Strain Name:
C57BL/6J-MtgxR2036Btlr/Mmmh
Stock Number:
040043-MU
Citation ID:
RRID:MMRRC_040043-MU
Other Names:
R2036 (G1), C57BL/6J-MtgxR2036Btlr
Major Collection:

Strain Information

Tln2
Name: talin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70549
VEGA: 9
Homologene: 56692
Cd40
Name: CD40 antigen
Synonyms: Tnfrsf5, Bp50, Cd40, p50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21939
Homologene: 954
Plekha1
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Synonyms: TAPP1, C920009D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101476
Homologene: 11001
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72313
Homologene: 103956
Kif20a
Name: kinesin family member 20A
Synonyms: Rabkinesin-6, Rab6kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19348
VEGA: 18
HGNC: HGNC:9787
Homologene: 38093
Dhdds
Name: dehydrodolichyl diphosphate synthase
Synonyms: 3222401G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67422
Homologene: 32615
Arhgap35
Name: Rho GTPase activating protein 35
Synonyms: 6430596G11Rik, p190A, P190 RhoGAP, p190RhoGAP, Grlf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232906
HGNC: HGNC:4591
Homologene: 35136
Xpo1
Name: exportin 1
Synonyms: Crm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103573
Homologene: 2554
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227446
Homologene: 10834
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100683
Homologene: 39246
Ddb1
Name: damage specific DNA binding protein 1
Synonyms: p127-Ddb1, damage-specific DNA-binding protein, DNA repair, DNA repair protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13194
VEGA: 19
HGNC: HGNC:2717
Homologene: 1448
Capza2
Name: capping actin protein of muscle Z-line subunit alpha 2
Synonyms: 1110053K06Rik, Cappa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12343
HGNC: HGNC:1490
Homologene: 55956
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Cyb5r4
Name: cytochrome b5 reductase 4
Synonyms: b5/b5r, B5+B5R, Ncb5or, 2810034J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 266690
Homologene: 69207
Atg4c
Name: autophagy related 4C, cysteine peptidase
Synonyms: Autl1, Apg4-C, Apg4c, autophagin 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242557
Homologene: 56296
Arhgap17
Name: Rho GTPase activating protein 17
Synonyms: Rich1, 5730403H17Rik, Nadrin, Nadrin2, WBP15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70497
Homologene: 9984
Cdc25c
Name: cell division cycle 25C
Synonyms: Cdc25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12532
VEGA: 18
HGNC: HGNC:1727
Homologene: 1356
Kif22
Name: kinesin family member 22
Synonyms: Kif22a, Kid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 110033
HGNC: HGNC:6391
Homologene: 32011
Arhgap44
Name: Rho GTPase activating protein 44
Synonyms: AU040829
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216831
Homologene: 65284
Dennd6a
Name: DENN domain containing 6A
Synonyms: Fam116a, A630054L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211922
Homologene: 13503
Mphosph9
Name: M-phase phosphoprotein 9
Synonyms: 4930548D04Rik, MPP9, MPP-9, 9630025B04Rik, B930097C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269702
HGNC: HGNC:7215
Homologene: 11256
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: mdfw, ahl, USH1D, nmf252, sals, nmf112, bob, nmf181, 4930542A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Wdr72
Name: WD repeat domain 72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 546144
Homologene: 52326
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: Dnahc2, D330014H01Rik, 2900022L05Rik, Dnhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Arsi
Name: arylsulfatase i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 545260
Homologene: 44428
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 229003
Homologene: 14118
Mboat7
Name: membrane bound O-acyltransferase domain containing 7
Synonyms: Leng4, Lpiat1, 5730589L02Rik, mBB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77582
Homologene: 11510
Pip4p1
Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Synonyms: Tmem55b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219024
Homologene: 10279
Brinp3
Name: bone morphogenetic protein/retinoic acid inducible neural specific 3
Synonyms: Fam5c, B830045N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215378
Homologene: 17786
Ppp2r2c
Name: protein phosphatase 2, regulatory subunit B, gamma
Synonyms: 6330548O06Rik, IMYPNO1, PR52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269643
HGNC: HGNC:9306
Homologene: 36386
Ankar
Name: ankyrin and armadillo repeat containing
Synonyms: 4932422E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 319695
Homologene: 85163
Rtn2
Name: reticulon 2 (Z-band associated protein)
Synonyms: Nspl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20167
Homologene: 32180
AU018091
Name: expressed sequence AU018091
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 245128
Homologene: 106376
Mkrn2
Name: makorin, ring finger protein, 2
Synonyms: 2610002L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67027
HGNC: HGNC:7113
Homologene: 8392
Gm11627
Name: predicted gene 11627
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100040792
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Dnai1
Name: dynein axonemal intermediate chain 1
Synonyms: b2b1526Clo, 1110066F04Rik, Dnaic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68922
HGNC: HGNC:2954
Homologene: 8122
Or5p69
Name: olfactory receptor family 5 subfamily P member 69
Synonyms: GA_x6K02T2PBJ9-10697517-10698461, Olfr494, MOR204-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258732
Homologene: 133602
Or5ae2
Name: olfactory receptor family 5 subfamily AE member 2
Synonyms: MOR254-2, GA_x6K02T2NHDJ-11231385-11230438, Olfr291
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258410
Homologene: 83130
Clnk
Name: cytokine-dependent hematopoietic cell linker
Synonyms: MIST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 27278
Homologene: 8450
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628422
Ctcfl
Name: CCCTC-binding factor like
Synonyms: Boris, OTTMUSG00000016680
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 664799
Homologene: 46476
Akr1c21
Name: aldo-keto reductase family 1, member C21
Synonyms: 9430025F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 77337
Homologene: 134114
Fut9
Name: fucosyltransferase 9
Synonyms: mFuc-TIX, mFUT9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14348
HGNC: HGNC:4020
Homologene: 4800
Sh3tc1
Name: SH3 domain and tetratricopeptide repeats 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231147
Homologene: 10360
Nkd1
Name: naked cuticle 1
Synonyms: 9030215G15Rik, 2810434J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 93960
Homologene: 12343
Or4k41
Name: olfactory receptor family 4 subfamily K member 41
Synonyms: GA_x6K02T2Q125-72500603-72501520, MOR248-15, Olfr1287
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257935
Gba2
Name: glucosidase beta 2
Synonyms: bile acid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230101
Homologene: 10859
Rmnd1
Name: required for meiotic nuclear division 1 homolog
Synonyms: 0610042C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66084
Homologene: 5675
Majin
Name: membrane anchored junction protein
Synonyms: 1700123I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 622554
Homologene: 78163
Tmprss11d
Name: transmembrane protease, serine 11d
Synonyms: AsP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231382
Homologene: 74519
Anks1b
Name: ankyrin repeat and sterile alpha motif domain containing 1B
Synonyms: E530015N03Rik, C030032C09Rik, Gm10937, LOC380650, AIDA-1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77531
Homologene: 51570
Bcl11a
Name: BCL11 transcription factor A
Synonyms: Evi9, Evi9c, CTIP1, D930021L15Rik, mouse myeloid leukemia gene, COUP-TF interacting protein 1, Evi9a, 2810047E18Rik, Evi9b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14025
Homologene: 11284
Ap5b1
Name: adaptor-related protein complex 5, beta 1 subunit
Synonyms: Gm962
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 381201
VEGA: 19
Homologene: 16299
Ddx51
Name: DEAD box helicase 51
Synonyms: 2310061O04Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69663
Homologene: 6850
Kcnmb3
Name: potassium large conductance calcium-activated channel, subfamily M, beta member 3
Synonyms: Gm5707
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100502876
HGNC: HGNC:6287
Homologene: 18141
Or9s15
Name: olfactory receptor family 9 subfamily S member 15
Synonyms: GA_x6K02T2R7CC-81157497-81156526, MOR208-3, Olfr1411
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258483
Homologene: 115530
Or4c110
Name: olfactory receptor family 4 subfamily C member 110
Synonyms: Olfr1215, MOR233-13, GA_x6K02T2Q125-50482823-50481885
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258451
Homologene: 74071
Or6c35
Name: olfactory receptor family 6 subfamily C member 35
Synonyms: Olfr781, MOR114-6, GA_x6K02T2PULF-11013616-11014551
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258723
Homologene: 37000
Gm14177
Name: predicted gene 14177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Or5b95
Name: olfactory receptor family 5 subfamily B member 95
Synonyms: Olfr1443, GA_x6K02T2RE5P-3006492-3007430, MOR202-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258693
HGNC: HGNC:8324
Homologene: 115496
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 72,666,530 bp
  • A to T, chromosome 1 at 92,596,606 bp
  • A to G, chromosome 1 at 105,743,254 bp
  • A to T, chromosome 1 at 146,701,841 bp
  • C to T, chromosome 2 at 89,001,632 bp
  • T to A, chromosome 2 at 111,449,626 bp
  • T to C, chromosome 2 at 165,062,301 bp
  • C to T, chromosome 2 at 173,101,985 bp
  • T to A, chromosome 2 at 181,237,479 bp
  • A to G, chromosome 3 at 32,472,382 bp
  • A to G, chromosome 4 at 25,620,322 bp
  • A to G, chromosome 4 at 41,632,225 bp
  • G to A, chromosome 4 at 43,568,118 bp
  • C to T, chromosome 4 at 99,218,139 bp
  • T to C, chromosome 4 at 133,971,099 bp
  • A to G, chromosome 5 at 35,716,164 bp
  • C to T, chromosome 5 at 36,952,404 bp
  • A to T, chromosome 5 at 38,752,800 bp
  • T to C, chromosome 5 at 73,022,544 bp
  • C to A, chromosome 5 at 73,107,962 bp
  • T to A, chromosome 5 at 86,309,269 bp
  • C to A, chromosome 5 at 110,656,625 bp
  • G to A, chromosome 5 at 124,304,211 bp
  • C to A, chromosome 5 at 144,828,562 bp
  • T to C, chromosome 6 at 17,660,778 bp
  • C to A, chromosome 6 at 115,611,914 bp
  • A to C, chromosome 7 at 3,156,123 bp
  • A to G, chromosome 7 at 3,685,672 bp
  • T to C, chromosome 7 at 16,563,133 bp
  • A to G, chromosome 7 at 19,293,739 bp
  • A to G, chromosome 7 at 41,863,993 bp
  • G to T, chromosome 7 at 84,856,358 bp
  • T to A, chromosome 7 at 108,367,740 bp
  • T to C, chromosome 7 at 123,318,494 bp
  • A to T, chromosome 7 at 127,030,954 bp
  • A to G, chromosome 7 at 130,902,192 bp
  • A to G, chromosome 8 at 88,591,677 bp
  • T to C, chromosome 9 at 67,272,704 bp
  • T to A, chromosome 9 at 74,151,594 bp
  • T to G, chromosome 9 at 87,042,879 bp
  • T to C, chromosome 10 at 4,407,884 bp
  • A to G, chromosome 10 at 60,466,043 bp
  • T to C, chromosome 10 at 90,969,853 bp
  • G to A, chromosome 10 at 129,333,672 bp
  • A to T, chromosome 11 at 23,276,497 bp
  • A to T, chromosome 11 at 24,164,087 bp
  • T to C, chromosome 11 at 65,041,492 bp
  • G to A, chromosome 11 at 69,497,804 bp
  • G to T, chromosome 11 at 76,452,350 bp
  • C to T, chromosome 11 at 99,685,532 bp
  • C to T, chromosome 11 at 102,576,754 bp
  • T to C, chromosome 13 at 4,576,306 bp
  • A to T, chromosome 14 at 26,608,119 bp
  • A to G, chromosome 14 at 50,928,041 bp
  • A to G, chromosome 16 at 17,303,112 bp
  • T to C, chromosome 18 at 34,628,462 bp
  • G to C, chromosome 18 at 34,738,239 bp
  • G to A, chromosome 18 at 60,916,651 bp
  • T to C, chromosome 19 at 5,568,869 bp
  • C to T, chromosome 19 at 6,213,312 bp
  • T to A, chromosome 19 at 10,610,822 bp
  • G to C, chromosome 19 at 12,680,801 bp
  • T to C, chromosome 19 at 57,731,539 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2036 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040043-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.