Strain Name:
C57BL/6J-MtgxR2032Btlr/Mmmh
Stock Number:
040039-MU
Citation ID:
RRID:MMRRC_040039-MU
Other Names:
R2032 (G1), C57BL/6J-MtgxR2032Btlr
Major Collection:

Gene Information

Fam110b
Name: family with sequence similarity 110, member B
Synonyms: 1700012H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242297
Homologene: 17518
Slc29a1
Name: solute carrier family 29 (nucleoside transporters), member 1
Synonyms: ENT1, NBMPR-sensitive equilibrative nucleoside transporter, 1200014D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 63959
Homologene: 37985
Hmmr
Name: hyaluronan mediated motility receptor (RHAMM)
Synonyms: CD168, Rhamm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15366
HGNC: HGNC:5012
Homologene: 8271
Akap12
Name: A kinase (PRKA) anchor protein (gravin) 12
Synonyms: SSeCKS, Tsga12, Srcs5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 83397
VEGA: 10
HGNC: HGNC:370
Homologene: 3740
Atxn3
Name: ataxin 3
Synonyms: Sca3, MJD1, 2210008M02Rik, ataxin-3, Mjd, Atx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 110616
HGNC: HGNC:7106
Homologene: 3658
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: VPARP, VAULT3, p193, PH5P, E230037B21Rik, Adprtl1, C030027K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Nop14
Name: NOP14 nucleolar protein
Synonyms: 2610033H07Rik, Nol14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75416
Homologene: 41773
Ccdc138
Name: coiled-coil domain containing 138
Synonyms: 6230424H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76138
VEGA: 10
Homologene: 44912
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Bmp2
Name: bone morphogenetic protein 2
Synonyms: Bmp2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12156
HGNC: HGNC:1069
Homologene: 926
Syt13
Name: synaptotagmin XIII
Synonyms: 5730409J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 80976
Homologene: 10823
Dolpp1
Name: dolichyl pyrophosphate phosphatase 1
Synonyms: LSFR2, 0610011H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57170
Homologene: 10663
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72205
Homologene: 8125
Atl2
Name: atlastin GTPase 2
Synonyms: Aip-2, 2010110I21Rik, Arl6ip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56298
VEGA: 17
Homologene: 56949
Dennd6a
Name: DENN/MADD domain containing 6A
Synonyms: A630054L15Rik, Fam116a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211922
Homologene: 13503
Akap11
Name: A kinase (PRKA) anchor protein 11
Synonyms: 6330501D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219181
HGNC: HGNC:369
Homologene: 8279
Trpv1
Name: transient receptor potential cation channel, subfamily V, member 1
Synonyms: capsaicin receptor, VR-1, OTRPC1, Vr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 193034
Homologene: 12920
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72685
Homologene: 8865
Cep164
Name: centrosomal protein 164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214552
Homologene: 51110
Fgf10
Name: fibroblast growth factor 10
Synonyms: FGF-10, AEY17, Gsfaey17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14165
HGNC: HGNC:3666
Homologene: 3284
Abca3
Name: ATP-binding cassette, sub-family A (ABC1), member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71395
Homologene: 138430
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 545030
Homologene: 83473
Vmn1r78
Name: vomeronasal 1 receptor 78
Synonyms: V1rg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171242
Homologene: 74316
Gm8251
Name: predicted gene 8251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Pold2
Name: polymerase (DNA directed), delta 2, regulatory subunit
Synonyms: p50, po1D2, 50kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18972
HGNC: HGNC:9176
Homologene: 4538
Tram2
Name: translocating chain-associating membrane protein 2
Synonyms: C330003D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 170829
Homologene: 8183
Ankrd36
Name: ankyrin repeat domain 36
Synonyms: 1700012M14Rik, GC3, 1700008J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76389
Homologene: 137366
Sik2
Name: salt inducible kinase 2
Synonyms: G630080D20Rik, Snf1lk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235344
Homologene: 22875
Nt5dc1
Name: 5'-nucleotidase domain containing 1
Synonyms: 6030401B09Rik, Nt5c2l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 319638
Homologene: 16281
CK137956
Name: cDNA sequence CK137956
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 635169
Homologene: 57187
Cfhr4
Name: complement factor H-related 4
Synonyms: Gm4788
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214403
Serpina3m
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3M
Synonyms: contrapsin-like, Spi-2rs1, Spi-2l, Spi2-rs1, MMSPi2.4, Spi2.4, MMCM7, 3e46, antitrypsin, alpha-1 antiproteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20717
HGNC: HGNC:16
Homologene: 111129
Olfr33
Name: olfactory receptor 33
Synonyms: MTPCR33, MOR11-2, GA_x6K02T2PBJ9-5431102-5430146
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18332
Homologene: 81534
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: 5031409J19Rik, Gpr110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77596
Homologene: 124643
Fap
Name: fibroblast activation protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14089
HGNC: HGNC:3590
Homologene: 48282
Hif3a
Name: hypoxia inducible factor 3, alpha subunit
Synonyms: MOP7, bHLHe17, Nepas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53417
Homologene: 9646
Tmem237
Name: transmembrane protein 237
Synonyms: LOC381259, Als2cr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381259
Homologene: 17570
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Op1, Mater, Nalp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23968
Homologene: 65105
D830046C22Rik
Name: RIKEN cDNA D830046C22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Pyroxd2
Name: pyridine nucleotide-disulphide oxidoreductase domain 2
Synonyms: 3830409H07Rik, 4833409A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74580
VEGA: 19
Homologene: 13097
Recql
Name: RecQ protein-like
Synonyms: RecQ1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19691
HGNC: HGNC:9948
Homologene: 56279
Acox2
Name: acyl-Coenzyme A oxidase 2, branched chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 93732
HGNC: HGNC:120
Homologene: 74473
Ankrd44
Name: ankyrin repeat domain 44
Synonyms: E130014H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329154
Homologene: 27547
Prr36
Name: proline rich 36
Synonyms: BC068157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73072
Homologene: 136398
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Gm6583
Name: predicted gene 6583
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 625424
Homologene: 116059
Olfr1417
Name: olfactory receptor 1417
Synonyms: GA_x6K02T2RE5P-2172809-2171862, MOR266-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258938
Homologene: 27304
Slc27a3
Name: solute carrier family 27 (fatty acid transporter), member 3
Synonyms: fatty acid transport protein 3, FATP3, Acsvl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26568
Homologene: 11529
Ugt2b34
Name: UDP glucuronosyltransferase 2 family, polypeptide B34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100727
Homologene: 117389
Zpbp2
Name: zona pellucida binding protein 2
Synonyms: 1700017D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69376
Homologene: 18892
Mas1
Name: MAS1 oncogene
Synonyms: Mas-1, Mas receptor, MasR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17171
HGNC: HGNC:6899
Homologene: 1782
Col23a1
Name: collagen, type XXIII, alpha 1
Synonyms: 2810458L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237759
Homologene: 72101
Pate12
Name: prostate and testis expressed 12
Synonyms: Gm7257
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 639025
Homologene: 86450
Olfr57
Name: olfactory receptor 57
Synonyms: IF12, MOR139-3, GA_x6K02T2QGN0-2777431-2776472
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18357
HGNC: HGNC:8368
Homologene: 133620
Gm3443
Name: predicted gene 3443
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Ttc33
Name: tetratricopeptide repeat domain 33
Synonyms: 2410099M07Rik, 2900001O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67515
Homologene: 8226
Vmn1r224
Name: vomeronasal 1 receptor 224
Synonyms: Gm7673
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 665525
Homologene: 85978
Echs1
Name: enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 93747
HGNC: HGNC:3151
Homologene: 3018
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 21,003,956 bp
  • C to A, chromosome 1 at 44,061,740 bp
  • C to T, chromosome 1 at 54,723,009 bp
  • A to T, chromosome 1 at 59,109,106 bp
  • T to A, chromosome 1 at 139,733,255 bp
  • C to T, chromosome 2 at 30,392,441 bp
  • A to G, chromosome 2 at 62,542,237 bp
  • A to G, chromosome 2 at 92,953,401 bp
  • T to C, chromosome 2 at 133,561,296 bp
  • C to T, chromosome 3 at 90,387,397 bp
  • G to T, chromosome 4 at 5,799,460 bp
  • T to G, chromosome 4 at 101,614,238 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • T to C, chromosome 4 at 127,945,276 bp
  • A to G, chromosome 5 at 34,659,939 bp
  • A to G, chromosome 5 at 86,891,272 bp
  • G to A, chromosome 5 at 112,355,112 bp
  • T to C, chromosome 5 at 139,379,147 bp
  • C to T, chromosome 6 at 142,367,283 bp
  • A to T, chromosome 7 at 12,153,283 bp
  • A to T, chromosome 7 at 17,051,179 bp
  • C to T, chromosome 7 at 19,202,555 bp
  • G to A, chromosome 7 at 23,421,512 bp
  • A to T, chromosome 7 at 102,713,876 bp
  • G to A, chromosome 7 at 131,243,052 bp
  • A to G, chromosome 7 at 140,112,555 bp
  • T to C, chromosome 8 at 4,210,622 bp
  • T to C, chromosome 8 at 4,214,304 bp
  • T to C, chromosome 9 at 36,432,899 bp
  • C to T, chromosome 9 at 45,771,600 bp
  • A to T, chromosome 9 at 50,995,647 bp
  • C to A, chromosome 10 at 4,356,673 bp
  • C to T, chromosome 10 at 34,407,619 bp
  • T to A, chromosome 10 at 58,513,162 bp
  • T to A, chromosome 10 at 79,035,329 bp
  • C to T, chromosome 10 at 80,008,237 bp
  • T to A, chromosome 11 at 5,628,616 bp
  • A to T, chromosome 11 at 5,876,757 bp
  • A to T, chromosome 11 at 40,706,082 bp
  • G to A, chromosome 11 at 51,560,008 bp
  • A to G, chromosome 11 at 73,238,385 bp
  • A to T, chromosome 11 at 98,554,708 bp
  • A to T, chromosome 12 at 101,942,194 bp
  • T to A, chromosome 12 at 104,389,669 bp
  • A to T, chromosome 13 at 118,715,595 bp
  • A to G, chromosome 14 at 8,246,400 bp
  • T to C, chromosome 14 at 26,604,749 bp
  • C to T, chromosome 14 at 33,146,989 bp
  • T to A, chromosome 14 at 56,629,096 bp
  • T to A, chromosome 14 at 78,510,037 bp
  • A to G, chromosome 15 at 5,189,817 bp
  • T to C, chromosome 17 at 12,842,570 bp
  • C to A, chromosome 17 at 20,419,396 bp
  • G to A, chromosome 17 at 24,366,082 bp
  • C to T, chromosome 17 at 43,311,275 bp
  • A to T, chromosome 17 at 45,586,109 bp
  • A to G, chromosome 17 at 79,895,944 bp
  • C to T, chromosome 19 at 11,828,300 bp
  • G to T, chromosome 19 at 21,555,800 bp
  • T to C, chromosome 19 at 42,727,649 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2032 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040039-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.