Strain Name:
C57BL/6J-MtgxR2137Btlr/Mmmh
Stock Number:
040140-MU
Citation ID:
RRID:MMRRC_040140-MU
Other Names:
R2137 (G1), C57BL/6J-MtgxR2137Btlr
Major Collection:

Gene Information

Fgg
Name: fibrinogen gamma chain
Synonyms: gamma-fibrinogen, 3010002H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99571
HGNC: HGNC:3694
Homologene: 429
Zfp809
Name: zinc finger protein 809
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235047
VEGA: 9
HGNC: null
Homologene: null
Atm
Name: ataxia telangiectasia mutated
Synonyms: C030026E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11920
HGNC: HGNC:795
Homologene: 30952
Scg3
Name: secretogranin III
Synonyms: 1B1075, Chgd, SgIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20255
VEGA: 9
Homologene: 7526
Gria4
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Synonyms: Gluralpha4, Glur4, spkw1, Glur-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 14802
HGNC: HGNC:4574
Homologene: 20227
Wfs1
Name: wolframin ER transmembrane glycoprotein
Synonyms: wolframin, Wolfram syndrome 1 homolog (human)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22393
Homologene: 4380
Rfc1
Name: replication factor C (activator 1) 1
Synonyms: Alp145, 140kDa, RFC140, Recc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19687
HGNC: HGNC:9969
Homologene: 2187
Rheb
Name: Ras homolog enriched in brain
Synonyms: Rheb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19744
Homologene: 123916
Nampt
Name: nicotinamide phosphoribosyltransferase
Synonyms: 1110035O14Rik, Pbef1, Visfatin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 59027
VEGA: 12
Homologene: 4201
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Ncor2
Name: nuclear receptor co-repressor 2
Synonyms: SMRT, SMRTe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20602
HGNC: HGNC:7673
Homologene: 31370
Glyr1
Name: glyoxylate reductase 1 homolog (Arabidopsis)
Synonyms: 3930401K13Rik, Npac, 2810419J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74022
VEGA: 16
Homologene: 12525
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: hyrt, 2310001H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67095
Homologene: 25103
Slc10a4
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231290
Homologene: 15495
Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Synonyms: RPB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231329
HGNC: HGNC:9188
Homologene: 722
Nmbr
Name: neuromedin B receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18101
HGNC: HGNC:7843
Homologene: 20560
Gm9847
Name: predicted pseudogene 9847
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100043256
VEGA: 12
HGNC: null
Homologene: null
Ripor2
Name: RHO family interacting cell polarization regulator 2
Synonyms: Fam65b, 1700108N18Rik, 6330500D04Rik, E430013J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 193385
Homologene: 9284
Il6st
Name: interleukin 6 signal transducer
Synonyms: 5133400A03Rik, CD130, gp130, D13Ertd699e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16195
HGNC: HGNC:6021
Homologene: 1645
Cog1
Name: component of oligomeric golgi complex 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16834
HGNC: HGNC:6545
Homologene: 8411
Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Synonyms: BUBR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12236
HGNC: HGNC:1149
Homologene: 933
Snap29
Name: synaptosomal-associated protein 29
Synonyms: 1300018G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67474
Homologene: 3512
Nudt4
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 4
Synonyms: DIPP2beta, DIPP2alpha, HDCMB47P, DIPP2, 4933436C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71207
VEGA: 10
HGNC: HGNC:8051
Homologene: 41726
Ppp1r21
Name: protein phosphatase 1, regulatory subunit 21
Synonyms: Ccdc128, 1110018J12Rik, Klraq1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73825
Homologene: 44811
Kctd10
Name: potassium channel tetramerisation domain containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330171
Homologene: 32652
Gak
Name: cyclin G associated kinase
Synonyms: D130045N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231580
HGNC: HGNC:4113
Homologene: 3846
Tmem108
Name: transmembrane protein 108
Synonyms: B130017P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 81907
Homologene: 18688
Nphp3
Name: nephronophthisis 3 (adolescent)
Synonyms: nephrocystin 3, pcy, D330020E01Rik, 3632410F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74025
HGNC: HGNC:7907
Homologene: 32697
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Zfp831
Name: zinc finger protein 831
Synonyms: ENSMUSG00000050600, OTTMUSG00000017459
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 100043757
Homologene: 19013
Kif17
Name: kinesin family member 17
Synonyms: 5930435E01Rik, Kif17b, N-4 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16559
Homologene: 5883
Kng2
Name: kininogen 2
Synonyms: Kininogen-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 385643
HGNC: HGNC:6383
Homologene: 88343
Taar1
Name: trace amine-associated receptor 1
Synonyms: Tar1, Trar1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 111174
VEGA: 10
Homologene: 24938
Rin2
Name: Ras and Rab interactor 2
Synonyms: 4632403N06Rik, 2010003K16Rik, RASSF4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74030
Homologene: 32430
Cdh7
Name: cadherin 7, type 2
Synonyms: CDH7L1, 9330156F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241201
HGNC: HGNC:1766
Homologene: 68391
Il1f8
Name: interleukin 1 family, member 8
Synonyms: 2310043N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 69677
Homologene: 18278
Vmn2r10
Name: vomeronasal 2, receptor 10
Synonyms: VR16, V2r16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22307
HGNC: null
Homologene: 129606
Phactr1
Name: phosphatase and actin regulator 1
Synonyms: 9630030F18Rik, Rpel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218194
Homologene: 33597
Klhl32
Name: kelch-like 32
Synonyms: 6430524H05Rik, LOC384000, D4Ertd389e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 212390
Homologene: 14173
Adamts19
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240322
VEGA: 18
Homologene: 15860
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: C80743, 2310067L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69700
Homologene: 43567
Tuba3b
Name: tubulin, alpha 3B
Synonyms: Tuba7, M[a]7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22147
Homologene: 128229
Col4a2
Name: collagen, type IV, alpha 2
Synonyms: Col4a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12827
HGNC: HGNC:2203
Homologene: 1390
Thbs2
Name: thrombospondin 2
Synonyms: Thrombospondin-2, Thbs-2, TSP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21826
VEGA: 17
Homologene: 2438
Grik1
Name: glutamate receptor, ionotropic, kainate 1
Synonyms: D16Ium24e, Glurbeta1, A830007B11Rik, D16Ium24, Glur-5, GluK5, Glur5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 14805
HGNC: HGNC:4579
Homologene: 68992
Olfr870
Name: olfactory receptor 870
Synonyms: MOR141-1, GA_x6K02T2PVTD-13912679-13911744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 57251
HGNC: null
Homologene: 138319
Mss51
Name: MSS51 mitochondrial translational activator
Synonyms: 4833444M15Rik, Zmynd17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 74843
VEGA: 14
Homologene: 27997
Ankrd24
Name: ankyrin repeat domain 24
Synonyms: 5730519E19Rik, 4631433D01Rik, D10Bur2e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70615
Homologene: 49885
Lats1
Name: large tumor suppressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16798
VEGA: 10
HGNC: HGNC:6514
Homologene: 55843
Zfp202
Name: zinc finger protein 202
Synonyms: C130037E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 80902
Homologene: 68317
Itprid1
Name: ITPR interacting domain containing 1
Synonyms: Ccdc129, D530004J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232016
Homologene: 52344
Slc35c2
Name: solute carrier family 35, member C2
Synonyms: CGI-15, D2Wsu58e, Ovcov1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228875
Homologene: 6581
Pgm2
Name: phosphoglucomutase 2
Synonyms: 3230402E02Rik, Pgm1, Pgm-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66681
HGNC: HGNC:8906
Homologene: 6693
Tnk2
Name: tyrosine kinase, non-receptor, 2
Synonyms: activated p21cdc42Hs kinase, ACK1, P21cdc42Hs kinase, Pyk1, Ack
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 51789
Homologene: 4224
Rcbtb2
Name: regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
Synonyms: 2810420M18Rik, Chc1l, Rc/btb2, 2610028E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105670
HGNC: HGNC:1914
Homologene: 970
Slc47a1
Name: solute carrier family 47, member 1
Synonyms: MATE1, 1300013J15Rik, mMATE1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67473
Homologene: 34364
Olfr1475
Name: olfactory receptor 1475
Synonyms: MOR202-36, GA_x6K02T2RE5P-3812807-3811863
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258298
HGNC: null
Homologene: 77370
Ugt1a9
Name: UDP glucuronosyltransferase 1 family, polypeptide A9
Synonyms: A12, mUGTBr/P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 394434
Homologene: 133281
Plod3
Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Synonyms: lysyl hydroxylase 3, LH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26433
HGNC: HGNC:9083
Homologene: 843
AC148991.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
Olfr1480
Name: olfactory receptor 1480
Synonyms: GA_x6K02T2RE5P-3862389-3863336, MOR202-44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 404339
HGNC: null
Homologene: 110492
Cdh22
Name: cadherin 22
Synonyms: PB-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 104010
Homologene: 23148
Galntl6
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
Synonyms: 1700021K10Rik, 4930431L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270049
Homologene: 65137
Myoz2
Name: myozenin 2
Synonyms: Fatz-2, calsarcin-1, 1110012I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 59006
HGNC: HGNC:1330
Homologene: 9583
AC159899.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Mbd3l2
Name: methyl-CpG binding domain protein 3-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234988
VEGA: 9
Homologene: 44896
Klf1
Name: Kruppel-like factor 1 (erythroid)
Synonyms: Eklf, Nan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16596
HGNC: HGNC:6345
Homologene: 4785
1700084C06Rik
Name: RIKEN cDNA 1700084C06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: null
HGNC: null
Homologene: null
Zfp213
Name: zinc finger protein 213
Synonyms: D17Ertd197e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 449521
VEGA: 17
Homologene: 55809
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 88,071,037 bp
  • A to T, chromosome 1 at 110,100,106 bp
  • T to C, chromosome 2 at 13,336,167 bp
  • A to G, chromosome 2 at 24,154,660 bp
  • G to T, chromosome 2 at 118,636,718 bp
  • C to T, chromosome 2 at 145,860,446 bp
  • G to A, chromosome 2 at 165,116,394 bp
  • A to G, chromosome 2 at 165,281,379 bp
  • A to G, chromosome 2 at 174,705,746 bp
  • A to T, chromosome 3 at 83,008,438 bp
  • G to A, chromosome 3 at 123,034,212 bp
  • A to T, chromosome 4 at 24,629,275 bp
  • T to A, chromosome 4 at 138,262,667 bp
  • A to G, chromosome 5 at 24,807,603 bp
  • T to C, chromosome 5 at 36,967,501 bp
  • A to T, chromosome 5 at 64,116,366 bp
  • A to G, chromosome 5 at 65,311,039 bp
  • C to T, chromosome 5 at 73,007,580 bp
  • T to A, chromosome 5 at 77,320,346 bp
  • C to T, chromosome 5 at 108,606,877 bp
  • A to T, chromosome 5 at 109,003,544 bp
  • A to G, chromosome 5 at 114,367,328 bp
  • A to T, chromosome 5 at 125,030,712 bp
  • C to A, chromosome 5 at 136,988,717 bp
  • A to G, chromosome 6 at 55,889,189 bp
  • A to G, chromosome 6 at 145,618,833 bp
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp
  • T to C, chromosome 8 at 11,433,749 bp
  • C to T, chromosome 8 at 58,535,905 bp
  • C to T, chromosome 8 at 84,903,146 bp
  • T to G, chromosome 9 at 4,427,026 bp
  • A to T, chromosome 9 at 18,444,958 bp
  • T to A, chromosome 9 at 20,171,167 bp
  • A to G, chromosome 9 at 21,110,985 bp
  • T to C, chromosome 9 at 22,235,138 bp
  • T to C, chromosome 9 at 40,209,758 bp
  • A to T, chromosome 9 at 53,453,375 bp
  • A to T, chromosome 9 at 75,676,810 bp
  • G to A, chromosome 9 at 99,232,492 bp
  • T to A, chromosome 9 at 103,499,963 bp
  • C to A, chromosome 9 at 104,032,069 bp
  • T to A, chromosome 9 at 121,472,962 bp
  • T to C, chromosome 10 at 7,701,847 bp
  • TAAA to TAAAAAAA, chromosome 10 at 14,760,720 bp
  • T to C, chromosome 10 at 23,921,270 bp
  • C to T, chromosome 10 at 81,646,309 bp
  • T to C, chromosome 10 at 95,563,738 bp
  • T to A, chromosome 11 at 61,344,492 bp
  • T to C, chromosome 11 at 113,659,301 bp
  • T to C, chromosome 11 at 116,221,839 bp
  • G to T, chromosome 12 at 14,495,081 bp
  • T to A, chromosome 12 at 32,830,310 bp
  • G to A, chromosome 13 at 24,721,834 bp
  • T to G, chromosome 13 at 43,135,175 bp
  • C to A, chromosome 13 at 112,502,858 bp
  • T to C, chromosome 14 at 20,487,523 bp
  • G to A, chromosome 14 at 73,162,051 bp
  • T to C, chromosome 15 at 72,006,948 bp
  • T to C, chromosome 16 at 5,018,482 bp
  • C to A, chromosome 16 at 17,428,249 bp
  • G to T, chromosome 16 at 22,997,326 bp
  • G to T, chromosome 16 at 32,670,802 bp
  • C to A, chromosome 16 at 87,946,536 bp
  • T to A, chromosome 17 at 14,673,306 bp
  • T to C, chromosome 17 at 23,559,507 bp
  • T to C, chromosome 17 at 88,542,834 bp
  • C to A, chromosome 18 at 59,048,984 bp
  • A to T, chromosome 19 at 10,997,331 bp
  • A to G, chromosome 19 at 13,479,809 bp
  • T to A, chromosome 19 at 13,530,438 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2137 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040140-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.