Strain Name:
C57BL/6J-MtgxR2121Btlr/Mmmh
Stock Number:
040125-MU
Citation ID:
RRID:MMRRC_040125-MU
Other Names:
R2121 (G1), C57BL/6J-MtgxR2121Btlr
Major Collection:

Gene Information

Ppp2r2a
Name: protein phosphatase 2, regulatory subunit B, alpha
Synonyms: 2410004D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71978
VEGA: 14
HGNC: HGNC:9304
Homologene: 2035
Cdh1
Name: cadherin 1
Synonyms: uvomorulin, UM, L-CAM, Ecad, E-cadherin, E-cad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Arpp21
Name: cyclic AMP-regulated phosphoprotein, 21
Synonyms: R3hdm3, ARPP-21, 0710001E13Rik, Tarpp, D9Bwg1012e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74100
Homologene: 32306
Tfdp2
Name: transcription factor Dp 2
Synonyms: DP3, 1110029I05Rik, DP3, A330080J22Rik, DP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 211586
Homologene: 4578
Arhgef10
Name: Rho guanine nucleotide exchange factor (GEF) 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234094
Homologene: 22827
Ctdspl2
Name: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
Synonyms: SCP4, D2Ertd485e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329506
Homologene: 32311
Hcn4
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 330953
VEGA: 9
Homologene: 3997
Snx3
Name: sorting nexin 3
Synonyms: SDP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 54198
Homologene: 36144
Ythdf3
Name: YTH N6-methyladenosine RNA binding protein 3
Synonyms: 9130022A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229096
Homologene: 34991
Diaph1
Name: diaphanous related formin 1
Synonyms: Dia1, mDia1, Drf1, p140mDia, D18Wsu154e, Diap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Fancl
Name: Fanconi anemia, complementation group L
Synonyms: Pog, gcd, 2010322C19Rik, B230118H11Rik, Phf9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67030
Homologene: 9987
Mdc1
Name: mediator of DNA damage checkpoint 1
Synonyms: NFBD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240087
Homologene: 67092
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 217995
VEGA: 13
Homologene: 34562
Palb2
Name: partner and localizer of BRCA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233826
Homologene: 11652
Abcg5
Name: ATP binding cassette subfamily G member 5
Synonyms: cmp, Sterolin-1, trac
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27409
Homologene: 31909
Ncbp3
Name: nuclear cap binding subunit 3
Synonyms: 1200014J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66874
Homologene: 10231
Kctd5
Name: potassium channel tetramerisation domain containing 5
Synonyms: 2610030N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 69259
Homologene: 10363
Smc5
Name: structural maintenance of chromosomes 5
Synonyms: Smc5l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226026
VEGA: 19
Homologene: 41009
Cntn2
Name: contactin 2
Synonyms: D130012K04Rik, Tax, axonin, TAG-1, TAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: Jmjd1b, 5830462I21Rik, JHDM2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Ambn
Name: ameloblastin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11698
HGNC: HGNC:452
Homologene: 7625
Dcdc2a
Name: doublecortin domain containing 2a
Synonyms: RU2, Dcdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 195208
Homologene: 9483
Adnp2
Name: ADNP homeobox 2
Synonyms: Zfp508, 8430420L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240442
Homologene: 8945
Olfm4
Name: olfactomedin 4
Synonyms: GC1, LOC380924, pPD4, OlfD, GW112, LOC239192
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380924
VEGA: 14
Homologene: 4684
Mme
Name: membrane metallo endopeptidase
Synonyms: NEP, 6030454K05Rik, CD10, neutral endopeptidase, neprilysin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 17380
HGNC: HGNC:7154
Homologene: 5275
Cog1
Name: component of oligomeric golgi complex 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16834
HGNC: HGNC:6545
Homologene: 8411
Ikbkb
Name: inhibitor of kappaB kinase beta
Synonyms: IKK-2, IKK-beta, IKKbeta, IKK2, IKK[b]
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16150
HGNC: HGNC:5960
Homologene: 7782
Tmem81
Name: transmembrane protein 81
Synonyms: 4930429O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74626
Homologene: 12579
Soga1
Name: suppressor of glucose, autophagy associated 1
Synonyms: D430036N24Rik, 9830001H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320706
Homologene: 52382
Ctnnd2
Name: catenin (cadherin associated protein), delta 2
Synonyms: neurojugin, Catnd2, Nprap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18163
VEGA: 15
HGNC: HGNC:2516
Homologene: 55574
Tub
Name: tubby bipartite transcription factor
Synonyms: tub, rd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22141
Homologene: 31147
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b3491Clo, b2b1565Clo, Mdnah5, b2b1154Clo, b2b1537Clo, b2b1134Clo, Dnahc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Pde10a
Name: phosphodiesterase 10A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 23984
HGNC: HGNC:8772
Homologene: 4852
Intu
Name: inturned planar cell polarity protein
Synonyms: 9230116I04Rik, Pdzd6, Pdzk6, 9430087H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 380614
Homologene: 41059
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: 9430031G15Rik, Ltbp1L, b2b1000Clo, LTBP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Akna
Name: AT-hook transcription factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100182
Homologene: 49947
Ttc25
Name: tetratricopeptide repeat domain 25
Synonyms: 4933404O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74407
Homologene: 12860
Aox3
Name: aldehyde oxidase 3
Synonyms: AOH1, 1200011D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71724
Homologene: 90899
F13a1
Name: coagulation factor XIII, A1 subunit
Synonyms: Factor XIIIA, 1200014I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 74145
VEGA: 13
HGNC: HGNC:3531
Homologene: 20077
Gstm7
Name: glutathione S-transferase, mu 7
Synonyms: 0610005A07Rik, Cd203c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68312
HGNC: HGNC:4634
Homologene: 41816
Tmed11
Name: transmembrane p24 trafficking protein 11
Synonyms: 1810008K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67366
Homologene: 48721
Vwa5b1
Name: von Willebrand factor A domain containing 5B1
Synonyms: 4931403E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75718
Homologene: 19431
Psg20
Name: pregnancy-specific glycoprotein 20
Synonyms: EG434540, cea7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434540
Homologene: 110989
Serpina3m
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3M
Synonyms: alpha-1 antiproteinase, Spi-2l, Spi2.4, antitrypsin, Spi-2rs1, MMSPi2.4, Spi2-rs1, 3e46, MMCM7, contrapsin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20717
HGNC: HGNC:16
Homologene: 111129
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 622434
Homologene: 9204
Bscl2
Name: Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Synonyms: Gng3lg, seipin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14705
Homologene: 32032
Mybphl
Name: myosin binding protein H-like
Synonyms: 1110037P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68753
Homologene: 19221
Vmn2r121
Name: vomeronasal 2, receptor 121
Synonyms: EG625699
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 100038941
Homologene: 129606
Col20a1
Name: collagen, type XX, alpha 1
Synonyms: 1700051I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 73368
Homologene: 75138
Syt10
Name: synaptotagmin X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 54526
Homologene: 10303
Slc6a21
Name: solute carrier family 6 member 21
Synonyms: 1700039E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76713
Homologene: 66347
Thegl
Name: theg spermatid protein like
Synonyms: 1700023E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71868
Homologene: 128474
Ints6l
Name: integrator complex subunit 6 like
Synonyms: 4930535D10Rik, Ddx26b, 6330505F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 236790
Homologene: 52110
Olfr1045
Name: olfactory receptor 1045
Synonyms: MOR185-2, GA_x6K02T2Q125-47672825-47671878
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 259019
Homologene: 128246
Tnfsf11
Name: tumor necrosis factor (ligand) superfamily, member 11
Synonyms: OPGL, RANKL, Ly109l, Trance, ODF, OPGL, osteoclast differentiation factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21943
VEGA: 14
Homologene: 2744
Prl3c1
Name: prolactin family 3, subfamily c, member 1
Synonyms: PLP-J, PLP I, Prlpj
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 27372
Homologene: 49353
Tll1
Name: tolloid-like
Synonyms: Tll-1, b2b2476Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21892
Homologene: 49202
Nlrp6
Name: NLR family, pyrin domain containing 6
Synonyms: Nalp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101613
Homologene: 15881
Mageb5
Name: melanoma antigen, family B, 5
Synonyms: 1700056A17Rik, mMage-b5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 74271
Homologene: 135943
Cyp2a12
Name: cytochrome P450, family 2, subfamily a, polypeptide 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13085
Homologene: 69128
Mlc1
Name: megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Synonyms: WKL1, Kiaa0027-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 170790
Homologene: 15775
Olfr866
Name: olfactory receptor 866
Synonyms: GA_x6K02T2PVTD-13768406-13767468, MOR145-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258551
Homologene: 133687
Gm7173
Name: predicted gene 7173
Synonyms:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
Fam78b
Name: family with sequence similarity 78, member B
Synonyms: C030020L09Rik, C030014K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226610
Homologene: 18451
Cldn23
Name: claudin 23
Synonyms: 2310014B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71908
Homologene: 12421
Gm10477
Name: predicted gene 10477
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
Homologene: 141188
Ceacam9
Name: carcinoembryonic antigen-related cell adhesion molecule 9
Synonyms: mmCGM8, Cea5, Cea-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 26368
Homologene: 74987
Sap18
Name: Sin3-associated polypeptide 18
Synonyms: Sinbp1, D11Ertd539e, EMegR4, Sap18a, C530046K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 20220
Homologene: 4289
Ccl12
Name: chemokine (C-C motif) ligand 12
Synonyms: MCP-5, Scya12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20293
Homologene: 2245
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,152,549 bp
  • T to C, chromosome 1 at 90,810,365 bp
  • C to A, chromosome 1 at 132,508,109 bp
  • G to A, chromosome 1 at 132,516,512 bp
  • G to A, chromosome 1 at 167,078,709 bp
  • A to G, chromosome 2 at 52,264,064 bp
  • T to A, chromosome 2 at 86,197,996 bp
  • T to A, chromosome 2 at 122,003,892 bp
  • T to C, chromosome 2 at 157,033,325 bp
  • G to C, chromosome 2 at 180,996,456 bp
  • T to C, chromosome 3 at 16,205,192 bp
  • G to A, chromosome 3 at 40,694,146 bp
  • A to T, chromosome 3 at 62,340,283 bp
  • A to G, chromosome 3 at 63,364,753 bp
  • T to C, chromosome 3 at 107,926,914 bp
  • A to C, chromosome 3 at 108,375,176 bp
  • G to A, chromosome 4 at 63,376,900 bp
  • T to C, chromosome 4 at 138,588,569 bp
  • A to T, chromosome 5 at 77,060,758 bp
  • T to A, chromosome 5 at 88,460,758 bp
  • G to A, chromosome 5 at 108,795,332 bp
  • T to A, chromosome 7 at 16,722,003 bp
  • T to A, chromosome 7 at 18,681,022 bp
  • A to G, chromosome 7 at 27,036,646 bp
  • A to T, chromosome 7 at 45,288,462 bp
  • G to A, chromosome 7 at 109,026,737 bp
  • T to C, chromosome 7 at 122,127,781 bp
  • T to C, chromosome 7 at 140,926,444 bp
  • A to G, chromosome 8 at 14,934,820 bp
  • T to C, chromosome 8 at 22,667,217 bp
  • A to G, chromosome 8 at 35,826,235 bp
  • T to C, chromosome 8 at 64,085,557 bp
  • A to G, chromosome 8 at 106,664,210 bp
  • T to G, chromosome 9 at 20,027,501 bp
  • T to C, chromosome 9 at 58,824,058 bp
  • T to C, chromosome 9 at 96,295,014 bp
  • A to G, chromosome 9 at 112,136,670 bp
  • T to C, chromosome 10 at 42,534,646 bp
  • G to T, chromosome 11 at 26,459,841 bp
  • T to C, chromosome 11 at 73,053,478 bp
  • T to A, chromosome 11 at 82,101,950 bp
  • T to A, chromosome 11 at 100,567,011 bp
  • T to C, chromosome 11 at 113,649,598 bp
  • A to G, chromosome 12 at 104,389,682 bp
  • T to C, chromosome 13 at 12,403,264 bp
  • A to G, chromosome 13 at 13,660,971 bp
  • T to G, chromosome 13 at 25,119,285 bp
  • T to A, chromosome 13 at 27,199,342 bp
  • T to A, chromosome 13 at 37,025,679 bp
  • T to A, chromosome 14 at 57,798,554 bp
  • A to T, chromosome 14 at 67,023,128 bp
  • G to A, chromosome 14 at 78,299,893 bp
  • T to C, chromosome 14 at 80,021,113 bp
  • C to T, chromosome 15 at 28,297,005 bp
  • G to A, chromosome 15 at 30,669,514 bp
  • A to G, chromosome 15 at 88,963,431 bp
  • C to T, chromosome 15 at 89,790,776 bp
  • A to G, chromosome 16 at 32,760,238 bp
  • A to T, chromosome 17 at 8,977,215 bp
  • T to C, chromosome 17 at 24,055,966 bp
  • C to T, chromosome 17 at 35,847,943 bp
  • T to A, chromosome 17 at 75,310,159 bp
  • T to A, chromosome 17 at 84,671,147 bp
  • T to C, chromosome 18 at 34,796,780 bp
  • A to T, chromosome 18 at 37,896,389 bp
  • A to G, chromosome 18 at 80,129,170 bp
  • G to T, chromosome 19 at 8,839,782 bp
  • A to G, chromosome 19 at 23,254,666 bp
  • T to A, chromosome X at 56,504,868 bp
  • A to G, chromosome X at 56,524,832 bp
  • T to C, chromosome X at 79,510,321 bp
  • A to G, chromosome X at 91,780,095 bp
  • A to T, chromosome X at 124,133,742 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2121 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040125-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.