Strain Name:
C57BL/6J-MtgxR2046Btlr/Mmmh
Stock Number:
040053-MU
Citation ID:
RRID:MMRRC_040053-MU
Other Names:
R2046 (G1), C57BL/6J-MtgxR2046Btlr
Major Collection:

Gene Information

Pofut2
Name: protein O-fucosyltransferase 2
Synonyms: FUT13, 2310011G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 80294
VEGA: 10
Homologene: 12724
Epha4
Name: Eph receptor A4
Synonyms: Tyro1, rb, 2900005C20Rik, Sek, Sek1, Hek8, Cek8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13838
HGNC: HGNC:3388
Homologene: 20933
Slc6a2
Name: solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
Synonyms: NE transporter, Slc6a5, norepinephrine transporter, NET
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20538
Homologene: 816
Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Synonyms: ErbB4, Her4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13869
HGNC: HGNC:3432
Homologene: 21084
Fzd9
Name: frizzled class receptor 9
Synonyms: frizzled 9, mfz9, Fz9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14371
HGNC: HGNC:4047
Homologene: 2619
Taf8
Name: TATA-box binding protein associated factor 8
Synonyms: Tbn, Taf8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 63856
VEGA: 17
Homologene: 11094
Dgka
Name: diacylglycerol kinase, alpha
Synonyms: Dagk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13139
VEGA: 10
HGNC: HGNC:2849
Homologene: 1028
Plcd3
Name: phospholipase C, delta 3
Synonyms: 2610205J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72469
HGNC: HGNC:9061
Homologene: 14858
Dock5
Name: dedicator of cytokinesis 5
Synonyms: rlc, 1110060D06Rik, lr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 68813
VEGA: 14
Homologene: 57016
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Usp28
Name: ubiquitin specific peptidase 28
Synonyms: 9830148O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235323
VEGA: 9
Homologene: 10840
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216860
Homologene: 13029
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103554
Homologene: 113742
Smc3
Name: structural maintenance of chromosomes 3
Synonyms: Cspg6, Bamacan, Mmip1, SmcD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13006
HGNC: HGNC:2468
Homologene: 3974
Ccnb2
Name: cyclin B2
Synonyms: CycB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12442
VEGA: 9
HGNC: HGNC:1580
Homologene: 74359
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27103
Homologene: 40891
Arid2
Name: AT rich interactive domain 2 (ARID, RFX-like)
Synonyms: zipzap/p200, 4432409D24Rik, 1700124K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 77044
Homologene: 14601
Bend3
Name: BEN domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 331623
VEGA: 10
Homologene: 19511
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Casp3
Name: caspase 3
Synonyms: A830040C14Rik, AC-3, CC3, CPP32, Caspase-3, Yama, Apopain, mldy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12367
HGNC: HGNC:1504
Homologene: 37912
Fam83h
Name: family with sequence similarity 83, member H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105732
VEGA: 15
Homologene: 15890
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, 2310003F20Rik, Garnl1, Tulip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56784
VEGA: 12
Homologene: 84805
Abcc5
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 5
Synonyms: Abcc5b, Abcc5a, Mrp5, 2900011L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Pygo2
Name: pygopus 2
Synonyms: 1190004M21Rik, mpygo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68911
Homologene: 44519
Bdkrb1
Name: bradykinin receptor, beta 1
Synonyms: kinin B1, B1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 12061
HGNC: HGNC:1029
Homologene: 570
Trim2
Name: tripartite motif-containing 2
Synonyms: narf, neural activity-related ring finger protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80890
Homologene: 22882
Eps15
Name: epidermal growth factor receptor pathway substrate 15
Synonyms: 2410112D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13858
HGNC: HGNC:3419
Homologene: 128359
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, 4921518A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 71175
VEGA: 15
Homologene: 15850
Nelfb
Name: negative elongation factor complex member B
Synonyms: Cobra1, A730008L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58202
Homologene: 121600
Rbm45
Name: RNA binding motif protein 45
Synonyms: Drbp1, G430095G15Rik, Drb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241490
Homologene: 15560
March6
Name: membrane-associated ring finger (C3HC4) 6
Synonyms: F830029L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223455
VEGA: 15
Homologene: 4301
Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Synonyms: Nor1, MINOR, NOR-1, TEC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18124
HGNC: HGNC:7982
Homologene: 5074
Vps37d
Name: vacuolar protein sorting 37D
Synonyms: Wbscr24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 194309
Homologene: 45580
Itga11
Name: integrin alpha 11
Synonyms: 4732459H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319480
HGNC: HGNC:6136
Homologene: 8151
Reln
Name: reelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Pitx3
Name: paired-like homeodomain transcription factor 3
Synonyms: Ptx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18742
HGNC: HGNC:9006
Homologene: 3689
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Ppp1r3a
Name: protein phosphatase 1, regulatory subunit 3A
Synonyms: GM, RGL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 140491
HGNC: HGNC:9291
Homologene: 48124
Ush2a
Name: usherin
Synonyms: Ush2a, Ushrn, MUSH2A, A930037M10Rik, A930011D15Rik, LOC269160, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
Homologene: 66151
Zfp637
Name: zinc finger protein 637
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232337
Homologene: 5069
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78309
Homologene: 56696
Kcnn3
Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
Synonyms: small conductance calcium-activated potassium channel 3, SK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 140493
HGNC: HGNC:6292
Homologene: 20516
Cdkl3
Name: cyclin-dependent kinase-like 3
Synonyms: B230379H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 213084
Homologene: 49467
4930402H24Rik
Name: RIKEN cDNA 4930402H24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228602
Homologene: 12623
Nek9
Name: NIMA (never in mitosis gene a)-related expressed kinase 9
Synonyms: C130021H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217718
Homologene: 13222
Ucp1
Name: uncoupling protein 1 (mitochondrial, proton carrier)
Synonyms: Slc25a7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 22227
Homologene: 22524
Dpy19l1
Name: dpy-19-like 1 (C. elegans)
Synonyms: 1100001I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244745
Homologene: 14762
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: EGF-TM7, FIRE, Gpr127, Emr4, D17Ertd479e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 52614
VEGA: 17
Homologene: 64640
Slco2b1
Name: solute carrier organic anion transporter family, member 2b1
Synonyms: Slc21a9, OATP-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101488
Homologene: 21419
Myo5b
Name: myosin VB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Rsph4a
Name: radial spoke head 4 homolog A (Chlamydomonas)
Synonyms: Rshl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 212892
Homologene: 71779
Gm10647
Name: predicted gene 10647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Gp6
Name: glycoprotein 6 (platelet)
Synonyms: Gpvi, 9830166G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243816
Homologene: 9488
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20684
Homologene: 86761
4930503L19Rik
Name: RIKEN cDNA 4930503L19 gene
Synonyms: Las2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 269033
Homologene: 52120
Zfp110
Name: zinc finger protein 110
Synonyms: NRIF, 2900024E01Rik, Nrif1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 65020
Homologene: 129707
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76645
Homologene: 124481
Klri2
Name: killer cell lectin-like receptor family I member 2
Synonyms: A530090P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320407
Homologene: 86736
Arhgef33
Name: Rho guanine nucleotide exchange factor (GEF) 33
Synonyms: Gm941, LOC381112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381112
VEGA: 17
Homologene: 55190
Olfr1099
Name: olfactory receptor 1099
Synonyms: MOR206-3, GA_x6K02T2Q125-48446067-48445129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258764
Homologene: 107003
Nrm
Name: nurim (nuclear envelope membrane protein)
Synonyms: 2610307M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106582
HGNC: HGNC:8003
Homologene: 38294
Sardh
Name: sarcosine dehydrogenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 192166
Homologene: 5149
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Dzip1
Name: DAZ interacting protein 1
Synonyms: 2810422M04Rik, 2510025K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66573
VEGA: 14
Homologene: 45708
Lztr1
Name: leucine-zipper-like transcriptional regulator, 1
Synonyms: 1200003E21Rik, TCFL2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66863
HGNC: HGNC:6742
Homologene: 4925
Dhrs7
Name: dehydrogenase/reductase (SDR family) member 7
Synonyms: 5730564L20Rik, retDSR4, retSDR4, 2310016E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 66375
VEGA: 12
Homologene: 9350
Slc38a11
Name: solute carrier family 38, member 11
Synonyms: 9330158F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320106
Homologene: 5775
Vwa2
Name: von Willebrand factor A domain containing 2
Synonyms: Amaco
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240675
Homologene: 18238
Card10
Name: caspase recruitment domain family, member 10
Synonyms: CARMA3, Bimp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105844
Homologene: 8728
Gm4951
Name: predicted gene 4951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240327
Pus7l
Name: pseudouridylate synthase 7-like
Synonyms: 3000003F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 78895
Homologene: 12842
Fancg
Name: Fanconi anemia, complementation group G
Synonyms: Xrcc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 60534
HGNC: HGNC:3588
Homologene: 3402
Spns2
Name: spinster homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216892
Homologene: 71040
Sh3tc2
Name: SH3 domain and tetratricopeptide repeats 2
Synonyms: D430044G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225608
VEGA: 18
Homologene: 11596
Clec4n
Name: C-type lectin domain family 4, member n
Synonyms: Clecsf10, dectin-2, Nkcl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56620
Homologene: 84615
Crtac1
Name: cartilage acidic protein 1
Synonyms: Lotus, Crtac1B, 2810454P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72832
VEGA: 19
Homologene: 23070
Rmi1
Name: RecQ mediated genome instability 1
Synonyms: 4932432N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 74386
VEGA: 13
Homologene: 41601
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 68,298,323 bp
  • T to C, chromosome 1 at 77,507,162 bp
  • G to A, chromosome 1 at 85,709,065 bp
  • C to T, chromosome 1 at 153,141,765 bp
  • A to G, chromosome 1 at 188,356,927 bp
  • T to A, chromosome 2 at 25,206,311 bp
  • A to T, chromosome 2 at 27,215,082 bp
  • A to G, chromosome 2 at 65,358,185 bp
  • G to A, chromosome 2 at 76,375,398 bp
  • C to A, chromosome 2 at 76,907,794 bp
  • C to A, chromosome 2 at 86,958,733 bp
  • A to T, chromosome 2 at 118,451,408 bp
  • T to A, chromosome 2 at 130,810,917 bp
  • A to G, chromosome 3 at 84,208,289 bp
  • T to A, chromosome 3 at 89,433,148 bp
  • T to A, chromosome 3 at 89,667,077 bp
  • A to G, chromosome 4 at 43,004,604 bp
  • A to G, chromosome 4 at 48,067,807 bp
  • T to C, chromosome 4 at 109,370,596 bp
  • T to C, chromosome 5 at 21,942,627 bp
  • G to T, chromosome 5 at 124,796,341 bp
  • T to A, chromosome 5 at 135,073,977 bp
  • A to G, chromosome 5 at 135,249,684 bp
  • T to C, chromosome 6 at 14,722,104 bp
  • A to G, chromosome 6 at 117,845,772 bp
  • T to A, chromosome 6 at 123,246,504 bp
  • T to A, chromosome 6 at 129,733,793 bp
  • A to T, chromosome 7 at 4,394,538 bp
  • A to G, chromosome 7 at 12,849,422 bp
  • T to C, chromosome 7 at 97,661,677 bp
  • A to G, chromosome 7 at 99,690,479 bp
  • T to A, chromosome 8 at 46,629,726 bp
  • T to C, chromosome 8 at 83,295,364 bp
  • C to A, chromosome 8 at 92,972,926 bp
  • C to T, chromosome 8 at 116,999,955 bp
  • T to A, chromosome 9 at 24,423,159 bp
  • T to A, chromosome 9 at 49,039,075 bp
  • C to T, chromosome 9 at 62,727,697 bp
  • A to G, chromosome 9 at 66,798,237 bp
  • A to G, chromosome 9 at 70,409,347 bp
  • T to G, chromosome 10 at 33,914,543 bp
  • T to C, chromosome 10 at 43,511,846 bp
  • A to G, chromosome 10 at 77,260,594 bp
  • T to C, chromosome 10 at 128,723,535 bp
  • A to G, chromosome 11 at 30,817,723 bp
  • G to T, chromosome 11 at 52,026,850 bp
  • A to G, chromosome 11 at 69,908,697 bp
  • A to G, chromosome 11 at 72,459,040 bp
  • A to T, chromosome 11 at 83,336,386 bp
  • C to T, chromosome 11 at 103,077,877 bp
  • C to T, chromosome 12 at 55,695,160 bp
  • T to G, chromosome 12 at 72,652,266 bp
  • T to A, chromosome 12 at 85,320,707 bp
  • T to A, chromosome 12 at 105,604,726 bp
  • T to C, chromosome 13 at 58,407,958 bp
  • A to T, chromosome 14 at 67,812,142 bp
  • A to T, chromosome 14 at 118,922,478 bp
  • G to A, chromosome 15 at 8,324,467 bp
  • A to G, chromosome 15 at 31,486,434 bp
  • T to C, chromosome 15 at 76,002,938 bp
  • A to T, chromosome 15 at 78,787,473 bp
  • T to C, chromosome 15 at 94,540,785 bp
  • G to A, chromosome 15 at 96,369,387 bp
  • T to C, chromosome 16 at 17,522,369 bp
  • A to T, chromosome 16 at 20,399,817 bp
  • G to A, chromosome 17 at 35,864,217 bp
  • C to A, chromosome 17 at 46,543,733 bp
  • A to G, chromosome 17 at 47,490,276 bp
  • A to G, chromosome 17 at 55,778,847 bp
  • G to C, chromosome 17 at 80,373,466 bp
  • T to A, chromosome 18 at 60,245,499 bp
  • A to G, chromosome 18 at 61,990,843 bp
  • T to A, chromosome 18 at 70,467,482 bp
  • A to T, chromosome 18 at 74,577,455 bp
  • C to T, chromosome 19 at 42,334,053 bp
  • T to C, chromosome 19 at 46,137,179 bp
  • G to A, chromosome 19 at 53,639,414 bp
  • T to G, chromosome 19 at 56,905,578 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2046 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040053-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.