
Lrrc52
Name: leucine rich repeat containing 52
Synonyms: 4930413P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240899
Homologene: 35430
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 162,794,172 bp
  • T to C, chromosome 1 at 167,466,459 bp
  • G to T, chromosome 2 at 25,504,798 bp
  • T to A, chromosome 2 at 52,092,346 bp
  • C to T, chromosome 2 at 76,872,933 bp
  • C to T, chromosome 2 at 89,575,214 bp
  • T to A, chromosome 2 at 119,921,511 bp
  • T to C, chromosome 2 at 129,006,086 bp
  • T to G, chromosome 2 at 136,770,053 bp
  • A to T, chromosome 2 at 150,408,122 bp
  • A to G, chromosome 2 at 164,488,643 bp
  • A to G, chromosome 3 at 89,143,238 bp
  • A to G, chromosome 3 at 105,459,537 bp
  • C to T, chromosome 4 at 42,974,131 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • A to G, chromosome 4 at 127,951,387 bp
  • A to G, chromosome 4 at 129,008,220 bp
  • T to C, chromosome 4 at 143,132,764 bp
  • A to T, chromosome 4 at 148,259,966 bp
  • G to A, chromosome 5 at 100,897,821 bp
  • A to G, chromosome 5 at 124,576,925 bp
  • G to A, chromosome 6 at 29,489,072 bp
  • A to G, chromosome 6 at 40,492,220 bp
  • A to G, chromosome 6 at 55,211,262 bp
  • C to T, chromosome 6 at 61,311,563 bp
  • A to G, chromosome 6 at 125,176,715 bp
  • T to C, chromosome 6 at 133,055,250 bp
  • T to A, chromosome 7 at 3,228,417 bp
  • A to G, chromosome 7 at 41,649,560 bp
  • A to T, chromosome 7 at 48,447,328 bp
  • A to G, chromosome 7 at 56,184,373 bp
  • A to C, chromosome 8 at 22,345,885 bp
  • T to A, chromosome 8 at 25,033,577 bp
  • A to T, chromosome 9 at 14,795,805 bp
  • A to G, chromosome 9 at 19,846,413 bp
  • T to A, chromosome 9 at 102,881,656 bp
  • A to G, chromosome 10 at 13,506,774 bp
  • A to T, chromosome 11 at 17,229,832 bp
  • T to G, chromosome 11 at 67,350,238 bp
  • T to A, chromosome 11 at 74,155,943 bp
  • T to C, chromosome 11 at 87,864,824 bp
  • C to T, chromosome 12 at 81,378,770 bp
  • C to T, chromosome 13 at 41,828,259 bp
  • A to T, chromosome 13 at 100,061,189 bp
  • A to G, chromosome 13 at 100,722,674 bp
  • A to T, chromosome 14 at 59,629,685 bp
  • A to T, chromosome 15 at 8,350,287 bp
  • G to A, chromosome 15 at 36,525,702 bp
  • A to G, chromosome 15 at 68,118,934 bp
  • A to T, chromosome 16 at 29,422,684 bp
  • C to T, chromosome 17 at 24,623,470 bp
  • A to G, chromosome 17 at 25,826,043 bp
  • A to T, chromosome 17 at 34,718,469 bp
  • G to A, chromosome 17 at 81,064,958 bp
  • A to G, chromosome 19 at 18,854,265 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2030 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040037-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.