Strain Name:
C57BL/6J-MtgxR2045Btlr/Mmmh
Stock Number:
040052-MU
Citation ID:
RRID:MMRRC_040052-MU
Other Names:
R2045 (G1), C57BL/6J-MtgxR2045Btlr
Major Collection:

Gene Information

Cdh1
Name: cadherin 1
Synonyms: Ecad, uvomorulin, E-cad, UM, L-CAM, E-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Igfbp2
Name: insulin-like growth factor binding protein 2
Synonyms: Igfbp-2, IGFBP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16008
HGNC: HGNC:5471
Homologene: 499
Vcan
Name: versican
Synonyms: Cspg2, hdf, 5430420N07Rik, heart defect, DPEAAE, PG-M
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: ne, 6030440P17Rik, 8430406N05Rik, my, b2b1562Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242022
Homologene: 18454
Atf2
Name: activating transcription factor 2
Synonyms: mXBP, CRE-BP, D130078H02Rik, Creb2, ATF-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11909
HGNC: HGNC:784
Homologene: 31061
Pcf11
Name: PCF11 cleavage and polyadenylation factor subunit
Synonyms: 2500001H09Rik, 5730417B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74737
Homologene: 32282
Lypd1
Name: Ly6/Plaur domain containing 1
Synonyms: C530008O16Rik, Lynx2, 2700050C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72585
Homologene: 16937
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Fr1, Eask, Flt-2, Hspy, Fgfr-1, FGFR-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: p53BP1, 53BP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27223
Homologene: 4137
Asah2
Name: N-acylsphingosine amidohydrolase 2
Synonyms: neutral/alkaline ceramidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 54447
VEGA: 19
Homologene: 10310
Tut7
Name: terminal uridylyl transferase 7
Synonyms: 6030448M23Rik, Zcchc6, Tent3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Sbno1
Name: strawberry notch 1
Synonyms: 9330180L10Rik, sno
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243272
Homologene: 10055
Bms1
Name: BMS1, ribosome biogenesis factor
Synonyms: Bms1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213895
Homologene: 7065
Eef1b2
Name: eukaryotic translation elongation factor 1 beta 2
Synonyms: 2810017J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 55949
HGNC: HGNC:3208
Homologene: 1480
Senp1
Name: SUMO1/sentrin specific peptidase 1
Synonyms: D15Ertd528e, E330036L07Rik, 2310046A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223870
Homologene: 8731
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329908
Homologene: 35420
Rnpc3
Name: RNA-binding region (RNP1, RRM) containing 3
Synonyms: 2810441O16Rik, C030014B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67225
Homologene: 9746
Cyfip2
Name: cytoplasmic FMR1 interacting protein 2
Synonyms: Pir121, 1500004I01Rik, 6430511D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76884
Homologene: 7936
Trappc10
Name: trafficking protein particle complex 10
Synonyms: Tmem1, b2b2613Clo, b2b2416Clo, LOC380642, B230307C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216131
VEGA: 10
Homologene: 37751
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: PipkIII, Pip5k3, 5230400C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18711
Homologene: 32115
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71722
Homologene: 87637
Erap1
Name: endoplasmic reticulum aminopeptidase 1
Synonyms: Arts1, ERAAP, PILSAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 80898
VEGA: 13
Homologene: 56754
Nmb
Name: neuromedin B
Synonyms: 3110023K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68039
HGNC: HGNC:7842
Homologene: 36392
Itgb3
Name: integrin beta 3
Synonyms: CD61, platelet glycoprotein IIIa (GP3A)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16416
HGNC: HGNC:6156
Homologene: 55444
Sft2d2
Name: SFT2 domain containing 2
Synonyms: 2010005O13Rik, cI-45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108735
Homologene: 27069
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Far1
Name: fatty acyl CoA reductase 1
Synonyms: 2900034E22Rik, 3732409C05Rik, 2600011M19Rik, Mlstd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67420
Homologene: 41718
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: b2b414Clo, 4432416O06Rik, m407Asp, DHC2, DHC1b, D330044F14Rik, Dnchc2, D030010H02Rik, m152Asp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Smad4
Name: SMAD family member 4
Synonyms: Smad 4, Madh4, D18Wsu70e, DPC4, Dpc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17128
HGNC: HGNC:6770
Homologene: 31310
Atp5pb
Name: ATP synthase peripheral stalk-membrane subunit b
Synonyms: C76477, Atp5f1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11950
HGNC: HGNC:840
Homologene: 1275
Cngb1
Name: cyclic nucleotide gated channel beta 1
Synonyms: Cngb1b, Cngb1, BC016201
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 333329
HGNC: HGNC:2151
Homologene: 136420
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: CED-5, MBC, Hch
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Zfp287
Name: zinc finger protein 287
Synonyms: SKAT-2, B230333C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 170740
Homologene: 23244
Tamm41
Name: TAM41 mitochondrial translocator assembly and maintenance homolog
Synonyms: 1500001M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68971
Homologene: 13754
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: (alpha)1 subunit, Cchl1a1, Cav1.2, L-type Cav1.2, D930026N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
Acta2
Name: actin alpha 2, smooth muscle, aorta
Synonyms: a-SMA, alphaSMA, SMalphaA, 0610041G09Rik, Actvs, SMAalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11475
VEGA: 19
HGNC: HGNC:130
Homologene: 133938
Med12l
Name: mediator complex subunit 12-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329650
Homologene: 43143
Unc13b
Name: unc-13 homolog B
Synonyms: Unc13h2, Munc13-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22249
Homologene: 31376
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208169
Homologene: 19505
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Dnahc7l, DLP12, HL19, DHC3, 4921531P07Rik, LOC380889, Dnahc12, Hdhc3, HL-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, fibrocystin L, PKHDL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: b2b585Clo, PC6, PC5A, SPC6, b2b1549Clo, PC5/6A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Nudt8
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 8
Synonyms: 2310039H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66387
VEGA: 19
HGNC: HGNC:8055
Homologene: 41633
Fbn2
Name: fibrillin 2
Synonyms: Sne, Fib-2, sy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Lrguk
Name: leucine-rich repeats and guanylate kinase domain containing
Synonyms: 4921528H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74354
Homologene: 34923
Fam214a
Name: family with sequence similarity 214, member A
Synonyms: 6330415I01Rik, BC031353, C130047D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235493
VEGA: 9
Homologene: 35065
Capn8
Name: calpain 8
Synonyms: nCL-2, nCL-2'
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 170725
HGNC: HGNC:1485
Homologene: 15643
Phlpp2
Name: PH domain and leucine rich repeat protein phosphatase 2
Synonyms: C130044A18Rik, Phlppl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244650
Homologene: 71015
Adamts1
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
Synonyms: ADAMTS-1, METH1, ADAM-TS1, METH-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11504
HGNC: HGNC:217
Homologene: 21381
Padi2
Name: peptidyl arginine deiminase, type II
Synonyms: PAD type II, Pdi2, Pdi
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18600
Homologene: 7214
Pop5
Name: processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
Synonyms: 2700077E03Rik, 1500019J17Rik, Rnasep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117109
Homologene: 41076
Mylk
Name: myosin, light polypeptide kinase
Synonyms: Mlck, 9530072E15Rik, A930019C19Rik, MLCK108, MLCK210, nmMlck, telokin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Rab32
Name: RAB32, member RAS oncogene family
Synonyms: 2810011A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67844
HGNC: HGNC:9772
Homologene: 38233
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Hip1r
Name: huntingtin interacting protein 1 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 29816
Homologene: 78348
Fpr-rs4
Name: formyl peptide receptor, related sequence 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14291
Homologene: 130629
Cd226
Name: CD226 antigen
Synonyms: DNAM-1, TLiSA1, DNAM1, Pta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225825
Homologene: 4787
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16565
Homologene: 56868
Cadps2
Name: Ca2+-dependent activator protein for secretion 2
Synonyms: A230044C21Rik, Caps2, cpd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320405
Homologene: 23060
Lcp1
Name: lymphocyte cytosolic protein 1
Synonyms: D14Ertd310e, L-plastin, L-fimbrin, Pls2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18826
HGNC: HGNC:6528
Homologene: 80174
Krt7
Name: keratin 7
Synonyms: K7, Krt2-7, D15Wsu77e, Cytokeratin 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110310
HGNC: HGNC:6445
Homologene: 4058
Nek4
Name: NIMA (never in mitosis gene a)-related expressed kinase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 23955
VEGA: 14
Homologene: 2376
Vax2
Name: ventral anterior homeobox 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 24113
Homologene: 8048
Mrgpra9
Name: MAS-related GPR, member A9
Synonyms: EG668725, MrgA9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 668725
Homologene: 79615
Bag4
Name: BCL2-associated athanogene 4
Synonyms: 2410112I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67384
HGNC: HGNC:940
Homologene: 31270
Prkag2
Name: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Synonyms: 2410051C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108099
HGNC: HGNC:9386
Homologene: 136125
Ptpn22
Name: protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Synonyms: 70zpep, Ptpn8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19260
HGNC: HGNC:9652
Homologene: 7498
Zbtb7a
Name: zinc finger and BTB domain containing 7a
Synonyms: FBI-1, 9130006G12Rik, Leukemia/lymphoma Related Factor, Lrf, 9030619K07Rik, Pokemon, Zbtb7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16969
Homologene: 7820
Insyn2a
Name: inhibitory synaptic factor 2A
Synonyms: B830028B13Rik, Fam196a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 627214
Homologene: 85469
Cd33
Name: CD33 antigen
Synonyms: gp67, Siglec-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12489
HGNC: HGNC:1659
Chit1
Name: chitinase 1 (chitotriosidase)
Synonyms: 2300002L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71884
HGNC: HGNC:1936
Homologene: 68318
Ankrd63
Name: ankyrin repeat domain 63
Synonyms: Gm1337, LOC383787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 383787
Homologene: 19774
Krtdap
Name: keratinocyte differentiation associated protein
Synonyms: Kdap, sk221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 64661
Homologene: 52619
Tbx6
Name: T-box 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21389
Homologene: 3389
Ccdc9b
Name: coiled-coil domain containing 9B
Synonyms: A430105I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214239
Homologene: 128188
Ankef1
Name: ankyrin repeat and EF-hand domain containing 1
Synonyms: Ankrd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319196
Homologene: 11130
Oosp3
Name: oocyte secreted protein 3
Synonyms: Gm97, LOC225923
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225923
Lipi
Name: lipase, member I
Synonyms: D930038D03Rik, lpd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 320355
Homologene: 77864
Gm8005
Name: predicted gene 8005
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 666253
Homologene: 128452
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 63,179,487 bp
  • T to C, chromosome 1 at 65,253,353 bp
  • A to G, chromosome 1 at 72,852,151 bp
  • G to A, chromosome 1 at 125,910,535 bp
  • A to G, chromosome 1 at 134,151,144 bp
  • G to A, chromosome 1 at 136,160,313 bp
  • A to G, chromosome 1 at 165,185,078 bp
  • A to G, chromosome 1 at 182,613,386 bp
  • A to C, chromosome 2 at 73,863,208 bp
  • C to A, chromosome 2 at 118,703,353 bp
  • C to A, chromosome 2 at 118,761,631 bp
  • C to A, chromosome 2 at 121,204,483 bp
  • T to C, chromosome 2 at 136,554,738 bp
  • A to T, chromosome 3 at 53,535,744 bp
  • A to T, chromosome 3 at 59,262,310 bp
  • C to T, chromosome 3 at 96,651,738 bp
  • T to A, chromosome 3 at 103,874,021 bp
  • T to C, chromosome 3 at 105,943,874 bp
  • T to C, chromosome 3 at 113,608,360 bp
  • A to G, chromosome 3 at 144,925,163 bp
  • G to A, chromosome 4 at 43,091,266 bp
  • T to C, chromosome 4 at 106,400,980 bp
  • A to T, chromosome 4 at 140,937,930 bp
  • A to G, chromosome 5 at 24,947,582 bp
  • T to G, chromosome 5 at 115,238,212 bp
  • T to C, chromosome 5 at 124,000,731 bp
  • T to C, chromosome 5 at 124,413,302 bp
  • A to G, chromosome 6 at 23,839,122 bp
  • A to T, chromosome 6 at 34,071,068 bp
  • G to A, chromosome 6 at 83,711,270 bp
  • T to A, chromosome 6 at 115,016,095 bp
  • A to C, chromosome 6 at 118,392,627 bp
  • A to G, chromosome 6 at 118,656,137 bp
  • C to A, chromosome 7 at 25,271,536 bp
  • T to A, chromosome 7 at 30,790,585 bp
  • G to T, chromosome 7 at 43,529,892 bp
  • A to T, chromosome 7 at 47,235,835 bp
  • T to C, chromosome 7 at 80,904,811 bp
  • G to T, chromosome 7 at 92,661,879 bp
  • A to T, chromosome 7 at 113,539,271 bp
  • T to A, chromosome 7 at 126,782,883 bp
  • T to G, chromosome 7 at 134,918,430 bp
  • A to G, chromosome 8 at 25,558,215 bp
  • C to T, chromosome 8 at 25,769,488 bp
  • T to A, chromosome 8 at 95,297,085 bp
  • T to C, chromosome 8 at 106,666,182 bp
  • T to A, chromosome 8 at 109,907,600 bp
  • A to T, chromosome 9 at 7,160,171 bp
  • A to G, chromosome 9 at 75,012,927 bp
  • T to G, chromosome 10 at 10,550,833 bp
  • T to C, chromosome 10 at 78,209,479 bp
  • C to A, chromosome 10 at 81,144,410 bp
  • T to C, chromosome 10 at 93,038,809 bp
  • T to C, chromosome 11 at 34,294,106 bp
  • T to C, chromosome 11 at 46,249,789 bp
  • A to G, chromosome 11 at 62,727,569 bp
  • T to G, chromosome 11 at 104,623,413 bp
  • T to C, chromosome 13 at 59,800,656 bp
  • T to C, chromosome 13 at 74,669,450 bp
  • T to A, chromosome 13 at 89,690,985 bp
  • A to G, chromosome 14 at 26,781,528 bp
  • T to A, chromosome 14 at 30,953,923 bp
  • A to G, chromosome 14 at 42,434,929 bp
  • A to T, chromosome 14 at 75,200,401 bp
  • A to T, chromosome 15 at 44,479,654 bp
  • A to T, chromosome 15 at 98,059,944 bp
  • A to T, chromosome 15 at 101,423,484 bp
  • A to G, chromosome 16 at 34,953,653 bp
  • G to A, chromosome 16 at 45,580,250 bp
  • G to A, chromosome 16 at 75,550,199 bp
  • A to T, chromosome 16 at 85,795,976 bp
  • CAGGAA to CA, chromosome 17 at 18,022,334 bp
  • A to T, chromosome 18 at 58,090,658 bp
  • A to T, chromosome 18 at 73,649,806 bp
  • T to C, chromosome 18 at 89,207,362 bp
  • T to C, chromosome 19 at 4,001,899 bp
  • T to A, chromosome 19 at 11,699,369 bp
  • T to C, chromosome 19 at 17,581,144 bp
  • A to T, chromosome 19 at 32,052,956 bp
  • C to T, chromosome 19 at 34,243,399 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2045 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040052-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.